CR9401A - Compuestos aromaticos condensados con actividad antidiabetica - Google Patents
Compuestos aromaticos condensados con actividad antidiabeticaInfo
- Publication number
- CR9401A CR9401A CR9401A CR9401A CR9401A CR 9401 A CR9401 A CR 9401A CR 9401 A CR9401 A CR 9401A CR 9401 A CR9401 A CR 9401A CR 9401 A CR9401 A CR 9401A
- Authority
- CR
- Costa Rica
- Prior art keywords
- aromatic compounds
- antidiabetic activity
- compounds condensed
- diabetes
- type
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Abstract
Compuestos aromaticos condensados de formula I que son agonistas o agonistas parciales de PPAR gamma y son utiles en el tratamiento o control de diabetes tipo II, incluyendo hiperglucemia, dislipidemia, hiperlipidemia, hipercolesterolemia, hipertrigliceridemia y obesidad que estan con frecuencia asociados con diabetes tipo 2.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65866105P | 2005-03-04 | 2005-03-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR9401A true CR9401A (es) | 2008-02-21 |
Family
ID=36615702
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR9401A CR9401A (es) | 2005-03-04 | 2007-09-27 | Compuestos aromaticos condensados con actividad antidiabetica |
Country Status (18)
Country | Link |
---|---|
US (1) | US7834036B2 (es) |
EP (1) | EP1861382B1 (es) |
JP (1) | JP4638512B2 (es) |
KR (1) | KR20070110324A (es) |
CN (2) | CN102584754B (es) |
AU (1) | AU2006220809B2 (es) |
BR (1) | BRPI0609352A2 (es) |
CA (1) | CA2598725C (es) |
CR (1) | CR9401A (es) |
ES (1) | ES2393793T3 (es) |
IL (1) | IL185394A0 (es) |
MA (1) | MA29352B1 (es) |
MX (1) | MX2007010745A (es) |
NI (1) | NI200700200A (es) |
NO (1) | NO20075000L (es) |
RU (1) | RU2007136784A (es) |
WO (1) | WO2006096564A1 (es) |
ZA (1) | ZA200706394B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007103252A2 (en) * | 2006-03-03 | 2007-09-13 | Merck & Co., Inc. | Novel crystalline forms of antidiabetic compounds |
WO2008109334A1 (en) | 2007-03-02 | 2008-09-12 | Merck & Co., Inc. | Novel crystalline salt form of an antidiabetic compound |
US11241420B2 (en) | 2007-04-11 | 2022-02-08 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
US20160331729A9 (en) | 2007-04-11 | 2016-11-17 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
US8338458B2 (en) * | 2007-05-07 | 2012-12-25 | Merck Sharp & Dohme Corp. | Method of treatment using fused aromatic compounds having anti-diabetic activity |
US20120035105A1 (en) * | 2009-01-09 | 2012-02-09 | Sdg, Inc. | Insulin Therapies for the Treatment of Diabetes, Diabetes Related Ailments, and/or Diseases or Conditions Other Than Diabetes or Diabetes Related Ailments |
WO2014134776A1 (en) * | 2013-03-04 | 2014-09-12 | Merck Sharp & Dohme Corp. | Compounds inhibiting leucine-rich repeat kinase enzyme activity |
CN104725219B (zh) * | 2015-02-11 | 2017-08-08 | 华中农业大学 | S‑2‑(4‑甲氧基苯氧基)丙酸钠的制备方法 |
MX2018013413A (es) | 2016-05-26 | 2019-06-06 | Zeno Royalties & Milestones Llc | Compuestos inhibidores de egfr. |
AU2019209475A1 (en) | 2018-01-16 | 2020-08-20 | Syros Pharmaceuticals, Inc. | Inhibitors of cyclin-dependent kinase 7 (CDK7) |
US11311542B2 (en) | 2018-01-16 | 2022-04-26 | Syros Pharmaceuticals, Inc. | Inhibitors of cyclin dependent kinase 7 (CDK7) |
AU2019374142A1 (en) | 2018-11-01 | 2021-05-27 | Syros Pharmaceuticals, Inc. | Methods of treating cancer in biomarker-identified patients with non-covalent inhibitors of cyclin-dependent kinase 7 (CDK7) |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1284728A4 (en) | 1999-10-22 | 2004-05-19 | Merck & Co Inc | MEDICINES FOR TREATING ADDICTIC ADDICTION |
