CL2018002919A1 - Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina. - Google Patents

Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina.

Info

Publication number
CL2018002919A1
CL2018002919A1 CL2018002919A CL2018002919A CL2018002919A1 CL 2018002919 A1 CL2018002919 A1 CL 2018002919A1 CL 2018002919 A CL2018002919 A CL 2018002919A CL 2018002919 A CL2018002919 A CL 2018002919A CL 2018002919 A1 CL2018002919 A1 CL 2018002919A1
Authority
CL
Chile
Prior art keywords
octenidine
preservative
compositions containing
dose compositions
antimicrobial polyamide
Prior art date
Application number
CL2018002919A
Other languages
English (en)
Inventor
Guillaume Rigaut
Celine Loss-Dunod
Alexis Guy Andre Lucien Parisot
Paredeep K Dahl
Original Assignee
Merial Inc
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc, Genzyme Corp filed Critical Merial Inc
Publication of CL2018002919A1 publication Critical patent/CL2018002919A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Dermatology (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

LA PRESENTE INVENCIÓN SE RELACIONA A CONSERVADORES NO MERCURIALES, QUE INCLUYEN POLÍMEROS DE POLIAMIDA ANTIMICROBIANA Y OCTENIDINA, Y A MÉTODOS DE USO DE LOS MISMOS PARA PRODUCIR FORMULACIONES DE MÚLTIPLES DOSIS QUE CONTIENEN CONSERVADOR. LAS FORMULACIONES DE MÚLTIPLES DOSIS QUE CONTIENEN CONSERVADOR EXHIBEN RESISTENCIA A UNO O MÁS MICROORGANISMOS CONTAMINANTES, Y TIENEN PROPIEDADES VENTAJOSAS CON RESPECTO A LA ESTABILIDAD A LARGO PLAZO DE INGREDIENTES ACTIVOS BIOLÓGICOS Y DE MOLÉCULA PEQUEÑA.
CL2018002919A 2016-04-14 2018-10-12 Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina. CL2018002919A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662322258P 2016-04-14 2016-04-14

Publications (1)

Publication Number Publication Date
CL2018002919A1 true CL2018002919A1 (es) 2019-01-18

Family

ID=59215875

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018002919A CL2018002919A1 (es) 2016-04-14 2018-10-12 Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina.

Country Status (14)

Country Link
US (1) US10583154B2 (es)
EP (1) EP3442587B1 (es)
JP (1) JP7089479B2 (es)
KR (1) KR20180129949A (es)
CN (1) CN109310776B (es)
AU (1) AU2017248674B2 (es)
BR (1) BR112018071125A8 (es)
CA (1) CA3020634A1 (es)
CL (1) CL2018002919A1 (es)
CO (1) CO2018012113A2 (es)
EA (1) EA039370B1 (es)
ES (1) ES2898798T3 (es)
MX (1) MX2018012477A (es)
WO (1) WO2017180916A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200383932A1 (en) * 2019-06-05 2020-12-10 The Florida International University Board Of Trustees Biotherapy for viral infections using biopolymer based micro/nanogels

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK590288D0 (da) 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US5777095A (en) 1988-10-24 1998-07-07 Symbicom Aktiebolag Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90
ATE292980T1 (de) 1996-10-11 2005-04-15 Univ California Immunostimulierende oligonucleotidekonjugate
CA2278684C (en) * 1997-02-06 2007-04-10 Merck & Co., Inc. Thimerosal-free preservatives for vaccines
US6368603B1 (en) 1997-03-05 2002-04-09 Merial Limited Lyme combination compositions and uses
AUPP584298A0 (en) * 1998-09-14 1998-10-08 Starpharma Limited Antimicrobial and antiparasitic agents
RU2195269C2 (ru) * 2001-02-14 2002-12-27 Общество с ограниченной ответственностью "МДТ" Витаминно-минеральный комплекс
DE10205883A1 (de) * 2002-02-13 2003-08-21 Schuelke & Mayr Gmbh Wässriges Antiseptikum auf Basis von Bispyridiniumalkanen
WO2005009462A2 (en) * 2003-07-24 2005-02-03 Merial Limited Vaccine formulations comprising an oil-in-water emulsion
DE102005045145A1 (de) * 2005-09-15 2007-03-29 Schülke & Mayr GmbH Verwendung von Octenidindihydrochlorid in halbfesten Zubereitungen
CN101366945A (zh) * 2008-08-21 2009-02-18 浙江卫信生物药业有限公司 不含甲醛和硫柳汞的吸附白喉疫苗的配制方法
DK2575872T3 (da) * 2010-06-01 2020-10-19 Seqirus Uk Ltd Koncentrering af influenzavaccineantigener uden frysetørring
EP3170508B1 (en) 2010-06-04 2019-11-13 Wyeth LLC Vaccine formulations
EP2970586B1 (en) * 2013-03-15 2022-12-07 Genzyme Corporation Amine functional polyamides

Also Published As

Publication number Publication date
EA201892330A1 (ru) 2019-03-29
US20170296577A1 (en) 2017-10-19
AU2017248674B2 (en) 2021-04-01
MX2018012477A (es) 2019-03-07
CN109310776B (zh) 2022-02-11
CA3020634A1 (en) 2017-10-19
CO2018012113A2 (es) 2019-02-08
EP3442587B1 (en) 2021-08-18
CN109310776A (zh) 2019-02-05
EA039370B1 (ru) 2022-01-19
US10583154B2 (en) 2020-03-10
BR112018071125A2 (pt) 2019-02-05
EP3442587A1 (en) 2019-02-20
KR20180129949A (ko) 2018-12-05
AU2017248674A1 (en) 2018-11-01
ES2898798T3 (es) 2022-03-08
JP7089479B2 (ja) 2022-06-22
BR112018071125A8 (pt) 2022-06-28
WO2017180916A1 (en) 2017-10-19
JP2019513793A (ja) 2019-05-30

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