CN220747788U - Full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation - Google Patents

Full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation Download PDF

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Publication number
CN220747788U
CN220747788U CN202321683251.5U CN202321683251U CN220747788U CN 220747788 U CN220747788 U CN 220747788U CN 202321683251 U CN202321683251 U CN 202321683251U CN 220747788 U CN220747788 U CN 220747788U
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sampling
nucleic acid
chamber
detection
sample
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郭金成
丁艳蕊
王珊
金熙伟
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CHONGQING HAIRUN ENERGY-SAVING TECHNOLOGY CO LTD
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CHONGQING HAIRUN ENERGY-SAVING TECHNOLOGY CO LTD
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Abstract

The utility model discloses a full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation which comprises a movable board room, wherein a plurality of unit compartments are sequentially arranged from left to right, each unit compartment is a sampling chamber, a sampling test tube feeding chamber, a sample preparation chamber and a detection and sample processing chamber from left to right, a transfer mechanism is arranged between every two adjacent unit compartments, the sampling test tube feeding chamber, the sample preparation chamber and the detection and sample processing chamber are all closed spaces, partition wall transmission holes are formed in the wall bodies of each unit compartment corresponding to the transfer mechanism, the transfer mechanism comprises a conveyor belt which is positioned at the bottoms of the partition wall transmission holes and extends leftwards and rightwards, and an airtight door which is arranged in the partition wall transmission holes and divides the conveyor belt into two sections of conveyor belts. The nucleic acid detection and analysis can be carried out by self-help collection of nucleic acid, the transfer to other places is not needed, the infection generated in the transfer process is avoided, and meanwhile, the nucleic acid sample collected from other places can be received for detection.

Description

Full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation
Technical Field
The utility model relates to the technical field of medical detection equipment, in particular to a full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation.
Background
New coronaries are serious public health hazards and even national security, and are the most serious challenges facing human survival in the new century. The novel coronavirus nucleic acid detection of large-scale crowds such as close-fitting is developed, and the novel coronavirus nucleic acid detection has great practical significance and profound historical significance for early detection, definite target, definite direction, effective response, safety guarantee, reworking and reproduction, economy recovery and economic and social development promotion.
However, in the existing sample collection and detection process, because of the problems of intensive personnel crossing, complicated procedure, untight protection, link separation, aging delay and the like, particularly the most common pharyngeal swab sampling and other methods, the problems of high risk of cross infection in the collection process, uneven collection method due to artificial factors, storage of collected sample delivery and the like exist, and the safety and efficiency of virus detection are greatly affected.
Disclosure of Invention
The utility model aims to solve the technical problems in the prior art, and particularly creatively provides a full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation which can collect nucleic acid by self and directly carry out nucleic acid detection and analysis, does not need to be transported to other places, does not cause infection in the transportation process, and can also receive and detect nucleic acid samples collected from other places.
In order to achieve the above purpose, the utility model provides a full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation, which comprises a movable board house, wherein a plurality of unit compartments are sequentially arranged from left to right, the unit compartments are a sampling chamber, a sampling tube feeding chamber, a sample preparation chamber and a detecting and sample processing chamber from left to right, a transmission mechanism is arranged between two adjacent unit compartments, the sampling tube feeding chamber, the sample preparation chamber and the detecting and sample processing chamber are all closed spaces, partition wall transmission holes are arranged on the wall body of each unit compartment corresponding to the transmission mechanism, the transmission mechanism comprises a conveyor belt which is positioned at the bottom of the partition wall transmission hole and extends leftwards and rightwards, and an airtight door which is arranged in the partition wall transmission hole and divides the conveyor belt into two sections of conveyor belts;
a first photoelectric sensor and a second photoelectric sensor which are fixed by a bracket are arranged beside the conveying belt, and the first photoelectric sensor and the second photoelectric sensor are respectively arranged on two sides of the wall body, are respectively used for automatically identifying whether materials exist on the material starting position and the material ending position of the two-section conveying belt and are linked with the two-section conveying belt driving mechanism;
the automatic code printing machine is characterized in that a sampling pipe automatic code printing machine used for pasting information of personnel to be detected and a nucleic acid sampling robot with a face recognition function are arranged in the sampling chamber, the nucleic acid sampling robot is enclosed in a right corner of the sampling chamber through an isolation enclosing plate so as to be separated from other areas, the areas are sampling areas, the other areas are sampling pipe preparation areas, a house entrance door is arranged on a board room wall of the sampling pipe preparation area, a sampling pipe rack feeding module used for transmitting the sampling pipe is connected between the sampling pipe preparation area and the sampling area, a sampling window is formed in the board room wall of the sampling area, an intelligent all-in-one machine used for man-machine interaction is further arranged on the sampling window, the intelligent all-in-one machine is electrically connected with an intelligent server, and a data transmission end of the automatic code printing machine of the sampling pipe is connected with a data transmission end of the intelligent all-in-one machine;
the sample tube feeding chamber is internally provided with a transmission mechanism for connecting transmission mechanisms at the left side and the right side, an outward sample transmission window in a normally closed state is arranged on a board room wall body of the sample tube feeding chamber, and a nucleic acid sample collected elsewhere is placed on the transmission mechanism through the outward sample transmission window.
