CO2024013848A2 - Enzimas escualeno-hopeno-ciclasa (shc) y variantes de enzimas - Google Patents

Enzimas escualeno-hopeno-ciclasa (shc) y variantes de enzimas

Info

Publication number
CO2024013848A2
CO2024013848A2 CONC2024/0013848A CO2024013848A CO2024013848A2 CO 2024013848 A2 CO2024013848 A2 CO 2024013848A2 CO 2024013848 A CO2024013848 A CO 2024013848A CO 2024013848 A2 CO2024013848 A2 CO 2024013848A2
Authority
CO
Colombia
Prior art keywords
shc
cyclase
squalene
enzymes
hose
Prior art date
Application number
CONC2024/0013848A
Other languages
English (en)
Spanish (es)
Inventor
Eric Eichhorn
Bernhard Hauer
Andreas Schneider
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of CO2024013848A2 publication Critical patent/CO2024013848A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/0069—Heterocyclic compounds
    • C11B9/0073—Heterocyclic compounds containing only O or S as heteroatoms
    • C11B9/0076—Heterocyclic compounds containing only O or S as heteroatoms the hetero rings containing less than six atoms
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/50—Perfumes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017—Squalene--hopene cyclase (5.4.99.17)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01048—Histone acetyltransferase (2.3.1.48)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
CONC2024/0013848A 2022-03-17 2024-10-15 Enzimas escualeno-hopeno-ciclasa (shc) y variantes de enzimas CO2024013848A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22162848 2022-03-17
EP22168607 2022-04-14
PCT/EP2023/056842 WO2023175123A1 (en) 2022-03-17 2023-03-17 Shc enzymes and enzyme variants

Publications (1)

Publication Number Publication Date
CO2024013848A2 true CO2024013848A2 (es) 2025-03-27

Family

ID=85569892

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2024/0013848A CO2024013848A2 (es) 2022-03-17 2024-10-15 Enzimas escualeno-hopeno-ciclasa (shc) y variantes de enzimas

Country Status (8)

Country Link
US (1) US20260043058A1 (https=)
EP (1) EP4493685A1 (https=)
JP (1) JP2025509737A (https=)
CN (1) CN119137269A (https=)
CO (1) CO2024013848A2 (https=)
IL (1) IL315567A (https=)
MX (1) MX2024011115A (https=)
WO (1) WO2023175123A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024112870A1 (en) * 2022-11-23 2024-05-30 Conagen Inc. Conversion of homofarnesol to ambroxide
EP4724593A2 (en) * 2023-06-12 2026-04-15 Firmenich SA Polypeptides for preparing terpenoid compounds
EP4563705A1 (en) * 2023-11-30 2025-06-04 Universität Stuttgart Biocatalytic stereocontrolled production of 1-(r)-cis-pmd

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19649655A1 (de) 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung
DE19960106A1 (de) 1999-12-14 2001-06-21 Haarmann & Reimer Gmbh Enzyme und Gene für die Herstellung von Vanillin
JP5236233B2 (ja) 2007-09-04 2013-07-17 花王株式会社 （−）−アンブロキサンの製造方法
WO2010139719A2 (de) 2009-06-05 2010-12-09 Basf Se Biokatalytische herstellung von ambroxan
EP4112727A3 (de) 2010-11-17 2023-03-15 Basf Se Verfahren zur biokatalytischen cyclisierung von terpenen und darin einsetzbare cyclase-mutanten
WO2013156398A1 (de) 2012-04-16 2013-10-24 Basf Se Verbessertes verfahren zur herstellung von (3e, 7e)-homofarnesol
US20130273619A1 (en) 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
GB201507207D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201618090D0 (en) 2016-10-26 2016-12-07 Givaudan Sa Product
JP2020508651A (ja) 2017-02-24 2020-03-26 インターナショナル フレーバーズ アンド フラグランシズ インコーポレイテッド スクアレンホペンシクラーゼ、およびアンブロキサンを生成するためのその使用
GB201917694D0 (en) 2019-12-04 2020-01-15 Givaudan Sa Enzyme mediated process
GB201917688D0 (en) 2019-12-04 2020-01-15 Givaudan Sa SHC enzymes and enzyme variants
GB202005468D0 (en) 2020-04-15 2020-05-27 Givaudan Sa Enzyme-media process
GB202011823D0 (en) 2020-07-30 2020-09-16 Givaudan Sa Method
MX2023005851A (es) * 2020-11-18 2023-08-16 Univ Stuttgart Monociclizacion enzimatica de monoterpenoides aciclicos.

Also Published As

Publication number Publication date
JP2025509737A (ja) 2025-04-11
IL315567A (en) 2024-11-01
US20260043058A1 (en) 2026-02-12
EP4493685A1 (en) 2025-01-22
WO2023175123A1 (en) 2023-09-21
MX2024011115A (es) 2024-09-18
CN119137269A (zh) 2024-12-13

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