CN2483709Y - Quick-positional feeding apparatus for trace amount of sample - Google Patents

Quick-positional feeding apparatus for trace amount of sample Download PDF

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Publication number
CN2483709Y
CN2483709Y CN 01206781 CN01206781U CN2483709Y CN 2483709 Y CN2483709 Y CN 2483709Y CN 01206781 CN01206781 CN 01206781 CN 01206781 U CN01206781 U CN 01206781U CN 2483709 Y CN2483709 Y CN 2483709Y
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CN
China
Prior art keywords
sample
detection cell
peristaltic pump
sensor
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN 01206781
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Chinese (zh)
Inventor
田学隆
罗庆慧
莫志宏
郭刚
吴中福
靳萍
刘国传
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Chongqing University
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Chongqing University
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Filing date
Publication date
Application filed by Chongqing University filed Critical Chongqing University
Priority to CN 01206781 priority Critical patent/CN2483709Y/en
Application granted granted Critical
Publication of CN2483709Y publication Critical patent/CN2483709Y/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

A sample injection device using for detector of the utility model relates to detector used in fields of biology, medicine, environmental sanitation monitoring, food quality test, etc, aiming at solving the problem of low speed for injection and inaccurate positioning of prior art. The device comprises a shell (14), an automatic control circuit board (1), suction needles (11) orderly connected, a peristaltic pump (5), a detection cell (15), a waste liquid bottle (9). A piezoelectric biochip sensor (7) is provided in the detection cell. The front of the peristaltic pump passes through a three-position three-way liquid flow direction conversion valve (4) and is respectively connected with the suction needle, an air filter (2), a cleaning fluid bottle (3). The inlet and outlet of the detection cell are respectively provided with an inlet liquid position sensor (6) and an outlet liquid position sensor (8). The device is suitable to inject samples of piezoelectric biochip detection in fields of biology, medicine, environmental sanitation monitoring, food quality test, etc; as well as can be used for automatic injection of automatic biochemical analyzer of other liquid detection.

