CR11432A - Acidos carboxilicos bifenil y derivados de los mismos - Google Patents

Acidos carboxilicos bifenil y derivados de los mismos

Info

Publication number
CR11432A
CR11432A CR11432A CR11432A CR11432A CR 11432 A CR11432 A CR 11432A CR 11432 A CR11432 A CR 11432A CR 11432 A CR11432 A CR 11432A CR 11432 A CR11432 A CR 11432A
Authority
CR
Costa Rica
Prior art keywords
bifenil
derivatives
same
carboxilic acids
carboxilic
Prior art date
Application number
CR11432A
Other languages
English (en)
Inventor
Yung Ho Chih
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CR11432A publication Critical patent/CR11432A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

La presente invencion se refiere a compuestos que tienen la formula general (I) con las definiciones R1, R2, R3, Y R4 dadas a continuacion y/o una sal o ester de estos.
CR11432A 2007-10-17 2010-05-17 Acidos carboxilicos bifenil y derivados de los mismos CR11432A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98058707P 2007-10-17 2007-10-17

Publications (1)

Publication Number Publication Date
CR11432A true CR11432A (es) 2010-10-14

Family

ID=40345060

Family Applications (1)

Application Number Title Priority Date Filing Date
CR11432A CR11432A (es) 2007-10-17 2010-05-17 Acidos carboxilicos bifenil y derivados de los mismos

Country Status (18)

Country Link
US (1) US7897643B2 (es)
EP (1) EP2215044B8 (es)
JP (1) JP5404634B2 (es)
KR (1) KR101579744B1 (es)
CN (1) CN101861297B (es)
AU (1) AU2008312771B2 (es)
BR (1) BRPI0817424A2 (es)
CA (1) CA2702832A1 (es)
CO (1) CO6270313A2 (es)
CR (1) CR11432A (es)
DK (1) DK2215044T3 (es)
EA (1) EA017616B1 (es)
ES (1) ES2395083T3 (es)
IL (1) IL205047A (es)
MX (1) MX2010004261A (es)
NI (1) NI201000058A (es)
WO (1) WO2009051948A1 (es)
ZA (1) ZA201003432B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101903335A (zh) * 2007-10-19 2010-12-01 詹森药业有限公司 连接有胺的γ-分泌酶调节剂
MX2010004309A (es) * 2007-10-19 2010-05-03 Janssen Pharmaceutica Nv Moduladores de piperidinil y piperazinil de gamma-secretasa.
EP2215043B1 (en) * 2007-10-19 2013-03-06 Janssen Pharmaceutica, N.V. Carbon linked modulators of y-secretase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877399A (en) 1994-01-27 1999-03-02 Johns Hopkins University Transgenic mice expressing APP-Swedish mutation develop progressive neurologic disease
EP1284729A4 (en) 2000-04-13 2007-12-19 Mayo Foundation REDUCTION AGENTS OF A (BETA) 42
DE10131899A1 (de) 2001-07-04 2003-02-27 Boehringer Ingelheim Pharma In vitro-Screening-Assay für gamma-Secretase
WO2006004555A1 (en) 2004-06-30 2006-01-12 Paysetter Pte Ltd System and method for facilitating transfer of physical money and/or credit
DE102004033876B4 (de) 2004-07-13 2009-01-15 Christoph Kaesbohrer Dreidimensionales Struktursystem
EP1650183A1 (en) 2004-10-21 2006-04-26 Cellzome Ag (Benzyloxy-biphenyl) acetic acids and derivatives thereof and their use in therapy

Also Published As

Publication number Publication date
EP2215044B1 (en) 2012-08-29
JP2011500691A (ja) 2011-01-06
ES2395083T3 (es) 2013-02-08
CA2702832A1 (en) 2009-04-23
CO6270313A2 (es) 2011-04-20
ZA201003432B (en) 2012-07-25
EP2215044A1 (en) 2010-08-11
US20090105344A1 (en) 2009-04-23
EA017616B1 (ru) 2013-01-30
NI201000058A (es) 2010-09-13
AU2008312771B2 (en) 2012-11-01
KR101579744B1 (ko) 2015-12-23
IL205047A (en) 2014-09-30
BRPI0817424A2 (pt) 2015-06-16
US7897643B2 (en) 2011-03-01
EA201070478A1 (ru) 2010-10-29
ES2395083T8 (es) 2014-11-17
JP5404634B2 (ja) 2014-02-05
KR20100090264A (ko) 2010-08-13
IL205047A0 (en) 2010-11-30
CN101861297B (zh) 2014-04-23
AU2008312771A1 (en) 2009-04-23
DK2215044T3 (da) 2012-11-26
CN101861297A (zh) 2010-10-13
MX2010004261A (es) 2010-04-30
WO2009051948A1 (en) 2009-04-23
EP2215044B8 (en) 2012-10-03

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)