CS258534B1 - Derivatives of valeronitrile and method of their preparation - Google Patents
Derivatives of valeronitrile and method of their preparation Download PDFInfo
- Publication number
- CS258534B1 CS258534B1 CS865462A CS546286A CS258534B1 CS 258534 B1 CS258534 B1 CS 258534B1 CS 865462 A CS865462 A CS 865462A CS 546286 A CS546286 A CS 546286A CS 258534 B1 CS258534 B1 CS 258534B1
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- isopropyl
- valeronitrile
- toluene
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS865462A CS258534B1 (en) | 1986-07-18 | 1986-07-18 | Derivatives of valeronitrile and method of their preparation |
| JP62174016A JPS6330460A (ja) | 1986-07-18 | 1987-07-14 | ２−イソプロピル−２−フェニル−５−（ｎ−メチル−２−フェニルエチルアミノ）バレロニトリル誘導体 |
| EP87306319A EP0257768A1 (fr) | 1986-07-18 | 1987-07-17 | Dérivés de 2-isopropyl-2-phényl-5-(N-méthyl-2-phényl-éthylamino)valéronitrile et des procédés pour leur préparation |
| US07/074,801 US4847403A (en) | 1986-07-18 | 1987-07-17 | 2-Isopropyl-2-(2-methylphenyl)-5-(N-methyl-N-homoveratrylamino)-valeronitrile and method for producing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS865462A CS258534B1 (en) | 1986-07-18 | 1986-07-18 | Derivatives of valeronitrile and method of their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS546286A1 CS546286A1 (en) | 1987-12-17 |
| CS258534B1 true CS258534B1 (en) | 1988-08-16 |
Family
ID=5399560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS865462A CS258534B1 (en) | 1986-07-18 | 1986-07-18 | Derivatives of valeronitrile and method of their preparation |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4847403A (fr) |
| EP (1) | EP0257768A1 (fr) |
| JP (1) | JPS6330460A (fr) |
| CS (1) | CS258534B1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5891261A (ja) * | 1981-11-27 | 1983-05-31 | 株式会社アイジ−技術研究所 | 外装構造 |
| PT96284A (pt) * | 1989-12-21 | 1991-09-30 | Searle & Co | Processo para a preparacao de derivados de omega-amino-alfa-fenilalcanonitrilo |
| US5162569A (en) * | 1989-12-21 | 1992-11-10 | G. D. Searle & Co. | Phenylacetonitrilealkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives |
| US5247119A (en) * | 1990-12-12 | 1993-09-21 | G. D. Searle & Co. | Phenylacetonitrilehydroxyalkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1154810B (de) * | 1961-04-01 | 1963-09-26 | Knoll Ag | Verfahren zur Herstellung basisch substituierter Phenylacetonitrile |
| DE3034221A1 (de) * | 1980-09-11 | 1982-04-22 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung basisch substituierter phenylacetonitrile |
| DE3144150A1 (de) * | 1981-04-10 | 1982-12-09 | Basf Ag, 6700 Ludwigshafen | (omega)-cyan-1,(omega)-diphenyl-azaalkan-derivate, ihre herstellung und diese enthaltende arzneimittel |
| US4612329A (en) * | 1984-10-17 | 1986-09-16 | Hokuriku Pharmaceutical Co., Ltd. | Pharmaceutical alpha-aminoalkyl-alpha-alkylphenylacetonitriles |
-
1986
- 1986-07-18 CS CS865462A patent/CS258534B1/cs unknown
-
1987
- 1987-07-14 JP JP62174016A patent/JPS6330460A/ja active Pending
- 1987-07-17 US US07/074,801 patent/US4847403A/en not_active Expired - Fee Related
- 1987-07-17 EP EP87306319A patent/EP0257768A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CS546286A1 (en) | 1987-12-17 |
| EP0257768A1 (fr) | 1988-03-02 |
| US4847403A (en) | 1989-07-11 |
| JPS6330460A (ja) | 1988-02-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5296482A (en) | (Benzocycloalkyl) alkylamines | |
| JP2637737B2 (ja) | 新規な薬剤 | |
| IE77776B1 (en) | New 5-isoquinolinesulfonamides process for preparing them and pharmaceutical compositions containing them | |
| FR2581993A1 (fr) | Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique | |
| DK156513B (da) | Analogifremgangsmaade til fremstilling af omega-cyan-1,-omega-diphenyl-azaalkanderivater eller salte deraf med fysiologisk acceptable syrer | |
| PT87361B (pt) | Processo para a preparacao de di-hidropiridinas | |
| Atwal et al. | Substituted 1, 2, 3, 4-tetrahydroaminonaphthols: antihypertensive agents, calcium channel blockers, and adrenergic receptor blockers with catecholamine-depleting effects | |
| CA1079639A (fr) | Derives de la 3-benzazepine | |
| CS258534B1 (en) | Derivatives of valeronitrile and method of their preparation | |
| JPS6040422B2 (ja) | 置換１‐アルキルチオフエニル―２，３，４，５―テトラヒドロ―１ｈ―３―ベンズアゼピン化合物 | |
| US3317545A (en) | [2-(2, 6-dimethylpiperidino)ethyl]guanidines and intermediates | |
| WO2003016313A1 (fr) | Nouveaux composes de traitement de l'impuissance | |
| EP0304271A2 (fr) | Acides oméga-arylsulphonamidoalkanoiques pour le traitement de maladies par médiation du thromboxane | |
| US3898224A (en) | 1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds | |
| EP0157399A2 (fr) | Composés (5H-dibenzo[a,d]cycloheptem-5-yl)-4-pipéridine | |
| CA1090334A (fr) | Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro- 1h-3-benzazepines a action dopaminergique | |
| US5643947A (en) | ω-amino-α-phenylalkanonitrile derivatives | |
| JP4528304B2 (ja) | ペンタフルオロスルファニルベンゾイルグアニジン、その製造方法、医薬又は診断薬としてのその使用及びそれらを含有する医薬 | |
| US3479371A (en) | 3-((1-cyano-2-lower alkyl)amino)-2-hydroxypropoxyindoles | |
| EP0103500B1 (fr) | Dérivés de phénéthyl-1alpha-phényl-pipéridine-3-propanenitrile, leur préparation et leur application en thérapeutique | |
| KR840001034B1 (ko) | 디하이드로니코틴산 유도체의 제조방법 | |
| FR2571965A1 (fr) | Medicaments a base de nouveaux derives de la 4 h-dioxino-(4,5-c)-pyridine. | |
| EP0106860B1 (fr) | Nouvelles carboxamidoguanidines, leur procede d'obtention et les compositions pharmaceutiques en renfermant | |
| US4833162A (en) | Substituted benzeneacetonitriles and their use as calcium channel blockers | |
| WO1999006351A1 (fr) | Procede permettant de convertir des amino-n-oxydes propargyliques en enaminones |