Description

Micro sample is located sampling device fast
Technical field
The utility model relates to the micro liquid sample sampling device of the piezoelectric type biochip supplies analysis in fields such as being used for biology, medical science, environmental health monitoring and surveilliance, food quality inspection.
Background technology
Existing liquor sample sampling device generally all adopts the sample introduction of constant speed, reaches the automatic control circuit board of wherein controlling the sample introduction process, formations such as the suction spindle of Lian Tonging, peristaltic pump, detection cell, waste liquid bottle successively by housing usually.This sampling device needs more sample size usually; Sample introduction excessive velocities when adopting micro-sampling, and sample is difficult for accurately reaching the detection cell position.
The utility model content
Given this, the purpose of this utility model is to provide that a kind of required sample that can be used for the piezoelectric type biochip supplies analysis is few, sample sample introduction speed fast, the micro sample of accurate positioning is located sampling device fast.
The utility model adopts and 3-position-3-way flow direction cross-over valve is being set to reduce with realizing its purpose the switching time between air and cleaning fluid cleaning detection pipeline and the sample introduction between suction spindle, air strainer, cleaning fluid bottle three and the peristaltic pump, and further divide at the entrance and exit of detection cell and import liquid position sensor is set in addition and outlet liquid position sensor is realized its purpose, the thermostat that further is provided with semiconductor heating and cooling sheet and temperature sensor again in detection cell is realized its purpose.
Micro sample of the present utility model is located sampling device fast, comprise housing (14) and reach the automatic control circuit board (1) of wherein controlling the sample introduction process, the suction spindle (11), peristaltic pump (5), detection cell (15), the waste liquid bottle (9) that are communicated with are successively arranged, piezoelectric type biochip sensor (7) is arranged in the detection cell, and peristaltic pump the place ahead is communicated with suction spindle, air strainer (2), cleaning fluid bottle (3) respectively through 3-position-3-way flow direction cross-over valve (4).
The entrance and exit of above-mentioned detection cell (15) has import liquid position sensor (6) and outlet liquid position sensor (8) respectively.
Above-mentioned 2, require 1 described micro-test sample to locate sampling device fast according to letter of authorization, it is characterized in that thermostat (10) is arranged in the said detection cell (15), said piezoelectric type biochip sensor (7) places thermostat, thermostat that semiconductor heating and cooling sheet (12) and temperature sensor (13) are arranged.
During the utility model work, under the control of the circuit of automatic control circuit board 1, the direction of flow cross-over valve is respectively successively with the cleaning fluid bottle, air strainer, suction spindle is connected through peristaltic pump and detection pipeline, after pipeline cleans sample is being sucked the detection pipeline fast to detecting under the effect of peristaltic pump, and in of the effect of import liquid position sensor with outlet liquid position sensor, the control fluid sample enters the amount and the residence time of detection cell, thereby realize the quick location sample introduction of sample, thermostat guarantees to detect and carries out under steady temperature, and the sample after the detection enters waste liquid bottle.
The utility model and existing sampling device relatively, this sampling device can realize detecting the automatic cleaning of pipeline, automatically drain the interior cleaning fluid of detection pipeline, the liquor sample of trace sent into fast in the detection cell of piezoelectric type biochip sensor and and carries out thermostatic control the detection cell temperature.Whole testing process is carried out in a closed pipeline, is difficult for making sample contaminated.Under the micro sample situation, if adopt existing constant speed sampling device, the sample introduction excessive velocities of sample, sample is difficult for accurately reaching the detection cell position; If sample introduction speed is slow excessively, then sample introduction need expend the plenty of time.The utility model is respectively arranged with import liquid position sensor and outlet liquid position sensor in the porch and the exit of detection cell, can be according to sample at ducted situation, the rotating speed of control peristaltic pump is realized sample positioning control fast and accurately in real time, and required sample size is less than 0.2ml.Therefore the utlity model has that required sample is few, sample sample introduction speed fast, the advantage of accurate positioning.
The utility model is used for the sample sample introduction of the piezoelectric type biochip supplies analysis in fields such as biology, medical science, environmental health monitoring and surveilliance, food quality inspection; The auto injection that also can be used for the automatic biochemistry analyzer of other Liquid Detection.
Below, the utility model is further described to use embodiment and accompanying drawing thereof again.
Description of drawings
Fig. 1 is the structural representation of a kind of detector of the present utility model with the sample sampling device.
Fig. 2 is the work connection diagram of each assembly of Fig. 1.
Fig. 3 is the structural representation of the thermostat of Fig. 1.
Embodiment
A kind of detector sample sampling device of the present utility model, as shown in drawings.
What this sampling device had a common structure is installed in the stepped housing of each assembly 14.The automatic control circuit board 1 of control sample introduction overall process is installed in the front step of housing.The specimen preparation device that is installed in the sample test tube is arranged on step surface.The air cleaner that communicates with atmosphere 2, the cleaning fluid bottle 3 of splendid attire cleaning fluid, the flow direction cross-over valve 4 of 3-position-3-way structure, the waste liquid bottle 9 of common structure are installed in the side of housing.Peristaltic pump 5, the detection cell 15 of common structure are installed in the stage at housing rear portion.With common pipeline that suction spindle 11, aircleaner 2, the lotion bottle 3 of common structure is logical with three imports of peristaltic pump 5 respectively.The delivery side of pump of will wriggling is communicated with detection cell 15, is communicated with the detection pipeline that constitutes sealing again with waste liquid bottle 9.The import liquid position sensor 6 and the outlet liquid position sensor 8 of photo-electric are installed respectively at the entrance and exit of detection cell.The thermostat 10 of common structure as shown in Figure 3 is installed in detection cell, thermostat is made of framework and the temperature sensor 13 that is installed in the semiconductor heating and cooling sheet 12 of the common structure on the framework and is installed in appropriate location in the framework, and the piezoelectric type biochip sensor 7 of logical structure is installed in the thermostat.Aforesaid liquid flows to the circuit communication on cross-over valve 4, peristaltic pump 5, import liquid position sensor 6, thermostat 10, outlet liquid position sensor 8 and the automatic control circuit board 1.Constitute this sampling device.
In the utility model when work,, under the control of the circuit of automatic control circuit board 1, direction of flow cross-over valve 4 is communicated with cleaning fluid bottles 3 and detects pipelines, and under the effect of peristaltic pump 5, the cleaning fluid in the cleaning fluid bottle cleans detecting pipeline automatically; After cleaning end, the tangential automatically air strainers 2 that are communicated with of flow direction cross-over valve 4, peristaltic pump 5 makes the air after the filtration that cleaning fluid is discharged from detect pipeline; Suction spindle 11 in the liquor sample of the test tube of the tangential automatically connection insertion of flow direction cross-over valve 4 subsequently, peristaltic pump 5 sucks the detection pipeline fast with sample, after the import liquid position sensor 6 of detection cell 15 imports detects sample, thereby the rotating speed that reduces peristaltic pump 5 immediately pushes sample at a slow speed in the detection cell 15, when the outlet liquid position sensor 8 of detection cell outlet detects sample, stop peristaltic pump work immediately, sample is accurately rested in the detection cell 15 of piezoelectric type biochip sensor 7, thereby realize the quick location sample introduction of sample, thermostat carries out under steady temperature to guarantee to detect, and the sample fluid after enters waste liquid bottle 9 after testing.

