CS138692A3 - Asymmetric synthesis of 3-substituted furanoside compounds - Google Patents

Asymmetric synthesis of 3-substituted furanoside compounds

Info

Publication number
CS138692A3
CS138692A3 CS921386A CS138692A CS138692A3 CS 138692 A3 CS138692 A3 CS 138692A3 CS 921386 A CS921386 A CS 921386A CS 138692 A CS138692 A CS 138692A CS 138692 A3 CS138692 A3 CS 138692A3
Authority
CS
Czechoslovakia
Prior art keywords
compounds
asymmetric synthesis
substituted furanoside
furanoside compounds
substituted
Prior art date
Application number
CS921386A
Other languages
English (en)
Inventor
Yuri E Raifeld
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of CS138692A3 publication Critical patent/CS138692A3/cs
Publication of CZ283306B6 publication Critical patent/CZ283306B6/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • C07C247/02Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/04Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • C07C247/02Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C247/08Compounds containing azido groups with azido groups bound to acyclic carbon atoms of a carbon skeleton being unsaturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40Halogenated unsaturated alcohols
    • C07C33/42Halogenated unsaturated alcohols acyclic
    • C07C33/423Halogenated unsaturated alcohols acyclic containing only double bonds as unsaturation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/003Compounds containing elements of Groups 4 or 14 of the Periodic System without C-Metal linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epoxy Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS921386A 1991-05-10 1992-05-07 Asymetrická syntéza 3-substituovaných furanosidových sloučenin CZ283306B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/698,042 US5216145A (en) 1991-05-10 1991-05-10 Asymmetric synthesis of 3-substituted furanoside compounds

Publications (2)

Publication Number Publication Date
CS138692A3 true CS138692A3 (en) 1992-11-18
CZ283306B6 CZ283306B6 (cs) 1998-02-18

Family

ID=24803685

Country Status (24)

Country Link
US (2) US5216145A (cs)
EP (1) EP0540807B1 (cs)
JP (1) JPH05170782A (cs)
KR (1) KR920021526A (cs)
CN (1) CN1032062C (cs)
AT (1) ATE132125T1 (cs)
AU (1) AU657129B2 (cs)
CA (1) CA2068226A1 (cs)
CZ (1) CZ283306B6 (cs)
DE (1) DE69207154T2 (cs)
DK (1) DK0540807T3 (cs)
ES (1) ES2083608T3 (cs)
FI (1) FI922097A (cs)
GR (1) GR3018671T3 (cs)
HU (1) HU209838B (cs)
IE (1) IE75888B1 (cs)
IL (3) IL116971A (cs)
NO (1) NO178113C (cs)
NZ (1) NZ242639A (cs)
PH (1) PH31630A (cs)
PL (1) PL168588B1 (cs)
SK (1) SK279311B6 (cs)
TW (1) TW223068B (cs)
ZA (1) ZA923350B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216145A (en) * 1991-05-10 1993-06-01 American Cyanamid Company Asymmetric synthesis of 3-substituted furanoside compounds
US5521294A (en) * 1995-01-18 1996-05-28 Eli Lilly And Company 2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides
TW200606159A (en) * 2004-07-30 2006-02-16 Pharmaessentia Corp Stereoselective synthesis of β-nucleosides
TWI368621B (en) * 2005-05-02 2012-07-21 Leyoung Biotech Co Ltd Stereoselective synthesis of β-nucleosides
AU2008323923A1 (en) * 2007-11-06 2009-05-14 Pharmaessentia Corporation Novel synthesis of beta-nucleosides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216145A (en) * 1991-05-10 1993-06-01 American Cyanamid Company Asymmetric synthesis of 3-substituted furanoside compounds

Also Published As

Publication number Publication date
HU9201546D0 (en) 1992-07-28
NZ242639A (en) 1993-10-26
CN1032062C (zh) 1996-06-19
US5296620A (en) 1994-03-22
FI922097A0 (fi) 1992-05-08
CA2068226A1 (en) 1992-11-11
DE69207154T2 (de) 1996-09-05
PL168588B1 (pl) 1996-03-29
IL101799A0 (en) 1992-12-30
IE921483A1 (en) 1992-11-18
DE69207154D1 (de) 1996-02-08
IL116971A0 (en) 1996-05-14
IL101799A (en) 1998-04-05
ZA923350B (en) 1993-01-27
HUT61562A (en) 1993-01-28
HU209838B (en) 1994-11-28
GR3018671T3 (en) 1996-04-30
NO921837D0 (no) 1992-05-08
EP0540807B1 (en) 1995-12-27
NO178113B (no) 1995-10-16
JPH05170782A (ja) 1993-07-09
ES2083608T3 (es) 1996-04-16
AU1613292A (en) 1992-11-12
DK0540807T3 (da) 1996-01-29
CZ283306B6 (cs) 1998-02-18
FI922097A (fi) 1992-11-11
KR920021526A (ko) 1992-12-18
TW223068B (cs) 1994-05-01
US5216145A (en) 1993-06-01
EP0540807A1 (en) 1993-05-12
PH31630A (en) 1999-01-12
NO921837L (no) 1992-11-11
SK279311B6 (sk) 1998-09-09
NO178113C (no) 1996-01-24
IE75888B1 (en) 1997-09-24
IL116971A (en) 1999-03-12
AU657129B2 (en) 1995-03-02
CN1066658A (zh) 1992-12-02
ATE132125T1 (de) 1996-01-15

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20000507