AR079341A1 - Octadepsipeptidos ciclicos a partir de cepas fungicas y su uso como antihelminticos o endoparasiticidas - Google Patents
Octadepsipeptidos ciclicos a partir de cepas fungicas y su uso como antihelminticos o endoparasiticidasInfo
- Publication number
- AR079341A1 AR079341A1 ARP100104550A ARP100104550A AR079341A1 AR 079341 A1 AR079341 A1 AR 079341A1 AR P100104550 A ARP100104550 A AR P100104550A AR P100104550 A ARP100104550 A AR P100104550A AR 079341 A1 AR079341 A1 AR 079341A1
- Authority
- AR
- Argentina
- Prior art keywords
- xrb
- octadepsypeptides
- cyclic
- endoparasiticides
- mentioned above
- Prior art date
Links
- 239000000921 anthelmintic agent Substances 0.000 title abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 4
- 230000002538 fungal effect Effects 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 2
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 abstract 1
- 239000004377 Alitame Substances 0.000 abstract 1
- QVZZPLDJERFENQ-UHFFFAOYSA-N Bassianolide Natural products CC(C)CC1N(C)C(=O)C(C(C)C)OC(=O)C(CC(C)C)N(C)C(=O)C(C(C)C)OC(=O)C(CC(C)C)N(C)C(=O)C(C(C)C)OC(=O)C(CC(C)C)N(C)C(=O)C(C(C)C)OC1=O QVZZPLDJERFENQ-UHFFFAOYSA-N 0.000 abstract 1
- 241000223679 Beauveria Species 0.000 abstract 1
- 241001183555 Coniolariella Species 0.000 abstract 1
- 241000223218 Fusarium Species 0.000 abstract 1
- 241000221775 Hypocreales Species 0.000 abstract 1
- 241000221919 Phyllachorales Species 0.000 abstract 1
- 239000004153 Potassium bromate Substances 0.000 abstract 1
- 239000004159 Potassium persulphate Substances 0.000 abstract 1
- 241001299709 Rosellinia Species 0.000 abstract 1
- 241000082085 Verticillium <Phyllachorales> Species 0.000 abstract 1
- 241001523964 Xylariaceae Species 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 229940124339 anthelmintic agent Drugs 0.000 abstract 1
- QVZZPLDJERFENQ-NKTUOASPSA-N bassianolide Chemical compound CC(C)C[C@@H]1N(C)C(=O)[C@@H](C(C)C)OC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C(C)C)OC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C(C)C)OC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C(C)C)OC1=O QVZZPLDJERFENQ-NKTUOASPSA-N 0.000 abstract 1
- 108010076663 bassianolide Proteins 0.000 abstract 1
- 229940079919 digestives enzyme preparation Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Octadepsipéptidos cíclicos de 24 miembros PF1022-V, PF1022-W, XRB-C894, XRB-C942, XRB-C976, XRB-C1010, XRB-C1044, XRB-E922, XRB-E956, XRB-E990, XRB-E1024, XRB-S958, XRB-S992, XRB-S1026, XRB-S1060 (en varias formas isoméricas) y a los procedimientos para la preparacion de los octadepsipéptidos cíclicos mencionados anteriormente por medio de las cepas fungicas de la familia Xylariaceae, en particular de los géneros Rosellinia y Coniolariella, y por medio de las cepas fungicas mitosporicas de los grupos Fusarium, Beauveria y Verticillium (ordenes Hypocreales y Phyllachorales), y por medio de las preparaciones enzimáticas aisladas a partir de esas cepas fungicas, y en segundo lugar al uso de estas cepas para la preparacion de los octadepsipéptidos cíclicos mencionados anteriormente y al uso de bassianolida y de los octadepsipéptidos cíclicos mencionados anteriormente, de manera individual o como una mezcla, como antihelmínticos o endoparasiticidas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09178799 | 2009-12-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR079341A1 true AR079341A1 (es) | 2012-01-18 |
Family
ID=43480707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100104550A AR079341A1 (es) | 2009-12-11 | 2010-12-09 | Octadepsipeptidos ciclicos a partir de cepas fungicas y su uso como antihelminticos o endoparasiticidas |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120302496A1 (es) |
