CR20130020A - Un nuevo conjugado de granulocito colonia-estimiulante factor (g-csf) con polietileno glicol - Google Patents
Un nuevo conjugado de granulocito colonia-estimiulante factor (g-csf) con polietileno glicolInfo
- Publication number
- CR20130020A CR20130020A CR20130020A CR20130020A CR20130020A CR 20130020 A CR20130020 A CR 20130020A CR 20130020 A CR20130020 A CR 20130020A CR 20130020 A CR20130020 A CR 20130020A CR 20130020 A CR20130020 A CR 20130020A
- Authority
- CR
- Costa Rica
- Prior art keywords
- csf
- stimulating factor
- new
- granulocit
- colonia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se relaciona a farmacéuticos y medicina, específicamente, a un nuevo conjugado fisiológicamente de granulocita colonia estimulante factor (G-CSF).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2010133875/10A RU2446173C1 (ru) | 2010-08-13 | 2010-08-13 | Новый функционально активный, высокоочищенный стабильный конъюгат гранулоцитарного колониестимулирующего фактора (г-ксф) с полиэтиленгликолем с пролонгированным биологическим действием, пригодный для медицинского применения, и иммунобиологическое средство на его основе |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20130020A true CR20130020A (es) | 2013-02-20 |
Family
ID=45567857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20130020A CR20130020A (es) | 2010-08-13 | 2013-01-18 | Un nuevo conjugado de granulocito colonia-estimiulante factor (g-csf) con polietileno glicol |
Country Status (17)
Country | Link |
---|---|
KR (1) | KR101549457B1 (es) |
CN (1) | CN103140499B (es) |
CL (1) | CL2013000400A1 (es) |
CO (1) | CO6670557A2 (es) |
CR (1) | CR20130020A (es) |
CU (1) | CU24139B1 (es) |
DO (1) | DOP2013000003A (es) |
EA (1) | EA019043B1 (es) |
EC (1) | ECSP13012399A (es) |
MA (1) | MA34525B1 (es) |
MY (1) | MY160732A (es) |
NI (1) | NI201300007A (es) |
PE (1) | PE20131085A1 (es) |
RS (1) | RS20130094A1 (es) |
RU (1) | RU2446173C1 (es) |
SG (1) | SG187572A1 (es) |
WO (1) | WO2012021088A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012110057A1 (en) | 2011-02-15 | 2012-08-23 | Chemisches Institut Schaefer Ag | Cefuroxime safety kit |
NZ702415A (en) | 2012-06-07 | 2016-04-29 | Children’S Hospital Los Angeles | Methods for treating neutropenia using retinoid agonists |
CN103908427B (zh) * | 2013-01-05 | 2014-12-17 | 石药集团百克(山东)生物制药有限公司 | 一种聚乙二醇修饰的rhG-CSF注射液及其制备方法 |
RU2535002C2 (ru) * | 2013-04-04 | 2014-12-10 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт фармакологии" Сибирского отделения Российской академии медицинских наук | Средство коррекции отдаленных последствий нарушений сперматогенеза, вызванных цитостатическим воздействием |
RU2016136833A (ru) | 2014-02-18 | 2018-03-22 | Чилдрен'З Хоспитал Лос Анджелес | Композиции и способы для лечения нейтропении |
AU2015291123C1 (en) | 2014-07-14 | 2020-12-10 | Gennova Biopharmaceuticals Limited | A novel process for purification of rHu-GCSF |
IL247369B (en) * | 2016-08-18 | 2018-08-30 | B G Negev Tech And Applications Ltd | Polypeptides derived from CSF-m and their uses |
KR102020995B1 (ko) * | 2017-10-30 | 2019-09-16 | 한국코러스 주식회사 | 콜로니자극인자와 폴리올이 접합된 접합물을 고수율로 제조하는 방법 |
BR112022018501A2 (pt) * | 2020-03-17 | 2022-10-25 | Drugrecure Aps | Formulação líquida de gm-csf para inalação |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2006596C (en) * | 1988-12-22 | 2000-09-05 | Rika Ishikawa | Chemically-modified g-csf |
US5252714A (en) * | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
US5824784A (en) * | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
KR20040083268A (ko) * | 2003-03-21 | 2004-10-01 | 한미약품 주식회사 | 안정성이 증가된 인간 과립구 콜로니 자극인자 융합체 및이의 제조방법 |
RU2278870C2 (ru) * | 2004-08-30 | 2006-06-27 | Закрытое Акционерное Общество "Биокад" | Способ получения, выделения, очистки и стабилизации рекомбинантного гранулоцитарного колониестимулирующего фактора человека, пригодного для медицинского применения, и иммунобиологическое средство на его основе |
ES2397712T3 (es) * | 2006-01-18 | 2013-03-08 | Qps, Llc | Composiciones farmacéuticas con estabilidad reforzada |
US8840882B2 (en) * | 2006-06-23 | 2014-09-23 | Quintessence Biosciences, Inc. | Modified ribonucleases |
-
2010
- 2010-08-13 RU RU2010133875/10A patent/RU2446173C1/ru active
-
2011
- 2011-07-19 KR KR1020137001860A patent/KR101549457B1/ko not_active IP Right Cessation
- 2011-07-19 MY MYPI2013000217A patent/MY160732A/en unknown
- 2011-07-19 CN CN201180044089.6A patent/CN103140499B/zh not_active Expired - Fee Related
- 2011-07-19 WO PCT/RU2011/000532 patent/WO2012021088A1/en active Application Filing
- 2011-07-19 SG SG2013004544A patent/SG187572A1/en unknown
- 2011-07-19 RS RS20130094A patent/RS20130094A1/en unknown
- 2011-07-19 CU CU20130012A patent/CU24139B1/es unknown
- 2011-07-19 PE PE2013000083A patent/PE20131085A1/es not_active Application Discontinuation
- 2011-07-19 MA MA35731A patent/MA34525B1/fr unknown
- 2011-08-01 EA EA201101035A patent/EA019043B1/ru not_active IP Right Cessation
-
2013
- 2013-01-04 DO DO2013000003A patent/DOP2013000003A/es unknown
- 2013-01-18 CR CR20130020A patent/CR20130020A/es unknown
- 2013-01-18 CO CO13009151A patent/CO6670557A2/es unknown
- 2013-01-18 NI NI201300007A patent/NI201300007A/es unknown
- 2013-01-18 EC ECSP13012399 patent/ECSP13012399A/es unknown
- 2013-02-08 CL CL2013000400A patent/CL2013000400A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO2012021088A1 (en) | 2012-02-16 |
CO6670557A2 (es) | 2013-05-15 |
PE20131085A1 (es) | 2013-10-10 |
SG187572A1 (en) | 2013-03-28 |
CU24139B1 (es) | 2015-12-23 |
EA201101035A1 (ru) | 2012-02-28 |
CN103140499A (zh) | 2013-06-05 |
NI201300007A (es) | 2014-05-26 |
KR101549457B1 (ko) | 2015-09-02 |
MY160732A (en) | 2017-03-15 |
CN103140499B (zh) | 2014-12-17 |
MA34525B1 (fr) | 2013-09-02 |
ECSP13012399A (es) | 2013-05-31 |
CU20130012A7 (es) | 2013-04-19 |
DOP2013000003A (es) | 2013-07-31 |
RU2446173C1 (ru) | 2012-03-27 |
EA019043B1 (ru) | 2013-12-30 |
RS20130094A1 (en) | 2013-08-30 |
KR20130043167A (ko) | 2013-04-29 |
CL2013000400A1 (es) | 2013-07-26 |
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