MY138975A - Novel preparation and administration form comprising an acid-labile active compound - Google Patents

Novel preparation and administration form comprising an acid-labile active compound

Info

Publication number
MY138975A
MY138975A MYPI20002403A MYPI20002403A MY138975A MY 138975 A MY138975 A MY 138975A MY PI20002403 A MYPI20002403 A MY PI20002403A MY PI20002403 A MYPI20002403 A MY PI20002403A MY 138975 A MY138975 A MY 138975A
Authority
MY
Malaysia
Prior art keywords
active compound
acid
administration form
mixture
labile active
Prior art date
Application number
MYPI20002403A
Inventor
Rango Dr Dietrich
Rudolf Dr Linder
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7910295&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY138975(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of MY138975A publication Critical patent/MY138975A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NOVEL ADMINISTRATION FORMS AND PREPARATIONS FOR ACID-LABILE ACTIVE COMPOUNDS ARE DESCRIBED. THE NOVEL ADMINISTRATION FORMS CONTAIN INDIVIDUAL ACTIVE COMPOUND UNITS, THE ACTIVE COMPOUND BEING PRESENT IN THE ACTIVE COMPOUND UNITS IN A MATRIX MADE OF A MIXTURE COMPRISING AT LEAST ONE FATTY ALCOHOL AND AT LEAST ONE SOLID PARAFIN, IN A MATRIX MADE OF A MIXTURE OF A TRIGLYCERIDE AND AT LEAST ONE SOLID PARAFFIN OR IN A MATRIX MADE OF A MIXTURE COMPRISING AT LEAST ONE FATTY ACID ESTER AND AT LEAST ONE SOLID PARAFFIN. IN PARTICULAR, THE ACTIVE COMPOUND UNITS ARE MICROSPHERES WHICH CAN BE PRODUCED BY PRILLING.
MYPI20002403A 1999-06-07 2000-05-30 Novel preparation and administration form comprising an acid-labile active compound MY138975A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19925710A DE19925710C2 (en) 1999-06-07 1999-06-07 New preparation and dosage form containing an acid labile proton pump inhibitor

Publications (1)

Publication Number Publication Date
MY138975A true MY138975A (en) 2009-08-28

Family

ID=7910295

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20002403A MY138975A (en) 1999-06-07 2000-05-30 Novel preparation and administration form comprising an acid-labile active compound

Country Status (6)

Country Link
AR (1) AR024310A1 (en)
CO (1) CO5160296A1 (en)
DE (1) DE19925710C2 (en)
MY (1) MY138975A (en)
PE (1) PE20010303A1 (en)
TW (1) TWI255720B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA80393C2 (en) 2000-12-07 2007-09-25 Алтана Фарма Аг Pharmaceutical preparation comprising an pde inhibitor dispersed on a matrix
PT1341524E (en) * 2000-12-07 2011-12-30 Nycomed Gmbh Pharmaceutical preparation in the form of a paste comprising an acid-labile active ingredient
US7357943B2 (en) 2000-12-07 2008-04-15 Nycomed Gmbh Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient
DE10061135C1 (en) * 2000-12-07 2002-11-07 Byk Gulden Lomberg Chem Fab Stable gel preparation for oral administration of acid-labile drug, especially proton pump inhibitor, comprises multiple drug units dispersed in gel base
DE10061136C1 (en) * 2000-12-07 2002-10-24 Byk Gulden Lomberg Chem Fab Stable, rapidly disintegrating tablets containing proton pump inhibitors, useful for treating elevated gastric secretion, comprising multiple drug units and auxiliaries including basic filler
DE10061138C1 (en) * 2000-12-07 2002-08-14 Byk Gulden Lomberg Chem Fab Pharmaceutical preparation in the form of a juice containing an acid-labile active ingredient
ATE541564T1 (en) * 2000-12-07 2012-02-15 Nycomed Gmbh QUICKLY DISRUPTING TABLET WITH AN ACID LABEL ACTIVE INGREDIENT
DE10061137B4 (en) * 2000-12-07 2016-10-06 Takeda Gmbh New pharmaceutical preparation
SE0101379D0 (en) 2001-04-18 2001-04-18 Diabact Ab Composition that inhibits gastric acid secretion
CN1596101A (en) 2001-09-28 2005-03-16 麦克内尔-Ppc股份有限公司 Fondant composition contained dosage forms
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CA2490142A1 (en) * 2002-07-03 2004-01-15 Abbott Laboratories Liquid dosage forms of proton pump inhibitors
DE10244129B4 (en) * 2002-09-23 2006-04-20 Iongate Biosciences Gmbh H + -K + -ATPase assay
SE0203065D0 (en) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
ME00524B (en) 2003-03-10 2011-10-10 Astrazeneca Ab Novel process for the preparation of roflumilast
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
CA2601250C (en) 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2725924C3 (en) * 1977-06-08 1980-11-06 Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau Process for the production of spherical particles from low-melting organic substances
DE3524572A1 (en) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K SOLID PHARMACEUTICAL FORMS FOR PERORAL USE CONTAINING 9-DEOXO-11-DEOXY-9,11- (IMINO (2- (2-METHOXYETHOXY) ETHYLIDEN) -OXY) - (9S) -ERYTHROMYCIN AND METHOD FOR THE PRODUCTION THEREOF
JP2681373B2 (en) * 1988-07-18 1997-11-26 塩野義製薬株式会社 Method for manufacturing sustained-release preparation

Also Published As

Publication number Publication date
AR024310A1 (en) 2002-09-25
DE19925710A1 (en) 2000-12-14
TWI255720B (en) 2006-06-01
PE20010303A1 (en) 2001-03-09
CO5160296A1 (en) 2002-05-30
DE19925710C2 (en) 2002-10-10

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