CO5261600A1 - 4-alquenil (y alquinil) oxindoles - Google Patents

4-alquenil (y alquinil) oxindoles

Info

Publication number
CO5261600A1
CO5261600A1 CO99078069A CO99078069A CO5261600A1 CO 5261600 A1 CO5261600 A1 CO 5261600A1 CO 99078069 A CO99078069 A CO 99078069A CO 99078069 A CO99078069 A CO 99078069A CO 5261600 A1 CO5261600 A1 CO 5261600A1
Authority
CO
Colombia
Prior art keywords
alkyl
nr6r7
optionally substituted
conr8r9
conr6r7
Prior art date
Application number
CO99078069A
Other languages
English (en)
Inventor
Chen Yi
Wendy Lea Corbett
Dermatakis Apostolos
Liu Jin-Jun
Luk Kin-Chun
Paige Erin Mahaney
Steven Gregory Mischke
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CO5261600A1 publication Critical patent/CO5261600A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compuestos de fórmula (I) <EMI FILE="99078069_1" ID="1" IMF=JPEG >y profármacos y metabolitos farmacéuticamente activos de los compuestos de la fórmula I; y las sales farmacéuticamente aceptables de los anteriores compuestos; donde R1 es hidrógeno; -COR4 ; -COOR4; -CONR6R7; alquilo C1-C6 opcionalmente sustituido con uno o más de -OR5, -NR6R7; cicloalquilo, heterociclo, -COR4, COOR4, -CONR6R7, -CN, -NO2, -SO2R4, halógeno, y -SO2NR6R7; cicloalquilo opcionalmente sustituido con uno o más de -OR5, -NR6R7, alquilo C1-C6, heterociclo, -COR4, -COOR4, -CONR6R7; -CN, -NO2, -SO2R4, halógeno, y -SO2NR6R7; heterociclo opcionalmente sustituido con uno o más de -OR5, -NR6R7, alquilo C1-C6, cicloalquilo, -COR4, -COOR4, -CONR6R7, -CN, -NO2, -SO2R4, halógeno, y -SO2N R6R7 ;R2 es hidrógeno, -OR4, -COOR4, -CONR6R7, -NR6R7, halógeno, -NO2, -CN, -SO2R4, -SO2NR6R7, perfluoroalquilo, alquilo C1-C6 o alquilo C1-C6 sustituido por -OR8 y/o -NR6R7; R3 es hidrógeno, -OR4, -COR4, -COOR4, -CONR6R7, halógeno, -CN, -NR6R7, perfluoroalquilo, alquilo C1-C6 o alquilo C1-C6 sustituido por -OR8 y/o -NR6R7;R4 es hidrógeno; alquilo C1-C6 opcionalmente sustituido con uno o más de -OR5, -COOR8, -COR8, -CONR8R9, -NR6R7, cicloalquilo, heterociclo, -CN, -NO2, -SO2R8, y -SO2NR8R9; cicloalquilo opcionalmente sustituido con uno o más de -OR5, -COOR8, -COR8, -CONR8R9, -NR6R7, alquilo C1-C6, heterociclo, -CN, -NO2, -SO2R8, y -SO2NR8R9; o heterociclo opcionalmente sustituido con uno o más de -OR5, -COOR3, -COR8, -CONR8R9, -NR6R7, alquilo C1-C6 cicloalquilo, -CN, -NO2, -SO2R8, y -SO2NR8R9; R5 es hidrógeno, -COR8; -CONR8R9; alquilo C1-C6 alquilo C1-C6 sustituido con uno o más de -OR9, -NR9R10, -N(COR9)R10, -COR9, -CONR9R10, y -COOR9; R5 y R7 son cada uno independientemente hidrógeno, -COR8, -COOR8, -CONR8R9; SO2R3; -SO2NR8R9; alquilo C1-C6 opcionalmente sustituido con uno o más de -OR5, -NR8R9, -COOR8, -COR8, -CONR8R9, -CN, -NO2, -SO2R8, ...
CO99078069A 1998-12-17 1999-12-14 4-alquenil (y alquinil) oxindoles CO5261600A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11259198P 1998-12-17 1998-12-17
US14907399P 1999-08-16 1999-08-16

Publications (1)

Publication Number Publication Date
CO5261600A1 true CO5261600A1 (es) 2003-03-31

Family

ID=26810131

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99078069A CO5261600A1 (es) 1998-12-17 1999-12-14 4-alquenil (y alquinil) oxindoles

Country Status (20)

