CO6351719A2 - Metodos para administrar formulaciones antifúngicas tópicas para el tratamiento de infecciones fúngicas - Google Patents
Metodos para administrar formulaciones antifúngicas tópicas para el tratamiento de infecciones fúngicasInfo
- Publication number
- CO6351719A2 CO6351719A2 CO11017742A CO11017742A CO6351719A2 CO 6351719 A2 CO6351719 A2 CO 6351719A2 CO 11017742 A CO11017742 A CO 11017742A CO 11017742 A CO11017742 A CO 11017742A CO 6351719 A2 CO6351719 A2 CO 6351719A2
- Authority
- CO
- Colombia
- Prior art keywords
- formula
- group
- alkyl
- lower alkyl
- hydrogen
- Prior art date
Links
- 206010017533 Fungal infection Diseases 0.000 title 1
- 208000031888 Mycoses Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 7
- 239000001257 hydrogen Substances 0.000 abstract 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000005277 alkyl imino group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8311508P | 2008-07-23 | 2008-07-23 | |
| US10211108P | 2008-10-02 | 2008-10-02 | |
| US15018709P | 2009-02-05 | 2009-02-05 | |
| US16812209P | 2009-04-09 | 2009-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6351719A2 true CO6351719A2 (es) | 2011-12-20 |
Family
ID=41358304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO11017742A CO6351719A2 (es) | 2008-07-23 | 2011-02-15 | Metodos para administrar formulaciones antifúngicas tópicas para el tratamiento de infecciones fúngicas |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20100086504A1 (enExample) |
| EP (1) | EP2317993A2 (enExample) |
| JP (1) | JP2011529038A (enExample) |
| KR (1) | KR20110039357A (enExample) |
| CN (1) | CN102159202A (enExample) |
| AU (1) | AU2009275230A1 (enExample) |
| CA (1) | CA2731455A1 (enExample) |
| CL (1) | CL2011000135A1 (enExample) |
| CO (1) | CO6351719A2 (enExample) |
| EC (1) | ECSP11010818A (enExample) |
| IL (1) | IL210813A0 (enExample) |
| MX (1) | MX2011000932A (enExample) |
| NI (1) | NI201100025A (enExample) |
| PE (1) | PE20110642A1 (enExample) |
| WO (1) | WO2010010470A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101652124A (zh) | 2007-02-05 | 2010-02-17 | 亲生物有限公司 | 烯丙胺药物化合物的增加的效力 |
| MX2011008204A (es) * | 2009-02-05 | 2011-12-06 | Targeted Delivery Technologies Ltd | Metodos para reducir la proliferacion y viabilidad de los agentes microbianos. |
| FR2954163B1 (fr) * | 2009-12-18 | 2012-03-16 | Galderma Pharma Sa | Utilisation d'un tensioactif cationique, avantageu-sement amphotere, pour la preparation d'une composition antifongique applicable sur l'ongle |
| WO2011079234A2 (en) | 2009-12-23 | 2011-06-30 | Nuvo Research Inc. | Highly permeating terbinafine formulation |
| RU2587064C2 (ru) * | 2011-02-11 | 2016-06-10 | Моберг Фарма Аб | Новая противогрибковая композиция |
| DE112012001386T5 (de) * | 2011-03-21 | 2013-12-19 | Gregor Cevc | Optimierte Präparate von sehr anpassungsfähigen Aggregaten |
| WO2013057208A1 (en) | 2011-10-18 | 2013-04-25 | Targeted Delivery Technologies Limited | Compositions and methods for reducing the proliferation and viability of microbial agents |
| US8697753B1 (en) * | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
| US11135456B2 (en) | 2014-03-14 | 2021-10-05 | Gojo Industries, Inc. | Hand sanitizers with improved aesthetics and skin-conditioning to encourage compliance with hand hygiene guidelines |
| AT516544B1 (de) | 2014-12-02 | 2017-05-15 | Universität Innsbruck | Stoffgemisch und Zubereitung |
| CN105193726B (zh) * | 2015-11-08 | 2018-01-26 | 长沙佰顺生物科技有限公司 | 一种治疗灰指甲的药物组合物 |
| US11554108B2 (en) * | 2016-08-29 | 2023-01-17 | Xeropedix, Inc. | Methods and compositions for treating cutaneous fungal infections |
| KR101952715B1 (ko) * | 2017-09-27 | 2019-02-27 | 경희대학교 산학협력단 | 천연 화합물을 포함하는 칸디다증 개선용 항진균 조성물 |
| BR112020013448A2 (pt) * | 2018-01-02 | 2020-12-01 | Scynexis, Inc. | composição injetável, métodos para tratar uma infecção fúngica e para preparar uma composição injetável. |
