CO2018008184A2 - Virus de vacuna del síndrome respiratorio y reproductivo porcino - Google Patents

Virus de vacuna del síndrome respiratorio y reproductivo porcino

Info

Publication number
CO2018008184A2
CO2018008184A2 CONC2018/0008184A CO2018008184A CO2018008184A2 CO 2018008184 A2 CO2018008184 A2 CO 2018008184A2 CO 2018008184 A CO2018008184 A CO 2018008184A CO 2018008184 A2 CO2018008184 A2 CO 2018008184A2
Authority
CO
Colombia
Prior art keywords
viruses
live
reproductive syndrome
modified
vaccine virus
Prior art date
Application number
CONC2018/0008184A
Other languages
English (en)
Inventor
Ying Fang
Stephen Wu
Original Assignee
Elanco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elanco Us Inc filed Critical Elanco Us Inc
Publication of CO2018008184A2 publication Critical patent/CO2018008184A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10061—Methods of inactivation or attenuation
    • C12N2770/10064—Methods of inactivation or attenuation by serial passage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a un virus del Síndrome Respiratorio y Reproductivo Porcino vivo, modificado. Los virus fueron genéticamente analizados y seleccionados con base en el agrupamiento filogenético para modificación por transferencia repetida en cultivo de tejidos. Los virus vivos, modificados se evaluaron por la capacidad para proporcionar inmunidad protectora a virus heterólogos. Los virus vivos modificados son útiles en vacunas, particularmente en vacunas las cuales pueden transferir infección de cerdos por virus heterólogos múltiples.
CONC2018/0008184A 2016-02-18 2018-08-01 Virus de vacuna del síndrome respiratorio y reproductivo porcino CO2018008184A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662296658P 2016-02-18 2016-02-18
PCT/US2017/017290 WO2017142798A1 (en) 2016-02-18 2017-02-10 Porcine reproductive and respiratory syndrome vaccine virus

Publications (1)

Publication Number Publication Date
CO2018008184A2 true CO2018008184A2 (es) 2018-08-21

Family

ID=58057334

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2018/0008184A CO2018008184A2 (es) 2016-02-18 2018-08-01 Virus de vacuna del síndrome respiratorio y reproductivo porcino

Country Status (17)

Country Link
US (2) US10155035B2 (es)
EP (1) EP3416682A1 (es)
JP (2) JP6840159B2 (es)
KR (4) KR20200049905A (es)
CN (1) CN108697787B (es)
AU (2) AU2017219594B2 (es)
BR (1) BR112018015912A2 (es)
CA (2) CA3014615A1 (es)
CL (2) CL2018002123A1 (es)
CO (1) CO2018008184A2 (es)
EA (1) EA201891555A1 (es)
MX (2) MX2018009956A (es)
NZ (1) NZ744054A (es)
PH (1) PH12018501750A1 (es)
SG (1) SG11201805611RA (es)
TW (2) TWI704225B (es)
WO (1) WO2017142798A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI704225B (zh) * 2016-02-18 2020-09-11 美商益農美國公司 豬繁殖與呼吸綜合症疫苗病毒
BR112021026502A2 (pt) * 2019-08-29 2022-03-15 Elanco Uk Ah Ltd Vírus de vacina de síndrome reprodutiva e respiratória porcina
CN113151493B (zh) * 2021-04-01 2023-09-15 吉林省养蜂科学研究所（吉林省蜂产品质量管理监督站、吉林省蜜蜂遗传资源基因保护中心） 一种长白山东方蜜蜂ssr标记引物组、pcr鉴定方法以及应用
CN114292961A (zh) * 2022-01-29 2022-04-08 龙岩学院 鉴定类nadc-30毒株的实时荧光rt-pcr检测引物和探针组

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2251419T3 (da) 1999-04-22 2012-07-02 Us Agriculture Porcint reproduktions- og respirations-syndrom-vaccine baseret på isolat JA-142
CN103695465A (zh) * 2013-12-16 2014-04-02 中国农业科学院哈尔滨兽医研究所 猪繁殖与呼吸综合征病毒疫苗株cDNA感染性克隆及其应用
JP6538071B2 (ja) * 2014-03-21 2019-07-03 ニューテック・ベンチャーズ 非天然発生のブタ生殖器呼吸器症候群ウイルス（ｐｒｒｓｖ）及び使用する方法
TWI704225B (zh) * 2016-02-18 2020-09-11 美商益農美國公司 豬繁殖與呼吸綜合症疫苗病毒

