CO5251471A1 - Formulaciones orales para compuestos antitumorales y su proceso de produccion - Google Patents

Formulaciones orales para compuestos antitumorales y su proceso de produccion

Info

Publication number
CO5251471A1
CO5251471A1 CO00079673A CO00079673A CO5251471A1 CO 5251471 A1 CO5251471 A1 CO 5251471A1 CO 00079673 A CO00079673 A CO 00079673A CO 00079673 A CO00079673 A CO 00079673A CO 5251471 A1 CO5251471 A1 CO 5251471A1
Authority
CO
Colombia
Prior art keywords
pharmaceutically acceptable
production process
oral formulations
camptothecin derivative
antitumoral compounds
Prior art date
Application number
CO00079673A
Other languages
English (en)
Spanish (es)
Inventor
Lorena Muggetti
Alessandro Martini
Paola Civaroli
Christopher James
Original Assignee
Pharmacia And Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia And Upjohn Spa filed Critical Pharmacia And Upjohn Spa
Publication of CO5251471A1 publication Critical patent/CO5251471A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CO00079673A 1999-10-22 2000-10-19 Formulaciones orales para compuestos antitumorales y su proceso de produccion CO5251471A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9925127.4A GB9925127D0 (en) 1999-10-22 1999-10-22 Oral formulations for anti-tumor compounds

Publications (1)

Publication Number Publication Date
CO5251471A1 true CO5251471A1 (es) 2003-02-28

Family

ID=10863264

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00079673A CO5251471A1 (es) 1999-10-22 2000-10-19 Formulaciones orales para compuestos antitumorales y su proceso de produccion

Country Status (26)

Country Link
US (1) US7201913B1 (no)
EP (1) EP1223936A1 (no)
JP (1) JP2003512430A (no)
KR (1) KR100838097B1 (no)
CN (1) CN1198616C (no)
AR (1) AR031834A1 (no)
AU (1) AU784201B2 (no)
BR (1) BR0014902A (no)
CA (1) CA2387648A1 (no)
CO (1) CO5251471A1 (no)
CZ (1) CZ20021372A3 (no)
EA (1) EA008284B1 (no)
GB (1) GB9925127D0 (no)
HK (1) HK1048253B (no)
HU (1) HUP0202850A3 (no)
IL (2) IL149044A0 (no)
MX (1) MXPA02003904A (no)
MY (1) MY138106A (no)
NO (1) NO322782B1 (no)
NZ (1) NZ518398A (no)
PE (1) PE20010809A1 (no)
PL (1) PL356236A1 (no)
SK (1) SK5102002A3 (no)
TW (1) TWI233355B (no)
WO (1) WO2001030351A1 (no)
ZA (1) ZA200203042B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE344670T1 (de) * 2000-02-28 2006-11-15 Pfizer Entpr Sarl Synergistische kombination zur behandlung von kolorektalkarzinom
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
ITRM20030074A1 (it) * 2003-02-21 2004-08-22 Pharmacia Italia Spa Formulazioni semisolide a rilascio immediato intese
US7871632B2 (en) 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
GT200500310A (es) 2004-11-19 2006-06-19 Compuestos organicos
SA06270147B1 (ar) 2005-06-09 2009-12-22 نوفارتيس ايه جي عملية لتخليق 5-(مثيل–1h–إيميدازول–1-يل )–3-(ثلاثي فلـورو مثيل)–بنزامـين
US20070053869A1 (en) * 2005-09-02 2007-03-08 Yuichi Sugiyama Formulation and method for enhancement of gastrointestinal absorption of pharmaceutical agents
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) * 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
JP5297815B2 (ja) * 2007-01-26 2013-09-25 株式会社ポーラファルマ 医薬組成物
US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
TW200920347A (en) * 2007-07-16 2009-05-16 Poniard Pharmaceuticals Inc Oral formulations for picoplatin
CN101998851A (zh) * 2008-02-08 2011-03-30 帕纳德制药公司 吡铂和西妥昔单抗治疗结直肠癌的用途
HUP0900614A2 (en) * 2009-09-29 2011-05-30 Mate Dr Hidvegi Preparation comprising dehydrated, fermented material with amorphous crystaline structure and process for its production
JP2013512948A (ja) * 2009-12-08 2013-04-18 イル・ファ・カンパニー・リミテッド 20−O−β−D−グルコピラノシル−20(S)−プロトパナキサジオールを含む固体分散体
WO2014123899A1 (en) 2013-02-05 2014-08-14 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
CN110946836A (zh) * 2014-01-17 2020-04-03 昂科拉制药有限公司 用于治疗癌症的伊立替康的固体口服剂型
CN104524588A (zh) * 2014-12-05 2015-04-22 天津键凯科技有限公司 一种聚乙二醇修饰的喜树碱类衍生物的药物组合物及其制备方法
KR102293907B1 (ko) 2015-06-30 2021-08-26 한미약품 주식회사 이리노테칸 함유 경구용 고형제제 및 그 제조방법
KR102066402B1 (ko) * 2017-12-22 2020-01-15 대화제약 주식회사 이리노테칸 또는 그의 약제학적으로 허용가능한 염을 포함하는 경구투여용 약제학적 조성물
KR102185475B1 (ko) 2019-06-20 2020-12-02 대화제약 주식회사 이리노테칸 자유 염기를 포함하는 경구투여용 약학 조성물