In the scheme, the method comprises the following steps: a nucleic acid extraction instrument upper/lower material arm, a nucleic acid extraction instrument arranged around the nucleic acid extraction instrument upper/lower material arm and a liquid transferring/film sealing device are arranged in the sample preparation chamber, and the sample extracted by the nucleic acid extraction instrument, the separated waste liquid and the sampling tube waste material are moved to a transmission mechanism between the sample preparation chamber and the detection and sample processing chamber through the nucleic acid extraction instrument upper/lower material arm;
the detection and specimen processing chamber is internally provided with a PCR (polymerase chain reaction) feeding/discharging arm, a PCR detector, a specimen temporary storage rack and an autoclave, wherein the PCR detector, the specimen temporary storage rack and the autoclave are arranged around the PCR feeding/discharging arm, a detection result data transmitting end of the PCR detector is connected with a detection result data receiving end of the intelligent integrated machine, a right side plate room wall body of the detection and specimen processing chamber is provided with an installation opening for embedding and installing the autoclave, a discharge outlet of the autoclave is positioned outside the movable plate room, and a sterilized article transfer module is connected between the specimen temporary storage rack and the autoclave;
the sampling tube preparation area is internally provided with a sampling tube rack support and a sampling tube rack feeding arm, the sampling tube rack is placed on a sampling tube rack feeding module through the sampling tube rack feeding arm, a transmission mechanism between the sampling area and a sampling tube feeding chamber is a sampling tube rack discharging module, and a sampling conveyor belt is connected between the sampling tube rack discharging module and the sampling tube rack feeding module;
the transfer mechanism between sampling test tube material loading room and the sample preparation room is for waiting to examine sampling pipe support ejection of compact module, the indoor sample transfer window that corresponds to send out of sampling test tube material loading is equipped with and sends out the sampling pipe support, send out the sampling pipe support and wait to examine and be connected with between sampling pipe support ejection of compact module and send out the sampling pipe support conveyer belt.
In the scheme, the method comprises the following steps: the sample preparation room is also communicated with a consumable and equipment preparation room, a consumable support and a consumable material taking arm are arranged in the consumable and equipment preparation room, a consumable material feeding module is communicated between the consumable and equipment preparation room and the sample preparation room, and consumables on the consumable support are placed on the consumable material feeding module through the consumable material taking arm;
the sample preparation room corresponds consumptive material pay-off module and waits to examine sample pipe support ejection of compact module and all is provided with the pay-off conveyer belt, the transfer mechanism between sample preparation room and the detection and the sample processing room includes PCR pay-off module, waste material transfer module and sampling pipe waste material transmission module, the discharge end and the PCR pay-off module intercommunication of pipetting/envelope equipment, the end of PCR pay-off module and the end of sampling pipe waste material transmission module all stretch to in the detection and the sample processing room, send respectively sample and the sampling pipe waste material that seals up to detect and the sample processing room through PCR pay-off module and sampling pipe waste material transmission module and handle.
In the scheme, the method comprises the following steps: sampling test tube material loading room and consumptive material and equipment preparation room set up in same unit compartment to the front and back next-door neighbour sets up, the sampling area also sets up the front side at the sampling room, rational utilization space.
In the scheme, the method comprises the following steps: and the board house walls of the sampling area, the sampling test tube feeding chamber, the sample preparation chamber and the detection and sample treatment chamber are all provided with overhaul holes, so that workers can conveniently enter the room for overhaul.
In the scheme, the method comprises the following steps: the movable sun shading device is arranged outside the sampling window, so that people who detect nucleic acid can conveniently shade rain and sun.
In the scheme, the method comprises the following steps: the left side of sampling room still is equipped with the equipment room, intelligent server sets up in the equipment room, all is equipped with supervisory equipment in every unit compartment, and all supervisory equipment's monitoring data all transmits to the equipment room, be equipped with the door of registering one's residence between the equipment.
In the scheme, the method comprises the following steps: ultraviolet sterilizing lamps are arranged on the upper side, the left side and the right side of the two ends of the orifice of the partition wall transmission hole, and the orifice end with high air pressure of the partition wall transmission hole is an air curtain machine arranged above one side of the material starting position; the air curtain machine is used for air isolation and plays a double isolation role on the basis of isolating a high-pressure room from a low-pressure room.
