CS212687A3 - Process for preparing compounds with nootropic activity - Google Patents

Process for preparing compounds with nootropic activity

Info

Publication number
CS212687A3
CS212687A3 CS872126A CS212687A CS212687A3 CS 212687 A3 CS212687 A3 CS 212687A3 CS 872126 A CS872126 A CS 872126A CS 212687 A CS212687 A CS 212687A CS 212687 A3 CS212687 A3 CS 212687A3
Authority
CS
Czechoslovakia
Prior art keywords
nootropic activity
preparing compounds
nootropic
activity
prophylaxis
Prior art date
Application number
CS872126A
Other languages
Czech (cs)
English (en)
Other versions
CS276179B6 (en
Inventor
Franz Dr Hock
Josef Prof Dr Scholtholt
Hansjorg Dr Urbach
Rainer Dr Henning
Ulrich Dr Lerch
Wolf-Ulrich Dr Nickel
Wolfgang Dr Ruger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CS212687A3 publication Critical patent/CS212687A3/cs
Publication of CS276179B6 publication Critical patent/CS276179B6/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Epoxy Compounds (AREA)
CS872126A 1986-03-27 1987-03-27 Process for preparing compounds with nootropic activity CS276179B6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863610391 DE3610391A1 (de) 1986-03-27 1986-03-27 Verbindungen mit nootroper wirkung, diese enthaltende mittel und deren verwendung bei der behandlung und prophylaxe cognitiver dysfunktionen

Publications (2)

Publication Number Publication Date
CS212687A3 true CS212687A3 (en) 1992-04-15
CS276179B6 CS276179B6 (en) 1992-04-15

Family

ID=6297417

Family Applications (2)

Application Number Title Priority Date Filing Date
CS896519A CS651989A3 (en) 1986-03-27 1987-03-27 Process for preparing compounds with nootropic effect
CS872126A CS276179B6 (en) 1986-03-27 1987-03-27 Process for preparing compounds with nootropic activity

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS896519A CS651989A3 (en) 1986-03-27 1987-03-27 Process for preparing compounds with nootropic effect

Country Status (25)

Country Link
EP (1) EP0243645B1 (xx)
JP (1) JPS62240698A (xx)
KR (1) KR870008841A (xx)
CN (1) CN1031267C (xx)
AT (1) ATE102954T1 (xx)
AU (1) AU621278B2 (xx)
CA (1) CA1341064C (xx)
CS (2) CS651989A3 (xx)
DD (1) DD280765A5 (xx)
DE (2) DE3610391A1 (xx)
DK (1) DK172221B1 (xx)
EG (1) EG18175A (xx)
ES (1) ES2061447T3 (xx)
FI (1) FI91876C (xx)
HU (2) HU203117B (xx)
IE (1) IE62456B1 (xx)
MA (1) MA20919A1 (xx)
NO (1) NO178546C (xx)
NZ (1) NZ219764A (xx)
OA (1) OA08506A (xx)
PH (1) PH27210A (xx)
PT (1) PT84564B (xx)
RU (1) RU1836335C (xx)
TN (1) TNSN87045A1 (xx)
ZA (1) ZA872230B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
AU612137B2 (en) * 1987-04-27 1991-07-04 E.R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing an ace inhibitor
DE3731085A1 (de) * 1987-09-16 1989-04-06 Hoechst Ag Neue aminosaeureester, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3739690A1 (de) * 1987-11-24 1989-06-08 Hoechst Ag Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen
DE3801587A1 (de) * 1988-01-21 1989-08-03 Hoechst Ag Neue aminosaeureglyceride, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
EP0331609A3 (de) * 1988-01-27 1992-07-01 Hoechst Aktiengesellschaft Angiotensin-Converting-Enzym-Hemmstoffe mit psychotroper Wirkung
DE3803225A1 (de) * 1988-02-04 1989-08-17 Hoechst Ag Aminosaeureamide mit psychotroper wirkung, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung
JPH01275529A (ja) * 1988-03-21 1989-11-06 E R Squibb & Sons Inc 晩発性運動障害の抑制治療剤
US5037821A (en) * 1988-06-01 1991-08-06 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor
US5093129A (en) * 1989-01-30 1992-03-03 E. R. Squibb & Sons, Inc. Method for treating addiction to a drug of abuse employing an ace inhibitor
US5032578A (en) * 1990-09-17 1991-07-16 E. R. Squibb & Sons, Inc. Method for preventing or treating depression employing a combination of an ace inhibitor and a drug that acts at serotonin receptors
JP2004532200A (ja) * 2001-03-15 2004-10-21 サエジス ファーマシューティカルズ， インコーポレイテッド 全身性ストレスの後に認識機能を回復するための方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19575012I2 (de) * 1980-10-23 2002-01-24 Schering Corp Carboxyalkyl-Dipeptide Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE3300774A1 (de) * 1983-01-12 1984-07-12 Hoechst Ag, 6230 Frankfurt Neue spirocyclische aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue spirocyclische aminosaeuren als zwischenprodukte und verfahren zu deren herstellung