Also Published As

Publication number Publication date
KR102553823B1 (ko) 2023-07-07
TWI704225B (zh) 2020-09-11
NZ744054A (en) 2020-03-27
BR112018015912A2 (pt) 2019-01-22
US10155035B2 (en) 2018-12-18
EP3416682A1 (en) 2018-12-26
JP2019505217A (ja) 2019-02-28
CA3081982A1 (en) 2017-08-24
JP7053552B2 (ja) 2022-04-12
KR20200049905A (ko) 2020-05-08
AU2019203817A1 (en) 2019-06-20
KR20220027292A (ko) 2022-03-07
TWI652347B (zh) 2019-03-01
CL2021003211A1 (es) 2022-08-05
TW201907006A (zh) 2019-02-16
KR102553821B1 (ko) 2023-07-07
CN108697787A (zh) 2018-10-23
CN108697787B (zh) 2023-01-10
MX2022008809A (es) 2022-08-11
MX2018009956A (es) 2018-11-29
AU2017219594B2 (en) 2019-06-27
CL2018002123A1 (es) 2018-11-23
US10300126B2 (en) 2019-05-28
KR20180100231A (ko) 2018-09-07
PH12018501750A1 (en) 2019-05-15
AU2017219594A1 (en) 2018-07-19
CA3014615A1 (en) 2017-08-24
US20170239343A1 (en) 2017-08-24
JP2020036593A (ja) 2020-03-12
US20190022208A1 (en) 2019-01-24
JP6840159B2 (ja) 2021-03-10
TW201738374A (zh) 2017-11-01
WO2017142798A1 (en) 2017-08-24
KR20200072565A (ko) 2020-06-22
SG11201805611RA (en) 2018-07-30
AU2019203817B2 (en) 2020-05-21
EA201891555A1 (ru) 2019-01-31

Similar Documents

Publication Publication Date Title
CO2018008184A2 (es) Virus de vacuna del síndrome respiratorio y reproductivo porcino
PH12018501602A1 (en) Subunit immersion vaccines for fish
CY1124254T1 (el) Μεθοδοι και συνθεσεις για την προκληση προστατευτικης ανοσιας εναντι λοιμωξης ιου της ανθρωπινης ανοσοανεπαρκειας
BR112018008090A2 (pt) vacina de vírus do herpes simplex.
TW201613558A (en) Novel vaccine compositions for porcine epidemic diarrhea virus and porcine deltacoronavirus
MX2016012845A (es) Vacuna contra el virus de la diarrea epidemica porcina.
BR112018012642A2 (pt) vacina de calicivírus felino
CY1120430T1 (el) Ανασυνδυασμενες cdv συνθεσεις και χρησεις αυτων
PH12017501370A1 (en) Bivalent swine influenza virus vaccine
CO7461133A2 (es) Parvovirus 5a porcino, métodos de uso y vacuna
CO7461135A2 (es) Parvovirus porcino 5b, métodos de uso y vacuna
CO2017001614A2 (es) Vacuna en vector recombinante de adenovirus aviar serotipo 9
EA201991041A1 (ru) Вакцина против свиного парвовируса и вируса свиного репродуктивного и респираторного синдрома и способы ее получения
CL2023002187A1 (es) Virus para vacuna contra el síndrome respiratorio y reproductivo porcino
UY35418A (es) Vacuna que proporciona protección frente a diferentes Picornavirus humanos.
BR112018002107A2 (pt) resposta imune potencializada em espécies suínas
CL2019000405A1 (es) Vacunas virales.
AR109291A1 (es) Clon de adnc del virus del síndrome reproductivo y respiratorio porcino y usos del mismo
BR112017004703A2 (pt) ?vacina e método para proteção de progênie de uma porca contra infeccção por um vírus de diarreia endêmica suína?
EA201992167A1 (ru) Вакцина
UA119801U (uk) Вірус-вакцина-2 проти інфекційної бурсальної хвороби птиці (хвороби гамборо) зі штаму "ум-93"
UA125934U (uk) АвіВАК-ІЕКВМ-ВАКЦИНА АСОЦІЙОВАНА ІНАКТИВОВАНА ПРОТИ НЬЮКАСЛСЬКОЇ ХВОРОБИ, ІНФЕКЦІЙНОГО БРОНХІТУ КУРЕЙ ТА СИНДРОМУ ЗНИЖЕННЯ НЕСУЧОСТІ
TH176276A (th) พอซีนพาโวไวรัส 5b, วิธีการใช้และวัคซีน
CR20110469A (es) Vacuna inactivada del virus del dengue con un adjuvante libre de aluminio