CS199280B2 - Method of producing novel esters of thiazolinyl-or thiazinyl-benzimidazole - Google Patents

Method of producing novel esters of thiazolinyl-or thiazinyl-benzimidazole Download PDF

Info

Publication number
CS199280B2
CS199280B2 CS765494A CS549476A CS199280B2 CS 199280 B2 CS199280 B2 CS 199280B2 CS 765494 A CS765494 A CS 765494A CS 549476 A CS549476 A CS 549476A CS 199280 B2 CS199280 B2 CS 199280B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
carbon atoms
amino
align
thiazolin
Prior art date
Application number
CS765494A
Other languages
Czech (cs)
English (en)
Inventor
James H Wikel
Charles J Paget
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS199280B2 publication Critical patent/CS199280B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS765494A 1975-11-19 1976-08-24 Method of producing novel esters of thiazolinyl-or thiazinyl-benzimidazole CS199280B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/633,203 US4008243A (en) 1975-11-19 1975-11-19 Antiviral thiazolinyl or thiazinyl benzimidazole esters

Publications (1)

Publication Number Publication Date
CS199280B2 true CS199280B2 (en) 1980-07-31

Family

ID=24538665

Family Applications (1)

Application Number Title Priority Date Filing Date
CS765494A CS199280B2 (en) 1975-11-19 1976-08-24 Method of producing novel esters of thiazolinyl-or thiazinyl-benzimidazole

Country Status (30)

Country Link
US (1) US4008243A (pt)
JP (1) JPS5265269A (pt)
AR (1) AR218228A1 (pt)
AT (1) AT358029B (pt)
AU (1) AU498521B2 (pt)
BE (1) BE845643A (pt)
BG (1) BG27550A3 (pt)
CA (1) CA1059510A (pt)
CH (1) CH623052A5 (pt)
CS (1) CS199280B2 (pt)
DD (1) DD128675A5 (pt)
DE (1) DE2638552A1 (pt)
DK (1) DK142813B (pt)
ES (2) ES451020A1 (pt)
FR (1) FR2332011A1 (pt)
GB (1) GB1561481A (pt)
GR (1) GR61722B (pt)
HU (1) HU172633B (pt)
IE (1) IE43618B1 (pt)
IL (1) IL50294A (pt)
MX (1) MX4067E (pt)
NL (1) NL7609415A (pt)
NZ (1) NZ181788A (pt)
PH (1) PH13615A (pt)
PL (2) PL105486B1 (pt)
PT (1) PT65488B (pt)
RO (1) RO72653A (pt)
SU (1) SU721003A3 (pt)
YU (1) YU203576A (pt)
ZA (1) ZA765143B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293558A (en) * 1975-10-28 1981-10-06 Eli Lilly And Company Antiviral thiazolinyl benzimidazoles and derivatives
CA1076582A (en) * 1975-10-28 1980-04-29 Charles J. Paget Antiviral thiazolinyl or thiazinyl ketobenzimidazoles
US4191832A (en) * 1979-03-12 1980-03-04 Eli Lilly And Company Separation of syn and anti oximes of 1-sulfonyl-2-aminobenzimidazoles
US4338315A (en) * 1979-11-14 1982-07-06 Eli Lilly And Company Antiviral method employing thiazinyl benzimidazole derivatives
US4401817A (en) * 1981-04-20 1983-08-30 Eli Lilly And Company Carbonyl-substituted 1-sulfonylbenzimidazoles
US4463181A (en) * 1982-04-08 1984-07-31 Eli Lilly And Company Process for removing sulfonyl groups from benzimidazole isomers
US4420479A (en) * 1982-04-08 1983-12-13 Eli Lilly And Company Olefinic benzimidazoles, formulations, and antiviral methods
IL68297A (en) * 1982-04-08 1986-09-30 Lilly Co Eli Process for removing 1-sulfonyl groups from 2-amino-5(6)-substituted benzimidazoles
US4434288A (en) * 1982-04-08 1984-02-28 Eli Lilly And Company Preparation of substituted 1-thiazinyl or 1-thiazolyl-2-aminobenzimidazoles
US4492708A (en) * 1982-09-27 1985-01-08 Eli Lilly And Company Antiviral benzimidazoles
US5508594A (en) * 1994-06-10 1996-04-16 Westinghouse Electric Corp Electric vehicle chassis controller
US6358971B1 (en) 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
WO2008021309A1 (en) * 2006-08-15 2008-02-21 Wyeth Imidazolidin-2-one derivatives useful as pr modulators
WO2008021337A1 (en) 2006-08-15 2008-02-21 Wyeth Oxazinan-2-one derivatives useful as pr modulators
US7618989B2 (en) * 2006-08-15 2009-11-17 Wyeth Tricyclic oxazolidone derivatives useful as PR modulators
US20080045560A1 (en) * 2006-08-15 2008-02-21 Wyeth Pyrrolidine and related derivatives useful as PR modulators
US7649007B2 (en) * 2006-08-15 2010-01-19 Wyeth Llc Oxazolidine derivatives as PR modulators
TW200815428A (en) * 2006-08-15 2008-04-01 Wyeth Corp Oxazolidone derivatives as PR modulators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3749717A (en) * 1971-05-04 1973-07-31 Squibb & Sons Inc Thiazolinyl and thiazinyl derivatives of benzimidazoles
US3825537A (en) * 1972-02-28 1974-07-23 Squibb & Sons Inc 1-thiazolin-2-yl(or thiazin-2-yl)-2-aminobenzimidazoles and derivatives thereof
US3833574A (en) * 1972-07-31 1974-09-03 Squibb & Sons Inc Benzimidazolinone compounds