In the scheme, the method comprises the following steps: the conveying belt is a two-section conveying belt and is respectively arranged at two sides of the wall body;
the transmission belt includes: the two-section type conveying belt is arranged below the two-section type conveying belt and is provided with a working mechanism and a two-section type conveying belt bracket.
In the scheme, the method comprises the following steps: the airtight door is provided with a limit switch, so that the safety of the airtight door motor is protected; the airtight door and the two-section type transmission belt are both provided with control buttons which can forcedly change the working state.
In summary, due to the adoption of the technical scheme, the beneficial effects of the utility model are as follows: the nucleic acid sampling robot and the intelligent integrated machine can be used for self-help sampling, and the nucleic acid sampling robot with the face recognition function can avoid false detection; the transfer gate, the sampling area, the sampling test tube feeding chamber, the sample preparation chamber and the detection and sample processing chamber which are arranged in a normally closed manner can ensure that the nucleic acid collection, extraction and detection system adopts a fully-automatic fully-closed sample inlet and result outlet mode as far as possible, avoid misoperation as far as possible and reduce personnel infection risk; the detection can be performed after the collection is finished without transferring to other detection mechanisms, so that the detection efficiency is improved; after the detection is finished, sterilization and disinfection are immediately carried out, and the safety performance is not lower than that of the clinical conventional nucleic acid detection and POCT (point of care testing) closed detection, so that pollution prevention and low or no biological safety hazard are realized.
Drawings
The foregoing and/or additional aspects and advantages of the utility model will become apparent and may be better understood from the following description of embodiments taken in conjunction with the accompanying drawings in which:
FIG. 1 is a schematic view of a portable housing of the present utility model;
FIG. 2 is a schematic diagram of the structure of the present utility model;
fig. 3 is a schematic structural view of a transmission mechanism of the present utility model.
Fig. 4 is a schematic front view of the transmission mechanism of the present utility model.
Fig. 5 is a flow chart of the operation of the transfer mechanism of the present utility model.
Fig. 6 is a schematic diagram of a two-stage belt portion control of the present utility model.
Fig. 7 is a schematic diagram of the airtight door control according to the present utility model.
Fig. 8 is a schematic diagram of the air curtain control of the present utility model.
Detailed Description
Embodiments of the present utility model are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the utility model.
As shown in fig. 1-2, a full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation comprises a movable board house which is sequentially provided with a plurality of unit compartments from left to right. The unit compartments are a sampling chamber, a sampling tube feeding chamber S7, a sample preparation chamber S4 and a detection and sample processing chamber S5 from left to right in sequence, and a transmission mechanism which can only transmit the collected nucleic acid sample from the left unit compartment to the right unit compartment is arranged between two adjacent unit compartments. The sampling tube feeding chamber S7, the sample preparation chamber S4 and the detection and sample processing chamber S5 are all closed spaces. In order to ensure stable transfer of nucleic acid samples, partition wall transmission holes A10 are formed in the wall bodies shared by adjacent unit compartments and correspond to the transmission mechanisms, the transmission mechanisms comprise transmission belts which are positioned at the bottoms of the partition wall transmission holes A10 and extend leftwards and rightwards, and air-tight doors A1 which are arranged in the partition wall transmission holes A10 and divide the transmission belts into two sections of transmission belts A5; only when the nucleic acid sample is transferred, the air circulation between the unit compartments is reduced, and cross infection is avoided. In order to further avoid cross infection, ultraviolet sterilizing lamps A4 are arranged on the upper side, the left side and the right side of the two ends of the orifice of the partition wall transmission hole A10, and an air curtain A3 is arranged above the orifice end with high air pressure of the partition wall transmission hole A10. The airtight door A1 is provided with a limit switch, the safety of a motor of the airtight door A1 is protected, and the joint of the airtight door A1 and the partition wall transmission hole A10 is made of polyurethane rubber materials.
The photoelectric sensor A8 and the photoelectric sensor B11 which are fixed through the support A9 are arranged beside the conveying belt, the photoelectric sensor A8 and the photoelectric sensor B11 are respectively arranged on two sides of the wall body, are respectively used for automatically identifying whether materials exist on the material starting position A6 and the material ending position A12 of the two-section conveying belt A5 and are linked with the two-section conveying drive actuating mechanism A7.
The transmission belt is a two-section transmission belt A5 which is respectively arranged at two sides of the wall body; the transmission belt includes: the two-section conveyor belt is arranged below the two-section conveyor belt A5, and comprises a driving mechanism A7 and a two-section conveyor belt bracket A13.
