CN2870885Y - Long-effective depressor submerged rod - Google Patents
Long-effective depressor submerged rod Download PDFInfo
- Publication number
- CN2870885Y CN2870885Y CN 200520122496 CN200520122496U CN2870885Y CN 2870885 Y CN2870885 Y CN 2870885Y CN 200520122496 CN200520122496 CN 200520122496 CN 200520122496 U CN200520122496 U CN 200520122496U CN 2870885 Y CN2870885 Y CN 2870885Y
- Authority
- CN
- China
- Prior art keywords
- utility
- medicine
- model
- blood pressure
- long
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Media Introduction/Drainage Providing Device (AREA)
- Medicinal Preparation (AREA)
Abstract
The utility model relates to a long-effective depressor submerged rod, which is made by enclosing a hypotensor into a medical silicone rubber tube and sealing the two ends of the tube by a medical adhesive. The outer diameter of the submerged rod is 2-2.4mm, and its inner diameter is 1.8-2.2mm. The bonding points at two ends of the tube are 1.5mm, and the length of enclosed medicine in the tube is 20-40mm. The utility model is implanted to the subcutaneous layer of upper limb biceps brachii of the patients with hypertension to control the slow releasing of medicine, thereby achieves long-acting hypotensive effect and stabilization of blood pressure. The utility model eliminates pains of patients with hypertension of lifelong medicine-taking, avoids stimulation of medicine to stomach and prevents sudden cardiovascular and cerebrovascular diseases effectively. As the utility model can stabilize the blood pressure for a long period, it can reduce cardiovascular and cerebrovascular cirrhosis effectively and prevent injury of target organs efficiently.
Description
This utility model provides a kind of long acting blood pressure reducing heeling-in rod for the treatment of hypertension.It is that a kind of silicone rubber tube that utilizes is packed Altace Ramipril into and the heeling-in rod made, and it is subcutaneous that the method for clinical employing subdermal implantation is imbedded, and just can make the blood pressure long-term stability in normal range.
At present, treat both at home and abroad hypertension and stabilizing blood pressure mainly by every day enalapril meleate keep the blood pressure normal condition.Hypotensor is of a great variety, once takes to reach steady in a long-term normal.If, perhaps ignored hypertensive harm and withdrawn depressor, or just may cause that blood pressure raises suddenly when excited and tired, bring out sudden cardiovascular and cerebrovascular disease, be taken by surprise, cause death and deformity in case forget and take depressor.Secular hypertension and instability cause target organ damage easily.The implant that a kind of omega-fatty acid is arranged, this type of medicine neither depressor, belong to hypolipidemic, can not reach the purpose of stabilizing blood pressure blood pressure lowering clinically, and be more can not stabilizing blood pressure after once using normal.
The purpose of this utility model is exactly to provide a kind of long acting blood pressure reducing heeling-in rod in order to overcome the weak point in the existing technology, and implant into body upper limb biceps brachii m. is subcutaneous, thereby slowly carries out the purpose that control drug release reaches the steady blood pressure of long acting blood pressure reducing.
The technical scheme that its technical problem that solves this utility model adopts is: adopt medical silicone rubber tube, and the depressor of packing in the pipe, the pipe two ends are sealed with adhesive of medical, have both made the long-acting blood that falls. press the heeling-in rod.This silicone rubber tube has a lot of micropores, and its external diameter is 2mm-2.4mm, and internal diameter is 1.8mm-2.2mm, and the adhesive spots length at pipe two ends is respectively 1.5mm.The effective length of powder charge is 20mm-40mm.
Action principle: long acting blood pressure reducing heeling-in rod imbed subcutaneous after, because of its tube wall silicone rubber tube has a lot of micropores, again because the inside and outside drug concentrations of silicone rubber tube is poor, make medicine by diffusing into organismic internal environment merely, by blood circulation performance pharmacological action, reach the purpose of blood pressure lowering, its silicone rubber tube wall thickness and length are used for controlling medicine in the burst size of subcutaneous unit interval, and the medication dosing of packing into is that to determine to continue in vivo to discharge be the time.Subcutaneous every day every sustained release depressor 50 micrograms, the dose in every heeling-in rod is sustained release 3-5 in vivo, and stable normal range.Can take out after drug release is intact, imbed new long acting blood pressure reducing heeling-in rod more again.Thereby solved the misery that the hypertensive patient takes medicine all the life.Because of subdermal implantation absorbs without enteral digestion, so avoided the destruction of various digestive enzyme and gastric acid and the influence of food, so bioavailability is greatly improved, curative effect is than oral drug effect height.The medicine of trace can produce very high curative effect.Prevented the generation of sudden cardiovascular and cerebrovascular disease in the 3--5 effectively.Because can keep blood pressure steady in a long-term normal, thereby effectively prevented the damage of target organ.
Good effect of the present utility model: solved the misery that the hyperpietic takes medicine all the life, avoided taking medicine stimulation effectively, effectively prevented the generation of sudden cardiovascular and cerebrovascular disease, because of long-term blood pressure stabilization has reduced cerebrovascular sclerosis effectively to stomach.
The utility model is described in further detail below in conjunction with drawings and Examples.
