CS241142B2 - Organic tissues freezing method - Google Patents
Organic tissues freezing method Download PDFInfo
- Publication number
- CS241142B2 CS241142B2 CS839225A CS922583A CS241142B2 CS 241142 B2 CS241142 B2 CS 241142B2 CS 839225 A CS839225 A CS 839225A CS 922583 A CS922583 A CS 922583A CS 241142 B2 CS241142 B2 CS 241142B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- decompression
- freezing
- cell
- tissue
- pressure
- Prior art date
Links
- 238000007710 freezing Methods 0.000 title claims abstract description 24
- 230000008014 freezing Effects 0.000 title claims abstract description 21
- 238000000034 method Methods 0.000 title claims abstract description 17
- 239000007789 gas Substances 0.000 claims abstract description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 230000010355 oscillation Effects 0.000 claims description 2
- 230000006837 decompression Effects 0.000 abstract description 44
- 238000010257 thawing Methods 0.000 abstract description 15
- 239000012530 fluid Substances 0.000 abstract description 12
- 230000008569 process Effects 0.000 abstract description 9
- 230000006378 damage Effects 0.000 abstract description 6
- 210000003850 cellular structure Anatomy 0.000 abstract description 4
- 230000001413 cellular effect Effects 0.000 abstract description 2
- 230000008016 vaporization Effects 0.000 abstract 1
- 238000009834 vaporization Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 30
- 210000001519 tissue Anatomy 0.000 description 15
- 241000196324 Embryophyta Species 0.000 description 12
- 239000000463 material Substances 0.000 description 12
- 238000001816 cooling Methods 0.000 description 11
- 239000013078 crystal Substances 0.000 description 11
- 241001465754 Metazoa Species 0.000 description 10
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 9
- 241000699670 Mus sp. Species 0.000 description 9
- 240000003768 Solanum lycopersicum Species 0.000 description 9
- 239000000126 substance Substances 0.000 description 8
- 241000208822 Lactuca Species 0.000 description 7
- 235000003228 Lactuca sativa Nutrition 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 7
- 210000002421 cell wall Anatomy 0.000 description 7
- 238000005755 formation reaction Methods 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 235000013399 edible fruits Nutrition 0.000 description 4
- 230000008020 evaporation Effects 0.000 description 4
- 238000001704 evaporation Methods 0.000 description 4
- 210000002977 intracellular fluid Anatomy 0.000 description 4
- 235000013311 vegetables Nutrition 0.000 description 4
- 230000018044 dehydration Effects 0.000 description 3
- 238000006297 dehydration reaction Methods 0.000 description 3
- 239000011368 organic material Substances 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 240000006740 Cichorium endivia Species 0.000 description 2
- 235000003953 Solanum lycopersicum var cerasiforme Nutrition 0.000 description 2
- 240000003040 Solanum lycopersicum var. cerasiforme Species 0.000 description 2
- 230000003444 anaesthetic effect Effects 0.000 description 2
- 210000004102 animal cell Anatomy 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 230000005779 cell damage Effects 0.000 description 2
- 208000037887 cell injury Diseases 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- 230000006790 cellular biosynthetic process Effects 0.000 description 2
