CO2021013244A2 - Composición farmacéutica acuosa de anticuerpo anti-il17a y su uso - Google Patents

Composición farmacéutica acuosa de anticuerpo anti-il17a y su uso

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Publication number
CO2021013244A2
CO2021013244A2 CONC2021/0013244A CO2021013244A CO2021013244A2 CO 2021013244 A2 CO2021013244 A2 CO 2021013244A2 CO 2021013244 A CO2021013244 A CO 2021013244A CO 2021013244 A2 CO2021013244 A2 CO 2021013244A2
Authority
CO
Colombia
Prior art keywords
pharmaceutical composition
il17a antibody
aqueous pharmaceutical
il17a
variable domain
Prior art date
Application number
CONC2021/0013244A
Other languages
English (en)
Inventor
Roman Alekseevich Ivanov
Dmitry Valentinovich Morozov
Ekaterina Valerevna Cherniaeva
Ekaterina Aleksandrovna Lomkova
Antonina Vasilevna Artemeva
Anna Viktorovna Eremeeva
Anastasiya Mikhajlovna Ryakhovskaya
Viktoriia Olegovna Shitikova
Aleksandr Olegovich Iakovlev
Original Assignee
Biocad Joint Stock Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocad Joint Stock Co filed Critical Biocad Joint Stock Co
Publication of CO2021013244A2 publication Critical patent/CO2021013244A2/es

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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
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    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
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    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
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Abstract

Esta divulgación se refiere a composiciones acuosas de anticuerpos anti-IL17a y, particularmente, a composiciones acuosas de anticuerpos anti-IL17a con un dominio variable VHH y un dominio variable VL. Estas composiciones pueden ser utilizadas como agentes medicinales para tratar enfermedades mediadas por IL-17А.
CONC2021/0013244A 2019-04-02 2021-10-01 Composición farmacéutica acuosa de anticuerpo anti-il17a y su uso CO2021013244A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2019109641A RU2754760C2 (ru) 2019-04-02 2019-04-02 Водная фармацевтическая композиция анти-il17a антитела и ее применение
PCT/RU2020/050065 WO2020204765A1 (en) 2019-04-02 2020-04-02 Aqueous pharmaceutical composition of an anti-il17a antibody and use thereof

Publications (1)

Publication Number Publication Date
CO2021013244A2 true CO2021013244A2 (es) 2021-10-20

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Application Number Title Priority Date Filing Date
CONC2021/0013244A CO2021013244A2 (es) 2019-04-02 2021-10-01 Composición farmacéutica acuosa de anticuerpo anti-il17a y su uso

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US (1) US20220372127A1 (es)
EP (1) EP3946454A4 (es)
JP (2) JP2022528119A (es)
KR (1) KR20220010483A (es)
CN (1) CN110898220B (es)
AR (1) AR118571A1 (es)
AU (1) AU2020255987A1 (es)
BR (1) BR112021019903A2 (es)
CA (1) CA3135357A1 (es)
CL (1) CL2021002574A1 (es)
CO (1) CO2021013244A2 (es)
CR (1) CR20210507A (es)
EC (1) ECSP21074141A (es)
IL (1) IL286867A (es)
JO (1) JOP20210269A1 (es)
MA (1) MA54663A1 (es)
MX (1) MX2021011995A (es)
PE (1) PE20212158A1 (es)
RU (1) RU2754760C2 (es)
SG (1) SG11202110848TA (es)
TW (2) TWI844034B (es)
UY (1) UY38629A (es)
WO (1) WO2020204765A1 (es)
ZA (1) ZA202107587B (es)

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CN115746132B (zh) * 2021-09-03 2023-09-08 三优生物医药(上海)有限公司 抗il-17a抗体及其用途
CN116510006A (zh) * 2022-01-31 2023-08-01 拜奥卡德联合股份公司 抗trbv9抗体的药物组合物及其用途
CN116593718B (zh) * 2023-07-18 2023-09-15 军科正源(北京)药物研究有限责任公司 用于检测司库奇尤单抗抗药性抗体的试剂
CN117820475B (zh) * 2023-12-21 2024-10-29 北京贝来生物科技有限公司 针对il-17a的新型纳米抗体、药物、制备、方法及应用
CN118078988A (zh) * 2024-04-19 2024-05-28 正大天晴药业集团南京顺欣制药有限公司 包含靶向il-17a的抗体药物组合物

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CN1671741A (zh) * 2002-06-21 2005-09-21 拜奥根Idec公司 浓缩抗体的缓冲剂制剂及其使用方法
RU2007133661A (ru) * 2005-03-08 2009-03-20 Фармация Энд Апджон Компани Ллс (Us) КОМПОЗИЦИИ АНТИТЕЛ К MAdCAM
US11433029B2 (en) * 2013-03-15 2022-09-06 Takeda Pharmaceutical Company Limited Formulation of an antibody and use thereof
RU2577228C2 (ru) * 2014-03-14 2016-03-10 Закрытое Акционерное Общество "Биокад" Анти-il-17-антитела, способ их получения и способ применения
RU2609627C2 (ru) * 2014-09-26 2017-02-02 Закрытое Акционерное Общество "Биокад" Высокоаффинные и агрегационно стабильные антитела на основе вариабельных доменов vl и производного vhh
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US20170360929A1 (en) * 2014-12-23 2017-12-21 Pfizer Inc. Stable aqueous antibody formulation for anti tnf alpha antibodies
SG11201706505PA (en) * 2015-02-13 2017-09-28 Sanofi Sa Stable liquid formulation for monoclonal antibodies
PL3263132T3 (pl) * 2015-02-27 2024-04-15 Chugai Seiyaku Kabushiki Kaisha Kompozycja do leczenia chorób związanych z il-6
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TW202037365A (zh) 2020-10-16
TWI797400B (zh) 2023-04-01
AR118571A1 (es) 2021-10-20
TW202237065A (zh) 2022-10-01
CL2021002574A1 (es) 2022-04-29
CN110898220A (zh) 2020-03-24
ZA202107587B (en) 2022-12-21
MX2021011995A (es) 2021-11-12
SG11202110848TA (en) 2021-10-28
US20220372127A1 (en) 2022-11-24
BR112021019903A2 (pt) 2021-12-07
IL286867A (en) 2021-12-01
RU2754760C2 (ru) 2021-09-07
WO2020204765A1 (en) 2020-10-08
JP2024119827A (ja) 2024-09-03
CA3135357A1 (en) 2020-10-08
JP2022528119A (ja) 2022-06-08
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RU2019109641A3 (es) 2021-03-19
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UY38629A (es) 2020-10-30
AU2020255987A1 (en) 2021-10-28
CN110898220B (zh) 2024-08-13
TWI844034B (zh) 2024-06-01
EP3946454A4 (en) 2023-11-15
ECSP21074141A (es) 2021-11-30
MA54663A1 (fr) 2022-09-30
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