CN210085431U - Disposable erythrocyte-removing bone marrow collecting bag - Google Patents

Disposable erythrocyte-removing bone marrow collecting bag Download PDF

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Publication number
CN210085431U
CN210085431U CN201920832453.9U CN201920832453U CN210085431U CN 210085431 U CN210085431 U CN 210085431U CN 201920832453 U CN201920832453 U CN 201920832453U CN 210085431 U CN210085431 U CN 210085431U
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China
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bone marrow
bag
collection
anticoagulation
erythrocyte
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CN201920832453.9U
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Chinese (zh)
Inventor
张磊
孙恺
许芳
朱尊民
张琳
商保军
马国骍
李玉龙
邬成业
黄洲风
刘禄社
刘益民
程薇
董晓燕
程琳娜
李妍伸
李瞾博
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Henan Provincial Peoples Hospital
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Henan Provincial Peoples Hospital
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Abstract

The utility model discloses a disposable erythrocyte-removing bone marrow collecting bag, which comprises a first spiral connector, a second spiral connector, a first blood transfusion device socket, a second blood transfusion device socket, an anticoagulant bone marrow preserving bag, an erythrocyte collecting bag, a transfer catheter and a third switch device; the spiral connector I and the spiral connector II are respectively communicated with one end of the anticoagulation bone marrow preservation bag; the first blood transfusion device socket is communicated with the anticoagulation bone marrow preservation bag; the other end of the anticoagulation bone marrow preservation bag is communicated with one end of the transfer catheter, and the other end of the transfer catheter is communicated with one end of the erythrocyte collection bag; the second blood transfusion device socket is communicated with the red blood cell collecting bag; the third switching device is arranged on the transfer catheter. The utility model provides a collection bag is rational in infrastructure, convenient operation, low cost, both can make things convenient for clinical marrow to gather, can satisfy the technical requirement who gets rid of erythrocyte in the marrow blood again.