- 235000003733 chicria Nutrition 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 235000012055 fruits and vegetables Nutrition 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 241001474374 Blennius Species 0.000 description 1
- 235000007516 Chrysanthemum Nutrition 0.000 description 1
- 240000005250 Chrysanthemum indicum Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 208000010378 Pulmonary Embolism Diseases 0.000 description 1
- 208000027520 Somatoform disease Diseases 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000008618 cell wall macromolecule catabolic process Effects 0.000 description 1
- 230000036755 cellular response Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000036449 good health Effects 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000005580 one pot reaction Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 208000027753 pain disease Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000005496 tempering Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
- A23B7/00—Preservation or chemical ripening of fruit or vegetables
- A23B7/04—Freezing; Subsequent thawing; Cooling
- A23B7/0425—Freezing; Subsequent thawing; Cooling the material not being transported through or in the apparatus, with or without shaping, e.g. in the form of powder, granules or flakes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0278—Physical preservation processes
- A01N1/0289—Pressure processes, i.e. using a designated change in pressure over time
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Fruits And Vegetables (AREA)
- Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
- Freezing, Cooling And Drying Of Foods (AREA)
- Battery Electrode And Active Subsutance (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/448,467 US4423600A (en) | 1982-12-10 | 1982-12-10 | Method for preservation of living organic tissue by freezing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS922583A2 CS922583A2 (en) | 1985-07-16 |
| CS241142B2 true CS241142B2 (en) | 1986-03-13 |
Family
ID=23780414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS839225A CS241142B2 (en) | 1982-12-10 | 1983-12-08 | Organic tissues freezing method |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4423600A (fi) |
| EP (1) | EP0127673A4 (fi) |
| KR (1) | KR900008739B1 (fi) |
| AU (1) | AU560371B2 (fi) |
| CA (1) | CA1211981A (fi) |
| CS (1) | CS241142B2 (fi) |
| DD (1) | DD213590A5 (fi) |
| ES (1) | ES8500718A1 (fi) |
| FI (1) | FI85306C (fi) |
| GR (1) | GR78713B (fi) |
| IL (1) | IL70350A0 (fi) |
| IN (1) | IN161673B (fi) |
| IT (1) | IT1208445B (fi) |
| MA (1) | MA19973A1 (fi) |
| MX (1) | MX168928B (fi) |
| NO (1) | NO843193L (fi) |
| NZ (1) | NZ206408A (fi) |
| OA (1) | OA07786A (fi) |
| PT (1) | PT77795B (fi) |
| RO (1) | RO91902B (fi) |
| WO (1) | WO1984002389A1 (fi) |
| YU (1) | YU240383A (fi) |
| ZA (1) | ZA838998B (fi) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4799361A (en) * | 1983-08-23 | 1989-01-24 | Board Of Regents, The University Of Texas System | Method for cryopreparing biological tissue for ultrastructural analysis |
| US4865871A (en) * | 1983-08-23 | 1989-09-12 | Board Of Regents The University Of Texas System | Method for cryopreparing biological tissue |
| US4676070A (en) * | 1984-11-30 | 1987-06-30 | The Board Of Regents, The University Of Texas | Apparatus and method for cryopreparing biological tissue |
| GB8323094D0 (en) * | 1983-08-26 | 1983-09-28 | Franks F | Preservation of cells |