Claims (3)

1, micro sample is located sampling device fast, comprise housing (14) and reach the automatic control circuit board (1) of wherein controlling the sample introduction process, the suction spindle (11), peristaltic pump (5), detection cell (15), the waste liquid bottle (9) that are communicated with are successively arranged, it is characterized in that having in the detection cell piezoelectric type biochip sensor (7), peristaltic pump the place ahead is communicated with suction spindle, air strainer (2), cleaning fluid bottle (3) respectively through 3-position-3-way flow direction cross-over valve (4).
2, require 1 described micro-test sample to locate sampling device fast according to letter of authorization, it is characterized in that the entrance and exit of said detection cell (15) has import liquid position sensor (6) and outlet liquid position sensor (8) respectively.
3, require 1 or 2 described micro-test samples to locate sampling device fast according to letter of authorization, it is characterized in that thermostat (10) is arranged in the said detection cell (15), said piezoelectric type biochip sensor (7) places thermostat, thermostat that semiconductor heating and cooling sheet (12) and temperature sensor (13) are arranged.
CN 01206781 2001-07-10 2001-07-10 Quick-positional feeding apparatus for trace amount of sample Expired - Fee Related CN2483709Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 01206781 CN2483709Y (en) 2001-07-10 2001-07-10 Quick-positional feeding apparatus for trace amount of sample

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 01206781 CN2483709Y (en) 2001-07-10 2001-07-10 Quick-positional feeding apparatus for trace amount of sample

Publications (1)

Publication Number Publication Date
CN2483709Y true CN2483709Y (en) 2002-03-27

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Application Number Title Priority Date Filing Date
CN 01206781 Expired - Fee Related CN2483709Y (en) 2001-07-10 2001-07-10 Quick-positional feeding apparatus for trace amount of sample

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CN (1) CN2483709Y (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102549421A (en) * 2009-09-07 2012-07-04 株式会社岛津制作所 Autosampler
CN102890063A (en) * 2012-10-10 2013-01-23 长春理工大学 Multi-parameter portable automatic food safety detector
CN103163308A (en) * 2011-12-12 2013-06-19 恩德莱斯和豪瑟尔测量及调节技术分析仪表两合公司 Sample preparation system for an analytical system for determining a measured variable of a liquid sample
CN104492742A (en) * 2015-01-06 2015-04-08 北京九州泰康生物科技有限责任公司 Biochip cleaning device

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102549421A (en) * 2009-09-07 2012-07-04 株式会社岛津制作所 Autosampler
CN102549421B (en) * 2009-09-07 2015-02-11 株式会社岛津制作所 Autosampler
CN103163308A (en) * 2011-12-12 2013-06-19 恩德莱斯和豪瑟尔测量及调节技术分析仪表两合公司 Sample preparation system for an analytical system for determining a measured variable of a liquid sample
CN103163308B (en) * 2011-12-12 2014-08-13 恩德莱斯和豪瑟尔测量及调节技术分析仪表两合公司 Sample preparation system for an analytical system for determining a measured variable of a liquid sample
CN102890063A (en) * 2012-10-10 2013-01-23 长春理工大学 Multi-parameter portable automatic food safety detector
CN104492742A (en) * 2015-01-06 2015-04-08 北京九州泰康生物科技有限责任公司 Biochip cleaning device

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C19 Lapse of patent right due to non-payment of the annual fee
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