Also Published As

Publication number Publication date
NZ219764A (en) 1990-11-27
PT84564B (pt) 1989-11-10
HU896609D0 (en) 1990-02-28
ES2061447T3 (es) 1994-12-16
NO871282L (no) 1987-09-28
EP0243645A2 (de) 1987-11-04
DE3789330D1 (de) 1994-04-21
DK153587D0 (da) 1987-03-26
ZA872230B (en) 1987-09-21
AU7064987A (en) 1987-10-01
IE62456B1 (en) 1995-02-08
OA08506A (fr) 1988-07-29
NO871282D0 (no) 1987-03-26
CS276385B6 (en) 1992-05-13
FI871304A (fi) 1987-09-28
EG18175A (en) 1994-07-30
CN1031267C (zh) 1996-03-13
DK172221B1 (da) 1998-01-12
HU202118B (en) 1991-02-28
KR870008841A (ko) 1987-10-21
MA20919A1 (fr) 1987-10-01
CA1341064C (en) 2000-08-01
IE870784L (en) 1987-09-27
JPS62240698A (ja) 1987-10-21
ATE102954T1 (de) 1994-04-15
CS276179B6 (en) 1992-04-15
CS651989A3 (en) 1992-05-13
DD280765A5 (de) 1990-07-18
NO178546B (no) 1996-01-08
PH27210A (en) 1993-05-04
RU1836335C (ru) 1993-08-23
EP0243645B1 (de) 1994-03-16
HU203117B (en) 1991-05-28
NO178546C (no) 1996-04-17
EP0243645A3 (en) 1990-01-24
FI871304A0 (fi) 1987-03-25
CN87102304A (zh) 1987-12-30
PT84564A (de) 1987-04-01
TNSN87045A1 (fr) 1990-01-01
FI91876C (fi) 1994-08-25
FI91876B (fi) 1994-05-13
AU621278B2 (en) 1992-03-12
DK153587A (da) 1987-09-28
DE3610391A1 (de) 1987-10-08
HUT46046A (en) 1988-09-28

Similar Documents

Publication Publication Date Title
HUT43582A (en) Process for production of derivatives of 4,5,6-substituated-n-/substituated phenil/-piramidin-amin and medical compounds containing thereof
GR860571B (en) Labdan-derivatives process for their preparation and their use as medicaments
CS212687A3 (en) Process for preparing compounds with nootropic activity
IL89031A0 (en) Medicaments containing a benzamide for the treatment or prevention of cognitive disorders and their preparation
ES8503643A1 (es) Un procedimiento para la preparacion de compuestos de bis (carboxamida)
HUT46837A (en) Compositions of insectifuge and acarifuge activity containing alpha, omega-amino-alkohol derivatives as active components and process for producing the active components
PH24568A (en) Use of bezafibrate for treating diabetes
GR3002365T3 (en) Medicines containing as a mixture interferon and 1-desoxy-piperidinoses, process for their manufacture and their use
PT85602A (en) Oxolabdanes a process for their preparation and their use as medicaments
ZA872677B (en) Pharmaceutical compositions for the treatment of intermittent claudication
ES2001577A6 (es) Un procedimiento para preparar compuestos relacionados con espergualina
JO1516B1 (en) Compounds with cognitive effectiveness, factors containing them, and their use in treatment and disease prevention for cognitive dysfunction