Description

Disposable erythrocyte-removing bone marrow collecting bag
Technical Field
The utility model relates to the technical field of medical equipment, concretely relates to disposable removes erythrocyte marrow and gathers bag.
Background
Currently, in the clinical operation of bone marrow transplantation, a disposable blood collection bag is used for collecting bone marrow, and the existing disposable blood collection bag generally comprises a closed blood collection needle, a catheter and an anticoagulation whole blood bag. The bone marrow is a connective tissue which is positioned in a bone marrow cavity and consists of a large number of hematopoietic stem cells, and can only be inserted into the bone marrow cavity by a clinician by using a bone marrow puncture needle and collected by suction of a syringe, the bone marrow is sucked into the syringe and then sleeved on a needle head, and the bone marrow is injected into an anticoagulation whole blood bag for preservation by puncturing a catheter of a disposable blood collection bag. However, during the process of sheathing the needle with the syringe and puncturing the blood collection bag tube, the fingers of the operator are easily injured or contaminants are easily introduced. In addition, a large amount of peripheral blood is mixed in the bone marrow during the suction, and in the case of allogeneic bone marrow transplantation with improper blood type, red blood cells and plasma in the bone marrow of a donor must be removed, or serious transfusion reaction and death of a recipient can be caused. The existing disposable blood collection bag can not be directly connected with an injector or can not meet the technical requirement of removing red blood cells, and brings inconvenience to clinical work.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a bag is gathered to disposable erythrocyte-removing marrow, gather bag rational in infrastructure, convenient operation, low cost, both can make things convenient for clinical marrow to gather, can satisfy the technical requirement who gets rid of erythrocyte in the marrow blood again.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the disposable erythrocyte-removing bone marrow collection bag comprises a first spiral connector, a second spiral connector, a first blood transfusion device socket, a second blood transfusion device socket, an anticoagulant bone marrow preservation bag, an erythrocyte collection bag, a transfer catheter and a third switch device; the spiral connector I and the spiral connector II are respectively communicated with one end of the anticoagulation bone marrow preservation bag; the first blood transfusion device socket is communicated with the anticoagulation bone marrow preservation bag; the other end of the anticoagulation bone marrow preservation bag is communicated with one end of the transfer catheter, and the other end of the transfer catheter is communicated with one end of the erythrocyte collection bag; the second blood transfusion device socket is communicated with the red blood cell collecting bag; the third switching device is arranged on the transfer catheter.
Furthermore, the disposable erythrocyte-removing bone marrow collection bag also comprises a collection catheter I, a collection catheter II, a switch device I and a switch device II; one end of the collection catheter I and one end of the collection catheter II are respectively communicated with one end of the anticoagulation bone marrow preservation bag, and the other end of the collection catheter I and the other end of the collection catheter II are respectively provided with a spiral connector I and a spiral connector II; the first switch device and the second switch device are respectively arranged on the first collecting conduit and the second collecting conduit.
Furthermore, the anticoagulation bone marrow preservation bag is in a slender shape.
Still more preferably, the anticoagulant bone marrow preservation bag has an aspect ratio of 30: 7.
Still further preferably, the anticoagulation bone marrow preservation bag has a length of 30cm and a width of 7 cm.
Furthermore, two ends of the anticoagulation bone marrow preservation bag are respectively provided with a hanging hole.
Furthermore, two ends of the erythrocyte collecting bag are respectively provided with a hanging hole.
Furthermore, the other end of the anticoagulation bone marrow preservation bag is provided with a shrinkage funnel, the inner diameter of the shrinkage funnel gradually shrinks along the output direction of the erythrocytes, and the output end of the shrinkage funnel is communicated with one end of the transfer catheter.
Furthermore, a dropping funnel is arranged on the transfer conduit.
The beneficial effects of the utility model reside in that: the utility model provides a collection bag is rational in infrastructure, convenient operation, low cost, both can make things convenient for clinical marrow to gather, can satisfy the technical requirement who gets rid of erythrocyte in the marrow blood again.
Drawings
Fig. 1 is a schematic view of a structure of a collecting bag in embodiment 1 of the present invention.
Detailed Description
The present invention will be further described with reference to the accompanying drawings, and it should be noted that the present embodiment is based on the technical solution, and the detailed embodiments and the specific operation processes are provided, but the protection scope of the present invention is not limited to the present embodiment.
Example 1
The embodiment provides a disposable erythrocyte-removing bone marrow collection bag, as shown in fig. 1, which comprises a first spiral connector 2, a second spiral connector 7, a first collection conduit 3, a second collection conduit 9, a first switch device 4, a second switch device 6, a first blood transfusion device socket 5, a second blood transfusion device socket 17, an anticoagulation bone marrow preservation bag 11, an erythrocyte collection bag 19, a transfer conduit 15 and a third switch device 16; one end of the collection conduit I3 and one end of the collection conduit II 9 are respectively communicated with one end of the anticoagulation bone marrow preservation bag 11, and the other end of the collection conduit I3 and one end of the collection conduit II 9 are respectively provided with a spiral joint I2 and a spiral joint II 7; the first switching device 4 and the second switching device 6 are respectively arranged on the first collecting conduit 3 and the second collecting conduit 9; the first blood transfusion device socket 5 is communicated with the anticoagulation bone marrow preservation bag 11; the other end of the anticoagulation bone marrow preservation bag 11 is communicated with one end of the transfer catheter 15, and the other end of the transfer catheter 15 is communicated with one end of the erythrocyte collection bag 19; the second blood transfusion device socket 17 is communicated with the red blood cell collecting bag 19; the third switching device 16 is arranged on the transfer catheter 15; the anticoagulant is stored in the anticoagulant bone marrow storage bag.
Further, in the present embodiment, the first screw joint 2 and the second screw joint 7 both adopt a winged female screw joint.
In this embodiment, the first switching device and the second switching device both use a switching clip. The third switching device 16 employs a flow regulator.
Further, in this embodiment, the anticoagulated bone marrow preservation bag 11 is elongated. The long anticoagulation bone marrow preservation bag 11 can increase the sedimentation distance of the red blood cells and the bone marrow stem cells in the bone marrow blood, and enhance the convection effect that the red blood cell mass is sedimented downwards to push the bone marrow stem cells to move upwards, thereby better separating the red blood cells and the bone marrow stem cells.
Preferably, the anticoagulant bone marrow preservation bag 11 has an aspect ratio of 30:7 (about 4.28: 1).
