CS36292A3 - Pyridine compounds - Google Patents
Pyridine compounds Download PDFInfo
- Publication number
- CS36292A3 CS36292A3 CS92362A CS36292A CS36292A3 CS 36292 A3 CS36292 A3 CS 36292A3 CS 92362 A CS92362 A CS 92362A CS 36292 A CS36292 A CS 36292A CS 36292 A3 CS36292 A3 CS 36292A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- group
- alkyl
- carbon atoms
- formula
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919102803A GB9102803D0 (en) | 1991-02-11 | 1991-02-11 | Pyridine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS36292A3 true CS36292A3 (en) | 1992-08-12 |
Family
ID=10689812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS92362A CS36292A3 (en) | 1991-02-11 | 1992-02-07 | Pyridine compounds |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US5236936A (de) |
| EP (1) | EP0499416A3 (de) |
| JP (1) | JPH05140107A (de) |
| KR (1) | KR920016421A (de) |
| AU (1) | AU640302B2 (de) |
| CA (1) | CA2060945A1 (de) |
| CS (1) | CS36292A3 (de) |
| FI (1) | FI920563L (de) |
| GB (2) | GB9102803D0 (de) |
| HU (1) | HUT60263A (de) |
| IE (1) | IE920131A1 (de) |
| IL (1) | IL100714A0 (de) |
| MX (1) | MX9200560A (de) |
| NO (1) | NO920266L (de) |
| ZA (1) | ZA92394B (de) |
| ZW (1) | ZW1392A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5332750A (en) * | 1991-09-04 | 1994-07-26 | Merck Patent Gesellschaft Mit Beschrankter Haftung | 1,2-dihydro-2-oxopyridines |
| GB9121727D0 (en) * | 1991-10-14 | 1991-11-27 | Ici Plc | Heterocyclic compounds |
| FR2687674B1 (fr) * | 1992-02-07 | 1995-05-19 | Roussel Uclaf | Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| DE4314964A1 (de) * | 1993-05-06 | 1994-11-10 | Bayer Ag | Pyridinylmethyl-substiutierte Pyridine und Pyridone |
| GB9510477D0 (en) * | 1995-05-24 | 1995-07-19 | Sandoz Ltd | Organic compounds |
| SE9903028D0 (sv) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
| GB0225548D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Compounds |
| WO2006094799A2 (en) * | 2005-03-04 | 2006-09-14 | Glaxo Group Limited | Pyridinone derivatives against malaria |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2627848T3 (es) | 2008-06-04 | 2017-07-31 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EP2968439A2 (de) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Zusammensetzungen zur behandlung von magen-darm-störungen |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| PL3004138T3 (pl) | 2013-06-05 | 2024-07-29 | Bausch Health Ireland Limited | Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie |
| JP2017206440A (ja) * | 2014-09-10 | 2017-11-24 | 日本曹達株式会社 | ピリジン化合物およびその用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| US4820843A (en) * | 1987-05-22 | 1989-04-11 | E. I. Du Pont De Nemours And Company | Tetrazole intermediates to antihypertensive compounds |
| US4880804A (en) * | 1988-01-07 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking benzimidazoles |
| US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
| ATE117294T1 (de) * | 1989-08-11 | 1995-02-15 | Ici Plc | Chinolin-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel. |
| CA2037630C (en) * | 1990-03-07 | 2001-07-03 | Akira Morimoto | Nitrogen-containing heterocylic compounds, their production and use |
| GB2244054B (en) * | 1990-04-19 | 1994-04-06 | Ici Plc | Pyridine derivatives |
| KR100196559B1 (ko) * | 1990-06-19 | 1999-06-15 | 기따사또 이찌로 | 안지오텐신ii 길항작용을 함유하는 피리딘 유도체 |
| IL99246A0 (en) * | 1990-09-10 | 1992-07-15 | Abbott Lab | Angiotensin ii receptor antagonists and pharmaceutical compositions containing them |
-
1991
- 1991-02-11 GB GB919102803A patent/GB9102803D0/en active Pending
-
1992
- 1992-01-16 IE IE013192A patent/IE920131A1/en unknown
- 1992-01-20 IL IL100714A patent/IL100714A0/xx unknown
- 1992-01-20 NO NO92920266A patent/NO920266L/no unknown
- 1992-01-20 HU HU9200177A patent/HUT60263A/hu unknown
- 1992-01-20 ZA ZA92394A patent/ZA92394B/xx unknown
- 1992-01-22 AU AU10411/92A patent/AU640302B2/en not_active Expired - Fee Related
- 1992-01-27 ZW ZW13/92A patent/ZW1392A1/xx unknown
- 1992-02-07 GB GB929202586A patent/GB9202586D0/en active Pending
- 1992-02-07 EP EP19920301049 patent/EP0499416A3/en not_active Withdrawn
- 1992-02-07 CS CS92362A patent/CS36292A3/cs unknown
- 1992-02-10 KR KR1019920002018A patent/KR920016421A/ko not_active Withdrawn
- 1992-02-10 CA CA002060945A patent/CA2060945A1/en not_active Abandoned
- 1992-02-10 MX MX9200560A patent/MX9200560A/es unknown
- 1992-02-11 FI FI920563A patent/FI920563L/fi not_active Application Discontinuation
- 1992-02-11 US US07/834,037 patent/US5236936A/en not_active Expired - Fee Related
- 1992-02-12 JP JP4025285A patent/JPH05140107A/ja active Pending
-
1993
- 1993-06-14 US US08/076,330 patent/US5380730A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI920563A0 (fi) | 1992-02-11 |
| KR920016421A (ko) | 1992-09-24 |
| GB9202586D0 (en) | 1992-03-25 |
| CA2060945A1 (en) | 1992-08-12 |
| MX9200560A (es) | 1992-08-01 |
| US5380730A (en) | 1995-01-10 |
| GB9102803D0 (en) | 1991-03-27 |
| AU640302B2 (en) | 1993-08-19 |
| US5236936A (en) | 1993-08-17 |
| NO920266L (no) | 1992-08-12 |
| FI920563A7 (fi) | 1992-08-12 |
| NO920266D0 (no) | 1992-01-20 |
| EP0499416A3 (en) | 1992-10-21 |
| IE920131A1 (en) | 1992-08-12 |
| IL100714A0 (en) | 1992-09-06 |
| HUT60263A (en) | 1992-08-28 |
| ZA92394B (en) | 1992-10-28 |
| FI920563L (fi) | 1992-08-12 |
| HU9200177D0 (en) | 1992-04-28 |
| JPH05140107A (ja) | 1993-06-08 |
| ZW1392A1 (en) | 1992-09-07 |
| EP0499416A2 (de) | 1992-08-19 |
| AU1041192A (en) | 1992-08-13 |
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