The nucleic acid sampling robot 4 with the face recognition function is arranged in the sampling chamber, and the nucleic acid sampling robot 4 is enclosed in the corner on the front right side of the sampling chamber through the isolation enclosing plate so as to be separated from other areas, wherein the areas are sampling areas S6 and other areas are sampling tube preparation areas S2. The house door J1 is arranged on the board house wall of the sampling tube preparation area S2, and a sampling tube rack feeding module 24 for conveying sampling tubes is connected between the sampling tube preparation area S2 and the sampling area S6, so that medical staff can manually prepare the sampling tubes in the sampling tube preparation area S2 and then transfer the sampling tubes to the sampling area S6 to supply collecting consumables. Correspondingly, the two ends of the sampling pipe rack feeding module 24 are also provided with transfer doors.
Preferably, the sampling tube preparation area S2 is also internally provided with a sampling tube rack support 23 and a sampling tube rack feeding arm 25, and the sampling tube rack 26 is automatically placed on the sampling tube rack feeding module 24 through the sampling tube rack feeding arm 25, so that the degree of automation is improved, the manual investment is further reduced, and the protection effect is improved.
The front side of sampling area S6 has offered sampling window, still is equipped with the intelligent all-in-one 3 that is used for human-computer interaction on the sampling window, and intelligent all-in-one 3 electricity is connected with intelligent server 1. The sampling area S6 is also internally provided with an automatic sampling pipe coding machine 2, the data transmission end of the automatic sampling pipe coding machine 2 is connected with the data transmission end of the intelligent integrated machine 3, and the automatic sampling pipe coding machine 2 is used for pasting the information of the personnel to be detected acquired from the intelligent integrated machine 3 on the sampling pipe. The automatic coding machine 2 for sampling tubes is provided with a storage box for storing the sampling tubes.
The transmission mechanism between the sampling area S6 and the sampling test tube feeding chamber S7 is a sampling pipe rack discharging module 5, and a sampling conveyor belt is connected between the sampling pipe rack discharging module 5 and the sampling pipe rack feeding module 24.
When the nucleic acid is collected, the nucleic acid sampling robot 4 takes down the sampling tube with the information stuck on the automatic coding machine 2 of the sampling tube, and then the nucleic acid is collected. After the nucleic acid is collected, the sampling tube is placed on the sampling tube rack 26, and is conveyed to the sampling tube feeding chamber S7 through the sampling tube rack discharging module 5.
Be equipped with the transport mechanism who is used for connecting the transport mechanism of left and right sides in the sampling test tube material loading room S7, offered on the board house wall body of sampling test tube material loading room S7 and be in the sample transfer window J5 that send outward of normal close state, put on transport mechanism with the nucleic acid sample that gathers elsewhere through sending out sample transfer window J5. The transmission mechanism between the sampling test tube feeding chamber S7 and the sample preparation chamber S4 is a sampling tube rack discharging module 8 to be detected, an external sampling tube rack 6 is arranged in the sampling test tube feeding chamber S7 corresponding to the external sample transmission window J5, and an external sampling tube rack transmission belt 7 is connected between the external sampling tube rack 6 and the sampling tube rack discharging module 8 to be detected.
Sample preparation room S4 still communicates there is consumptive material and equipment preparation room S3, is equipped with consumptive material support 21 and consumptive material in consumptive material and the equipment preparation room S3 and gets arm 22, and the intercommunication has consumptive material pay-off module 20 between consumptive material and the equipment preparation room S3 and the sample preparation room S4, gets arm 22 through the consumptive material and puts the consumptive material on the consumptive material support 21 on consumptive material pay-off module 20 voluntarily to in time supply consumptive material to sample preparation room S4.
Wherein, sampling test tube material loading room S7 and consumptive material and equipment preparation room S3 set up in same unit compartment to the front and back next-door neighbour sets up, and sampling area S6 also sets up the front side at the sampling room, rational utilization space.
And a feeding conveyor belt is arranged in the specimen preparation chamber S4 corresponding to the consumable feeding module 20 and the sampling pipe rack discharging module 8 to be detected. The sample preparation room S4 is internally provided with a nucleic acid extractor upper/lower arm 10 in the middle, and the left side of the nucleic acid extractor upper/lower arm 10 is provided with a nucleic acid extractor 9, and consumable materials on a feeding conveyor belt and sampling pipes to be detected are placed into the nucleic acid extractor 9 through the nucleic acid extractor upper/lower arm 10 to extract nucleic acid samples.
