CR9416A - Tigecycline compositions and methods of preparation - Google Patents

Tigecycline compositions and methods of preparation

Info

Publication number
CR9416A
CR9416A CR9416A CR9416A CR9416A CR 9416 A CR9416 A CR 9416A CR 9416 A CR9416 A CR 9416A CR 9416 A CR9416 A CR 9416A CR 9416 A CR9416 A CR 9416A
Authority
CR
Costa Rica
Prior art keywords
methods
compositions
preparation
tigecycline
tigecycline compositions
Prior art date
Application number
CR9416A
Other languages
English (en)
Inventor
Mahdi B Fawzi
Tianmin Zhu
Syed M Shah
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36648809&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR9416(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CR9416A publication Critical patent/CR9416A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

La presente invencion relaciona a las composiciones mejoradas de tigeciclina y los metodos para hacer tales composiciones. Las composiciones inventivas han mejorado la estabilidad en ambos estados, solido y solucion. Las composiciones inventivas comprenden la tigeciclina, un carbohidrato adecuado y un acido o solucion tampon.
CR9416A 2005-03-14 2007-10-04 Tigecycline compositions and methods of preparation CR9416A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66103005P 2005-03-14 2005-03-14

Publications (1)

Publication Number Publication Date
CR9416A true CR9416A (es) 2008-03-06

Family

ID=36648809

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9416A CR9416A (es) 2005-03-14 2007-10-04 Tigecycline compositions and methods of preparation

Country Status (25)

Country Link
US (5) US7879828B2 (es)
EP (1) EP1858488B2 (es)
JP (1) JP4972081B2 (es)
KR (2) KR20130122988A (es)
CN (2) CN101132775A (es)
AR (2) AR053827A1 (es)
AU (1) AU2006223226B2 (es)
BR (1) BRPI0608464A2 (es)
CA (1) CA2602089C (es)
CR (1) CR9416A (es)
CY (1) CY1114504T1 (es)
DK (1) DK1858488T4 (es)
ES (1) ES2434944T5 (es)
GT (1) GT200600112A (es)
HN (1) HN2006011218A (es)
IL (1) IL185924A (es)
MX (1) MX2007010983A (es)
NO (1) NO20074278L (es)
PE (1) PE20061107A1 (es)
PL (1) PL1858488T5 (es)
PT (1) PT1858488E (es)
RU (1) RU2428190C2 (es)
TW (1) TW200700092A (es)
WO (1) WO2006099258A1 (es)
ZA (1) ZA200707831B (es)

