CO6341477A2 - Compuestos pirrolopirimidincarboxamida, procesos para su producción y composiciones farmaceúticas que comprenden dichos compuestos - Google Patents

Compuestos pirrolopirimidincarboxamida, procesos para su producción y composiciones farmaceúticas que comprenden dichos compuestos

Info

Publication number
CO6341477A2
CO6341477A2 CO10071529A CO10071529A CO6341477A2 CO 6341477 A2 CO6341477 A2 CO 6341477A2 CO 10071529 A CO10071529 A CO 10071529A CO 10071529 A CO10071529 A CO 10071529A CO 6341477 A2 CO6341477 A2 CO 6341477A2
Authority
CO
Colombia
Prior art keywords
compounds
pirrolopirimidincarboxamida
processes
production
pharmaceutical compositions
Prior art date
Application number
CO10071529A
Other languages
English (en)
Inventor
Josef Stadlwieser
Beat Schmidt
Jorg Diefenbach
Degenhard Marx
Torsten Dunkern
Alexander Sudau
Heiko Bernsmann
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of CO6341477A2 publication Critical patent/CO6341477A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Los compuestos de la fórmula (I)en donde R1, R21, R22, R23, R24, Y y R3 tienen los significados dados en la descripción, las sales de los mismos, los N-óxidos de los compuestos, y las sales de los mismos y los estereoisómeros de los compuestos, las sales, los N-óxidos de los compuestos y los N-óxidos de las sales de los mismos, son efectivos inhibidores de la fosfodiesterasa tipo 5.
CO10071529A 2008-02-27 2010-06-15 Compuestos pirrolopirimidincarboxamida, procesos para su producción y composiciones farmaceúticas que comprenden dichos compuestos CO6341477A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08102052 2008-02-27

Publications (1)

Publication Number Publication Date
CO6341477A2 true CO6341477A2 (es) 2011-11-21

Family

ID=39855184

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10071529A CO6341477A2 (es) 2008-02-27 2010-06-15 Compuestos pirrolopirimidincarboxamida, procesos para su producción y composiciones farmaceúticas que comprenden dichos compuestos

Country Status (21)

Country Link
US (1) US8445501B2 (es)
EP (1) EP2247594A1 (es)
JP (1) JP5615187B2 (es)
KR (1) KR20100136469A (es)
CN (1) CN101959890B (es)
AR (1) AR070454A1 (es)
AU (1) AU2009218507B2 (es)
BR (1) BRPI0907863A2 (es)
CA (1) CA2711733A1 (es)
CO (1) CO6341477A2 (es)
EA (1) EA018331B1 (es)
EC (1) ECSP10010425A (es)
HK (1) HK1153200A1 (es)
IL (1) IL207639A (es)
MX (1) MX2010009276A (es)
MY (1) MY152061A (es)
NZ (1) NZ586486A (es)
SG (1) SG188823A1 (es)
TW (1) TW200944527A (es)
UA (1) UA101018C2 (es)
WO (1) WO2009106531A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2297114T (pt) 2008-06-19 2018-07-26 Takeda Pharmaceuticals Co Composto heterocíclico e a sua utilização
WO2010101247A1 (ja) 2009-03-05 2010-09-10 塩野義製薬株式会社 Ｎｐｙ ｙ５受容体拮抗作用を有するシクロヘキサン誘導体
US8816085B2 (en) * 2009-08-26 2014-08-26 Takeda Gmbh Methylpyrrolopyridinecarboxamides
AR077898A1 (es) 2009-08-26 2011-09-28 Nycomed Gmbh Metilpirrolopirimidincarboxamidas
CN103201244B (zh) * 2010-08-26 2015-06-17 阿尔比马尔公司 用于制备1-溴代-2-(环丙基甲氧基)-5-氟代-4-甲氧基苯的方法
BR112013031791A2 (pt) 2011-06-17 2017-01-31 Takeda Gmbh derivados de ftalazinona-pirrolopirimidinacarboxamida
US10527935B2 (en) 2016-12-31 2020-01-07 Rohm And Haas Electronic Materials Llc Radiation-sensitive compositions and patterning and metallization processes
JP2020097527A (ja) * 2017-03-31 2020-06-25 武田薬品工業株式会社 複素環化合物
KR102323090B1 (ko) * 2017-07-07 2021-11-05 상하이 인스티튜트 오브 마테리아 메디카 차이니즈 아카데미 오브 싸이언시즈 페닐 피리미돈 화합물의 염, 다형체 및 이의 약학 조성물 및 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754260B1 (fr) * 1996-10-04 1998-10-30 Adir Nouveaux derives substitues de biphenyle ou de phenylpyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6187777B1 (en) * 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US20050124623A1 (en) 2003-11-26 2005-06-09 Bender John A. Diazaindole-dicarbonyl-piperazinyl antiviral agents
AU2006221957A1 (en) * 2005-03-09 2006-09-14 Nycomed Gmbh Amido-substituted 6-phenylphenanthridines

Also Published As

Publication number Publication date
HK1153200A1 (en) 2012-03-23
EP2247594A1 (en) 2010-11-10
CA2711733A1 (en) 2009-09-03
JP2011513272A (ja) 2011-04-28
US20110021479A1 (en) 2011-01-27
UA101018C2 (ru) 2013-02-25
CN101959890B (zh) 2013-10-30
IL207639A0 (en) 2010-12-30
IL207639A (en) 2013-09-30
EA018331B1 (ru) 2013-07-30
WO2009106531A1 (en) 2009-09-03
AU2009218507A1 (en) 2009-09-03
EA201001348A1 (ru) 2011-04-29
SG188823A1 (en) 2013-04-30
TW200944527A (en) 2009-11-01
BRPI0907863A2 (pt) 2019-09-24
KR20100136469A (ko) 2010-12-28
CN101959890A (zh) 2011-01-26
NZ586486A (en) 2012-06-29
MX2010009276A (es) 2010-09-14
AU2009218507B2 (en) 2014-02-13
JP5615187B2 (ja) 2014-10-29
MY152061A (en) 2014-08-15
ECSP10010425A (es) 2010-09-30
US8445501B2 (en) 2013-05-21
AR070454A1 (es) 2010-04-07

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