CO5570687A2 - Composiciones de valdecoxib de disgregacion intraoral preparadas mediante un procedimiento de desecacion por pulverizacion - Google Patents

Composiciones de valdecoxib de disgregacion intraoral preparadas mediante un procedimiento de desecacion por pulverizacion

Info

Publication number
CO5570687A2
CO5570687A2 CO04033066A CO04033066A CO5570687A2 CO 5570687 A2 CO5570687 A2 CO 5570687A2 CO 04033066 A CO04033066 A CO 04033066A CO 04033066 A CO04033066 A CO 04033066A CO 5570687 A2 CO5570687 A2 CO 5570687A2
Authority
CO
Colombia
Prior art keywords
valdecoxib
composition
pharmaceutically acceptable
oral dissolution
desection
Prior art date
Application number
CO04033066A
Other languages
English (en)
Inventor
Joseph P Reo
J Shah Uday
Yamamoto Ken
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of CO5570687A2 publication Critical patent/CO5570687A2/es

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P7/06Antianaemics
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)

Abstract

1.- Una composición oral de disolución rápida que comprende:(a) un particulado de valdecoxib en una cantidad terapéuticamente efectiva, y (b) al menos un excipiente farmacéuticamente aceptable que muestra una rápida disolución oral y que está en asociación íntima con las partículas de valdecoxib;en la que el al menos un excipiente que muestra una rápida disolución oral está presente en una cantidad total de aproximadamente el 50% a aproximadamente el 99% en peso.2.- La composición de la Reivindicación 1, en la que el al menos un excipiente farmacéuticamente aceptable que muestra una rápida disolución oral es un carbohidrato.3.- La composición de la Reivindicación 1, en la que el al menos un excipiente farmacéuticamente aceptable que muestra una rápida disolución oral es un sacárido.4.- La composición de la Reivindicación 1, en la que el al menos un excipiente farmacéuticamente aceptable que muestra una rápida disolución oral se elige del grupo consistente en maltosa, maltitol, sorbitol, lactosa y manitol.5.- La composición de la Reivindicación 1, en la que el al menos un excipiente que muestra una rápida disolución oral esta presente en una cantidad total de aproximadamente el 50% a aproximadamente el 90% en peso.
CO04033066A 2001-10-10 2004-04-07 Composiciones de valdecoxib de disgregacion intraoral preparadas mediante un procedimiento de desecacion por pulverizacion CO5570687A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32808801P 2001-10-10 2001-10-10

Publications (1)

Publication Number Publication Date
CO5570687A2 true CO5570687A2 (es) 2005-10-31

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CO04033066A CO5570687A2 (es) 2001-10-10 2004-04-07 Composiciones de valdecoxib de disgregacion intraoral preparadas mediante un procedimiento de desecacion por pulverizacion

Country Status (28)

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EP (1) EP1450769A1 (es)
JP (1) JP2005508348A (es)
KR (1) KR20050035138A (es)
CN (1) CN1602187A (es)
AP (1) AP2004003022A0 (es)
BG (1) BG108675A (es)
BR (1) BR0213152A (es)
CA (1) CA2462881A1 (es)
CO (1) CO5570687A2 (es)
CZ (1) CZ2004456A3 (es)
EA (1) EA200400423A1 (es)
EC (1) ECSP045056A (es)
GE (1) GEP20063857B (es)
HR (1) HRP20040331A2 (es)
HU (1) HUP0401776A2 (es)
IL (1) IL161253A0 (es)
IS (1) IS7211A (es)
MA (1) MA27543A1 (es)
MX (1) MXPA04003404A (es)
NO (1) NO20041894L (es)
NZ (1) NZ532184A (es)
OA (1) OA12666A (es)
PL (1) PL370136A1 (es)
SK (1) SK1662004A3 (es)
TN (1) TNSN04056A1 (es)
WO (1) WO2003030876A1 (es)
YU (1) YU37104A (es)
ZA (1) ZA200402728B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7815937B2 (en) 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
WO2012087113A1 (en) * 2010-12-24 2012-06-28 N.V. Nutricia Improved nutritional tablet

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
KR100373622B1 (ko) * 1996-05-17 2003-07-12 머크 앤드 캄파니 인코포레이티드 사이클로옥시게나제-2로매개된질환의1일1회치료용조성물
KR100664479B1 (ko) * 1999-12-08 2007-01-04 파마시아 코포레이션 발데콕시브 조성물
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
US20020071857A1 (en) * 2000-08-18 2002-06-13 Kararli Tugrul T. Rapidly disintegrating oral formulation of a cyclooxygenase-2 inhibitor
CN1638739A (zh) * 2000-08-18 2005-07-13 法玛西雅厄普约翰美国公司 治疗成瘾性障碍的化合物

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Publication number Publication date
IL161253A0 (en) 2004-09-27
CZ2004456A3 (cs) 2005-03-16
HRP20040331A2 (en) 2005-12-31
CA2462881A1 (en) 2003-04-17
NO20041894D0 (no) 2004-05-07
GEP20063857B (en) 2006-06-26
YU37104A (sh) 2006-08-17
NZ532184A (en) 2005-12-23
WO2003030876A1 (en) 2003-04-17
CN1602187A (zh) 2005-03-30
BR0213152A (pt) 2004-10-19
PL370136A1 (en) 2005-05-16
AP2004003022A0 (en) 2004-06-30
HUP0401776A2 (hu) 2004-12-28
BG108675A (en) 2005-03-31
EP1450769A1 (en) 2004-09-01
ECSP045056A (es) 2004-08-27
JP2005508348A (ja) 2005-03-31
TNSN04056A1 (fr) 2006-06-01
MXPA04003404A (es) 2004-06-18
MA27543A1 (fr) 2005-10-03
IS7211A (is) 2004-04-07
OA12666A (en) 2006-06-19
KR20050035138A (ko) 2005-04-15
SK1662004A3 (sk) 2005-07-01
EA200400423A1 (ru) 2004-10-28
ZA200402728B (en) 2005-03-17
NO20041894L (no) 2004-07-07

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