CA2400021A1 (en) * | 2000-02-18 | 2001-08-23 | Merck & Co., Inc. | Aryloxyacetic acids for diabetes and lipid disorders |
JP2001354671A (ja) * | 2000-04-14 | 2001-12-25 | Nippon Chemiphar Co Ltd | ペルオキシソーム増殖剤応答性受容体δの活性化剤 |
ATE362468T1 (de) | 2000-07-25 | 2007-06-15 | Merck & Co Inc | N-substituierte indole mit anwendung in der behandlung von diabetes |
US6897231B2 (en) * | 2000-07-31 | 2005-05-24 | Signal Pharmaceuticals, Inc. | Indazole derivatives as JNK inhibitors and compositions and methods related thereto |
AU2002251978B2 (en) | 2001-02-09 | 2007-07-19 | Merck & Co., Inc. | 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders |
US7547710B2 (en) | 2002-08-08 | 2009-06-16 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compounds as peptidase inhibitors |
JP4542757B2 (ja) * | 2002-08-08 | 2010-09-15 | 武田薬品工業株式会社 | 縮合複素環化合物 |
US7393960B2 (en) * | 2002-08-29 | 2008-07-01 | Merck & Co., Inc. | Indoles having anti-diabetic activity |
ES2342596T3 (es) | 2002-08-29 | 2010-07-09 | MERCK SHARP & DOHME CORP. | Indoles con actividad anti-diabetica. |
CN101027056A (zh) | 2004-09-16 | 2007-08-29 | 默克公司 | 用于治疗血脂异常和其它脂质病症的化合物 |
-
2006
- 2006-03-03 WO PCT/US2006/007740 patent/WO2006096564A1/en active Application Filing
- 2006-03-03 MX MX2007010745A patent/MX2007010745A/es unknown
- 2006-03-03 US US11/884,802 patent/US7834036B2/en active Active
- 2006-03-03 RU RU2007136784/04A patent/RU2007136784A/ru not_active Application Discontinuation
- 2006-03-03 AU AU2006220809A patent/AU2006220809B2/en not_active Ceased
- 2006-03-03 EP EP06736976A patent/EP1861382B1/en active Active
- 2006-03-03 KR KR1020077020253A patent/KR20070110324A/ko not_active Application Discontinuation
- 2006-03-03 BR BRPI0609352-3A patent/BRPI0609352A2/pt not_active IP Right Cessation
- 2006-03-03 JP JP2007558289A patent/JP4638512B2/ja not_active Expired - Fee Related
- 2006-03-03 CN CN201110409206.6A patent/CN102584754B/zh not_active Expired - Fee Related
- 2006-03-03 CA CA2598725A patent/CA2598725C/en not_active Expired - Fee Related
- 2006-03-03 CN CNA2006800062459A patent/CN101128441A/zh active Pending
- 2006-03-03 ES ES06736976T patent/ES2393793T3/es active Active
-
2007
- 2007-08-01 ZA ZA200706394A patent/ZA200706394B/xx unknown
- 2007-08-08 NI NI200700200A patent/NI200700200A/es unknown
- 2007-08-20 IL IL185394A patent/IL185394A0/en unknown
- 2007-09-27 MA MA30253A patent/MA29352B1/fr unknown
- 2007-09-27 CR CR9401A patent/CR9401A/es unknown
- 2007-10-03 NO NO20075000A patent/NO20075000L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US7834036B2 (en) | 2010-11-16 |
BRPI0609352A2 (pt) | 2011-10-18 |
WO2006096564A1 (en) | 2006-09-14 |
ZA200706394B (en) | 2008-09-25 |
EP1861382B1 (en) | 2012-10-10 |
AU2006220809A1 (en) | 2006-09-14 |
JP2008531729A (ja) | 2008-08-14 |
EP1861382A1 (en) | 2007-12-05 |
CA2598725A1 (en) | 2006-09-14 |
CN102584754B (zh) | 2016-02-03 |
ES2393793T3 (es) | 2012-12-28 |
MX2007010745A (es) | 2007-09-12 |
JP4638512B2 (ja) | 2011-02-23 |
RU2007136784A (ru) | 2009-04-10 |
CN101128441A (zh) | 2008-02-20 |
CN102584754A (zh) | 2012-07-18 |
AU2006220809B2 (en) | 2009-06-11 |
US20080194586A1 (en) | 2008-08-14 |
KR20070110324A (ko) | 2007-11-16 |
NI200700200A (es) | 2008-02-29 |
IL185394A0 (en) | 2008-02-09 |
CA2598725C (en) | 2010-10-26 |
MA29352B1 (fr) | 2008-03-03 |
NO20075000L (no) | 2007-11-30 |
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