| RU2698454C1 (ru) * | 2018-11-12 | 2019-08-27 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО КубГМУ Минздрава России) | Способ лечения онихомикозов стоп |
| KR102072946B1 (ko) | 2019-08-06 | 2020-02-03 | 주식회사 씨엔엘바이오텍 | 조갑진균증 예방 또는 치료용 조성물 |
| EP4041839A4 (en) * | 2019-10-08 | 2023-10-11 | Hallux, Inc. | ONYCHOMYCOSIS TREATMENT COMPOSITIONS AND METHODS |
| AT524378A1 (de) | 2020-11-06 | 2022-05-15 | Univ Innsbruck | Zubereitung |
| WO2022123228A1 (en) * | 2020-12-08 | 2022-06-16 | Moberg Pharma Ab | Treatment regimen for onchyomycosis using allylamine antifungal compositions |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CY1410A (en) * | 1979-08-22 | 1988-04-22 | Sandoz Ag | Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals |
| US6005001A (en) * | 1991-05-20 | 1999-12-21 | Novartis Ag (Formerly Sandoz Ag) | Pharmaceutical composition |
| GB9111611D0 (en) * | 1991-05-30 | 1991-07-24 | Sandoz Ltd | Liposomes |
| DE69917609T2 (de) * | 1998-03-05 | 2005-06-09 | Phares Pharmaceutical Research N.V., Curaçao | Arzneimittel und deren verwendung |
| US6383471B1 (en) * | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
| GB0108082D0 (en) * | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
| US6846837B2 (en) * | 2002-06-21 | 2005-01-25 | Howard I. Maibach | Topical administration of basic antifungal compositions to treat fungal infections of the nails |
| US7473432B2 (en) | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
| WO2005087195A2 (en) * | 2004-03-18 | 2005-09-22 | Panacea Biotec Ltd. | Novel compositions for topical delivery |
| US20060078580A1 (en) * | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
| WO2006103638A2 (en) * | 2005-03-31 | 2006-10-05 | Ranbaxy Laboratories Limited | Topical pharmaceutical compositions of terbinafine and processes for their preparation |
| US20070077283A1 (en) * | 2005-09-30 | 2007-04-05 | Nastech Pharmaceutical Company Inc. | Method of enhancing transmucosal delivery of therapeutic compounds |
| JP5467722B2 (ja) * | 2007-01-16 | 2014-04-09 | ロート製薬株式会社 | 皮膚外用乳化製剤 |
| CN101652124A (zh) * | 2007-02-05 | 2010-02-17 | 亲生物有限公司 | 烯丙胺药物化合物的增加的效力 |
-
2009
- 2009-07-23 CN CN2009801337541A patent/CN102159202A/zh active Pending
- 2009-07-23 KR KR1020117004207A patent/KR20110039357A/ko not_active Withdrawn
- 2009-07-23 JP JP2011519254A patent/JP2011529038A/ja active Pending
- 2009-07-23 PE PE2011000073A patent/PE20110642A1/es not_active Application Discontinuation
- 2009-07-23 AU AU2009275230A patent/AU2009275230A1/en not_active Abandoned
- 2009-07-23 US US12/508,537 patent/US20100086504A1/en not_active Abandoned
- 2009-07-23 MX MX2011000932A patent/MX2011000932A/es not_active Application Discontinuation
- 2009-07-23 CA CA2731455A patent/CA2731455A1/en not_active Abandoned
- 2009-07-23 WO PCT/IB2009/006742 patent/WO2010010470A2/en not_active Ceased
- 2009-07-23 EP EP09786211A patent/EP2317993A2/en not_active Withdrawn
-
2010
- 2010-01-19 US US12/689,470 patent/US7820720B2/en not_active Expired - Fee Related
-
2011
- 2011-01-21 CL CL2011000135A patent/CL2011000135A1/es unknown
- 2011-01-21 NI NI201100025A patent/NI201100025A/es unknown
- 2011-01-23 IL IL210813A patent/IL210813A0/en unknown
- 2011-02-10 EC EC2011010818A patent/ECSP11010818A/es unknown
- 2011-02-15 CO CO11017742A patent/CO6351719A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010010470A3 (en) | 2010-03-18 |
| US7820720B2 (en) | 2010-10-26 |
| JP2011529038A (ja) | 2011-12-01 |
| NI201100025A (es) | 2011-11-02 |
| AU2009275230A1 (en) | 2010-01-28 |
| PE20110642A1 (es) | 2011-08-31 |
| CN102159202A (zh) | 2011-08-17 |
| US20100104633A1 (en) | 2010-04-29 |
| KR20110039357A (ko) | 2011-04-15 |
| ECSP11010818A (es) | 2011-05-31 |
| MX2011000932A (es) | 2011-05-19 |
| CA2731455A1 (en) | 2010-01-28 |
| WO2010010470A2 (en) | 2010-01-28 |
| EP2317993A2 (en) | 2011-05-11 |
| US20100086504A1 (en) | 2010-04-08 |
| CL2011000135A1 (es) | 2011-09-23 |
| IL210813A0 (en) | 2011-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |