CO6470857A2 - Lipopolisacárido de ochrobactrum intermedium y su uso como inmunoestimulante en mamiferos - Google Patents
Lipopolisacárido de ochrobactrum intermedium y su uso como inmunoestimulante en mamiferosInfo
- Publication number
- CO6470857A2 CO6470857A2 CO11166480A CO11166480A CO6470857A2 CO 6470857 A2 CO6470857 A2 CO 6470857A2 CO 11166480 A CO11166480 A CO 11166480A CO 11166480 A CO11166480 A CO 11166480A CO 6470857 A2 CO6470857 A2 CO 6470857A2
- Authority
- CO
- Colombia
- Prior art keywords
- immunostimulant
- lipopolisacárido
- mammals
- ochrobactrum intermedium
- ochrobactrum
- Prior art date
Links
- 241000359249 Ochrobactrum intermedium Species 0.000 title abstract 2
- 229960001438 immunostimulant agent Drugs 0.000 title abstract 2
- 239000003022 immunostimulating agent Substances 0.000 title abstract 2
- 230000003308 immunostimulating effect Effects 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title 1
- 239000002158 endotoxin Substances 0.000 abstract 2
- 229920006008 lipopolysaccharide Polymers 0.000 abstract 2
- 208000004554 Leishmaniasis Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 206010040047 Sepsis Diseases 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/739—Lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere al aislamiento, purificación y caracterización del lipopolisacárido (LPS) de la cepa Ochrobactrum Intermedium LMG3306, y su uso como inmunoestimulante de mamíferos, el procedimiento para la preparación de un compuesto farmacéutico para el tratamiento y)o la prevención de la sepsis y adyuvante para una vacuna en animales inmunodeprimidos y contra la Leishmaniosis.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200930265A ES2352780B2 (es) | 2009-06-04 | 2009-06-04 | Lipopolisacárido de ochrobactrum intermedium contra la sepsis. |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6470857A2 true CO6470857A2 (es) | 2012-06-29 |
Family
ID=41796455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO11166480A CO6470857A2 (es) | 2009-06-04 | 2011-12-02 | Lipopolisacárido de ochrobactrum intermedium y su uso como inmunoestimulante en mamiferos |
Country Status (20)
Country | Link |
---|---|
US (1) | US9241954B2 (es) |
EP (1) | EP2437754B1 (es) |
JP (1) | JP5730862B2 (es) |
KR (1) | KR20120061045A (es) |
CN (1) | CN102802639A (es) |
AU (1) | AU2009347459A1 (es) |
BR (1) | BRPI0924393A2 (es) |
CA (1) | CA2763266A1 (es) |
CL (1) | CL2011003033A1 (es) |
CO (1) | CO6470857A2 (es) |
CU (1) | CU24041B1 (es) |
EA (1) | EA025766B1 (es) |
ES (2) | ES2352780B2 (es) |
IL (1) | IL216560A0 (es) |
MX (1) | MX2011012934A (es) |
NZ (1) | NZ596599A (es) |
PL (1) | PL2437754T3 (es) |
SG (1) | SG176660A1 (es) |
WO (1) | WO2010139352A1 (es) |
ZA (1) | ZA201200021B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103937722B (zh) * | 2014-04-24 | 2016-10-26 | 烟台地元生物科技有限公司 | 中间苍白杆菌及微生物菌剂和它们的应用 |
CN106754562B (zh) * | 2017-02-14 | 2020-06-02 | 南京中医药大学 | 一种高产细菌多糖的菌株及其发酵中药废弃物制备多糖的方法 |
CN106755186B (zh) * | 2017-02-14 | 2020-03-31 | 南京中医药大学 | 一种中间苍白杆菌胞外多糖及其在土壤改良方面的应用 |
CN109182159B (zh) * | 2018-07-27 | 2021-04-23 | 华南农业大学 | 一种n-酰基高丝氨酸内酯淬灭菌及其在病害防控中的应用 |
MA55805A (fr) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | Métodes de modulation de l'activité immunitaire |
CN111053789A (zh) * | 2019-11-26 | 2020-04-24 | 湖南营养树生物科技有限公司 | 调节免疫系统的方法和组合物 |
RU2736933C1 (ru) * | 2020-05-20 | 2020-11-23 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт эпидемиологии и микробиологии имени Г.П. Сомова" (НИИ эпидемиологии и микробиологии имени Г.П. Сомова) | Адъювант |
