CO2022011666A2 - Empleo del compuesto en la prevención y/o el tratamiento de infecciones patógenas en animales - Google Patents

Empleo del compuesto en la prevención y/o el tratamiento de infecciones patógenas en animales

Info

Publication number
CO2022011666A2
CO2022011666A2 CONC2022/0011666A CO2022011666A CO2022011666A2 CO 2022011666 A2 CO2022011666 A2 CO 2022011666A2 CO 2022011666 A CO2022011666 A CO 2022011666A CO 2022011666 A2 CO2022011666 A2 CO 2022011666A2
Authority
CO
Colombia
Prior art keywords
compound
animals
prevention
treatment
coronaviruses
Prior art date
Application number
CONC2022/0011666A
Other languages
English (en)
Inventor
Di Kang
Danni Li
Xingyu Lin
Tingting Lu
Original Assignee
Felicamed Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Felicamed Biotechnology Co Ltd filed Critical Felicamed Biotechnology Co Ltd
Publication of CO2022011666A2 publication Critical patent/CO2022011666A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención da a conocer la aplicación de un compuesto para prevenir y/o tratar la infección patógena en los animales. Se trata del compuesto 4-(3-{2-amino-5-[2-(1-methyl-piperidin-4-yl)-thiazol-5-yl]-pyridin-3-yloxymethyl}-phenyl)-2-methylbut-3-yn-2-ol el cual tiene la estructura de la fórmula I que aparece a continuación. El compuesto puede utilizarse para tratar de forma eficaz las enfermedades (por ejemplo, la peritonitis infecciosa felina) provocadas por la infección de patógenos animales (especialmente los virus, como los coronavirus), y para aumentar la supervivencia de los animales, y puede tener un mayor valor comercial y perspectivas de aplicación en el ámbito de los medicamentos veterinarios contra los patógenos (especialmente los virus, como los coronavirus).
CONC2022/0011666A 2020-06-16 2022-08-19 Empleo del compuesto en la prevención y/o el tratamiento de infecciones patógenas en animales CO2022011666A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202010547186.8A CN113797198B (zh) 2020-06-16 2020-06-16 一种化合物在预防和/或治疗动物的病原体感染中的应用
PCT/CN2021/099650 WO2021254265A1 (zh) 2020-06-16 2021-06-11 一种化合物在预防和/或治疗动物的病原体感染中的应用

Publications (1)

Publication Number Publication Date
CO2022011666A2 true CO2022011666A2 (es) 2022-08-30

Family

ID=78892522

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2022/0011666A CO2022011666A2 (es) 2020-06-16 2022-08-19 Empleo del compuesto en la prevención y/o el tratamiento de infecciones patógenas en animales

Country Status (12)

Country Link
US (1) US20230097009A1 (es)
EP (1) EP4094763B1 (es)
JP (1) JP7442662B2 (es)
KR (1) KR20220129592A (es)
CN (2) CN113797198B (es)
AU (1) AU2021291983B2 (es)
BR (1) BR112022016727A2 (es)
CA (1) CA3168377A1 (es)
CO (1) CO2022011666A2 (es)
MX (1) MX2022010020A (es)
WO (1) WO2021254265A1 (es)
ZA (1) ZA202213500B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113797202B (zh) * 2020-06-16 2024-06-28 珠海宇繁生物科技有限责任公司 Hpk1激酶抑制剂在预防和/或治疗动物的病原体感染中的应用
CN114437058A (zh) * 2020-10-30 2022-05-06 珠海宇繁生物科技有限责任公司 氘代hpk1激酶抑制剂及其制备方法和应用
CN114839378B (zh) * 2022-07-04 2022-09-06 山东康华生物医疗科技股份有限公司 一种猫疱疹和猫杯状病毒联合检测试剂盒
CN114966020B (zh) * 2022-07-13 2022-09-27 北京市农林科学院 检测牛传染性鼻气管炎病毒的胶体金试纸条及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111527084B (zh) * 2017-11-06 2023-07-18 百时美施贵宝公司 可用作hpk1抑制剂的异呋喃酮化合物
CN110372664A (zh) * 2018-04-13 2019-10-25 华东理工大学 选择性jak2抑制剂及其应用
CN110396087A (zh) * 2018-04-25 2019-11-01 珠海宇繁生物科技有限责任公司 Hpk1激酶抑制剂、制备方法及其应用
WO2019206049A1 (en) * 2018-04-25 2019-10-31 Zhuhai Yufan Biotechnologies Co., Ltd Hpk1 inhibitors, preparation method and application thereof
CN110063954B (zh) * 2019-04-10 2021-08-06 华中农业大学 Fhpi在制备治疗猫传染性腹膜炎药物中的应用
CN110215456A (zh) * 2019-06-25 2019-09-10 华中农业大学 一种由gc376与gs-441524组成的猫冠状病毒抑制剂组合物
CN113797202B (zh) * 2020-06-16 2024-06-28 珠海宇繁生物科技有限责任公司 Hpk1激酶抑制剂在预防和/或治疗动物的病原体感染中的应用

Also Published As

Publication number Publication date
ZA202213500B (en) 2023-07-26
JP2023525430A (ja) 2023-06-16
EP4094763A1 (en) 2022-11-30
MX2022010020A (es) 2022-10-10
AU2021291983A1 (en) 2022-09-08
CN113797198B (zh) 2023-11-28
CN113797198A (zh) 2021-12-17
CA3168377A1 (en) 2021-12-23
EP4094763A4 (en) 2023-04-26
KR20220129592A (ko) 2022-09-23
US20230097009A1 (en) 2023-03-30
AU2021291983B2 (en) 2024-01-18
EP4094763B1 (en) 2024-09-18
BR112022016727A2 (pt) 2022-12-27
JP7442662B2 (ja) 2024-03-04
CN117338775A (zh) 2024-01-05
WO2021254265A1 (zh) 2021-12-23

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