The right side of the upper/lower material arm 10 of the nucleic acid extraction instrument is provided with a liquid-transferring/film-sealing device 19, and a transfer mechanism between the sample preparation chamber S4 and the detection and sample processing chamber S5 comprises a PCR feeding module 18, a waste transfer module 11 and a sampling tube waste transmission module 12, wherein the discharge end of the liquid-transferring/film-sealing device 19 is communicated with the PCR feeding module 18. The end of the PCR feeding module 18 and the end of the sample tube waste transfer module 12 both extend into the detection and sample processing chamber S5. After the nucleic acid extraction instrument 9 extracts the specimen, the separated waste liquid and the sampling tube waste are correspondingly moved to the pipetting/sealing film equipment 19, the waste transfer module 11 and the sampling tube waste transmission module 12 through the nucleic acid extraction instrument upper/lower feeding arm 10. After the specimen film is sealed, the sealed specimen and the sampling tube waste are respectively sent to a detection and specimen processing chamber S5 for processing through a PCR feeding module 18 and a sampling tube waste transmission module 12.
The detection and specimen processing chamber S5 is internally provided with a PCR (polymerase chain reaction) upper/lower material arm 14, a PCR detector 13, a specimen temporary storage rack 17 and an autoclave 16, wherein the PCR detector 13 is arranged around the PCR upper/lower material arm 14, a detection result data transmitting end of the PCR detector 13 is connected with a detection result data receiving end of the intelligent integrated machine 3, a right side plate room wall of the detection and specimen processing chamber S5 is provided with an installation opening for embedding and installing the autoclave 16, an exhaust port of the autoclave 16 is positioned outside a movable plate room, and a sterilization article transfer module 15 is connected between the specimen temporary storage rack 17 and the autoclave 16.
In order to ensure stable operation of the equipment, the access holes J4 are preferably formed in the board house walls of the sampling area S6, the sampling test tube feeding chamber S7, the sample preparation chamber S4 and the detection and sample treatment chamber S5, so that workers can conveniently enter the room for maintenance at regular time.
Preferably, the movable sunshade device J2 is arranged outside the sampling window, so that people for detecting nucleic acid can conveniently shade rain and sun.
The left side of the sampling room is also provided with an equipment room S1, the intelligent server is arranged in the equipment room S1, monitoring equipment 27 is arranged in each unit room, monitoring data of all the monitoring equipment 27 are transmitted to the equipment room S1, and a door is arranged between the equipment rooms S1.
Before use, firstly, the sampling tube frames 26 are sequentially placed at the appointed positions on the sampling tube frame support 23 through manpower, the empty sampling test tubes are placed in the storage boxes in the automatic sampling tube coding machine 2, and meanwhile consumable materials are required to be sequentially placed at the appointed positions on the consumable material support 21.
The automatic sampling tube coding machine 2 automatically pastes an identification code on an empty sampling test tube according to the registration information of the person to be detected, and then automatically sends the identification code to the position of the nucleic acid sampling robot 4 for standby. The nucleic acid sampling robot 4 automatically and accurately collects the nucleic acid sample of the person to be detected according to the face recognition function on the arm thereof, and stores the sample in the empty sampling test tube sent by the automatic sampling tube coding machine 2, and then sequentially places the sample on the sampling tube rack 26.
The nucleic acid sampling robot 4 has the functions of single detection and mixed detection, and after the sampling pipe rack 26 at the position of the nucleic acid sampling robot 4 is full, the sampling pipe rack feeding module 24 sends the sampling pipe rack 26 to the sampling pipe rack discharging module 5.
If the sample pipe rack 6 is sent out, the sample pipe rack delivery window J5 is sequentially arranged on the sample pipe rack delivery device 7, the sample pipe rack discharging module 5 is linked with the sample pipe rack delivery device 7, and the sample pipe rack delivery device 7 automatically sequentially sends the sample pipe rack 26 and the sample pipe rack 6 to the sample pipe rack discharging module 8 to be detected and then is transferred to the side of the nucleic acid extractor 9 to be detected.
Consumable material taking arm 22 is transferred to the side of nucleic acid extraction instrument 9 for later use after automatic placing consumable material in the consumable material loading module 20 in consumable material support 21, and nucleic acid extraction instrument goes up/unloading arm 10 according to the order will deposit sampling pipe support 26/the outer sampling pipe support 6 of waiting to examine on sampling pipe support ejection of compact module 8, consumable material on the consumable material loading module 20 is put into nucleic acid extraction instrument 9 in proper order and is carried out nucleic acid extraction.
