CS198233B2 - Method of preparing 3-bromomethyl cephems - Google Patents

Method of preparing 3-bromomethyl cephems Download PDF

Info

Publication number
CS198233B2
CS198233B2 CS771899A CS189977A CS198233B2 CS 198233 B2 CS198233 B2 CS 198233B2 CS 771899 A CS771899 A CS 771899A CS 189977 A CS189977 A CS 189977A CS 198233 B2 CS198233 B2 CS 198233B2
Authority
CS
Czechoslovakia
Prior art keywords
carboxylate
reaction mixture
halogen
process according
bromomethyl
Prior art date
Application number
CS771899A
Other languages
Czech (cs)
English (en)
Inventor
Gary A Koppel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS198233B2 publication Critical patent/CS198233B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CS771899A 1976-03-22 1977-03-22 Method of preparing 3-bromomethyl cephems CS198233B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/669,366 US4048160A (en) 1976-03-22 1976-03-22 Process for preparation of 7-alkoxy-3-bromomethylcephems

Publications (1)

Publication Number Publication Date
CS198233B2 true CS198233B2 (en) 1980-05-30

Family

ID=24686087

Family Applications (1)

Application Number Title Priority Date Filing Date
CS771899A CS198233B2 (en) 1976-03-22 1977-03-22 Method of preparing 3-bromomethyl cephems

Country Status (30)

Country Link
US (1) US4048160A (de)
JP (1) JPS52113995A (de)
AR (1) AR225589A1 (de)
AT (1) AT352274B (de)
AU (1) AU505100B2 (de)
BE (1) BE852669A (de)
BG (1) BG27756A3 (de)
CA (1) CA1108121A (de)
CH (1) CH632514A5 (de)
CS (1) CS198233B2 (de)
DD (1) DD129914A5 (de)
DE (1) DE2711955C2 (de)
DK (1) DK148097B (de)
ES (1) ES457058A1 (de)
FR (1) FR2345455A1 (de)
GB (1) GB1573933A (de)
GR (1) GR66421B (de)
HU (1) HU174436B (de)
IE (1) IE44695B1 (de)
IL (1) IL51431A (de)
NL (1) NL7703062A (de)
NZ (1) NZ183308A (de)
PH (1) PH12745A (de)
PL (1) PL108100B1 (de)
PT (1) PT66316B (de)
RO (1) RO70257A (de)
SE (1) SE428926B (de)
SU (1) SU845787A3 (de)
YU (1) YU68377A (de)
ZA (1) ZA77712B (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1241657A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
US3637678A (en) * 1969-01-13 1972-01-25 Lilly Co Eli Delta-2 cephalosporin compounds
US3705897A (en) * 1970-07-07 1972-12-12 Lilly Co Eli Method for converting delta**2 cephalosporin to delta**3 cephalosporin
BE794554A (fr) * 1972-01-31 1973-07-26 Lilly Co Eli Nouveaux derives de penicilline et de cephalusporine
US3883518A (en) * 1972-05-15 1975-05-13 Merck & Co Inc 3-Methylene cephalosporins
US3897424A (en) * 1973-07-23 1975-07-29 Lilly Co Eli Process for 7-{62 -amino-7-{60 -methoxy-cephalosporanic acid esters and related compounds

Also Published As

Publication number Publication date
AR225589A1 (es) 1982-04-15
ES457058A1 (es) 1978-08-16
PH12745A (en) 1979-08-09
PT66316B (en) 1978-08-14
IE44695L (en) 1977-09-22
US4048160A (en) 1977-09-13
ATA194577A (de) 1979-02-15
GR66421B (de) 1981-03-20
DD129914A5 (de) 1978-02-15
JPS6121959B2 (de) 1986-05-29
NZ183308A (en) 1978-07-28
DK123077A (da) 1977-09-23
RO70257A (ro) 1982-05-10
PL108100B1 (pl) 1980-03-31
CH632514A5 (de) 1982-10-15
IL51431A0 (en) 1977-04-29
PT66316A (en) 1977-04-01
GB1573933A (en) 1980-08-28
AU2219877A (en) 1978-08-17
FR2345455B1 (de) 1980-02-08
JPS52113995A (en) 1977-09-24
FR2345455A1 (fr) 1977-10-21
SU845787A3 (ru) 1981-07-07
CA1108121A (en) 1981-09-01
AT352274B (de) 1979-09-10
NL7703062A (nl) 1977-09-26
DE2711955C2 (de) 1985-11-28
HU174436B (hu) 1980-01-28
BE852669A (fr) 1977-09-19
YU68377A (en) 1982-06-30
DK148097B (da) 1985-03-04
IL51431A (en) 1980-01-31
SE428926B (sv) 1983-08-01
BG27756A3 (en) 1979-12-12
ZA77712B (en) 1978-09-27
DE2711955A1 (de) 1977-10-06
SE7702735L (sv) 1977-09-23
AU505100B2 (en) 1979-11-08
IE44695B1 (en) 1982-02-24

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