ZA791637B - 4,6-dihalo steroids - Google Patents

4,6-dihalo steroids

Info

Publication number
ZA791637B
ZA791637B ZA791637A ZA791637A ZA791637B ZA 791637 B ZA791637 B ZA 791637B ZA 791637 A ZA791637 A ZA 791637A ZA 791637 A ZA791637 A ZA 791637A ZA 791637 B ZA791637 B ZA 791637B
Authority
ZA
South Africa
Prior art keywords
dihalo
steroids
dihalo steroids
Prior art date
Application number
ZA791637A
Other languages
English (en)
Inventor
F Alvarez
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA791637B publication Critical patent/ZA791637B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
ZA791637A 1978-04-05 1979-04-05 4,6-dihalo steroids ZA791637B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89364178A 1978-04-05 1978-04-05

Publications (1)

Publication Number Publication Date
ZA791637B true ZA791637B (en) 1980-11-26

Family

ID=25401847

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA791637A ZA791637B (en) 1978-04-05 1979-04-05 4,6-dihalo steroids

Country Status (16)

Country Link
EP (1) EP0004766A3 (xx)
JP (1) JPS54135762A (xx)
AR (1) AR224124A1 (xx)
AT (1) ATA251679A (xx)
AU (1) AU4575379A (xx)
CS (1) CS209915B2 (xx)
DK (1) DK136379A (xx)
ES (1) ES479269A1 (xx)
FI (1) FI791080A (xx)
GR (1) GR66483B (xx)
IL (1) IL56989A0 (xx)
IT (1) IT7967708A0 (xx)
NO (1) NO791143L (xx)
PL (1) PL214677A1 (xx)
PT (1) PT69410A (xx)
ZA (1) ZA791637B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340538A (en) * 1980-07-21 1982-07-20 The Upjohn Company Process for producing 6α-fluoro-Δ1,4 -3-keto steroids
CN103391945B (zh) * 2011-03-15 2016-11-09 奇斯药制品公司 异噁唑烷衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125591A (en) * 1964-03-17 Derivatives thereof
FR1273890A (fr) * 1960-05-14 1961-10-20 Chimiotherapie Lab Franc Procédé de préparation de stéroïdes 21-bromés
US3169131A (en) * 1963-03-29 1965-02-09 Upjohn Co Process for the preparation of 4-fluorohydrocortisone, 21-acylates and 16-substituted derivatives thereof, and intermediates produced in the preparation thereof

Also Published As

Publication number Publication date
PL214677A1 (xx) 1980-01-02
EP0004766A3 (en) 1979-10-31
GR66483B (xx) 1981-03-24
FI791080A (fi) 1979-10-06
JPS54135762A (en) 1979-10-22
IL56989A0 (en) 1979-07-25
AU4575379A (en) 1979-10-11
PT69410A (fr) 1979-04-01
DK136379A (da) 1979-10-06
IT7967708A0 (it) 1979-04-04
ES479269A1 (es) 1980-01-16
AR224124A1 (es) 1981-10-30
ATA251679A (de) 1982-04-15
EP0004766A2 (en) 1979-10-17
NO791143L (no) 1979-10-08
CS209915B2 (en) 1981-12-31

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