Further preferably, the length is 30cm and the width is 7 cm. The reason is that the clear height in the super clean bench is about 50 cm, the length of the anticoagulation bone marrow preservation bag is designed to be 30cm to be more appropriate except the upper end suspension space and the lower end space away from the bench surface, and the separation effect is better when the erythrocyte sedimentation distance is required to be more than 25 cm. After the length is fixed, the total volume is required to be at least more than 300 cubic centimeters to meet the technical requirements (about 50 milliliters of anticoagulant is stored in the bag, at least 200 milliliters of bone marrow blood is finally required to enter, and about 70 milliliters of hydroxyethyl starch is required to enter), so the width of the bag body is designed to be 7 centimeters, and the maximum volume of the whole anticoagulated bone marrow storage bag can be ensured to be 385 cubic centimeters.
Further, in this embodiment, one end of each anticoagulation bone marrow preservation bag 11 is provided with a hanging hole one 10. The first hanging hole 10 can be used for conveniently hanging the anticoagulation bone marrow preservation bag 11 in an ultra-clean workbench to enable the anticoagulation bone marrow preservation bag to be perpendicular to the workbench surface when bone marrow blood is collected, separated and settled.
Furthermore, in this embodiment, the blood transfusion device socket one 5 is communicated with one end of the anticoagulation bone marrow preservation bag 11, and the other end of the anticoagulation bone marrow preservation bag 11 is provided with a hanging hole two 13. Since the first blood transfusion device insertion opening 5 is communicated with one end of the anticoagulation bone marrow preservation bag 11, the second hanging hole 13 can play a role in conveniently hanging the anticoagulation bone marrow preservation bag 11 and enabling the first blood transfusion device insertion opening 5 to face downwards when the bone marrow stem cells are transfused to a bone marrow transplant recipient.
Further, in this embodiment, two ends of the red blood cell collecting bag 19 are respectively provided with a hanging hole three 18 and a hanging hole four 20.
In this embodiment, the second blood transfusion device insertion opening 17 is disposed at one end of the red blood cell collecting bag 19, and the hanging hole four 20 can help to hang the red blood cell collecting bag 19 and make the second blood transfusion device insertion opening 17 face downward when red blood cells are transfused.
Further, in this embodiment, the other end of the anticoagulation bone marrow preservation bag 11 is provided with a shrink funnel 12, the inner diameter of the shrink funnel 12 gradually shrinks along the output direction of the red blood cells, and the output end of the shrink funnel 12 is communicated with one end of the transfer catheter 15. During the red blood cell releasing and transferring process, the shrinking funnel 12 can shrink the interface between red blood cells and the bone marrow stem cell layer, so that the bone marrow stem cells can be more accurately intercepted, and the loss of the bone marrow stem cells is reduced. When the length of the anticoagulation bone marrow preservation bag 11 is set to 30cm and the width is 7cm, the height of the shrink funnel is preferably set to 8 cm.
Further, in this embodiment, a dropping funnel 14 is also provided on the transfer conduit. The flow rate of the red blood cells can be visually adjusted by the drip chamber 14.
Further, in the present embodiment, the first screw connector 2 and the second screw connector 7 are respectively connected with a first screw cap 1 and a second screw cap 8 which are matched with each other. Can keep the closure of winged female spiral joint when not using through the spiral helmet, keep connecting clean, and avoid the extraneous substance to get into in the collection pipe through connecting. When in use, the first spiral protective cap 1 and the second spiral protective cap 8 are unscrewed from the first spiral connector 2 and the second spiral connector 7.
Example 2
This example provides a method of using the single use, de-erythrocytic bone marrow collection bag of example 1, comprising the steps of:
the screw joint I2 is directly connected with an injector for pumping bone marrow, and a switching device I4 is turned on; directly injecting the bone marrow blood into an anticoagulation bone marrow preservation bag 11 through a first collection catheter 3 by a syringe; switching device two 6 and switching device three 16 remain closed;
thus, the operation doctor can be prevented from sleeving the syringe with the needle again to puncture the catheter, and the fingers of the operation doctor can be prevented from being punctured or pollutants can be prevented from being brought in; the first switch device 4 and the second switch device 6 are used for adjusting the opening and closing of the first collection conduit 3 and the second collection conduit 9, and bone marrow blood backflow is avoided. The third switch device 16 is used for adjusting the opening and closing of the transfer catheter 15, and preventing the bone marrow blood from directly entering the red blood cell collecting bag 19 without being separated.
The first spiral connector 2 is connected with an injector for injecting hydroxyethyl starch, the hydroxyethyl starch is injected into the anticoagulation bone marrow preservation bag 11 through the first collection catheter 3, and then the first switch device 4 is closed; erythrocyte aggregates in the marrow blood subside downwards under the action of hydroxyethyl starch, and marrow stem cells move upwards; suspending the anticoagulation bone marrow preservation bag in an ultraclean workbench, enabling the other end of the anticoagulation bone marrow preservation bag to face downwards, and under the action of gravity, generating an extrusion effect in the process that the erythrocyte mass acted by hydroxyethyl starch moves downwards, so that the marrow stem cells move upwards until the sedimentation effect stops (about 1-2 hours), and keeping the interface of the erythrocyte and the marrow stem cells constant and not changing any more;
after the erythrocyte pellet and the bone marrow stem cells are separated, the switch device III 16 is slowly opened, the erythrocytes are released and transferred into the erythrocyte collecting bag 19 drop by drop through the transfer catheter 15, and the switch device III 16 is closed after the completion of the release and transfer of the erythrocytes is observed. When the third switching device 16 adopts a flow regulator, the marrow stem cells can be accurately intercepted, so that the loss of the marrow stem cells is reduced while the retention of red blood cells is reduced.
The injector for sucking the upper plasma layer is connected with the second spiral connector 7, and the upper plasma layer is directly sucked out of the anticoagulation bone marrow preservation bag 11 through the second collection tube 9, so that the use of a blood plasma separation clamp is avoided, and the manual plasma extrusion is also avoided.
After the plasma is pumped, the plasma can be connected with an injector for injecting normal saline through a second spiral connector 7, and the normal saline is injected into an anticoagulation bone marrow preservation bag 11 through a second collection tube 9 for resuspending bone marrow stem cells;
sealing and cutting the first collection catheter 3, the second collection catheter 9 and the transfer catheter 15 by using a heat sealing machine, and infusing the bone marrow stem cells to a bone marrow transplant recipient through the first blood transfusion device socket 5; the red blood cells are returned to the bone marrow transplant donor through the second blood transfusion device spigot 17 or used for other purposes as required.
Various corresponding changes and modifications can be made by those skilled in the art according to the above technical solutions and concepts, and all such changes and modifications should be included in the protection scope of the present invention.