Country Link
US (3) US6130239A (es)
EP (1) EP1157019B1 (es)
JP (1) JP2002532492A (es)
KR (1) KR100649925B1 (es)
CN (1) CN1138773C (es)
AR (1) AR024847A1 (es)
AT (1) ATE234830T1 (es)
AU (1) AU770375B2 (es)
BR (1) BR9916327A (es)
CA (1) CA2354873A1 (es)
CO (1) CO5261600A1 (es)
DE (1) DE69906152T2 (es)
DK (1) DK1157019T3 (es)
ES (1) ES2192877T3 (es)
PE (1) PE20001537A1 (es)
PT (1) PT1157019E (es)
TR (1) TR200101860T2 (es)
TW (1) TW550262B (es)
UY (1) UY25857A1 (es)
WO (1) WO2000035908A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6569868B2 (en) 1998-04-16 2003-05-27 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
TR200101860T2 (tr) * 1998-12-17 2001-12-21 F.Hoffmann-La Roche Ag Sikline bağlı kinaz inhibitörleri olarak 4-alkenil (ve alkinil) oksidoller
PT1233943E (pt) * 1999-11-24 2011-09-01 Sugen Inc Formulações para agentes farmacêuticos ionizáveis como ácidos livres ou bases livres
US6878733B1 (en) 1999-11-24 2005-04-12 Sugen, Inc. Formulations for pharmaceutical agents ionizable as free acids or free bases
PT1255536E (pt) * 1999-12-22 2006-09-29 Sugen Inc Derivados de indolinona para a modulacao da tirosina proteina cinase de tipo c-kit
ME00415B (me) * 2000-02-15 2011-10-10 Pharmacia & Upjohn Co Llc Pirol supstituisani 2-indol protein kinazni inhibitori
EP1272483A2 (en) * 2000-03-24 2003-01-08 Millenium Pharmaceuticals, Inc. OXINDOLE INHIBITORS OF FACTOR Xa
TWI270545B (en) 2000-05-24 2007-01-11 Sugen Inc Mannich base prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
JP2003535847A (ja) 2000-06-02 2003-12-02 スージェン・インコーポレーテッド 蛋白質キナーゼ／ホスファターゼ阻害剤としてのインドリノン誘導体
CA2414468A1 (en) * 2000-06-30 2002-01-10 Sugen, Inc. 4-heteroaryl-3-heteroarylidenyl-2-indolinones and their use as protein kinase inhibitors
AR035721A1 (es) * 2000-12-20 2004-07-07 Sugen Inc Indolinonas 4-aril sustituidas; sus composiciones farmaceuticas y metodo para modular la actividad catalitica de una proteina quinasa
US6504034B2 (en) * 2001-01-23 2003-01-07 Hoffmann-La Roche Inc. Naphthostyrils
AR042586A1 (es) 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
FR2822155B1 (fr) 2001-03-13 2003-12-12 Aventis Pharma Sa Composes derives des oxindoles et leur application therapeutique en cancerologie
DK3168218T3 (en) * 2001-08-15 2019-01-14 Pharmacia & Upjohn Co Llc Crystalline comprising an L-malic acid salt of N- [2- (DIETHYLAMINO) ETHYL] -5 - [(5-FLUOR-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDE) METHYL] -2,4 -DIMETHYL-1H-PYRROL-3-CARBOXAMIDE FOR USE AS A MEDICINE
WO2003031438A1 (en) 2001-10-10 2003-04-17 Sugen, Inc. 3-[4-(substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2-indolinone derivatives as kinase inhibitors
DE60205776T2 (de) * 2001-12-27 2006-06-14 Theravance Inc Indolinon-derivative als protein-kinasehemmer
FR2948940B1 (fr) * 2009-08-04 2011-07-22 Servier Lab Nouveaux derives dihydroindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2012178015A2 (en) * 2011-06-24 2012-12-27 Zenobia Therapeutics, Inc. Lrrk2 inhibitors
CN106187904B (zh) * 2015-05-25 2021-07-06 中国医学科学院药物研究所 含丙炔酰胺基的2-苯基咪唑类衍生物及其制法和药物组合物与用途
KR102616949B1 (ko) 2017-09-14 2023-12-22 다이이찌 산쿄 가부시키가이샤 고리형 구조를 갖는 화합물
WO2022113003A1 (en) 2020-11-27 2022-06-02 Rhizen Pharmaceuticals Ag Cdk inhibitors
WO2022149057A1 (en) 2021-01-05 2022-07-14 Rhizen Pharmaceuticals Ag Cdk inhibitors
KR20240020735A (ko) 2021-05-07 2024-02-15 카이메라 쎄라퓨틱스 인코포레이티드 Cdk2 분해제 및 그 용도