CN111909874B (zh) * | 2020-08-17 | 2022-08-19 | 东北农业大学 | 一株生防菌i-5及其在防治紫花苜蓿根腐病中的应用 |
CN112625943B (zh) * | 2020-12-02 | 2021-11-16 | 安徽农业大学 | 一种玉米用溶钾菌剂及其制备方法和应用 |
CA3208643A1 (en) | 2021-01-18 | 2022-07-21 | Conserv Bioscience Limited | Coronavirus immunogenic compositions, methods and uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5824310A (en) * | 1991-10-22 | 1998-10-20 | The United States Of America As Represented By The Department Of Health And Human Services | Lipopplysaccharide conjugate vaccines |
GB9706930D0 (en) | 1997-04-04 | 1997-05-21 | Univ Glasgow | Leishmania vaccine |
EP1322655B1 (en) | 2000-01-14 | 2007-11-14 | The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services | Oligodeoxynucleotide and its use to induce an immune response |
WO2009012166A1 (en) * | 2007-07-13 | 2009-01-22 | Infectious Disease Research Institute | Leishmania sterol 24-c-methyltransferase compositions for the prevention, treatment and diagnosis of leishmaniasis |
-
2009
- 2009-06-04 ES ES200930265A patent/ES2352780B2/es active Active
- 2009-12-31 NZ NZ596599A patent/NZ596599A/xx not_active IP Right Cessation
- 2009-12-31 EP EP09799043.6A patent/EP2437754B1/en active Active
- 2009-12-31 AU AU2009347459A patent/AU2009347459A1/en not_active Abandoned
- 2009-12-31 EA EA201190309A patent/EA025766B1/ru not_active IP Right Cessation
- 2009-12-31 ES ES09799043.6T patent/ES2653202T3/es active Active
- 2009-12-31 CA CA2763266A patent/CA2763266A1/en not_active Abandoned
- 2009-12-31 WO PCT/EP2009/009342 patent/WO2010139352A1/en active Application Filing
- 2009-12-31 JP JP2012513476A patent/JP5730862B2/ja not_active Expired - Fee Related
- 2009-12-31 KR KR1020127000276A patent/KR20120061045A/ko not_active Application Discontinuation
- 2009-12-31 PL PL09799043T patent/PL2437754T3/pl unknown
- 2009-12-31 CN CN2009801603018A patent/CN102802639A/zh active Pending
- 2009-12-31 US US13/375,174 patent/US9241954B2/en active Active
- 2009-12-31 MX MX2011012934A patent/MX2011012934A/es unknown
- 2009-12-31 SG SG2011089620A patent/SG176660A1/en unknown
- 2009-12-31 BR BRPI0924393A patent/BRPI0924393A2/pt active Search and Examination
-
2011
- 2011-11-23 IL IL216560A patent/IL216560A0/en unknown
- 2011-12-01 CL CL2011003033A patent/CL2011003033A1/es unknown
- 2011-12-02 CO CO11166480A patent/CO6470857A2/es active IP Right Grant
- 2011-12-02 CU CU2011000223A patent/CU24041B1/es active IP Right Grant
-
2012
- 2012-01-03 ZA ZA2012/00021A patent/ZA201200021B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN102802639A (zh) | 2012-11-28 |
CU24041B1 (es) | 2014-11-27 |
ES2352780A1 (es) | 2011-02-23 |
CL2011003033A1 (es) | 2012-07-06 |
ES2653202T3 (es) | 2018-02-06 |
EP2437754B1 (en) | 2017-09-20 |
CU20110223A7 (es) | 2012-06-21 |
JP5730862B2 (ja) | 2015-06-10 |
SG176660A1 (en) | 2012-01-30 |
KR20120061045A (ko) | 2012-06-12 |
MX2011012934A (es) | 2012-04-30 |
ZA201200021B (en) | 2013-03-27 |
EA025766B1 (ru) | 2017-01-30 |
US9241954B2 (en) | 2016-01-26 |
AU2009347459A1 (en) | 2011-12-22 |
BRPI0924393A2 (pt) | 2016-09-06 |
WO2010139352A1 (en) | 2010-12-09 |
JP2012528805A (ja) | 2012-11-15 |
US20120107352A1 (en) | 2012-05-03 |
CA2763266A1 (en) | 2010-12-09 |
NZ596599A (en) | 2013-08-30 |
ES2352780B2 (es) | 2011-09-15 |
IL216560A0 (en) | 2012-02-29 |
EA201190309A1 (ru) | 2012-05-30 |
PL2437754T3 (pl) | 2018-03-30 |
EP2437754A1 (en) | 2012-04-11 |
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Legal Events
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