CS194227B2 - Method of producing derivatives of lysergic acid amide - Google Patents
Method of producing derivatives of lysergic acid amideInfo
- Publication number
- CS194227B2 CS194227B2 CS753741A CS374175A CS194227B2 CS 194227 B2 CS194227 B2 CS 194227B2 CS 753741 A CS753741 A CS 753741A CS 374175 A CS374175 A CS 374175A CS 194227 B2 CS194227 B2 CS 194227B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- acid amide
- lysergic acid
- producing derivatives
- derivatives
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HUGO1272A HU169073B (sk) | 1974-05-28 | 1974-05-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CS194227B2 true CS194227B2 (en) | 1979-11-30 |
Family
ID=10996767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS753741A CS194227B2 (en) | 1974-05-28 | 1975-05-28 | Method of producing derivatives of lysergic acid amide |
Country Status (21)
Country | Link |
---|---|
US (1) | US4005089A (sk) |
JP (1) | JPS5218718B2 (sk) |
AT (1) | AT346501B (sk) |
BE (1) | BE829518A (sk) |
BG (1) | BG27374A3 (sk) |
CA (1) | CA1051878A (sk) |
CS (1) | CS194227B2 (sk) |
DD (1) | DD121639A5 (sk) |
DE (1) | DE2523743A1 (sk) |
DK (1) | DK143801C (sk) |
ES (1) | ES437994A1 (sk) |
FI (1) | FI61897C (sk) |
FR (1) | FR2272671B1 (sk) |
GB (1) | GB1474337A (sk) |
HU (1) | HU169073B (sk) |
IL (1) | IL47361A (sk) |
NL (1) | NL7506276A (sk) |
PL (1) | PL98944B1 (sk) |
SE (1) | SE419548B (sk) |
SU (1) | SU625612A3 (sk) |
YU (1) | YU135575A (sk) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4064249A (en) * | 1974-05-28 | 1977-12-20 | Richter Gedeon Vegyeszeti Gyar Rt. | Compounds with ergoline skeleton |
HU172649B (hu) * | 1975-04-24 | 1978-11-28 | Gyogyszerkutato Intezet | Sposob poluchenija novykh biologicheski aktivnykh lizergamidov |
HU172479B (hu) * | 1976-03-09 | 1978-09-28 | Gyogyszerkutato Intezet | Sposob poluchenija novykh soedinenij s ehrgolenovymi i |
JPS577172Y2 (sk) * | 1977-03-17 | 1982-02-10 | ||
JPS582957U (ja) * | 1981-06-30 | 1983-01-10 | 松下電子工業株式会社 | 高圧ナトリウムランプ |
IT1171432B (it) * | 1981-08-03 | 1987-06-10 | Fidia Farmaceutici | Amidi organiche derivate da lipidi azotati utilizzabili come farmaci |
US4675322A (en) * | 1984-12-10 | 1987-06-23 | Eli Lilly And Company | 1-Substituted-6-n-propyl-8β-methylthio-methylergolines |
DD238051A1 (de) * | 1985-06-10 | 1986-08-06 | Dresden Arzneimittel | Verfahren zur herstellung neuer lysergsaeureamide |
EP2515654A4 (en) * | 2009-12-23 | 2013-04-24 | Map Pharmaceuticals Inc | NEW ERGOLINANALOGA |
MX2013015373A (es) | 2011-06-23 | 2014-02-11 | Map Pharmaceuticals Inc | Nuevos analogos de fluoroergolina. |
SG11201403434YA (en) | 2011-12-19 | 2014-09-26 | Map Pharmaceuticals Inc | Novel iso-ergoline derivatives |
SG10201506202RA (en) | 2011-12-21 | 2015-09-29 | Map Pharmaceuticals Inc | Novel neuromodulatory compounds |
US9012640B2 (en) | 2012-06-22 | 2015-04-21 | Map Pharmaceuticals, Inc. | Cabergoline derivatives |
BR112017015487A2 (pt) * | 2015-01-20 | 2018-01-30 | Xoc Pharmaceuticals Inc | Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo |
WO2018223065A1 (en) | 2017-06-01 | 2018-12-06 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2533699A (en) * | 1950-12-12 | Amines containing the king system | ||
