CO6450678A2 - Proceso para preparar compuestos antivirales - Google Patents

Proceso para preparar compuestos antivirales

Info

Publication number
CO6450678A2
CO6450678A2 CO11123197A CO11123197A CO6450678A2 CO 6450678 A2 CO6450678 A2 CO 6450678A2 CO 11123197 A CO11123197 A CO 11123197A CO 11123197 A CO11123197 A CO 11123197A CO 6450678 A2 CO6450678 A2 CO 6450678A2
Authority
CO
Colombia
Prior art keywords
antiviral compounds
salts
compound
prepare antiviral
prepare
Prior art date
Application number
CO11123197A
Other languages
English (en)
Inventor
James J Napier
Calvin L Becker
Jean Christophe Califano
Su Yu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of CO6450678A2 publication Critical patent/CO6450678A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Abstract

(a) Procesos para preparar un compuesto y sales del mismo que, entre otros, son de utilidad para inhibir al virus de la hepatitis C (HCV); (b) intermediarios de utilidad para la preparación del compuesto y las sales; (c) composiciones farmacéuticas que comprenden al compuesto o las sales; y (d) métodos para usar de dichas composiciones.
CO11123197A 2009-03-24 2011-09-21 Proceso para preparar compuestos antivirales CO6450678A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16270509P 2009-03-24 2009-03-24
US31671310P 2010-03-23 2010-03-23

Publications (1)

Publication Number Publication Date
CO6450678A2 true CO6450678A2 (es) 2012-05-31

Family

ID=42136100

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11123197A CO6450678A2 (es) 2009-03-24 2011-09-21 Proceso para preparar compuestos antivirales

Country Status (24)

Country Link
EP (1) EP2411372B1 (es)
JP (1) JP5744003B2 (es)
KR (1) KR101665955B1 (es)
CN (1) CN102361858B (es)
AU (1) AU2010229975B2 (es)
BR (1) BRPI1009854A2 (es)
CA (1) CA2753825C (es)
CL (1) CL2011002278A1 (es)
CO (1) CO6450678A2 (es)
CR (1) CR20110524A (es)
DO (1) DOP2011000297A (es)
EC (1) ECSP11011415A (es)
ES (1) ES2488821T3 (es)
GT (1) GT201100241A (es)
HK (1) HK1166798A1 (es)
IL (1) IL214858A (es)
MX (1) MX2011010049A (es)
MY (1) MY169288A (es)
NZ (1) NZ594923A (es)
PE (1) PE20120519A1 (es)
RU (1) RU2524573C2 (es)
SG (1) SG174211A1 (es)
WO (1) WO2010111348A1 (es)
ZA (1) ZA201106511B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9255074B2 (en) 2010-07-16 2016-02-09 Abbvie Inc. Process for preparing antiviral compounds
MY167881A (en) 2010-07-16 2018-09-26 Abbvie Bahamas Ltd Process for preparing antiviral compounds
MX338725B (es) 2010-07-16 2016-04-28 Abbvie Bahamas Ltd Ligando de fosfina para reacciones cataliticas.
US8975443B2 (en) 2010-07-16 2015-03-10 Abbvie Inc. Phosphine ligands for catalytic reactions
CA2829768A1 (en) * 2011-03-18 2012-09-27 Abbvie Inc. Formulations of phenyl uracil compounds
US20160375017A1 (en) 2015-06-26 2016-12-29 Abbvie Inc. Solid Pharmaceutical Compositions for Treating HCV

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1219626B1 (en) * 1999-09-20 2005-06-01 Fuji Photo Film Co., Ltd. Compounds for fluorescence labeling
DK1218401T3 (da) * 1999-09-22 2004-10-04 Aventis Pharma Gmbh 4-Benzylaminoquinolin-konjugat med galdesyre og deres heteroanaloger, fremgangsmåde til deres fremstilling, lægemidler indeholdende disse forbindelser og deres anvendelse
DE10051981A1 (de) * 2000-10-20 2002-05-02 Bayer Ag Substituierte Phenyluracile
AU2007266915A1 (en) 2006-05-30 2007-12-06 Arrow Therapeutics Limited Biphenyl derivatives and their use in treating hepatitis C
EP2548873A1 (en) * 2007-09-17 2013-01-23 Abbott Laboratories N-phenyl-dioxo-hydropyrimidines useful as hepatitis c virus (hcv) inhibitors
WO2009039127A1 (en) * 2007-09-17 2009-03-26 Abbott Laboratories Uracil or thymine derivative for treating hepatitis c
JP2011528686A (ja) * 2008-07-23 2011-11-24 エフ．ホフマン−ラ ロシュ アーゲー ヘテロ環式抗ウイルス性化合物

Also Published As

Publication number Publication date
IL214858A0 (en) 2011-11-30
CL2011002278A1 (es) 2012-03-09
CR20110524A (es) 2012-01-19
JP2012521990A (ja) 2012-09-20
EP2411372A1 (en) 2012-02-01
RU2011142757A (ru) 2013-04-27
CN102361858B (zh) 2014-07-23
EP2411372B1 (en) 2014-07-23
JP5744003B2 (ja) 2015-07-01
NZ594923A (en) 2013-11-29
AU2010229975A1 (en) 2011-09-29
DOP2011000297A (es) 2011-10-15
KR20110137372A (ko) 2011-12-22
CA2753825C (en) 2017-10-17
GT201100241A (es) 2015-08-19
CN102361858A (zh) 2012-02-22
RU2524573C2 (ru) 2014-07-27
KR101665955B1 (ko) 2016-10-13
IL214858A (en) 2015-05-31
MY169288A (en) 2019-03-21
AU2010229975B2 (en) 2015-05-21
BRPI1009854A2 (pt) 2015-08-25
ES2488821T3 (es) 2014-08-29
ECSP11011415A (es) 2011-11-30
WO2010111348A1 (en) 2010-09-30
HK1166798A1 (en) 2012-11-09
ZA201106511B (en) 2012-05-30
PE20120519A1 (es) 2012-06-03
MX2011010049A (es) 2011-10-11
CA2753825A1 (en) 2010-09-30
SG174211A1 (en) 2011-10-28

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Legal Events

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