| US4688387A (en) * | 1985-11-12 | 1987-08-25 | Vital Force, Inc. | Method for preservation and storage of viable biological materials at cryogenic temperatures |
| US5044165A (en) * | 1986-12-03 | 1991-09-03 | Board Of Regents, The University Of Texas | Cryo-slammer |
| US4890457A (en) * | 1987-01-02 | 1990-01-02 | Cryolife, Inc. | Method for cryopreserving heart valves |
| GB8716039D0 (en) * | 1987-07-08 | 1987-08-12 | Cell Systems Ltd | Biological chilling protection |
| US5100676A (en) * | 1990-02-02 | 1992-03-31 | Biosurface Technology, Inc. | Cool storage of cultured epithelial sheets |
| CH683485A5 (fr) * | 1990-11-20 | 1994-03-31 | Pasteur Merieux Serums Vacc | Solutions de perfusion, de conservation et de reperfusion d'organes. |
| US5160313A (en) * | 1991-05-14 | 1992-11-03 | Cryolife, Inc. | Process for preparing tissue for transplantation |
| US6238706B1 (en) * | 1999-05-06 | 2001-05-29 | Grofish L.L.C. | Method of stimulating growth in aquatic animals using growth hormones |
| DE102004061947A1 (de) * | 2004-12-22 | 2006-07-06 | Ccs Cell Culture Service Gmbh | Verfahren zum Einfrieren und Lagern von Zellen |
| JP2011511623A (ja) * | 2008-01-17 | 2011-04-14 | ヴァンス プロダクツ インコーポレイテッド | ガラス化のための急冷装置 |
| US8394624B2 (en) * | 2009-01-30 | 2013-03-12 | American Air Liquide, Inc. | Process for preserving biological materials for extended periods of time |
| US9379368B2 (en) | 2011-07-11 | 2016-06-28 | California Institute Of Technology | Electrochemical systems with electronically conductive layers |
| US9255261B2 (en) | 2014-02-07 | 2016-02-09 | Qol Medical Llc | Ultrapure hypoallergenic solutions of sacrosidase |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR385503A (fr) * | 1907-12-23 | 1908-05-15 | Jules Boudry | Procédé de conservation des produits alimentaires à l'état frais et appareil servant à l'appliquer |
| US1422627A (en) * | 1918-09-05 | 1922-07-11 | Shaw John Coutts | Process of chilling and freezing animal substances |
| US2304192A (en) * | 1940-08-16 | 1942-12-08 | Honeywell Regulator Co | Refrigeration of hygroscopic material |
| FR911025A (fr) * | 1944-05-10 | 1946-06-26 | Dispositif de conservation perfectionné de matières périssables réfrigérées | |
| US2507527A (en) * | 1945-07-13 | 1950-05-16 | Koppers Co Inc | Chemical process |
| US2786342A (en) * | 1954-03-25 | 1957-03-26 | Charles E Goetz | Vacuum cooling |
| US2894845A (en) * | 1955-04-18 | 1959-07-14 | Gen Electric | Methods of preserving fresh foods |
| US2832690A (en) * | 1955-08-08 | 1958-04-29 | Western Vegets Le Ind Inc | Method of cooling and preserving lettuce and leafy vegetables |
| US3077036A (en) * | 1959-01-10 | 1963-02-12 | Leybold Hochvakuum Anlagen | Temperature responsive freeze drying method and apparatus |
| FR1274401A (fr) * | 1959-07-06 | 1961-10-27 | Expl De Procedes Ind Soc Et | Procédé de préparation de greffons cornéens |
| US3110163A (en) * | 1959-12-21 | 1963-11-12 | Wells A Webb | Mobile vacuum cooling plant |
| US3082097A (en) * | 1960-07-25 | 1963-03-19 | Allen C Blakely | Process for preserving perishable products by refrigeration |
| US3219463A (en) * | 1962-02-09 | 1965-11-23 | Lamb Weston Inc | Process of dehydrofreezing foods |
| US3180738A (en) * | 1962-12-12 | 1965-04-27 | Ralston Purina Co | Treatment of precooked fish |
| FR1371112A (fr) * | 1963-10-11 | 1964-08-28 | Leybolds Nachfolger E | Procédé et dispositif pour la conservation par le vide de denrées périssables |
