JP2025509737A - Ｓｈｃ酵素および酵素バリアント - Google Patents

Ｓｈｃ酵素および酵素バリアント Download PDF

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Publication number
JP2025509737A
JP2025509737A JP2024555120A JP2024555120A JP2025509737A JP 2025509737 A JP2025509737 A JP 2025509737A JP 2024555120 A JP2024555120 A JP 2024555120A JP 2024555120 A JP2024555120 A JP 2024555120A JP 2025509737 A JP2025509737 A JP 2025509737A
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JP
Japan
Prior art keywords
seq
shc
amino acid
acid sequence
hac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2024555120A
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English (en)
Japanese (ja)
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JP2025509737A5 (https=
Inventor
アイヒホルン，エリック
ハウアー，ベルンハルト
シュナイダー，アンドレアス
Original Assignee
ジボダン エス エー
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Publication date
Application filed by ジボダン エス エー filed Critical ジボダン エス エー
Publication of JP2025509737A publication Critical patent/JP2025509737A/ja
Publication of JP2025509737A5 publication Critical patent/JP2025509737A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/0069—Heterocyclic compounds
    • C11B9/0073—Heterocyclic compounds containing only O or S as heteroatoms
    • C11B9/0076—Heterocyclic compounds containing only O or S as heteroatoms the hetero rings containing less than six atoms
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/50—Perfumes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017—Squalene--hopene cyclase (5.4.99.17)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01048—Histone acetyltransferase (2.3.1.48)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
JP2024555120A 2022-03-17 2023-03-17 Ｓｈｃ酵素および酵素バリアント Pending JP2025509737A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP22162848.0 2022-03-17
EP22162848 2022-03-17
EP22168607 2022-04-14
EP22168607.4 2022-04-14
PCT/EP2023/056842 WO2023175123A1 (en) 2022-03-17 2023-03-17 Shc enzymes and enzyme variants

Publications (2)

Publication Number Publication Date
JP2025509737A true JP2025509737A (ja) 2025-04-11
JP2025509737A5 JP2025509737A5 (https=) 2026-02-13

Family

ID=85569892

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024555120A Pending JP2025509737A (ja) 2022-03-17 2023-03-17 Ｓｈｃ酵素および酵素バリアント

Country Status (8)

Country Link
US (1) US20260043058A1 (https=)
EP (1) EP4493685A1 (https=)
JP (1) JP2025509737A (https=)
CN (1) CN119137269A (https=)
CO (1) CO2024013848A2 (https=)
IL (1) IL315567A (https=)
MX (1) MX2024011115A (https=)
WO (1) WO2023175123A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024112870A1 (en) * 2022-11-23 2024-05-30 Conagen Inc. Conversion of homofarnesol to ambroxide
EP4724593A2 (en) * 2023-06-12 2026-04-15 Firmenich SA Polypeptides for preparing terpenoid compounds
EP4563705A1 (en) * 2023-11-30 2025-06-04 Universität Stuttgart Biocatalytic stereocontrolled production of 1-(r)-cis-pmd

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19649655A1 (de) 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung
DE19960106A1 (de) 1999-12-14 2001-06-21 Haarmann & Reimer Gmbh Enzyme und Gene für die Herstellung von Vanillin
JP5236233B2 (ja) 2007-09-04 2013-07-17 花王株式会社 （−）−アンブロキサンの製造方法
WO2010139719A2 (de) 2009-06-05 2010-12-09 Basf Se Biokatalytische herstellung von ambroxan
EP4112727A3 (de) 2010-11-17 2023-03-15 Basf Se Verfahren zur biokatalytischen cyclisierung von terpenen und darin einsetzbare cyclase-mutanten
WO2013156398A1 (de) 2012-04-16 2013-10-24 Basf Se Verbessertes verfahren zur herstellung von (3e, 7e)-homofarnesol
US20130273619A1 (en) 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
GB201507207D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201618090D0 (en) 2016-10-26 2016-12-07 Givaudan Sa Product
JP2020508651A (ja) 2017-02-24 2020-03-26 インターナショナル フレーバーズ アンド フラグランシズ インコーポレイテッド スクアレンホペンシクラーゼ、およびアンブロキサンを生成するためのその使用
GB201917694D0 (en) 2019-12-04 2020-01-15 Givaudan Sa Enzyme mediated process
GB201917688D0 (en) 2019-12-04 2020-01-15 Givaudan Sa SHC enzymes and enzyme variants
GB202005468D0 (en) 2020-04-15 2020-05-27 Givaudan Sa Enzyme-media process
GB202011823D0 (en) 2020-07-30 2020-09-16 Givaudan Sa Method
MX2023005851A (es) * 2020-11-18 2023-08-16 Univ Stuttgart Monociclizacion enzimatica de monoterpenoides aciclicos.

Also Published As

Publication number Publication date
CO2024013848A2 (es) 2025-03-27
IL315567A (en) 2024-11-01
US20260043058A1 (en) 2026-02-12
EP4493685A1 (en) 2025-01-22
WO2023175123A1 (en) 2023-09-21
MX2024011115A (es) 2024-09-18
CN119137269A (zh) 2024-12-13

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