CO4940404A1 - PHARMACEUTICAL COMPOSITIONS - Google Patents

PHARMACEUTICAL COMPOSITIONS

Info

Publication number
CO4940404A1
CO4940404A1 CO98014254A CO98014254A CO4940404A1 CO 4940404 A1 CO4940404 A1 CO 4940404A1 CO 98014254 A CO98014254 A CO 98014254A CO 98014254 A CO98014254 A CO 98014254A CO 4940404 A1 CO4940404 A1 CO 4940404A1
Authority
CO
Colombia
Prior art keywords
fatty acid
mixture
pharmaceutical compositions
cyclosporine
cyclosporin
Prior art date
Application number
CO98014254A
Other languages
Spanish (es)
Inventor
Soo Woo Jong
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CO4940404A1 publication Critical patent/CO4940404A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Abstract

Una preparación que contiene ciclosporina, la cual comprende unacomposición que contiene: (1) ciclosporina como un ingrediente activo; (2) glicol de polietileno o carbonato de propileno o su mezcla; (3) uno o una mezcla de dos o más seleccionados a partir del grupo que consiste en un compuesto esterificado de ácido graso y alcohol primario, triglicéridos de ácido graso de cadena mediana, y monoglicérido de ácido graso como un componente de aceite, y (4) un tensoactivo que tiene un valor HLB (Equilibrio Hidrofílico-Lipofílico) de 8 a 17.A cyclosporin-containing preparation, which comprises a composition containing: (1) cyclosporine as an active ingredient; (2) polyethylene glycol or propylene carbonate or their mixture; (3) one or a mixture of two or more selected from the group consisting of an esterified compound of fatty acid and primary alcohol, medium chain fatty acid triglycerides, and fatty acid monoglyceride as an oil component, and ( 4) a surfactant that has an HLB (Hydrophilic-Lipophilic Balance) value of 8 to 17.

CO98014254A 1997-03-14 1998-03-13 PHARMACEUTICAL COMPOSITIONS CO4940404A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019970008750A KR19980073479A (en) 1997-03-14 1997-03-14 Cyclosporine-containing soft capsules

Publications (1)

Publication Number Publication Date
CO4940404A1 true CO4940404A1 (en) 2000-07-24

Family

ID=19499792

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98014254A CO4940404A1 (en) 1997-03-14 1998-03-13 PHARMACEUTICAL COMPOSITIONS

Country Status (24)

Country Link
EP (1) EP0969857A1 (en)
JP (1) JP3748573B2 (en)
KR (2) KR19980073479A (en)
CN (1) CN1161150C (en)
AR (1) AR012054A1 (en)
AU (1) AU741923B2 (en)
BR (1) BR9808324A (en)
CA (1) CA2283901A1 (en)
CO (1) CO4940404A1 (en)
CZ (1) CZ324399A3 (en)
DE (1) DE19882184T1 (en)
GB (1) GB2337703A (en)
HU (1) HUP0001515A3 (en)
ID (1) ID23531A (en)
IL (1) IL131703A0 (en)
MY (1) MY118614A (en)
NO (1) NO994436D0 (en)
PE (1) PE59499A1 (en)
PL (1) PL335729A1 (en)
RU (1) RU2185188C2 (en)
SK (1) SK123299A3 (en)
TR (1) TR199902229T2 (en)
WO (1) WO1998041225A1 (en)
ZA (1) ZA982117B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2380674B (en) * 1998-03-06 2003-05-28 Novartis Ag Emulsion preconcentrates containing cyclosporin or a macrolide
US7203158B2 (en) * 2000-12-06 2007-04-10 Matsushita Electric Industrial Co., Ltd. OFDM signal transmission system, portable terminal, and e-commerce system
GB0526419D0 (en) * 2005-12-23 2006-02-08 Cyclacel Ltd Formulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5603951A (en) * 1994-11-09 1997-02-18 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
KR0167613B1 (en) * 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 Cyclosporin-containing soft capsule compositions
SI9720010B (en) * 1996-06-19 2009-10-31 Novartis Ag Cyclosporin-containing soft capsule preparations
KR0183449B1 (en) * 1996-06-19 1999-05-01 한스 루돌프 하우스, 니콜 케르커 Cyclosporin-containing soft capsule preparations

Also Published As

Publication number Publication date
AU741923B2 (en) 2001-12-13
JP2000514831A (en) 2000-11-07
WO1998041225A1 (en) 1998-09-24
SK123299A3 (en) 2000-02-14
PL335729A1 (en) 2000-05-08
RU2185188C2 (en) 2002-07-20
MY118614A (en) 2004-12-31
TR199902229T2 (en) 1999-12-21
BR9808324A (en) 2000-05-16
CN1250378A (en) 2000-04-12
NO994436L (en) 1999-09-13
HUP0001515A3 (en) 2000-10-30
JP3748573B2 (en) 2006-02-22
KR20000075940A (en) 2000-12-26
CN1161150C (en) 2004-08-11
EP0969857A1 (en) 2000-01-12
PE59499A1 (en) 1999-07-05
IL131703A0 (en) 2001-03-19
AU6729398A (en) 1998-10-12
GB2337703A (en) 1999-12-01
AR012054A1 (en) 2000-09-27
CZ324399A3 (en) 1999-12-15
KR19980073479A (en) 1998-11-05
GB9921495D0 (en) 1999-11-17
ZA982117B (en) 1998-09-14
DE19882184T1 (en) 2000-02-10
NO994436D0 (en) 1999-09-13
ID23531A (en) 2000-04-27
CA2283901A1 (en) 1998-09-24
HUP0001515A2 (en) 2000-09-28

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