US2673850A (en) * | 1951-07-28 | 1954-03-30 | Sandoz Ag | Piperazides of the lysergic acid series |
US2946796A (en) * | 1958-10-15 | 1960-07-26 | Grace W R & Co | Salts of ergot alkaloids |
CH475252A (de) * | 1966-02-08 | 1969-07-15 | Sandoz Ag | Verfahren zur Herstellung neuer Lysergsäure-Derivate |
SE396753B (sv) * | 1970-05-18 | 1977-10-03 | Richter Gedeon Vegyeszet | Analogiforfarande for framstellning av en forening tillhorande dihydrolysergsyraserien |
US3901893A (en) * | 1970-05-18 | 1975-08-26 | Richter Gedeon Vegyeszet | New dihydro-lysergic acid derivative |
IL41409A (en) * | 1972-02-04 | 1977-04-29 | Richter Gedeon Vegyeszet | Lysergic acid amides and process for their preparation |
-
1974
- 1974-05-28 HU HUGO1272A patent/HU169073B/hu unknown
-
1975
- 1975-05-21 AT AT386375A patent/AT346501B/de not_active IP Right Cessation
- 1975-05-22 US US05/579,979 patent/US4005089A/en not_active Expired - Lifetime
- 1975-05-23 GB GB2283775A patent/GB1474337A/en not_active Expired
- 1975-05-25 YU YU01355/75A patent/YU135575A/xx unknown
- 1975-05-26 SE SE7505974A patent/SE419548B/xx unknown
- 1975-05-26 BG BG030088A patent/BG27374A3/xx unknown
- 1975-05-26 DD DD186250A patent/DD121639A5/xx unknown
- 1975-05-26 IL IL47361A patent/IL47361A/xx unknown
- 1975-05-27 SU SU752144199A patent/SU625612A3/ru active
- 1975-05-27 DK DK235175A patent/DK143801C/da not_active IP Right Cessation
- 1975-05-27 CA CA227,849A patent/CA1051878A/en not_active Expired
- 1975-05-27 BE BE156729A patent/BE829518A/xx not_active IP Right Cessation
- 1975-05-27 PL PL1975180710A patent/PL98944B1/pl unknown
- 1975-05-27 FR FR7516377A patent/FR2272671B1/fr not_active Expired
- 1975-05-27 FI FI751537A patent/FI61897C/fi not_active IP Right Cessation
- 1975-05-28 JP JP50063984A patent/JPS5218718B2/ja not_active Expired
- 1975-05-28 NL NL7506276A patent/NL7506276A/xx not_active Application Discontinuation
- 1975-05-28 CS CS753741A patent/CS194227B2/cs unknown
- 1975-05-28 ES ES437994A patent/ES437994A1/es not_active Expired
- 1975-05-28 DE DE19752523743 patent/DE2523743A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JPS5218718B2 (sk) | 1977-05-24 |
SE7505974L (sv) | 1975-12-01 |
FI751537A (sk) | 1975-11-29 |
FI61897B (fi) | 1982-06-30 |
YU135575A (en) | 1982-06-30 |
US4005089A (en) | 1977-01-25 |
FR2272671B1 (sk) | 1978-10-06 |
DK143801C (da) | 1982-03-22 |
DD121639A5 (sk) | 1976-08-12 |
PL98944B1 (pl) | 1978-05-31 |
IL47361A (en) | 1979-11-30 |
DK143801B (da) | 1981-10-12 |
ATA386375A (de) | 1978-03-15 |
BE829518A (fr) | 1975-09-15 |
DK235175A (da) | 1975-11-29 |
HU169073B (sk) | 1976-09-28 |
ES437994A1 (es) | 1977-01-16 |
FR2272671A1 (sk) | 1975-12-26 |
SU625612A3 (ru) | 1978-09-25 |
FI61897C (fi) | 1982-10-11 |
SE419548B (sv) | 1981-08-10 |
AT346501B (de) | 1978-11-10 |
GB1474337A (en) | 1977-05-25 |
BG27374A3 (en) | 1979-10-12 |
NL7506276A (nl) | 1975-12-02 |
CA1051878A (en) | 1979-04-03 |
DE2523743A1 (de) | 1975-12-18 |
JPS516998A (sk) | 1976-01-20 |
IL47361A0 (en) | 1975-07-28 |
AU8142575A (en) | 1976-11-25 |
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