| EP (1) | EP2509967B1 (es) |
| JP (1) | JP5779787B2 (es) |
| AR (1) | AR079341A1 (es) |
| AU (1) | AU2010329998B2 (es) |
| TW (1) | TW201138799A (es) |
| UY (1) | UY33095A (es) |
| WO (1) | WO2011069995A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE042661T2 (hu) | 2012-06-13 | 2019-07-29 | Meiji Seika Pharma Co Ltd | Új ciklusos depszipeptid származék és ezt tartalmazó kártevõirtó szer |
| WO2015093558A1 (ja) * | 2013-12-18 | 2015-06-25 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 環状デプシペプチド誘導体およびそれを含んでなる有害生物防除剤 |
| CN114891070A (zh) | 2015-05-20 | 2022-08-12 | 勃林格殷格翰动物保健美国公司 | 驱虫缩酚酸肽化合物 |
| KR20220003663A (ko) | 2015-12-28 | 2022-01-10 | 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 | 구충성 뎁시펩티드 화합물 |
| MX2019005628A (es) | 2016-11-16 | 2019-12-18 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos depsipeptidos antihelminticos. |
| CN106749569B (zh) * | 2017-03-03 | 2021-10-15 | 重庆乾泰生物医药有限公司 | 一种pf1022a的分离纯化方法 |
| CN106978353B (zh) * | 2017-03-10 | 2019-10-18 | 广东省微生物研究所 | 特氏炭角菌及其栽培方法 |
| CN108570016B (zh) * | 2017-03-10 | 2021-11-26 | 上海医药工业研究院 | 一种pf1022a分离纯化的方法 |
| CN113943350B (zh) * | 2021-11-02 | 2023-08-15 | 海南大学三亚南繁研究院 | 一种环肽化合物或其药学上可接受的盐及其制备方法和应用、药物及其应用 |
| CN114875093B (zh) * | 2022-05-20 | 2024-07-19 | 浙江海正药业股份有限公司 | 一种提高pf1022a发酵产量的方法 |
| WO2025149943A1 (en) * | 2024-01-09 | 2025-07-17 | Animol Discovery, Inc. | Antiparasitic cyclic depsipeptides |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO176766C (no) * | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
| JP3207870B2 (ja) * | 1991-04-15 | 2001-09-10 | 明治製菓株式会社 | 環状デプシペプチドおよびその製造法 |
| JP2873894B2 (ja) * | 1992-10-19 | 1999-03-24 | 明治製菓株式会社 | 環状デプシペプチドおよびその製造法 |
| DE4317432A1 (de) * | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| DE4341992A1 (de) | 1993-12-09 | 1995-06-14 | Bayer Ag | Endoparasitizide Mittel auf Basis von offenkettigen Tetradepsipeptiden |
| NZ334073A (en) | 1996-08-07 | 2000-10-27 | Meiji Seika Kaisha | Process for producing cyclodepsipeptide compounds |
| US20110262969A1 (en) * | 2008-12-16 | 2011-10-27 | Achim Harder | Method for producing optically active, cyclic depsipeptides comprising lactic acid and phenyl lactic and having 24 ring atoms, using fungus strains of rosellinia type, and further species of xylariaceae |
| WO2010107232A2 (en) | 2009-03-16 | 2010-09-23 | Lg Electronics Inc. | Method of retransmission for supporting mimo in synchronous harq |
-
2010
- 2010-12-07 JP JP2012542507A patent/JP5779787B2/ja not_active Expired - Fee Related
- 2010-12-07 WO PCT/EP2010/069040 patent/WO2011069995A1/en not_active Ceased
- 2010-12-07 US US13/514,538 patent/US20120302496A1/en not_active Abandoned
- 2010-12-07 EP EP10790400.5A patent/EP2509967B1/en not_active Not-in-force
- 2010-12-07 AU AU2010329998A patent/AU2010329998B2/en not_active Ceased
- 2010-12-08 UY UY33095A patent/UY33095A/es not_active Application Discontinuation
- 2010-12-09 AR ARP100104550A patent/AR079341A1/es unknown
- 2010-12-10 TW TW099143150A patent/TW201138799A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010329998A1 (en) | 2012-07-05 |
| UY33095A (es) | 2011-07-29 |
| TW201138799A (en) | 2011-11-16 |
| JP5779787B2 (ja) | 2015-09-16 |
| WO2011069995A1 (en) | 2011-06-16 |
| EP2509967B1 (en) | 2016-02-17 |
| US20120302496A1 (en) | 2012-11-29 |
| JP2013513567A (ja) | 2013-04-22 |
| EP2509967A1 (en) | 2012-10-17 |
| AU2010329998B2 (en) | 2015-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |