CO6260045A2 - Sistema de suministro de farmaco que comprende por lo menos un compartimento con una capa de nucleo de polimero termoplastica cargada con farmaco, una capa intermedia de polimero termoplastica cargada con farmaco y una piel de polimero termoplastica - Google Patents

Sistema de suministro de farmaco que comprende por lo menos un compartimento con una capa de nucleo de polimero termoplastica cargada con farmaco, una capa intermedia de polimero termoplastica cargada con farmaco y una piel de polimero termoplastica

Info

Publication number
CO6260045A2
CO6260045A2 CO10033049A CO10033049A CO6260045A2 CO 6260045 A2 CO6260045 A2 CO 6260045A2 CO 10033049 A CO10033049 A CO 10033049A CO 10033049 A CO10033049 A CO 10033049A CO 6260045 A2 CO6260045 A2 CO 6260045A2
Authority
CO
Colombia
Prior art keywords
thermoplastic polymer
loaded
pharmaco
delivery system
coat
Prior art date
Application number
CO10033049A
Other languages
English (en)
Inventor
Graaff Wouter De
Raymond Zeeman
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40329142&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6260045(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organon Nv filed Critical Organon Nv
Publication of CO6260045A2 publication Critical patent/CO6260045A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
    • A61F6/142—Wirelike structures, e.g. loops, rings, spirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1.- Un sistema de suministro de fármaco que comprende por o menos un compartimiento que comprende (i) una capa de núcleo de polímero termoplástica cargada con fármaco, (ii) una capa intermedia de polímero termoplástica cargada con fármaco y (iii) una piel de polímero termoplástica no medicada que cubre la capa intermedia, en donde dicha capa de núcleo se carga con cristales de un primer compuesto activo farmacéuticamente y en donde dicha capa intermedia se carga con cristales del segundo compuesto, en particular un compuesto activo farmacéuticamente. 2.- Un sistema de suministro de fármaco de acuerdo con la reivindicación 1, caracterizado porque la capa de núcleo forma el núcleo del sistema de suministro de fármaco. 3.- Un sistema de suministro de fármaco de acuerdo con la reivindicación 1, caracterizado por un núcleo no medicado adicional que está cubierto por la capa de núcleo. 4.- Un sistema de suministro de fármaco de acuerdo con la reivindicación 1, caracterizado por una capa intermedia no medicada adicional entre la capa de núcleo y la capa intermedia cargada con fármaco. 5.- Un sistema de suministro de fármaco de acuerdo con una cualquiera de las reivindicaciones 1-4, caracterizado porque el sistema de suministro tiene la forma de un anillo, un implante, un sistema intrauterino (IUS), una bobina helicoidal, o un resorte.
CO10033049A 2007-09-21 2010-03-19 Sistema de suministro de farmaco que comprende por lo menos un compartimento con una capa de nucleo de polimero termoplastica cargada con farmaco, una capa intermedia de polimero termoplastica cargada con farmaco y una piel de polimero termoplastica CO6260045A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07018584 2007-09-21

Publications (1)

Publication Number Publication Date
CO6260045A2 true CO6260045A2 (es) 2011-03-22

Family

ID=40329142

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10033049A CO6260045A2 (es) 2007-09-21 2010-03-19 Sistema de suministro de farmaco que comprende por lo menos un compartimento con una capa de nucleo de polimero termoplastica cargada con farmaco, una capa intermedia de polimero termoplastica cargada con farmaco y una piel de polimero termoplastica

Country Status (19)

Country Link
US (2) US8741329B2 (es)
EP (1) EP2200547A1 (es)
JP (1) JP5380452B2 (es)
KR (2) KR20100085054A (es)
CN (1) CN101827569B (es)
AR (1) AR066166A1 (es)
AU (1) AU2008300825B2 (es)
BR (1) BRPI0816887A8 (es)
CA (1) CA2699266C (es)
CL (1) CL2008002810A1 (es)
CO (1) CO6260045A2 (es)
EC (1) ECSP10010079A (es)
MX (1) MX2010003107A (es)
MY (1) MY163892A (es)
NZ (1) NZ583874A (es)
RU (1) RU2488369C2 (es)
TW (1) TW200930343A (es)
WO (1) WO2009036999A1 (es)
ZA (1) ZA201002014B (es)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
JP5137841B2 (ja) 2005-10-13 2013-02-06 シンセス ゲーエムベーハー 薬物含浸容器
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
CN101500583B (zh) * 2006-07-12 2012-05-23 控制治疗（苏格兰）有限公司 含克林霉素盐酸盐的药物递送聚合物
GB0620685D0 (en) * 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
WO2010105995A2 (en) * 2009-03-17 2010-09-23 Intervet International B.V. Zoo-technical drug delivery device
US8568374B2 (en) * 2009-05-04 2013-10-29 Merck Sharp & Dohme B.V. Intrauterine system
FI20095563A (fi) * 2009-05-20 2010-11-21 Bayer Schering Pharma Oy Vaginaalinen antojärjestelmä
ES2921527T3 (es) 2009-06-03 2022-08-29 Forsight Vision5 Inc Administración de fármaco en segmento anterior
KR101914119B1 (ko) * 2010-03-16 2018-11-02 타이탄 파머슈티컬즈 인코퍼레이티드 약물 전달용 이종 이식가능 장치
DE102010003494A1 (de) * 2010-03-31 2011-10-06 Bayer Schering Pharma Aktiengesellschaft Parenterales Abgabesystem, das Aromatasehemmer und Gestagene freisetzt, für die Behandlung von Endometriose
US8939948B2 (en) 2010-06-01 2015-01-27 Forsight Vision5, Inc. Ocular insert apparatus and methods
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
US11351122B1 (en) 2010-07-28 2022-06-07 Laboratorios Leon Farma Sa Synthetic progestogens and pharmaceutical compositions comprising the same
US9603860B2 (en) 2010-07-28 2017-03-28 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
AU2012268068B2 (en) * 2011-06-06 2016-10-13 Auritec Pharmaceuticals Drug delivery device employing wicking release window
LT2782584T (lt) 2011-11-23 2021-09-10 Therapeuticsmd, Inc. Natūralios kombinuotos pakaitinės hormonų terapijos kompozicijos ir gydymas
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
AR089765A1 (es) * 2012-01-23 2014-09-17 Bayer Oy Un sistema para el suministro de un farmaco
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
CN104884006B (zh) 2012-10-26 2017-12-15 弗赛特影像5股份有限公司 用于持续释放药物到眼睛的眼科系统
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20160144067A1 (en) 2013-06-21 2016-05-26 DePuy Synthes Products, Inc. Films and methods of manufacture
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
JP6936801B2 (ja) * 2015-12-21 2021-09-22 バイエル・オーイュー 薬剤送達装置の製造方法およびその方法に従って製造された薬剤送達装置
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
US11766400B2 (en) * 2016-10-24 2023-09-26 Yale University Biodegradable contraceptive implants
SG11202005947RA (en) 2018-05-24 2020-07-29 Celanese Eva Performance Polymers Corp Implantable device for sustained release of a macromolecular drug compound
WO2019222856A1 (en) 2018-05-24 2019-11-28 Nureva Inc. Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones
WO2019226519A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
EP3893884A4 (en) * 2018-12-11 2022-09-14 Lupin Inc. EXTREMELY LOW COMBINATION OF ESTROGEN COMBINATIONS DRUG DELIVERY SYSTEM, AND METHODS AND USES THEREOF
DE102019115343A1 (de) * 2019-06-06 2020-12-10 EVESTRA GmbH Vaginalring für die hormonelle Kontrazeption
EP4215181A1 (en) * 2022-01-21 2023-07-26 Sever Pharma Solutions An intravaginal ring
EP4215180A1 (en) * 2022-01-21 2023-07-26 Sever Pharma Solutions A drug delivery system

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3545439A (en) 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3995634A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal cavity dispensing means and method
US3995633A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal Medicament dispensing device
US4237885A (en) 1978-10-23 1980-12-09 Alza Corporation Delivery system with mated members for storing and releasing a plurality of beneficial agents
US4292965A (en) 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
DE3040978A1 (de) 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
US4629449A (en) 1982-07-29 1986-12-16 Alza Corporation Vaginal dispenser for dispensing beneficial hormone
US4596576A (en) 1984-10-12 1986-06-24 Akzo N.V. Release system for two or more active substances
ATE86484T1 (de) 1987-08-08 1993-03-15 Akzo Nv Kontrazeptives implantat.
AU3432689A (en) 1988-03-24 1989-10-16 Bukh Meditec A/S Controlled release composition
DK606288D0 (da) * 1988-03-24 1988-10-31 Bukh Meditec Praeparat
US5766632A (en) 1993-10-01 1998-06-16 Legere Pharmaceuticals, Ltd. Method of using lectins for contraception
JP3720386B2 (ja) 1993-12-27 2005-11-24 住友製薬株式会社 薬物放出制御製剤
ES2166894T3 (es) 1995-07-04 2002-05-01 Akzo Nobel Nv Dispositivos anulares.
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
FR2754179B1 (fr) 1996-10-08 1998-12-24 Theramex Nouvelle composition hormononale et son utilisation
IL123813A0 (en) 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
ES2205594T3 (es) 1997-12-12 2004-05-01 Akzo Nobel N.V. Envase para anillo vaginal.
TR200002179T2 (tr) * 1997-12-18 2001-07-23 Eli Lilly And Company Kristalin teriparatid.
TW586944B (en) 1998-05-29 2004-05-11 Sumitomo Pharma Controlled release agent having a multi-layer structure
US6579533B1 (en) 1999-11-30 2003-06-17 Bioasborbable Concepts, Ltd. Bioabsorbable drug delivery system for local treatment and prevention of infections
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
CN1536986B (zh) 2001-03-27 2012-07-04 沃纳奇尔科特(爱尔兰)有限公司 用于抗微生物剂给药的阴道内药物递送装置
CA2451187C (en) 2001-06-22 2012-08-14 Southern Biosystems, Inc. Zero-order prolonged release coaxial implants
WO2003017971A1 (en) * 2001-08-31 2003-03-06 Schering Oy Drug delivery system
CN1596101A (zh) 2001-09-28 2005-03-16 麦克内尔-Ppc股份有限公司 含有糖果组分的剂型
US6992219B2 (en) * 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
US20070043332A1 (en) 2003-07-10 2007-02-22 Galen (Chemiclas) Liimited Intravaginal drug delivery devices
WO2005089723A1 (en) * 2004-03-24 2005-09-29 N.V. Organon Drug delivery system based on polyethylene vinylacetate copolymers
TW200727920A (en) 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
PE20081895A1 (es) 2007-03-26 2009-01-26 Theramex Regimen anticonceptivo oral
DK2207529T3 (en) 2007-09-07 2015-03-09 Mati Therapeutics Inc PHARMACEUTICAL cores for the sustained release of therapeutic agents

Also Published As

Publication number Publication date
CN101827569A (zh) 2010-09-08
JP2010539205A (ja) 2010-12-16
CA2699266A1 (en) 2009-03-26
AR066166A1 (es) 2009-07-29
RU2010115785A (ru) 2011-10-27
MY163892A (en) 2017-11-15
KR20150046323A (ko) 2015-04-29
RU2488369C2 (ru) 2013-07-27
EP2200547A1 (en) 2010-06-30
BRPI0816887A8 (pt) 2016-01-12
AU2008300825B2 (en) 2013-06-06
CL2008002810A1 (es) 2009-06-05
ZA201002014B (en) 2010-11-24
BRPI0816887A2 (pt) 2015-03-24
US20090081278A1 (en) 2009-03-26
US8741329B2 (en) 2014-06-03
NZ583874A (en) 2012-04-27
US20140056962A1 (en) 2014-02-27
ECSP10010079A (es) 2010-04-30
WO2009036999A1 (en) 2009-03-26
MX2010003107A (es) 2010-04-21
CN101827569B (zh) 2013-10-16
AU2008300825A1 (en) 2009-03-26
TW200930343A (en) 2009-07-16
CA2699266C (en) 2016-08-30
JP5380452B2 (ja) 2014-01-08
KR20100085054A (ko) 2010-07-28

Similar Documents

Publication Publication Date Title
CO6260045A2 (es) Sistema de suministro de farmaco que comprende por lo menos un compartimento con una capa de nucleo de polimero termoplastica cargada con farmaco, una capa intermedia de polimero termoplastica cargada con farmaco y una piel de polimero termoplastica
ECSP056250A (es) Sistema de liberación de fármacos
AR063958A1 (es) Metodos para administrar medicaciones para la perdida de peso
CL2008003595A1 (es) Compuestos heterociclicos nitrogenados, antagonistas del receptor de taquiquinina; agente farmaceutico que comprende el compuesto; y uso en la profilaxis o el tratamiento de una enfermedad del tracto urinario inferior, una enfermedad gastrointestinal o una enfermedad del sistema nervioso central.
ES2531215T3 (es) Sistemas de administración de fármacos que comprenden un agente de bloqueo selectivo de la serotonina 5-HT3 débilmente básico y ácidos orgánicos
CO6650415A2 (es) Nuevas formas de dosificacion de liberación modificada de un inhibidor de la xantina oxidorreductasa o de inhibidoes de xantina oxidasa
AR062644A1 (es) Tecnologia de suministro programable flotante
ATE419842T1 (de) Abgabevehikel mit nanoteilchen
SV2015005115A (es) Derivados de la pirazolopirrolidina y su uso en el tratamiento de enfermedades
CO6470799A2 (es) Composición farmacéutica oral auto-microemulsificante de un farmaco hidrofílico y método de preparación de ésta
UY27532A1 (es) Forma de dosificación de liberación controlada dual.
ECSP10010104A (es) Sistema de administración vaginal
AR076123A1 (es) Dispositivo de suministro de droga zootecnica. metodo.
NZ603579A (en) Controlled release formulations
AR060019A1 (es) Composicion farmaceutica, producto y metodo de tratamiento para un trastorno cognitivo y usos de un inhibidor de acetilcolinesterasa y un antagonista de 5- ht6 en la fabricacion de un medicamento para el tratamiento de un trastorno cognitivo
PE20080338A1 (es) 4-[5-(2-amino-etansulfonil)-isoquinolin-7-il]-fenol como inhibidor de akt (proteina cinasa)
CL2009001077A1 (es) Vehiculo particulado polimerico que comprende un agente biologico en fase acuosa en un lumen hueco; procedimiento para suministrar una proteina en el ojo; composicion farmaceutica que comprende dicho vehiculo; y su uso para profilaxis y tratar enfermedades o trastornos del ojo.
CO6400184A2 (es) Formulaciones galénicas de compuestos orgánicos
UY37293A (es) Forma farmacéutica de unidades múltiples que comprende un núcleo con unidades centrales individuales cubiertas por un material muco-adhesivo, y un recubrimiento de núcleo entérico
WO2017046215A3 (en) Pharmaceutical association comprising a growth factor receptor agonist conjugated to a bioactive carrier for converting a neoplastic cell into a non-neoplastic cell and uses thereof
EA202090637A1 (ru) Способы применения дипивефрина
GT201400042A (es) Compuesto de benzotiazolona
AR065528A1 (es) Forma de dosificacion que comprende 6-(3- coclobutil -2,3,4,5- tetrahidro -1h - benzo (d) azepin -7-iloxi)-n - metil- nicotinamida , metodo para producirla, su uso para preparar un medicamento y solucion o suspension que los comprende
AR071727A1 (es) Parche para reemplazar una porcion de pared de la vejiga
NI201000213A (es) Uso del antagonista de la histamina h4 para el tratamiento de adherencias postoperatorias

Legal Events

Date Code Title Description
FC Application refused