After the nucleic acid extraction apparatus 9 is operated, the nucleic acid extraction apparatus upper/lower arm 10 places the nucleic acid extraction solution in the nucleic acid extraction apparatus 9 at the pipetting/sealing device 19, transfers the sampling tube waste to the sampling tube waste transfer module 12, transfers the rest of the material to the waste transfer module 11, and transfers the sampling tube waste from the sampling tube waste transfer module 12 to the detection and specimen processing chamber S5 and from the PCR upper/lower arm 14 to the specimen temporary storage rack 17 for temporary storage. After the temporary storage time of the sampling tube waste is up, the sampling tube waste is placed on a sterilized article transfer module 15 by a PCR feeding/discharging arm 14 and is sent into an autoclave 16 for sterilization. The waste material transfer module 11 sends the materials used by the nucleic acid extractor 9 to the detection and specimen processing chamber S5, and the materials are transferred to the sterilizing article transfer module 15 by the PCR feeding/discharging arm 14 after being packaged, and then the materials are sent to the autoclave 16 for sterilization.
The pipetting/sealing film equipment 19 processes the nucleic acid extracting solution into a PCR plate, and then sends the PCR plate to the PCR detector 13 for detection through the PCR feeding module 18, and the PCR upper/lower arm 14 automatically sends the PCR plate on the PCR feeding module 18 to the PCR detector 13 for nucleic acid detection. The PCR loading/unloading arm 14 automatically transfers the PCR plate detected by the PCR detector 13 to the specimen temporary storage rack 17 for temporary storage, and the detected PCR plate is placed on the sterilizing article transfer module 15 by the PCR loading/unloading arm 14 after temporary storage time is up and then is sent into the autoclave 16 for sterilization.
The sterilized materials are automatically spit outdoors by the autoclave 16 and are classified and disposed by staff in time, the detection result of the PCR detector 13 is uploaded to a professional for analysis, and the analysis result is online and can be printed on the intelligent all-in-one machine 3 by a person to be detected.
Staff maintains and overhauls the equipment in the sampling area S6, the sample preparation room S4 and the detection and sample processing room S5 respectively through the glass window of the sampling room, the overhauling hole J3 and the overhauling hole J4, and ensures the stable operation of the equipment.
As shown in fig. 4 to 6, the utility model also comprises an operation control principle of the automatic material conveying equipment for the biosafety laboratory, wherein the operation control principle is as follows:
fig. 4 is a schematic diagram of a two-stage belt portion control according to the present utility model: the photoelectric sensor A8 detects material information, the normally open contact 1k is automatically closed, the contactor KM1 is electrified, and the normally open contact KM1 is automatically closed. When the photoelectric sensor A8 detects material information, the two-section type conveying belt A5 starts to convey materials; simultaneously, the contactor KM2 and the contactor KM3 are electrified, a normally open contact of the contactor KM2 is automatically closed, and a normally closed contact of the contactor KM3 is automatically closed;
when the photoelectric sensor II A11 detects material information, the normally closed contact 1k1 is automatically opened, the contactor KM1 loses power, and the KM1 contact is restored to the original state. When the photoelectric sensor II A11 detects material information, the two-section type transmission belt drives the actuating mechanism A7 to stop acting, and the two-section type transmission belt A5 stops; meanwhile, the contacts KM2 and KM3 lose power, and the contacts KM2 and KM3 recover the original state.
Wherein ZK is a main switch, SB1 is a start switch of a manual mode of the two-stage conveyor belt.
Fig. 7 is a schematic diagram of the airtight door control of the present utility model: when no external signal is applied, i.e. the photoelectric sensor does not detect the material, the contactor KM5 is electrified, the normally closed bipolar switch KM5 is in a closed state, the motor of the airtight door A1 works reversely, and the airtight door A1 starts to move downwards to be closed. When the airtight door A1 runs to the position of the limit switch contact SQ2, the limit switch contact SQ2 is opened, the contactor KM5 is powered off, the normally open contact of KM5 is automatically closed, and the normally closed contact is automatically opened; the normally closed bipolar switch KM5 is turned off, and the motor of the airtight door A1 stops moving.
When the photoelectric sensor A8 detects material information, after the contactor KM3 in FIG. 4 is electrified, a normally open contact of the KM3 is automatically closed, and a normally closed contact of the contactor is automatically opened; the contactor KM4 is electrified, the normally open bipolar switch KM4 is closed, the motor of the airtight door A1 rotates positively, and the airtight door A1 starts to move upwards to be opened. When the airtight door A1 moves to the position of the limit switch contact SQ1, the limit switch contact SQ1 is opened, the contactor KM4 is powered off, the normally open contact of KM4 is automatically closed, the normally closed contact is automatically opened, and the motor of the airtight door A1 stops moving.
In addition, control buttons SBS3 and SBS4 capable of forcedly controlling the opening and closing of the airtight door A1 are arranged, and when the control button SBS3 is pressed, the airtight door A1 is converted into reverse rotation from positive rotation; when the control button SBS4 is pressed, the airtight door A1 is changed from reverse rotation to forward rotation. SBS2 is a scram switch.