| US3413818A (en) * | 1963-12-13 | 1968-12-03 | Fmc Corp | Immersion freezing |
| US3320757A (en) * | 1966-04-15 | 1967-05-23 | Cryobank Inc | Cryogenic preserver |
| AT292436B (de) * | 1967-10-05 | 1971-08-25 | Armin Dr Starke | Vorrichtung zum Absorbieren gasförmiger Stoffe in feste, teilchenförmige Stoffe |
| FR2110903A5 (en) * | 1970-10-02 | 1972-06-02 | Kidson Christoffel | Perishable goods handling plant - for storage or transport using continuous air extraction and optional refrigeration |
| JPS5016855B2 (fi) * | 1971-09-10 | 1975-06-17 | ||
| US4252001A (en) * | 1977-01-21 | 1981-02-24 | Musschoot A | Method and apparatus for cooling foundry sand |
| FR2496436B1 (fr) * | 1980-12-19 | 1985-12-06 | Fritsch Sa | Procede d'acheminement des aliments pour cuisines collectives en liaison froide et appareils pour l'application de ce procede |
-
1982
- 1982-12-10 US US06/448,467 patent/US4423600A/en not_active Expired - Fee Related
-
1983
- 1983-10-29 IN IN1334/CAL/83A patent/IN161673B/en unknown
- 1983-11-28 CA CA000442035A patent/CA1211981A/en not_active Expired
- 1983-11-28 NZ NZ206408A patent/NZ206408A/en unknown
- 1983-11-29 IL IL70350A patent/IL70350A0/xx unknown
- 1983-11-30 GR GR73107A patent/GR78713B/el unknown
- 1983-11-30 EP EP19840900223 patent/EP0127673A4/en not_active Withdrawn
- 1983-11-30 AU AU23470/84A patent/AU560371B2/en not_active Ceased
- 1983-11-30 WO PCT/US1983/001888 patent/WO1984002389A1/en not_active Application Discontinuation
- 1983-12-02 ZA ZA838998A patent/ZA838998B/xx unknown
- 1983-12-06 ES ES527829A patent/ES8500718A1/es not_active Expired
- 1983-12-08 CS CS839225A patent/CS241142B2/cs unknown
- 1983-12-09 PT PT77795A patent/PT77795B/pt unknown
- 1983-12-09 MA MA20194A patent/MA19973A1/fr unknown
- 1983-12-09 YU YU02403/83A patent/YU240383A/xx unknown
- 1983-12-09 MX MX199691A patent/MX168928B/es unknown
- 1983-12-09 IT IT8349477A patent/IT1208445B/it active
- 1983-12-09 DD DD83257728A patent/DD213590A5/de unknown
- 1983-12-10 KR KR1019830005858A patent/KR900008739B1/ko not_active IP Right Cessation
-
1984
- 1984-07-24 FI FI842954A patent/FI85306C/fi not_active IP Right Cessation
- 1984-08-02 OA OA58358A patent/OA07786A/xx unknown
- 1984-08-08 RO RO115453A patent/RO91902B/ro unknown
- 1984-08-09 NO NO843193A patent/NO843193L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| OA07786A (en) | 1986-11-20 |
| NZ206408A (en) | 1986-09-10 |
| MA19973A1 (fr) | 1984-07-01 |
| YU240383A (en) | 1985-10-31 |
| IL70350A0 (en) | 1984-02-29 |
| ES527829A0 (es) | 1984-11-01 |
| NO843193L (no) | 1984-08-09 |
| PT77795B (fr) | 1986-03-25 |
| RO91902B (ro) | 1987-07-01 |
| FI85306C (fi) | 1992-03-25 |
| ES8500718A1 (es) | 1984-11-01 |
| AU2347084A (en) | 1984-07-05 |
| CA1211981A (en) | 1986-09-30 |
| IN161673B (fi) | 1988-01-16 |
| MX168928B (es) | 1993-06-14 |
| DD213590A5 (de) | 1984-09-19 |
| WO1984002389A1 (en) | 1984-06-21 |
| PT77795A (fr) | 1984-01-01 |
| RO91902A (ro) | 1987-06-30 |
| KR900008739B1 (ko) | 1990-11-29 |
| GR78713B (fi) | 1984-09-27 |
| US4423600A (en) | 1984-01-03 |
| IT1208445B (it) | 1989-06-12 |
| FI85306B (fi) | 1991-12-13 |
| FI842954A0 (fi) | 1984-07-24 |
| EP0127673A4 (en) | 1988-07-14 |
| KR840007023A (ko) | 1984-12-04 |
| AU560371B2 (en) | 1987-04-02 |
| ZA838998B (en) | 1984-07-25 |
| CS922583A2 (en) | 1985-07-16 |
| FI842954A (fi) | 1984-07-24 |
| EP0127673A1 (en) | 1984-12-12 |
| IT8349477A0 (it) | 1983-12-09 |
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