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US5086186A (en) * 1989-05-25 1992-02-04 Pfizer Inc. N-trichloroacetyl-2-oxindole-1-carboxamides
DE69031649T2 (de) * 1989-07-25 1998-02-26 Taiho Pharmaceutical Co Ltd Oxoindolderivate
WO1991009598A1 (en) * 1990-01-05 1991-07-11 Pfizer Inc. Azaoxindole derivatives
GB9004483D0 (en) * 1990-02-28 1990-04-25 Erba Carlo Spa New aryl-and heteroarylethenylene derivatives and process for their preparation
WO1992007830A2 (en) * 1990-10-29 1992-05-14 Pfizer Inc. Oxindole peptide antagonists
GB9115160D0 (en) * 1991-07-12 1991-08-28 Erba Carlo Spa Methylen-oxindole derivatives and process for their preparation
US5322950A (en) * 1991-12-05 1994-06-21 Warner-Lambert Company Imidazole with angiotensin II antagonist properties
FR2694004B1 (fr) * 1992-07-21 1994-08-26 Adir Nouvelles 3-(Hydroxybenzylidényl)-indoline-2-ones et 3-(hydroxybenzylidényl)-indoline-2-thiones, leurs procédés de préparation, et les compositions pharmaceutiques qui les contiennent.
GB9226855D0 (en) * 1992-12-23 1993-02-17 Erba Carlo Spa Vinylene-azaindole derivatives and process for their preparation
GB9313638D0 (en) * 1993-07-01 1993-08-18 Erba Carlo Spa Arylidene and heteroarylidene oxindole derivatives and process for their preparation
GB9326136D0 (en) * 1993-12-22 1994-02-23 Erba Carlo Spa Biologically active 3-substituted oxindole derivatives useful as anti-angiogenic agents
GB9412719D0 (en) * 1994-06-24 1994-08-17 Erba Carlo Spa Substituted azaindolylidene compounds and process for their preparation
GB9423997D0 (en) * 1994-11-28 1995-01-11 Erba Carlo Spa Substituted 3-arylidene-7-azaoxindole compounds and process for their preparation
GB9501567D0 (en) * 1995-01-26 1995-03-15 Pharmacia Spa Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors
GB9507298D0 (en) * 1995-04-07 1995-05-31 Pharmacia Spa Substituted indolylmethylene-oxindale analogues as tyrosine kinase inhibitors
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
JPH11512708A (ja) * 1995-09-11 1999-11-02 オステオアルスリィティス サイエンシズ，インコーポレイテッド 変形性関節炎を治療するためのプロテインチロシンキナーゼインヒビター
US5733920A (en) * 1995-10-31 1998-03-31 Mitotix, Inc. Inhibitors of cyclin dependent kinases
GB9610964D0 (en) * 1996-05-24 1996-07-31 Pharmacia & Upjohn Spa Substituted tetralylmethylen-oxindole analogues as tyrosine kinase inhibitors
GB9611797D0 (en) * 1996-06-06 1996-08-07 Pharmacia Spa Substituted quinolylmethylen-oxindole analogues as tyrosine kinase inhibitors
EP0929520B1 (en) * 1996-08-23 2005-11-02 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
WO1998024432A2 (en) * 1996-12-05 1998-06-11 Sugen, Inc. Use of indolinone compounds as modulators of protein kinases
EP0984930B1 (en) * 1997-05-07 2005-04-06 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
GB9716557D0 (en) * 1997-08-06 1997-10-08 Glaxo Group Ltd Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity
GB9718913D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
JP2002507598A (ja) * 1998-03-26 2002-03-12 スージェン・インコーポレーテッド チロシン蛋白質キナーゼを調節するためのヘテロ環式化合物のファミリー
IL139934A0 (en) * 1998-05-29 2002-02-10 Sugen Inc Pyrrole substituted 2-indolinone derivatives and pharmaceutical compositions containing the same
AU5468499A (en) * 1998-08-04 2000-02-28 Sugen, Inc. 3-methylidenyl-2-indolinone modulators of protein kinase
JP2002523455A (ja) * 1998-08-31 2002-07-30 スージェン・インコーポレーテッド 蛋白質キナーゼ活性の調節剤としての幾何学的に制限された２−インドリノン誘導体
TR200101860T2 (tr) * 1998-12-17 2001-12-21 F.Hoffmann-La Roche Ag Sikline bağlı kinaz inhibitörleri olarak 4-alkenil (ve alkinil) oksidoller

Also Published As

Publication number Publication date
PE20001537A1 (es) 2001-01-09
US6303793B1 (en) 2001-10-16
ES2192877T3 (es) 2003-10-16
CN1138773C (zh) 2004-02-18
AR024847A1 (es) 2002-10-30
EP1157019A1 (en) 2001-11-28
JP2002532492A (ja) 2002-10-02
KR100649925B1 (ko) 2007-02-28
BR9916327A (pt) 2001-09-18
DE69906152D1 (de) 2003-04-24
CN1330647A (zh) 2002-01-09
TR200101860T2 (tr) 2001-12-21
AU1972700A (en) 2000-07-03
PT1157019E (pt) 2003-06-30
CA2354873A1 (en) 2000-06-22
DK1157019T3 (da) 2003-07-14
KR20010101274A (ko) 2001-11-14
TW550262B (en) 2003-09-01
UY25857A1 (es) 2001-07-31
AU770375B2 (en) 2004-02-19
ATE234830T1 (de) 2003-04-15
WO2000035908A1 (en) 2000-06-22
US6252086B1 (en) 2001-06-26
US6130239A (en) 2000-10-10
DE69906152T2 (de) 2004-02-12
EP1157019B1 (en) 2003-03-19

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