CN220823876U

CN220823876U - Novel cell cryopreservation bag

Info

Publication number: CN220823876U
Application number: CN202322471564.0U
Authority: CN
Inventors: 曹玉杰; 王树敏; 李雪岩; 沈锋; 祝可欣; 李莹
Original assignee: Beijing Guoyi Biotechnology Co ltd
Current assignee: Beijing Guoyi Biotechnology Co ltd
Priority date: 2023-09-12
Filing date: 2023-09-12
Publication date: 2024-04-23
Anticipated expiration: 2033-09-12

Abstract

The utility model belongs to the technical field of medical instruments, and discloses a novel cell freezing bag which comprises a freezing bag body, wherein a label is fixedly arranged at the upper end of one side of the freezing bag body, a groove is formed in the bottom end of the freezing bag body, an infusion tube and a liquid outlet tube are fixedly arranged at the top of the freezing bag body, and a first rotary cap is movably connected to one end, far away from the freezing bag body, of the liquid outlet tube. According to the utility model, through the cooperation of the structures such as the extension pipe, the dispersion pipe and the like, the effect that the cells in the freezing bag can be frozen into a very thin small borneol, the recovery time is shortened during recovery, the cell survival rate is improved, the cell survival rate is moved to the bottommost part of the extension pipe, flows into the dispersion pipe, is uniformly distributed into the inner cavity of the freezing bag body through the holes of the dispersion pipe, and when the cells are taken out, the first screw cap is pulled out, and the standard pipeline is connected to the top of the liquid outlet pipe, so that the effect of getting rid of the strict requirements of the freezing operation on the field is achieved.

Description

Novel cell cryopreservation bag

Technical Field

The utility model belongs to the technical field of medical instruments, and particularly relates to a novel cell cryopreservation bag.

Background

The freezing bag is an independently aseptically packaged medical bag body made of medical EVA low-temperature resistant materials, and is mainly used for long-time storage and transportation of biological products such as blood, cells, vaccines, viruses and the like at low temperature, such as storage of stem cells, storage of umbilical cord blood and the like;

When the cryopreserved cells are recovered, the cells are required to be recovered in a short time, so that death of the cells in the recovery process is reduced, the survival rate of the recovered cells is improved, the cryopreserved tubes are most commonly used in the market at present, the cryopreservation operation is more, the recovery time is slightly long, the cells close to the tube wall are recovered preferentially when the cells are recovered by using the cryopreserved tubes, the cell recovery in the middle of the tubes is slower, the survival rate of the cell recovery is affected, the transferred cell sap has more strict site requirements, and the operation is required to be completed in a biosafety cabinet, so that the improvement is required.

Disclosure of utility model

In order to solve the problems that the cryopreservation operation is more and the recovery time is slightly long, cells close to the tube wall are recovered preferentially when the cells are recovered, and the cell recovery in the middle of the tube is slower, so that the survival rate of the cell recovery is affected, the transferred cell sap has strict site requirements, and the operation must be completed in a biosafety cabinet, the utility model provides a novel cell cryopreservation bag.

In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a novel cell freezes deposits bag, includes freezes deposits bag body, the upper end fixed mounting of freezes deposits bag body one side has the label to paste, the bottom of freezes deposits bag body is seted up flutedly, the top fixed mounting of freezes deposits bag body has infusion pipe and drain pipe, the drain pipe is kept away from the one end swing joint of freezes deposits bag body and is had first cap soon, the one end swing joint that freezes deposits bag body is kept away from to the infusion pipe has the third cap soon, the middle part fixed mounting of infusion pipe has the connecting pipe, the one end swing joint that the infusion pipe was kept away from to the connecting pipe has the second cap soon, the top fixed mounting who freezes deposits bag body inner chamber has the fixed pipe, the bottom fixed mounting of fixed pipe has the extension pipe, the both sides fixed mounting of extension pipe has the dispersion pipe.

Preferably, the dispersing tube is provided with a plurality of holes, and the sizes of the holes are the same.

Preferably, the extension pipe is communicated with the dispersing pipe, and the extension pipe and the dispersing pipe are provided with a gap with the inner cavity wall of the freezing storage bag body.

Preferably, the second screw cap and the first screw cap are in an E shape.

Preferably, the top of the label is provided with a slot, and the material of the label is transparent.

Preferably, the material of the freezing bag body is made of high polymer material EVA.

Preferably, the first screw cap, the second screw cap and the third screw cap are made of rubber materials.