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ236393A (en) * 1989-12-13 1992-05-26 Lilly Co Eli N-alkylated glycopeptide derivatives prepared from antibiotics a82846 series and pa-42867-a; pharmaceutical compositions
US5552156A (en) 1992-10-23 1996-09-03 Ohio State University Liposomal and micellular stabilization of camptothecin drugs
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
US5433951A (en) 1993-10-13 1995-07-18 Bristol-Myers Squibb Company Sustained release formulation containing captopril and method
IL115099A (en) * 1994-10-14 1999-04-11 Upjohn Co Lyophilizate of phospholipid complex of water insoluble camptothecins
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US5954998A (en) * 1995-05-25 1999-09-21 The Clorox Company Liquid peracid precursor colloidal dispersions: oil-core vesicles
ATE554750T1 (de) * 1997-03-05 2012-05-15 Sugen Inc Hydrophobe pharmazeutische wirkstoffe enthaltende zubereitungen
GB9711962D0 (en) * 1997-06-10 1997-08-06 Reckitt & Colmann Prod Ltd Therapeutically active compositions
JP5005847B2 (ja) * 1997-07-29 2012-08-22 ベーリンガー・インゲルハイム・インテルナツィオナール・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 親油性化合物用の自己乳化性処方
AR013261A1 (es) * 1997-08-01 2000-12-13 Smithkline Beecham Corp Formulaciones farmaceuticas para analogos de camptotecina en capsula de gelatina
FR2775188B1 (fr) * 1998-02-23 2001-03-09 Lipha Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption
CA2373931A1 (en) * 1999-05-17 2000-11-23 Richard Love Dfmo and celecoxib in combination for cancer chemoprevention and therapy
GB9918885D0 (en) * 1999-08-10 1999-10-13 Pharmacia & Upjohn Spa Pharmaceutical formulations in hydroxypropymethycellulose capsules

Also Published As

Publication number Publication date
IL149044A0 (en) 2002-11-10
MY138106A (en) 2009-04-30
AU784201B2 (en) 2006-02-23
KR20020045613A (ko) 2002-06-19
KR100838097B1 (ko) 2008-06-13
AU7661300A (en) 2001-05-08
CA2387648A1 (en) 2001-05-03
EP1223936A1 (en) 2002-07-24
MXPA02003904A (es) 2003-07-14
NZ518398A (en) 2004-01-30
TWI233355B (en) 2005-06-01
HUP0202850A3 (en) 2004-12-28
EA200200480A1 (ru) 2002-10-31
HK1048253B (zh) 2005-12-02
US7201913B1 (en) 2007-04-10
EA008284B1 (ru) 2007-04-27
HUP0202850A2 (hu) 2003-01-28
CZ20021372A3 (cs) 2002-09-11
GB9925127D0 (en) 1999-12-22
HK1048253A1 (en) 2003-03-28
NO322782B1 (no) 2006-12-11
NO20021834L (no) 2002-04-18
PE20010809A1 (es) 2001-08-01
WO2001030351A1 (en) 2001-05-03
PL356236A1 (en) 2004-06-28
JP2003512430A (ja) 2003-04-02
IL149044A (en) 2007-03-08
CN1382050A (zh) 2002-11-27
NO20021834D0 (no) 2002-04-18
SK5102002A3 (en) 2002-11-06
AR031834A1 (es) 2003-10-08
BR0014902A (pt) 2002-06-11
CN1198616C (zh) 2005-04-27
ZA200203042B (en) 2003-04-17

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