Also Published As

Publication number Publication date
IE43618B1 (en) 1981-04-08
PT65488B (en) 1978-02-13
IL50294A0 (en) 1976-10-31
IL50294A (en) 1981-03-31
FR2332011A1 (fr) 1977-06-17
ATA636576A (de) 1980-01-15
ZA765143B (en) 1978-04-26
GR61722B (en) 1978-12-28
CH623052A5 (pt) 1981-05-15
GB1561481A (en) 1980-02-20
PL105486B1 (pl) 1979-10-31
NZ181788A (en) 1978-06-20
SU721003A3 (ru) 1980-03-05
PT65488A (en) 1976-09-01
DK386276A (pt) 1977-05-20
RO72653A (ro) 1982-10-11
AU498521B2 (en) 1979-03-15
IE43618L (en) 1977-05-19
DK142813B (da) 1981-02-02
ES461632A1 (es) 1978-06-16
US4008243A (en) 1977-02-15
BE845643A (fr) 1977-02-28
MX4067E (es) 1981-12-02
AR218228A1 (es) 1980-05-30
JPS5265269A (en) 1977-05-30
PH13615A (en) 1980-08-07
DK142813C (pt) 1981-09-21
AT358029B (de) 1980-08-11
PL110781B1 (en) 1980-07-31
ES451020A1 (es) 1977-11-16
DE2638552A1 (de) 1977-06-02
FR2332011B1 (pt) 1980-03-28
YU203576A (en) 1982-05-31
HU172633B (hu) 1978-11-28
AU1698476A (en) 1978-02-23
CA1059510A (en) 1979-07-31
DD128675A5 (de) 1977-12-07
BG27550A3 (en) 1979-11-12
NL7609415A (nl) 1977-05-23

Similar Documents

Publication Publication Date Title
CS199280B2 (en) Method of producing novel esters of thiazolinyl-or thiazinyl-benzimidazole
Petersen et al. Synthesis and hypotensive activity of N-alkyl-N''-cyano-N'-pyridylguanidines
US4492708A (en) Antiviral benzimidazoles
US4118742A (en) Carbonyl-substituted 1-sulfonylbenzimidazoles
JPS6234037B2 (pt)
US4216313A (en) Antiviral thiazinyl benzimidazoles
IE47139B1 (en) 4-substituted-pyrazoles
US4174454A (en) Alkylidenylmethyl-substituted 1-sulfonylbenzimidazoles
US4018790A (en) Substituted 1-sulfonylbenzimidazoles
US4118573A (en) Substituted 1-sulfonylbenzimidazoles
US4401817A (en) Carbonyl-substituted 1-sulfonylbenzimidazoles
US4338315A (en) Antiviral method employing thiazinyl benzimidazole derivatives
US4293558A (en) Antiviral thiazolinyl benzimidazoles and derivatives
US4230868A (en) α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles
US4338329A (en) Antiviral method employing 1-sulfonylbenzimidazoles
CA1079737A (en) 1-sulfonyl-5(6)-substituted-benzimidazoles
US4289782A (en) Antiviral 1-sulfonylbenzimidazoles
JPH0114235B2 (pt)
US3182063A (en) Substituted 4-thiazolidinones and process therefor
KR790001432B1 (ko) 티아졸리닐 또는 티아지닐 벤즈이미다졸 에스테르의 제조방법
KR800001218B1 (ko) 티아졸리닐 케로벤즈아미다졸 및 이의 유도체의 제조방법
CA1074803A (en) 1-thiazolinyl-5(6)-substituted-ben-zimidazoles
KR810000232B1 (ko) 1-티아졸리닐-5(6)-치환-벤즈이미다졸 유도체의 제조방법
KR800001220B1 (ko) 티아졸리닐 케토벤즈이미다졸 및 이의 유도체의 제조방법
CS202559B2 (cs) Způsob výroby l-sulfonylbenzimidazolů, substituovaných na karbonylové skupině