Compared with the prior art, the utility model has the following beneficial effects:

According to the utility model, through the cooperation of structures such as the extension tube, the dispersion tube and the like, cells in the freezing bag can be frozen into a very thin small borneol, the recovery time is shortened during recovery, the effect of improving the survival rate of the cells is achieved, the third screw cap is taken down, the infusion tube is connected with the syringe or the pipette, the cells are injected into the infusion tube, the inner cavity of the fixed tube is drawn into the inner cavity of the fixed tube from the inner wall of the infusion tube, the cells enter the extension tube through the inner cavity of the fixed tube and move to the bottommost part of the extension tube, flow into the dispersion tube, are uniformly distributed into the inner cavity of the freezing bag body through the holes of the dispersion tube, the first screw cap is pulled out when the cells are taken out, and the standard pipeline is connected to the top of the liquid outlet tube, so that the effect of getting rid of strict requirements of the freezing operation on places is achieved.

Drawings

FIG. 1 is a schematic diagram of the structure of the present utility model;

FIG. 2 is a schematic cross-sectional view of the present utility model;

FIG. 3 is a schematic diagram of the structural cooperation of the extension pipe and the dispersion pipe according to the present utility model;

Fig. 4 is a schematic diagram of the overall split structure of the present utility model.

In the figure: 1. a freezing bag body; 2. labeling; 3. a groove; 4. an infusion tube; 5. a liquid outlet pipe; 6. a first screw cap; 7. a connecting pipe; 8. a second screw cap; 9. a fixed tube; 10. an extension tube; 11. a dispersion tube; 12. and a third screw cap.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

As shown in fig. 1 to 4, the utility model provides a novel cell cryopreservation bag, which comprises a cryopreservation bag body 1, wherein a label 2 is fixedly arranged at the upper end of one side of the cryopreservation bag body 1, a groove 3 is formed in the bottom end of the cryopreservation bag body 1, an infusion tube 4 and a liquid outlet tube 5 are fixedly arranged at the top of the cryopreservation bag body 1, a first rotary cap 6 is movably connected to one end, far away from the cryopreservation bag body 1, of the liquid outlet tube 5, a third rotary cap 12 is movably connected to one end, far away from the cryopreservation bag body 1, of the infusion tube 4, a connecting tube 7 is fixedly arranged in the middle of the infusion tube 4, a second rotary cap 8 is movably connected to one end, far away from the infusion tube 4, of the connecting tube 7, a fixing tube 9 is fixedly arranged at the top of an inner cavity of the cryopreservation bag body 1, an extension tube 10 is fixedly arranged at the bottom of the fixing tube 9, and dispersing tubes 11 are fixedly arranged at two sides of the extension tube 10.

As shown in fig. 2 and 3, the dispersing tube 11 is provided with a plurality of holes, the sizes of the holes are the same, the extending tube 10 and the dispersing tube 11 are communicated, the extending tube 10 and the dispersing tube 11 have gaps along with the inner cavity wall of the freezing storage bag body 1, and the second screw cap 8 and the first screw cap 6 are in an E shape.

The scheme is adopted: through the cooperation of fixed pipe 9 and extension pipe 10, take down third cap 12, infusion pipe 4 and syringe or pipette are connected, inject the cell into infusion pipe 4 in, draw into the inner chamber of fixed pipe 9 from the inner wall of infusion pipe 4, get into extension pipe 10 through the inner chamber of fixed pipe 9, move to the bottommost of extension pipe 10, pile up slowly to certain height after, flow into dispersion pipe 11, evenly distribute into the inner chamber of freezing bag body 1 through the hole of dispersion pipe 11 for freezing after the completion, the cell in the freezing bag can freeze into a very thin Borneolum Syntheticum, shortened the recovery time during the recovery, improve cell survival rate, when taking out the cell, pull out first cap 6, connect standard pipeline at the top of drain pipe 5, and the junction is leakless, the strict demand of freezing operation on place has been got rid of.

The scheme is adopted: through the design of dispersion tube 11, the hole that dispersion tube 11 offered makes the cell flow out from the hole, thereby make the even dispersion of cell in the inner chamber of cryopreservation bag body 1, make the cell can freeze into a very thin little borneol, the survival rate when making the cell resuscitate becomes high, through the cooperation of extension tube 10 and dispersion tube 11, extension tube 10 and dispersion tube 11 are linked together, make the cell in the fixed pipe 9 flow into extension tube 10, afterwards flow into dispersion tube 11 from extension tube 10, afterwards flow into the inner chamber of cryopreservation bag body 1 from the hole of dispersion tube 11, thereby make the cell disperse evenly in the inner chamber of cryopreservation bag body 1, through the design of second cap 8 and first cap 6, the restriction of second cap 8 and first cap 6 shape, make the leakproofness of cryopreservation bag better when freezing.

As shown in fig. 1 and 4, the top of the label 2 is provided with a slot, the label 2 is made of transparent material, the freezing bag body 1 is made of high polymer material EVA, and the first rotary cap 6, the second rotary cap 8 and the third rotary cap 12 are made of rubber material.

The scheme is adopted: through the design of label subsides 2, the seting up of label subsides 2 top slotted holes, make the label of the frozen storage bag that will write put into to the slotted hole, make classification and the frozen storage time of more clear cell, transparent material makes can see the content of label clearly, make the label content more clear, through the definition of frozen storage bag body 1 material, the definition of macromolecular material EVA improves the cell activity, the effectual breakage rate that reduces the bag body and freeze in the recovery, be fit for long-term storage in the ultralow temperature environment, and the pliability is extremely strong, shaping seal is good, through the design of first cap 6 and second cap 8 soon, first cap 6 soon, second cap 8 soon and third cap 12 material soon, the setting of rubber material makes infusion tube 4, drain pipe 5 and connecting pipe 7 are under the frozen storage, still can be quick carry out other pipettes and connect simultaneously.

The working principle and the using flow of the utility model are as follows:

When the freezing and preserving device is used, the third screw cap 12 is taken down, the infusion tube 4 is connected with the injector or the pipette, cells are injected into the infusion tube 4, the inner cavity of the fixed tube 9 is drawn into the inner cavity of the infusion tube 4, the cells enter the extension tube 10 through the inner cavity of the fixed tube 9, the cells move to the bottommost part of the extension tube 10, the cells are slowly piled up to a certain height and then flow into the dispersing tube 11, the cells are uniformly distributed into the inner cavity of the freezing and preserving bag body 1 through the holes of the dispersing tube 11, so that the cells in the freezing and preserving bag can be frozen into a very thin small borneol after the freezing and preserving is finished, the recovery time is shortened during recovery, the survival rate of the cells is improved, the first screw cap 6 is pulled out when the cells are taken out, the standard pipeline is connected to the top of the liquid outlet tube 5, the connecting position is not leaked, the strict requirements of the freezing and preserving tube operation on a place are eliminated, the freezing and preserving bag and the saline bag can be connected in a hospital dispensing environment.

It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a novel cell freezes deposits bag, includes freezes deposits bag body (1), its characterized in that: the utility model discloses a freezer bag, including freezer bag body (1), upper end fixed mounting of one side of freezer bag body (1) has label subsides (2), recess (3) have been seted up to the bottom of freezer bag body (1), the top fixed mounting of freezer bag body (1) has infusion pipe (4) and drain pipe (5), one end swing joint that freezer bag body (1) was kept away from to drain pipe (5) has first cap (6) soon, one end swing joint that freezer bag body (1) was kept away from to infusion pipe (4) has third cap (12), the middle part fixed mounting of infusion pipe (4) has connecting pipe (7), one end swing joint that infusion pipe (4) was kept away from to connecting pipe (7) has second cap (8) soon, the top fixed mounting of freezer bag body (1) inner chamber has fixed pipe (9), the bottom fixed mounting of fixed pipe (9) has extension pipe (10), the both sides fixed mounting of extension pipe (10) has dispersion pipe (11).

2. The novel cell cryopreservation bag according to claim 1, wherein: the dispersing pipe (11) is provided with a plurality of holes, and the sizes of the holes are the same.

3. The novel cell cryopreservation bag according to claim 1, wherein: the extension tube (10) is communicated with the dispersing tube (11), and the extension tube (10) and the dispersing tube (11) are provided with gaps along the inner cavity wall of the freezing storage bag body (1).

4. The novel cell cryopreservation bag according to claim 1, wherein: the second screw cap (8) and the first screw cap (6) are E-shaped.

5. The novel cell cryopreservation bag according to claim 1, wherein: the top of the label (2) is provided with a slotted hole, and the label (2) is made of transparent materials.

6. The novel cell cryopreservation bag according to claim 1, wherein: the material of the freezing bag body (1) is made of high polymer material EVA.

7. The novel cell cryopreservation bag according to claim 1, wherein: the first screw cap (6), the second screw cap (8) and the third screw cap (12) are made of rubber materials.