AR118571A1 - Composición farmacéutica acuosa de anticuerpo anti-il17a - Google Patents

Composición farmacéutica acuosa de anticuerpo anti-il17a

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Publication number
AR118571A1
AR118571A1 ARP200100927A ARP200100927A AR118571A1 AR 118571 A1 AR118571 A1 AR 118571A1 AR P200100927 A ARP200100927 A AR P200100927A AR P200100927 A ARP200100927 A AR P200100927A AR 118571 A1 AR118571 A1 AR 118571A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
il17a antibody
il17a
aqueous pharmaceutical
aqueous
Prior art date
Application number
ARP200100927A
Other languages
English (en)
Inventor
Dmitry Valentinovich Morozov
Aleksandr Olegovich Iakovlev
Viktoriia Olegovna Shitikova
Anastasiya Mikhajlovna Ryakhovskaya
Roman Alekseevich Ivanov
Anna Viktorovna Eremeeva
Antonina Vasilevna Artemeva
Ekaterina Aleksandrovna Lomkova
Ekaterina Valerevna Cherniaeva
Original Assignee
Joint Stock Company “Biocad”
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Joint Stock Company “Biocad” filed Critical Joint Stock Company “Biocad”
Publication of AR118571A1 publication Critical patent/AR118571A1/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Mycology (AREA)
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Abstract

Esta divulgación se refiere a composiciones acuosas de anticuerpos anti-IL17a y, particularmente, a composiciones acuosas de anticuerpos anti-IL17a con un dominio variable VHH y un dominio variable VL. Estas composiciones pueden ser utilizadas como agentes medicinales para tratar enfermedades mediadas por IL-17A. Reivindicación 1: Una composición farmacéutica acuosa para inhibir la actividad de la proteína IL17a caracterizada por que comprende: una cantidad farmacéuticamente eficaz de un anticuerpo anti-IL17a que comprende un dominio derivado de VHH y un dominio VL variable; un agente tampón a base de histidina; y una cantidad eficaz de un alcohol a base de azúcar como un agente osmótico. Reivindicación 3: Una composición farmacéutica acuosa según reivindicación 1, caracterizada por que dicho anticuerpo anti-IL17a es Netakimab.
ARP200100927A 2019-04-02 2020-04-02 Composición farmacéutica acuosa de anticuerpo anti-il17a AR118571A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2019109641A RU2754760C2 (ru) 2019-04-02 2019-04-02 Водная фармацевтическая композиция анти-il17a антитела и ее применение

Publications (1)

Publication Number Publication Date
AR118571A1 true AR118571A1 (es) 2021-10-20

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ARP200100927A AR118571A1 (es) 2019-04-02 2020-04-02 Composición farmacéutica acuosa de anticuerpo anti-il17a

Country Status (24)

Country Link
US (1) US20220372127A1 (es)
EP (1) EP3946454A4 (es)
JP (1) JP2022528119A (es)
KR (1) KR20220010483A (es)
CN (1) CN110898220A (es)
AR (1) AR118571A1 (es)
AU (1) AU2020255987A1 (es)
BR (1) BR112021019903A2 (es)
CA (1) CA3135357A1 (es)
CL (1) CL2021002574A1 (es)
CO (1) CO2021013244A2 (es)
CR (1) CR20210507A (es)
EC (1) ECSP21074141A (es)
IL (1) IL286867A (es)
JO (1) JOP20210269A1 (es)
MA (1) MA54663A1 (es)
MX (1) MX2021011995A (es)
PE (1) PE20212158A1 (es)
RU (1) RU2754760C2 (es)
SG (1) SG11202110848TA (es)
TW (2) TW202237065A (es)
UY (1) UY38629A (es)
WO (1) WO2020204765A1 (es)
ZA (1) ZA202107587B (es)

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Publication number Priority date Publication date Assignee Title
CN115746132B (zh) * 2021-09-03 2023-09-08 三优生物医药(上海)有限公司 抗il-17a抗体及其用途
CN116510006A (zh) * 2022-01-31 2023-08-01 拜奥卡德联合股份公司 抗trbv9抗体的药物组合物及其用途
CN116593718B (zh) * 2023-07-18 2023-09-15 军科正源（北京）药物研究有限责任公司 用于检测司库奇尤单抗抗药性抗体的试剂

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US11433029B2 (en) * 2013-03-15 2022-09-06 Takeda Pharmaceutical Company Limited Formulation of an antibody and use thereof
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JP2018507202A (ja) * 2015-02-13 2018-03-15 サノフイ モノクローナル抗体のための安定的な液体製剤
KR101892883B1 (ko) * 2015-02-27 2018-10-05 추가이 세이야쿠 가부시키가이샤 Il-6 관련 질환 치료용 조성물
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CN110898220A (zh) 2020-03-24
CR20210507A (es) 2021-11-17
RU2019109641A (ru) 2020-10-02
CA3135357A1 (en) 2020-10-08
US20220372127A1 (en) 2022-11-24
RU2754760C2 (ru) 2021-09-07
IL286867A (en) 2021-12-01
EP3946454A1 (en) 2022-02-09
TW202037365A (zh) 2020-10-16
AU2020255987A1 (en) 2021-10-28
MA54663A1 (fr) 2022-09-30
JP2022528119A (ja) 2022-06-08
JOP20210269A1 (ar) 2023-01-30
CL2021002574A1 (es) 2022-04-29
TW202237065A (zh) 2022-10-01
CO2021013244A2 (es) 2021-10-20
KR20220010483A (ko) 2022-01-25
WO2020204765A1 (en) 2020-10-08
ECSP21074141A (es) 2021-11-30
EP3946454A4 (en) 2023-11-15
TWI797400B (zh) 2023-04-01
BR112021019903A2 (pt) 2021-12-07
ZA202107587B (en) 2022-12-21
PE20212158A1 (es) 2021-11-09
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RU2019109641A3 (es) 2021-03-19
MX2021011995A (es) 2021-11-12

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