When the photoelectric sensor II A11 detects material information, in the figure 3, the contactor KM3 is powered off, the normally open contact of KM3 is in an open state, and the normally closed contact is in a closed state; the contactor KM5 is electrified, the normally-closed bipolar switch KM5 is closed, the motor of the airtight door A1 works reversely, the airtight door A1 is closed, when the airtight door A1 moves to the position of the limit switch contact SQ2, the limit switch contact SQ2 is opened, the contactor KM5 is powered off, the normally-open contact of the KM5 is automatically closed, and the normally-closed contact is automatically opened; the normally closed bipolar switch KM5 is turned off, and the motor of the airtight door A1 stops moving.
FIG. 8 is a schematic diagram of the air curtain control of the present utility model: when the contactor KM2 in the figure 3 is electrified, a normally open contact of the contactor KM2 is automatically closed, a power supply loop of the air curtain machine A3 is electrified, and the air curtain machine A3 is started; when the contactor KM2 is powered off, the contact KM2 is restored to the original state, the power supply loop of the air curtain machine A3 is powered off, and the air curtain machine A3 is closed. Wherein the circuit breakers are connected first.
While embodiments of the present utility model have been shown and described, it will be understood by those of ordinary skill in the art that: many changes, modifications, substitutions and variations may be made to the embodiments without departing from the spirit and principles of the utility model, the scope of which is defined by the claims and their equivalents.

Claims (10)

1. A full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation which is characterized in that: the device comprises a movable board house with a plurality of unit compartments sequentially arranged from left to right, wherein the unit compartments sequentially comprise a sampling chamber, a sampling test tube feeding chamber (S7), a sample preparation chamber (S4) and a detection and sample processing chamber (S5) from left to right, a transmission mechanism is arranged between two adjacent unit compartments, the sampling test tube feeding chamber (S7), the sample preparation chamber (S4) and the detection and sample processing chamber (S5) are all closed spaces, partition wall transmission holes (A10) are formed in the wall body of each unit compartment corresponding to the transmission mechanism, the transmission mechanism comprises a conveyor belt which is positioned at the bottom of the partition wall transmission hole (A10) and extends leftwards and rightwards, and an airtight door (A1) which is arranged in the partition wall transmission hole (A10) and divides the conveyor belt into two sections of transmission belts (A5);
a first photoelectric sensor (A8) and a second photoelectric sensor (A11) which are fixed by a bracket (A9) are arranged beside the conveying belt, the first photoelectric sensor (A8) and the second photoelectric sensor (A11) are respectively arranged on two sides of a wall body, are respectively used for automatically identifying whether materials exist on a material starting position (A6) and a material ending position (A12) of the two-section conveying belt (A5) and are linked with a two-section conveying belt actuating mechanism (A7);
the automatic sampling tube coding machine is characterized in that a sampling tube automatic coding machine (2) used for attaching information of personnel to be detected and a nucleic acid sampling robot (4) with a face recognition function are arranged in the sampling chamber, the nucleic acid sampling robot (4) is enclosed in a right corner of the sampling chamber through an isolation enclosing plate so as to be separated from other areas, the area is a sampling area (S6), the other areas are sampling tube preparation areas (S2), a house entrance door (J1) is arranged on a board room wall body of the sampling tube preparation areas (S2), a sampling tube rack feeding module (24) used for transmitting the sampling tubes is connected between the sampling tube preparation areas (S2) and the sampling area (S6), a sampling window is formed in the board room wall body of the sampling area (S6), an intelligent all-in-one machine (3) used for man-machine interaction is further arranged on the sampling window, the intelligent all-in-one machine (3) is electrically connected with an intelligent server (1), and a data transmission end of the automatic coding machine (2) is connected with a data transmission end of the intelligent all-in-one machine (3);
the sampling test tube feeding chamber (S7) is internally provided with a transmission mechanism for connecting transmission mechanisms at the left side and the right side, a normally-closed outward-conveying sample transmission window (J5) is formed in a board room wall body of the sampling test tube feeding chamber (S7), and a nucleic acid sample collected elsewhere is placed on the transmission mechanism through the outward-conveying sample transmission window (J5).