Claims (9)

1. The disposable erythrocyte-removing bone marrow collection bag is characterized by comprising a first spiral connector, a second spiral connector, a first blood transfusion device socket, a second blood transfusion device socket, an anticoagulant bone marrow preservation bag, an erythrocyte collection bag, a transfer catheter and a third switch device; the spiral connector I and the spiral connector II are respectively communicated with one end of the anticoagulation bone marrow preservation bag; the first blood transfusion device socket is communicated with the anticoagulation bone marrow preservation bag; the other end of the anticoagulation bone marrow preservation bag is communicated with one end of the transfer catheter, and the other end of the transfer catheter is communicated with one end of the erythrocyte collection bag; the second blood transfusion device socket is communicated with the red blood cell collecting bag; the third switching device is arranged on the transfer catheter.
2. The single-use erythrocytic bone marrow collection bag of claim 1 further comprising a collection conduit one, a collection conduit two, a switch device one, a switch device two; one end of the collection catheter I and one end of the collection catheter II are respectively communicated with one end of the anticoagulation bone marrow preservation bag, and the other end of the collection catheter I and the other end of the collection catheter II are respectively provided with a spiral connector I and a spiral connector II; the first switch device and the second switch device are respectively arranged on the first collecting conduit and the second collecting conduit.
3. The single use, erythrocyted bone marrow collection bag of claim 1, wherein said anticoagulated bone marrow preservation bag is elongated.
4. The single use, de-erythrocytic bone marrow collection bag of claim 3, wherein the anti-coagulated bone marrow preservation bag has an aspect ratio of 30: 7.
5. The single use, erythrocytic bone marrow harvest bag of claim 4 wherein the anticoagulated bone marrow preservation bag is 30cm long and 7cm wide.
6. The single-use erythrocyte-free bone marrow collection bag according to claim 1, wherein the anticoagulation bone marrow preservation bag is provided with hanging holes at both ends thereof.
7. The single-use erythrocytic bone marrow collection bag according to claim 1, wherein the two ends of the erythrocyte collection bag are respectively provided with a hanging hole.
8. The single-use erythrocytic bone marrow harvesting bag according to claim 1, wherein the other end of the anticoagulation bone marrow preservation bag is provided with a shrink funnel, the inner diameter of the shrink funnel gradually shrinks along the output direction of the erythrocytes, and the output end of the shrink funnel is communicated with one end of the transfer catheter.
9. The single use, erythrocytic bone marrow collection bag of claim 1 wherein a drip chamber is further provided on the transfer catheter.
CN201920832453.9U 2019-06-04 2019-06-04 Disposable erythrocyte-removing bone marrow collecting bag Active CN210085431U (en)

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CN201920832453.9U CN210085431U (en) 2019-06-04 2019-06-04 Disposable erythrocyte-removing bone marrow collecting bag

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Application Number Priority Date Filing Date Title
CN201920832453.9U CN210085431U (en) 2019-06-04 2019-06-04 Disposable erythrocyte-removing bone marrow collecting bag

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110093253A (en) * 2019-06-04 2019-08-06 河南省人民医院 It is disposable to go red blood cell bone marrow collection bag and method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110093253A (en) * 2019-06-04 2019-08-06 河南省人民医院 It is disposable to go red blood cell bone marrow collection bag and method

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