Figure (1) is a cut-away structure chart of the present utility model.
Sequence number and title among the figure: (1) silicone rubber tube (2) hypotensor (3) adhesive spots
The hypotensor (2) of packing in the silicone rubber tube (1) in the drawings forms an adhesive spots (3) with adhesive of medical sealing two ends then and had both made long acting blood pressure reducing heeling-in rod.Use plastic bag packaging then, use ethylene oxide sterilizing.According to the height of different blood pressures, select 4-6 to prop up long acting blood pressure reducing heeling-in rod, during use at biceps brachii m. place skin routine disinfection, scope 20cm
2-40cm
2, do local anesthesia with 0.35% bupivacaine, it is subcutaneous to thrust the disinfectant biceps brachii m. with No. 26 puncture needles then, long acting blood pressure reducing heeling-in rod 4-6 is propped up be fan-shaped and imbed subcutaneously, and long acting blood pressure reducing heeling-in rod afterbody is exposed outside the skin.Can card sealing puncture get final product with wound then.
Claims (1)
1, a kind of long acting blood pressure reducing heeling-in rod of forming by silicone rubber tube and hypotensor, it is characterized in that it is the 20--40 millimeter that this utility model is selected length for use, external diameter is the 2--2.4 millimeter, internal diameter is the medical grade silicon rubber pipe of 1.8--2.2 millimeter, the hypotensor of packing in the pipe, two ends are sealed with medical adhesive.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200520122496 CN2870885Y (en) | 2005-09-20 | 2005-09-20 | Long-effective depressor submerged rod |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200520122496 CN2870885Y (en) | 2005-09-20 | 2005-09-20 | Long-effective depressor submerged rod |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2870885Y true CN2870885Y (en) | 2007-02-21 |
Family
ID=37739235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200520122496 Expired - Fee Related CN2870885Y (en) | 2005-09-20 | 2005-09-20 | Long-effective depressor submerged rod |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2870885Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147606A (en) * | 2014-08-15 | 2014-11-19 | 吕鹏威 | Biodegradable subcutaneous implant rod used for long-acting pressure reduction |
| CN107753418A (en) * | 2017-11-20 | 2018-03-06 | 中国农业科学院北京畜牧兽医研究所 | Medicament slow release implants and heeling-in device |
-
2005
- 2005-09-20 CN CN 200520122496 patent/CN2870885Y/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147606A (en) * | 2014-08-15 | 2014-11-19 | 吕鹏威 | Biodegradable subcutaneous implant rod used for long-acting pressure reduction |
| CN104147606B (en) * | 2014-08-15 | 2016-03-16 | 吕鹏威 | For the biodegradation subdermal implantation rod of long-acting blood pressure lowering |
| CN107753418A (en) * | 2017-11-20 | 2018-03-06 | 中国农业科学院北京畜牧兽医研究所 | Medicament slow release implants and heeling-in device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0153825B1 (en) | Device for sustained release of active substance | |
| AU685420B2 (en) | Smooth muscle chemical pacemaker | |
| CN101028211B (en) | Artificial implant general medicine feeder | |
| CN105288831B (en) | A kind of biodegradation type drug delivery system of hollow tubular and preparation method thereof | |
| CN2870885Y (en) | Long-effective depressor submerged rod | |
| CN113262200A (en) | Intelligent sustained-release injection for treating male sexual dysfunction and preparation method thereof | |
| US20130197468A1 (en) | Device for Intramyocardial Delivery | |
| CN108743955A (en) | One kind being used for essential hypertension elastomer subdermal implantation stick | |
| CN107375191A (en) | One kind is used for long-acting hypoglycemic elastomer subdermal implantation rod | |
| CN104147606B (en) | For the biodegradation subdermal implantation rod of long-acting blood pressure lowering | |
| CN102718693B (en) | Carbazochrome sodium sulfonate compound and composition thereof | |
| CN201147507Y (en) | Long-acting blood pressure-reducing sustained-release degradation stick | |
| CN102974025B (en) | A kind of one-off cervix dilator with medicine film | |
| CN210185713U (en) | Skin expander for burn plastic surgery | |
| CN202185055U (en) | Long-acting subcutaneous injection bar with hypotensive medicine | |
| CN214633242U (en) | Fully-implanted deep continuous administration silicone capsule tube system | |
| CN209695528U (en) | Alleviating pain and detumescence sheath patch | |
| CN113440473A (en) | Subcutaneous implanted rod for long-acting blood sugar reduction and preparation method thereof | |
| CN107198574A (en) | A kind of skin dilator and the method for expanding skin | |
| CN202409548U (en) | Subcutaneous implantable antipsychotics slow-release bar device | |
| CN201643422U (en) | Implanted neural electrical stimulation system with drug releasing device | |
| CN105919925B (en) | Macromolecule hydrogel, preparation method and its application | |
| CN202198976U (en) | Multifunctional intracranial tumor mesenchyme radiotherapy and chemotherapy pump | |
| CN1028486C (en) | Absorbable slow-solution medicinal membrane and preparation thereof | |
| CN1410063A (en) | Embedding agent for long acting blood pressure reducing |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20070221 Termination date: 20120920 |