CO2018012113A2 - Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina - Google Patents
Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidinaInfo
- Publication number
- CO2018012113A2 CO2018012113A2 CONC2018/0012113A CO2018012113A CO2018012113A2 CO 2018012113 A2 CO2018012113 A2 CO 2018012113A2 CO 2018012113 A CO2018012113 A CO 2018012113A CO 2018012113 A2 CO2018012113 A2 CO 2018012113A2
- Authority
- CO
- Colombia
- Prior art keywords
- octenidine
- preservative
- compositions containing
- dose compositions
- antimicrobial polyamide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/10011—Circoviridae
- C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Abstract
RESUMEN DE LA INVENCIÓN La presente invención se relaciona a conservadores no mercuriales, que incluyen polímeros de poliamida antimicrobiana y octenidina, y a métodos de uso de los mismos para producir formulaciones de múltiples dosis que contienen conservador. Las formulaciones de múltiples dosis que contienen conservador exhiben resistencia a uno o más microorganismos contaminantes, y tienen propiedades ventajosas con respecto a la estabilidad a largo plazo de ingredientes activos biológicos y de molécula pequeña.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662322258P | 2016-04-14 | 2016-04-14 | |
PCT/US2017/027491 WO2017180916A1 (en) | 2016-04-14 | 2017-04-13 | Multi-dose compositions containing an antimicrobial polyamide or octenidine preservative |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2018012113A2 true CO2018012113A2 (es) | 2019-02-08 |
Family
ID=59215875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2018/0012113A CO2018012113A2 (es) | 2016-04-14 | 2018-11-09 | Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina |
Country Status (14)
Country | Link |
---|---|
US (1) | US10583154B2 (es) |
EP (1) | EP3442587B1 (es) |
JP (1) | JP7089479B2 (es) |
KR (1) | KR20180129949A (es) |
CN (1) | CN109310776B (es) |
AU (1) | AU2017248674B2 (es) |
BR (1) | BR112018071125A8 (es) |
CA (1) | CA3020634A1 (es) |
CL (1) | CL2018002919A1 (es) |
CO (1) | CO2018012113A2 (es) |
EA (1) | EA039370B1 (es) |
ES (1) | ES2898798T3 (es) |
MX (1) | MX2018012477A (es) |
WO (1) | WO2017180916A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20200383932A1 (en) * | 2019-06-05 | 2020-12-10 | The Florida International University Board Of Trustees | Biotherapy for viral infections using biopolymer based micro/nanogels |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK590288D0 (da) | 1988-10-24 | 1988-10-24 | Symbicom Ab | Kemiske forbindelser |
US2909462A (en) | 1955-12-08 | 1959-10-20 | Bristol Myers Co | Acrylic acid polymer laxative compositions |
US5777095A (en) | 1988-10-24 | 1998-07-07 | Symbicom Aktiebolag | Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90 |
ATE292980T1 (de) | 1996-10-11 | 2005-04-15 | Univ California | Immunostimulierende oligonucleotidekonjugate |
ATE470434T1 (de) * | 1997-02-06 | 2010-06-15 | Merck Sharp & Dohme | Thimerosal-freie konservierungsmittel für impfstoffe |
US6368603B1 (en) | 1997-03-05 | 2002-04-09 | Merial Limited | Lyme combination compositions and uses |
AUPP584298A0 (en) | 1998-09-14 | 1998-10-08 | Starpharma Limited | Antimicrobial and antiparasitic agents |
RU2195269C2 (ru) * | 2001-02-14 | 2002-12-27 | Общество с ограниченной ответственностью "МДТ" | Витаминно-минеральный комплекс |
DE10205883A1 (de) | 2002-02-13 | 2003-08-21 | Schuelke & Mayr Gmbh | Wässriges Antiseptikum auf Basis von Bispyridiniumalkanen |
MXPA06000942A (es) | 2003-07-24 | 2006-03-30 | Merial Ltd | Nuevas formulaciones de vacunas. |
DE102005045145A1 (de) | 2005-09-15 | 2007-03-29 | Schülke & Mayr GmbH | Verwendung von Octenidindihydrochlorid in halbfesten Zubereitungen |
CN101366945A (zh) * | 2008-08-21 | 2009-02-18 | 浙江卫信生物药业有限公司 | 不含甲醛和硫柳汞的吸附白喉疫苗的配制方法 |
KR102471356B1 (ko) * | 2010-06-01 | 2022-11-28 | 노파르티스 아게 | 동결건조하지 않는 인플루엔자 백신 항원의 농축 |
HUE048398T2 (hu) | 2010-06-04 | 2020-07-28 | Wyeth Llc | Vakcinakészítmények |
EA030750B1 (ru) | 2013-03-15 | 2018-09-28 | Мериал, Инк. | Противомикробная полиамидная композиция и способ лечения мастита |
-
2017
- 2017-04-13 CN CN201780035829.7A patent/CN109310776B/zh active Active
- 2017-04-13 JP JP2018554321A patent/JP7089479B2/ja active Active
- 2017-04-13 EA EA201892330A patent/EA039370B1/ru unknown
- 2017-04-13 KR KR1020187033037A patent/KR20180129949A/ko not_active Application Discontinuation
- 2017-04-13 EP EP17733091.7A patent/EP3442587B1/en active Active
- 2017-04-13 AU AU2017248674A patent/AU2017248674B2/en active Active
- 2017-04-13 MX MX2018012477A patent/MX2018012477A/es unknown
- 2017-04-13 CA CA3020634A patent/CA3020634A1/en active Pending
- 2017-04-13 WO PCT/US2017/027491 patent/WO2017180916A1/en active Application Filing
- 2017-04-13 BR BR112018071125A patent/BR112018071125A8/pt active Search and Examination
- 2017-04-13 ES ES17733091T patent/ES2898798T3/es active Active
- 2017-04-13 US US15/487,323 patent/US10583154B2/en active Active
-
2018
- 2018-10-12 CL CL2018002919A patent/CL2018002919A1/es unknown
- 2018-11-09 CO CONC2018/0012113A patent/CO2018012113A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
KR20180129949A (ko) | 2018-12-05 |
US20170296577A1 (en) | 2017-10-19 |
CL2018002919A1 (es) | 2019-01-18 |
EP3442587B1 (en) | 2021-08-18 |
BR112018071125A8 (pt) | 2022-06-28 |
CN109310776A (zh) | 2019-02-05 |
AU2017248674A1 (en) | 2018-11-01 |
EA039370B1 (ru) | 2022-01-19 |
JP7089479B2 (ja) | 2022-06-22 |
JP2019513793A (ja) | 2019-05-30 |
CN109310776B (zh) | 2022-02-11 |
EP3442587A1 (en) | 2019-02-20 |
MX2018012477A (es) | 2019-03-07 |
WO2017180916A1 (en) | 2017-10-19 |
AU2017248674B2 (en) | 2021-04-01 |
EA201892330A1 (ru) | 2019-03-29 |
BR112018071125A2 (pt) | 2019-02-05 |
ES2898798T3 (es) | 2022-03-08 |
CA3020634A1 (en) | 2017-10-19 |
US10583154B2 (en) | 2020-03-10 |
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