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AR057649A1 (es) * 2005-05-27 2007-12-12 Wyeth Corp Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas
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PT2271348T (pt) * 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
US9107929B2 (en) 2008-05-01 2015-08-18 Ranbaxy Laboratories Limited Stable parenteral formulations of tigecycline
WO2010017273A2 (en) * 2008-08-06 2010-02-11 Wyeth Tigecycline formulations
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KR101799304B1 (ko) * 2010-05-12 2017-11-20 렘펙스 파머수티클스 인코퍼레이티드 테트라사이클린 조성물
CN104645318B (zh) 2011-06-07 2021-11-02 旭化成制药株式会社 高纯度含pth冷冻干燥制剂及其制造方法
CN102391148B (zh) * 2011-10-24 2014-01-08 江苏奥赛康药业股份有限公司 一种高纯度替加环素的合成方法
CN103315947B (zh) 2012-03-22 2016-01-20 上海汇伦生命科技有限公司 一种注射用替加环素组合物
CN103356662B (zh) * 2012-03-27 2015-11-25 浙江医药股份有限公司新昌制药厂 注射用替加环素组合物及其制备方法
CN102641249A (zh) * 2012-05-06 2012-08-22 江苏奥赛康药业股份有限公司 一种替加环素组合物的制备方法
CN103417498B (zh) * 2012-05-18 2017-09-12 山东新时代药业有限公司 一种替加环素冻干粉针剂的制备方法
CN102697739B (zh) * 2012-05-31 2014-10-29 丽珠医药集团股份有限公司 一种减少替加环素差向异构体化的粉针剂制备方法
CN102911077B (zh) * 2012-11-12 2015-01-07 成都百裕科技制药有限公司 4r-替加环素的制备方法
WO2014167575A2 (en) 2013-03-26 2014-10-16 Astron Research Limited Stable tigecycline composition
IN2013MU01127A (es) 2013-03-26 2015-05-01 Astron Res Ltd
CN104107170A (zh) * 2013-04-22 2014-10-22 上海汇伦生命科技有限公司 一种替加环素组合物
US20140323443A1 (en) * 2013-04-30 2014-10-30 Fresenius Kabi Usa, Llc Tigecycline formulations
EP3068370A2 (en) 2013-11-12 2016-09-21 Galenicum Health S.L. Stable pharmaceutical compositions
NO2723977T3 (es) 2014-03-19 2018-03-10
CN105079816B (zh) * 2015-08-17 2018-09-07 江苏豪森药业集团有限公司 替加环素药物组合物及其制备方法
CN108653216B (zh) * 2018-05-28 2020-12-18 福安药业集团湖北人民制药有限公司 注射用替加环素
WO2021063468A1 (en) 2019-10-02 2021-04-08 Anfarm Hellas S.A. Stable parenteral pharmaceutical composition containing tigecycline and process for the preparation thereof
IT202100031133A1 (it) 2021-12-13 2023-06-13 Zambon Spa Composizione farmaceutica comprendente tigeciclina

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Also Published As

Publication number Publication date
CY1114504T1 (el) 2016-10-05
US9694078B2 (en) 2017-07-04
US20160144036A1 (en) 2016-05-26
AU2006223226B2 (en) 2012-03-15
AU2006223226A1 (en) 2006-09-21
PL1858488T3 (pl) 2014-01-31
MX2007010983A (es) 2007-09-19
US20150141379A1 (en) 2015-05-21
TW200700092A (en) 2007-01-01
DK1858488T4 (da) 2022-09-12
KR101354093B1 (ko) 2014-01-24
ZA200707831B (en) 2011-02-23
US20170266290A1 (en) 2017-09-21
KR20080002828A (ko) 2008-01-04
RU2428190C2 (ru) 2011-09-10
JP2008533146A (ja) 2008-08-21
DK1858488T3 (da) 2013-11-04
PL1858488T5 (pl) 2024-01-03
US8975242B2 (en) 2015-03-10
BRPI0608464A2 (pt) 2010-01-05
US20110118216A1 (en) 2011-05-19
IL185924A (en) 2014-05-28
IL185924A0 (en) 2008-01-06
WO2006099258A1 (en) 2006-09-21
NO20074278L (no) 2007-11-20
CN102512429A (zh) 2012-06-27
KR20130122988A (ko) 2013-11-11
JP4972081B2 (ja) 2012-07-11
US9254328B2 (en) 2016-02-09
CA2602089A1 (en) 2006-09-21
WO2006099258A8 (en) 2007-10-04
RU2007131396A (ru) 2009-04-20
AR109500A2 (es) 2018-12-19
PE20061107A1 (es) 2006-12-08
US20060247181A1 (en) 2006-11-02
EP1858488A1 (en) 2007-11-28
EP1858488B2 (en) 2022-07-20
ES2434944T3 (es) 2013-12-18
ES2434944T5 (es) 2022-10-20
AR053827A1 (es) 2007-05-23
US7879828B2 (en) 2011-02-01
CN101132775A (zh) 2008-02-27
US10588975B2 (en) 2020-03-17
GT200600112A (es) 2006-11-29
HN2006011218A (es) 2008-09-17
EP1858488B1 (en) 2013-09-11
PT1858488E (pt) 2013-11-18
CA2602089C (en) 2013-04-30

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