CO6280531A2 - Novedosos derivados de 1,3 - Google Patents

Novedosos derivados de 1,3

Info

Publication number
CO6280531A2
CO6280531A2 CO10066630A CO10066630A CO6280531A2 CO 6280531 A2 CO6280531 A2 CO 6280531A2 CO 10066630 A CO10066630 A CO 10066630A CO 10066630 A CO10066630 A CO 10066630A CO 6280531 A2 CO6280531 A2 CO 6280531A2
Authority
CO
Colombia
Prior art keywords
thienyl
novedosos
derived
benzthiazolyl
indanyl
Prior art date
Application number
CO10066630A
Other languages
English (en)
Inventor
Yeong Geon Lee
Soo-Jung Choi
tae Kang
Mi-Jeong Seo
Chang-Yong Shin
Original Assignee
Dong A Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong A Pharm Co Ltd filed Critical Dong A Pharm Co Ltd
Publication of CO6280531A2 publication Critical patent/CO6280531A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

1.- Un derivado representado por la Fórmula 1 o una sal farmacéuticamente aceptable del mismo:en donde R1 es un fenilo sustituido o insustituido; o un heterociclilo seleccionado de piridinilo, isoxazolilo, tiazolilo, pirimidinilo, indanilo, benztiazolilo, pirazolilo, tiadiazolilo, oxazolilo, piperidinilo, morfolinilo, imidazolilo, pirrolidinilo, tienilo, triazolilo, pirrolilo y furilo; R2 es dialquilamino C1-C6, o un heterociclilo sustituido o insustituido seleccionado de piridinilo, isoxazolilo, tiazolilo, pirimidinilo, indanilo, benztiazolilo, pirazolilo, tiadiazolilo, oxazolilo, piperidinilo, morfolinilo, imidazolilo, pirrolidinilo, tienilo, triazolilo, pirrolilo y furilo; y n es un número entero de 1 a 3.
CO10066630A 2007-11-02 2010-06-02 Novedosos derivados de 1,3 CO6280531A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20070111783 2007-11-02
KR1020080105439A KR101103118B1 (ko) 2007-11-02 2008-10-27 신규한 1,3-디히드로-5-이소벤조퓨란카르보니트릴 유도체 화합물 및 이를 함유하는 조루증 치료용 약학조성물

Publications (1)

Publication Number Publication Date
CO6280531A2 true CO6280531A2 (es) 2011-05-20

Family

ID=40855892

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10066630A CO6280531A2 (es) 2007-11-02 2010-06-02 Novedosos derivados de 1,3

Country Status (20)

Country Link
US (1) US8242159B2 (es)
EP (1) EP2215070A4 (es)
JP (1) JP5281649B2 (es)
KR (1) KR101103118B1 (es)
CN (1) CN101910146A (es)
AR (1) AR069166A1 (es)
AU (1) AU2008319628B2 (es)
BR (1) BRPI0818267A2 (es)
CA (1) CA2703783C (es)
CL (1) CL2008003231A1 (es)
CO (1) CO6280531A2 (es)
IL (1) IL205350A0 (es)
MX (1) MX2010004727A (es)
NZ (1) NZ585091A (es)
PE (1) PE20091018A1 (es)
RU (1) RU2448963C2 (es)
TW (1) TWI365741B (es)
UA (1) UA99492C2 (es)
WO (1) WO2009057974A2 (es)
ZA (1) ZA201003794B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013026455A1 (en) * 2011-08-24 2013-02-28 Aarhus Universitet Permanently positively charged antidepressants
US9169237B1 (en) * 2014-10-24 2015-10-27 Medi Synergics, LLC Antiprotozoal amidine compounds
KR101637177B1 (ko) * 2014-03-14 2016-07-07 건일제약 주식회사 8-히드록시클로미프라민 또는 이의 약학적으로 허용가능한 염의 제조방법
ES2911910T3 (es) 2015-02-11 2022-05-23 Sunovion Pharmaceuticals Inc Compuestos de 1-heterociclilisocromanilo y análogos para tratar trastornos del SNC
CA3032141A1 (en) 2016-07-29 2018-02-01 Vadim ALEXANDROV Compounds and compositions and uses thereof
CN116514761A (zh) 2016-07-29 2023-08-01 赛诺维信制药公司 化合物、组合物及其用途
US10780074B2 (en) 2017-08-02 2020-09-22 Sunovion Pharmaceuticals Inc. Compounds and uses thereof
CN109111415B (zh) * 2018-10-25 2022-08-23 安徽中医药大学 一类石斛生物碱衍生物、制备方法和医药用途
EP3938045A1 (en) 2019-03-14 2022-01-19 Sunovion Pharmaceuticals Inc. Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB0105627D0 (en) * 2001-03-07 2001-04-25 Cipla Ltd Preparation of phthalanes
ATE326957T1 (de) * 2001-03-16 2006-06-15 Dmi Biosciences Inc Verwendung von tramadol zur verzögerung der ejakulation
JP2005510518A (ja) * 2001-11-08 2005-04-21 セプラコール， インク． シタロプラムのデスメチル代謝産物及びジデスメチル代謝産物の濃縮された鏡像異性体を用いてうつ病及び他のｃｎｓ障害を治療する方法
IN192863B (es) 2001-11-13 2004-05-22 Ranbaxy Lab Ltd
US6764200B1 (en) * 2003-01-15 2004-07-20 Hsiang Lan Wu Liu Decorative lantern
JP4667369B2 (ja) * 2003-03-21 2011-04-13 ネックスメド ホールディングス インコーポレイテッド 早漏を治療するための組成物および方法
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds

Also Published As

Publication number Publication date
EP2215070A2 (en) 2010-08-11
EP2215070A4 (en) 2011-11-02
KR101103118B1 (ko) 2012-01-04
JP5281649B2 (ja) 2013-09-04
TW200934481A (en) 2009-08-16
NZ585091A (en) 2012-04-27
ZA201003794B (en) 2011-02-23
KR20090045855A (ko) 2009-05-08
BRPI0818267A2 (pt) 2015-04-14
RU2448963C2 (ru) 2012-04-27
US8242159B2 (en) 2012-08-14
WO2009057974A2 (en) 2009-05-07
TWI365741B (en) 2012-06-11
AU2008319628B2 (en) 2012-03-29
RU2010122320A (ru) 2011-12-10
US20100240725A1 (en) 2010-09-23
UA99492C2 (ru) 2012-08-27
MX2010004727A (es) 2010-05-20
CA2703783C (en) 2012-12-04
CN101910146A (zh) 2010-12-08
JP2011502981A (ja) 2011-01-27
IL205350A0 (en) 2010-12-30
AU2008319628A1 (en) 2009-05-07
PE20091018A1 (es) 2009-08-17
CA2703783A1 (en) 2009-05-07
AR069166A1 (es) 2010-01-06
CL2008003231A1 (es) 2009-11-27
WO2009057974A3 (en) 2009-07-16

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