CS209915B2 - Method of making the 4-halogenpregna-1,4-dien-3,20-dions - Google Patents
Method of making the 4-halogenpregna-1,4-dien-3,20-dions Download PDFInfo
- Publication number
- CS209915B2 CS209915B2 CS792305A CS230579A CS209915B2 CS 209915 B2 CS209915 B2 CS 209915B2 CS 792305 A CS792305 A CS 792305A CS 230579 A CS230579 A CS 230579A CS 209915 B2 CS209915 B2 CS 209915B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- diene
- dione
- hydroxy
- methyl
- chloro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89364178A | 1978-04-05 | 1978-04-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
CS209915B2 true CS209915B2 (en) | 1981-12-31 |
Family
ID=25401847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS792305A CS209915B2 (en) | 1978-04-05 | 1979-04-04 | Method of making the 4-halogenpregna-1,4-dien-3,20-dions |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0004766A3 (fi) |
JP (1) | JPS54135762A (fi) |
AR (1) | AR224124A1 (fi) |
AT (1) | ATA251679A (fi) |
AU (1) | AU4575379A (fi) |
CS (1) | CS209915B2 (fi) |
DK (1) | DK136379A (fi) |
ES (1) | ES479269A1 (fi) |
FI (1) | FI791080A (fi) |
GR (1) | GR66483B (fi) |
IL (1) | IL56989A0 (fi) |
IT (1) | IT7967708A0 (fi) |
NO (1) | NO791143L (fi) |
PL (1) | PL214677A1 (fi) |
PT (1) | PT69410A (fi) |
ZA (1) | ZA791637B (fi) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4340538A (en) * | 1980-07-21 | 1982-07-20 | The Upjohn Company | Process for producing 6α-fluoro-Δ1,4 -3-keto steroids |
WO2012123482A2 (en) * | 2011-03-15 | 2012-09-20 | Chiesi Farmaceutici S.P.A. | Isoxazolidine derivatives |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3125591A (en) * | 1964-03-17 | Derivatives thereof | ||
FR1273890A (fr) * | 1960-05-14 | 1961-10-20 | Chimiotherapie Lab Franc | Procédé de préparation de stéroïdes 21-bromés |
US3169131A (en) * | 1963-03-29 | 1965-02-09 | Upjohn Co | Process for the preparation of 4-fluorohydrocortisone, 21-acylates and 16-substituted derivatives thereof, and intermediates produced in the preparation thereof |
-
1979
- 1979-03-30 AR AR276017A patent/AR224124A1/es active
- 1979-03-30 PT PT69410A patent/PT69410A/pt unknown
- 1979-03-31 GR GR58745A patent/GR66483B/el unknown
- 1979-04-02 FI FI791080A patent/FI791080A/fi not_active Application Discontinuation
- 1979-04-02 IL IL56989A patent/IL56989A0/xx unknown
- 1979-04-02 EP EP79300542A patent/EP0004766A3/en not_active Withdrawn
- 1979-04-03 DK DK136379A patent/DK136379A/da unknown
- 1979-04-03 AU AU45753/79A patent/AU4575379A/en not_active Abandoned
- 1979-04-04 CS CS792305A patent/CS209915B2/cs unknown
- 1979-04-04 IT IT7967708A patent/IT7967708A0/it unknown
- 1979-04-04 PL PL21467779A patent/PL214677A1/xx unknown
- 1979-04-04 AT AT0251679A patent/ATA251679A/de unknown
- 1979-04-04 NO NO791143A patent/NO791143L/no unknown
- 1979-04-04 ES ES479269A patent/ES479269A1/es not_active Expired
- 1979-04-05 ZA ZA791637A patent/ZA791637B/xx unknown
- 1979-04-05 JP JP4041179A patent/JPS54135762A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AR224124A1 (es) | 1981-10-30 |
IT7967708A0 (it) | 1979-04-04 |
PL214677A1 (fi) | 1980-01-02 |
ZA791637B (en) | 1980-11-26 |
PT69410A (fr) | 1979-04-01 |
NO791143L (no) | 1979-10-08 |
GR66483B (fi) | 1981-03-24 |
IL56989A0 (en) | 1979-07-25 |
JPS54135762A (en) | 1979-10-22 |
EP0004766A3 (en) | 1979-10-31 |
DK136379A (da) | 1979-10-06 |
ES479269A1 (es) | 1980-01-16 |
ATA251679A (de) | 1982-04-15 |
EP0004766A2 (en) | 1979-10-17 |
AU4575379A (en) | 1979-10-11 |
FI791080A (fi) | 1979-10-06 |
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