CS222209B2 - Method of making the m-dioxan-5-methylamine and their pharmaceutically utilisable addition salts with acids - Google Patents

Method of making the m-dioxan-5-methylamine and their pharmaceutically utilisable addition salts with acids

Info

Publication number
CS222209B2
CS222209B2 CS765892A CS589276A CS222209B2 CS 222209 B2 CS222209 B2 CS 222209B2 CS 765892 A CS765892 A CS 765892A CS 589276 A CS589276 A CS 589276A CS 222209 B2 CS222209 B2 CS 222209B2
Authority
CS
Czechoslovakia
Prior art keywords
dioxan
methylamine
acids
making
addition salts
Prior art date
Application number
CS765892A
Other languages
Czech (cs)
English (en)
Inventor
Richard N Bouher
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS222209B2 publication Critical patent/CS222209B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS765892A 1972-12-08 1973-12-10 Method of making the m-dioxan-5-methylamine and their pharmaceutically utilisable addition salts with acids CS222209B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31322172A 1972-12-08 1972-12-08

Publications (1)

Publication Number Publication Date
CS222209B2 true CS222209B2 (en) 1983-05-27

Family

ID=23214841

Family Applications (3)

Application Number Title Priority Date Filing Date
CS765892A CS222209B2 (en) 1972-12-08 1973-12-10 Method of making the m-dioxan-5-methylamine and their pharmaceutically utilisable addition salts with acids
CS738529A CS222208B2 (en) 1972-12-08 1973-12-10 Method of making the m-dioxan-5-methylamine and their pharmaceutically utilizable addition salts with the acids
CS738528A CS193480B2 (en) 1972-12-08 1973-12-10 Method of producing m-dioxane-5-methylamines and their pharmaceutically usable acid additive salts

Family Applications After (2)

Application Number Title Priority Date Filing Date
CS738529A CS222208B2 (en) 1972-12-08 1973-12-10 Method of making the m-dioxan-5-methylamine and their pharmaceutically utilizable addition salts with the acids
CS738528A CS193480B2 (en) 1972-12-08 1973-12-10 Method of producing m-dioxane-5-methylamines and their pharmaceutically usable acid additive salts

Country Status (27)

Country Link
JP (2) JPS5742633B2 (ja)
AR (3) AR206306A1 (ja)
AT (2) AT332396B (ja)
BE (1) BE808340A (ja)
BG (4) BG26205A4 (ja)
CA (2) CA1014560A (ja)
CH (4) CH605903A5 (ja)
CS (3) CS222209B2 (ja)
CY (1) CY1017A (ja)
DD (3) DD115653A5 (ja)
DE (1) DE2361340C2 (ja)
DK (1) DK134717B (ja)
ES (4) ES421290A1 (ja)
FR (1) FR2209578B1 (ja)
GB (2) GB1455997A (ja)
HK (1) HK60479A (ja)
HU (2) HU168620B (ja)
IE (1) IE40226B1 (ja)
IL (1) IL43773A (ja)
KE (1) KE2976A (ja)
MY (1) MY8000064A (ja)
NL (1) NL7316839A (ja)
PH (2) PH15197A (ja)
SE (3) SE403377B (ja)
SU (4) SU578001A3 (ja)
YU (3) YU36171B (ja)
ZA (1) ZA739207B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2847177B1 (en) * 2012-05-09 2017-10-11 Boehringer Ingelheim International GmbH Methods for making oxetan-3-ylmethanamines
LV14983B (lv) * 2013-10-15 2015-06-20 Olainfarm, A/S Fenibuta ražošanas starpproduktu iegūšanas paņēmiens

Also Published As

Publication number Publication date
JPS4987681A (ja) 1974-08-22
ZA739207B (en) 1975-07-30
CH614439A5 (en) 1979-11-30
ES444716A1 (es) 1977-05-16
DE2361340A1 (de) 1974-06-12
DD110864A5 (ja) 1975-01-12
YU36171B (en) 1982-02-25
CY1017A (en) 1979-11-23
HU168620B (ja) 1976-06-28
PH15197A (en) 1982-09-17
SU648081A3 (ru) 1979-02-15
ES421291A1 (es) 1976-07-01
YU318473A (en) 1980-09-25
BE808340A (fr) 1974-06-07
CS222208B2 (en) 1983-05-27
AR212012A1 (es) 1978-04-28
DK134717C (ja) 1977-05-31
SU587861A3 (ru) 1978-01-05
MY8000064A (en) 1980-12-31
YU35447B (en) 1981-02-28
KE2976A (en) 1979-07-20
CA1014560A (en) 1977-07-26
FR2209578B1 (ja) 1977-09-02
YU36020B (en) 1981-11-13
JPS5742633B2 (ja) 1982-09-09
AU6321773A (en) 1975-06-05
GB1455998A (en) 1976-11-17
CH630914A5 (en) 1982-07-15
YU109380A (en) 1981-04-30
NL7316839A (ja) 1974-06-11
BG21223A3 (ja) 1976-03-20
JPS4987680A (ja) 1974-08-22
DD115653A5 (ja) 1975-10-12
IL43773A0 (en) 1974-03-14
SU578001A3 (ru) 1977-10-25
IE40226B1 (en) 1979-04-11
ATA1026073A (de) 1975-10-15
IL43773A (en) 1979-05-31
AT330773B (de) 1976-07-26
YU318573A (en) 1981-06-30
GB1455997A (en) 1976-11-17
DK134717B (da) 1977-01-03
ES444911A1 (es) 1977-09-01
AR212416A1 (es) 1978-07-14
ES421290A1 (es) 1976-07-01
DE2361340C2 (de) 1983-11-24
CH619219A5 (en) 1980-09-15
IE40226L (en) 1974-06-08
CS193480B2 (en) 1979-10-31
CA1024150A (en) 1978-01-10
AR206306A1 (es) 1976-07-15
SU663305A3 (ru) 1979-05-15
DD109625A5 (ja) 1974-11-12
ATA1026173A (de) 1976-01-15
BG22386A3 (ja) 1977-02-20
SE417196B (sv) 1981-03-02
SE7701796L (sv) 1977-02-17
JPS5734835B2 (ja) 1982-07-26
SE403377B (sv) 1978-08-14
FR2209578A1 (ja) 1974-07-05
AT332396B (de) 1976-09-27
CH605903A5 (ja) 1978-10-13
BG26205A4 (ja) 1979-02-15
BG21409A3 (ja) 1976-05-20
PH14923A (en) 1982-01-29
SE7701795L (sv) 1977-02-17
HU168763B (ja) 1976-07-28
HK60479A (en) 1979-08-31
SE428378B (sv) 1983-06-27

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