2. The fully automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein: a nucleic acid extraction instrument upper/lower arm (10), a nucleic acid extraction instrument (9) and a liquid transferring/film sealing device (19) which are arranged around the nucleic acid extraction instrument upper/lower arm (10) are arranged in the sample preparation chamber (S4), and the sample extracted by the nucleic acid extraction instrument (9), separated waste liquid and sampling tube waste materials are moved to a transmission mechanism between the sample preparation chamber (S4) and the detection and sample processing chamber (S5) through the nucleic acid extraction instrument upper/lower arm (10);
the detection and specimen processing chamber (S5) is internally provided with a PCR (polymerase chain reaction) feeding/discharging arm (14) and a PCR detector (13), a specimen temporary storage rack (17) and an autoclave (16) which are arranged around the PCR feeding/discharging arm (14), a detection result data transmitting end of the PCR detector (13) is connected with a detection result data receiving end of the intelligent integrated machine (3), a right side plate house wall of the detection and specimen processing chamber (S5) is provided with an installing port for embedding and installing the autoclave (16), an exhaust port of the autoclave (16) is positioned outside the movable plate house, and a sterilization article transfer module (15) is connected between the specimen temporary storage rack (17) and the autoclave (16);
a sampling pipe rack support (23) and a sampling pipe rack feeding arm (25) are arranged in the sampling pipe rack preparation area (S2), a sampling pipe rack (26) is placed on a sampling pipe rack feeding module (24) through the sampling pipe rack feeding arm (25), a transmission mechanism between the sampling area (S6) and a sampling test tube feeding chamber (S7) is a sampling pipe rack discharging module (5), and a sampling conveyor belt is connected between the sampling pipe rack discharging module (5) and the sampling pipe rack feeding module (24);
the conveying mechanism between the sampling test tube feeding chamber (S7) and the sample preparation chamber (S4) is a sampling tube rack discharging module (8) to be detected, an external sampling tube rack (6) is arranged in the sampling test tube feeding chamber (S7) corresponding to an external sample conveying window (J5), and an external sampling tube rack conveying belt (7) is connected between the external sampling tube rack (6) and the sampling tube rack discharging module (8) to be detected.
3. The fully automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 2, wherein: the sample preparation chamber (S4) is also communicated with a consumable and equipment preparation chamber (S3), a consumable support (21) and a consumable taking arm (22) are arranged in the consumable and equipment preparation chamber (S3), a consumable feeding module (20) is communicated between the consumable and equipment preparation chamber (S3) and the sample preparation chamber (S4), and consumables on the consumable support (21) are placed on the consumable feeding module (20) through the consumable taking arm (22);
the sample preparation room (S4) is interior corresponds consumptive material pay-off module (20) and wait to examine sample pipe support ejection of compact module (8) all to be provided with the pay-off conveyer belt, the transport mechanism between sample preparation room (S4) and detection and sample processing chamber (S5) includes PCR pay-off module (18), waste material transfer module (11) and sampling pipe waste material transmission module (12), the discharge end and the PCR pay-off module (18) intercommunication of pipetting/envelope equipment (19), in the end of PCR pay-off module (18) and the end of sampling pipe waste material transmission module (12) all stretched into detection and sample processing chamber (S5), sample and sampling pipe waste material that will seal up through PCR pay-off module (18) and sampling pipe waste material transmission module (12) are carried detection and sample processing chamber (S5) respectively and are handled.
4. A fully automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 3, characterized in that: the sampling test tube feeding chamber (S7) and the consumable and equipment preparation chamber (S3) are arranged in the same unit compartment and are arranged in the front-back close mode, and the sampling area (S6) is also arranged on the front side of the sampling chamber.
5. The fully automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein: and access holes (J4) are formed in the board house wall bodies of the sampling area (S6), the sampling test tube feeding chamber (S7), the sample preparation chamber (S4) and the detection and sample treatment chamber (S5).
6. The fully automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein: and a movable sunshade device (J2) is arranged outside the sampling window.
7. The fully automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein: the left side of sampling room still is equipped with equipment room (S1), intelligent server sets up in equipment room (S1), all is equipped with supervisory equipment (27) in every unit compartment, and the control data of all supervisory equipment (27) all transmits to equipment room (S1), equipment room (S1) is equipped with into door (J1).
8. The full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein ultraviolet sterilizing lamps (A4) are arranged on the upper side, the left side and the right side of two ends of an orifice of the partition wall transmission hole (a 10), and an air curtain machine (A3) is arranged above the orifice end with high air pressure of the partition wall transmission hole (a 10).
9. The full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein the conveyor belt is a two-section conveyor belt (A5) which is respectively arranged at two sides of the wall body;
the transmission belt includes: the two-section type conveyor belt acting mechanism (A7) and the two-section type conveyor belt bracket (A13) are arranged below the two-section type conveyor belt (A5).
10. The full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein the airtight door (A1) is provided with a limit switch, so that the safety of a motor of the airtight door (A1) is protected.
CN202321683251.5U 2023-06-29 2023-06-29 Full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation Active CN220747788U (en)

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