CN112263281A - Negative pressure transmission pathology examination full-flow system for infectious specimen - Google Patents
Negative pressure transmission pathology examination full-flow system for infectious specimen Download PDFInfo
- Publication number
- CN112263281A CN112263281A CN202011014353.9A CN202011014353A CN112263281A CN 112263281 A CN112263281 A CN 112263281A CN 202011014353 A CN202011014353 A CN 202011014353A CN 112263281 A CN112263281 A CN 112263281A
- Authority
- CN
- China
- Prior art keywords
- sample
- chamber
- sampling
- pathological
- specimen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000015181 infectious disease Diseases 0.000 title claims abstract description 27
- 230000005540 biological transmission Effects 0.000 title claims abstract description 25
- 230000002458 infectious effect Effects 0.000 title claims abstract description 22
- 230000007170 pathology Effects 0.000 title claims description 28
- 238000005070 sampling Methods 0.000 claims abstract description 104
- 230000001575 pathological effect Effects 0.000 claims abstract description 98
- 210000001835 viscera Anatomy 0.000 claims abstract description 40
- 238000011888 autopsy Methods 0.000 claims abstract description 33
- 230000014759 maintenance of location Effects 0.000 claims abstract description 32
- 238000012544 monitoring process Methods 0.000 claims abstract description 25
- 239000000463 material Substances 0.000 claims abstract description 24
- 210000000056 organ Anatomy 0.000 claims abstract description 21
- 238000000746 purification Methods 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 9
- 238000012545 processing Methods 0.000 claims description 30
- 238000011049 filling Methods 0.000 claims description 29
- 239000007788 liquid Substances 0.000 claims description 29
- 230000006698 induction Effects 0.000 claims description 21
- 238000011010 flushing procedure Methods 0.000 claims description 17
- 230000002779 inactivation Effects 0.000 claims description 17
- 238000002224 dissection Methods 0.000 claims description 14
- 208000035473 Communicable disease Diseases 0.000 claims description 13
- 238000004140 cleaning Methods 0.000 claims description 9
- 230000000712 assembly Effects 0.000 claims description 7
- 238000000429 assembly Methods 0.000 claims description 7
- 230000000249 desinfective effect Effects 0.000 claims description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- 230000001788 irregular Effects 0.000 claims description 4
- 238000004043 dyeing Methods 0.000 claims description 3
- 230000000415 inactivating effect Effects 0.000 claims description 3
- 244000005700 microbiome Species 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 238000003860 storage Methods 0.000 claims description 3
- 238000012546 transfer Methods 0.000 claims description 3
- 238000010171 animal model Methods 0.000 claims description 2
- 238000007689 inspection Methods 0.000 claims 1
- 210000003484 anatomy Anatomy 0.000 abstract description 29
- 238000005516 engineering process Methods 0.000 abstract description 12
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000007781 pre-processing Methods 0.000 description 3
- 238000009423 ventilation Methods 0.000 description 3
- 241000700605 Viruses Species 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 208000019693 Lung disease Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000000834 fixative Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B16/00—Devices specially adapted for vivisection or autopsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G13/00—Operating tables; Auxiliary appliances therefor
- A61G13/0027—Autopsy, embalming or morgue tables
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G15/00—Conveyors having endless load-conveying surfaces, i.e. belts and like continuous members, to which tractive effort is transmitted by means other than endless driving elements of similar configuration
- B65G15/22—Conveyors having endless load-conveying surfaces, i.e. belts and like continuous members, to which tractive effort is transmitted by means other than endless driving elements of similar configuration comprising a series of co-operating units
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G15/00—Conveyors having endless load-conveying surfaces, i.e. belts and like continuous members, to which tractive effort is transmitted by means other than endless driving elements of similar configuration
- B65G15/30—Belts or like endless load-carriers
-
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
- E04H3/00—Buildings or groups of buildings for public or similar purposes; Institutions, e.g. infirmaries or prisons
- E04H3/08—Hospitals, infirmaries, or the like; Schools; Prisons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Architecture (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Mechanical Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Civil Engineering (AREA)
- Structural Engineering (AREA)
- Physics & Mathematics (AREA)
- Animal Husbandry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a negative pressure transmission pathological examination full-flow system for infectious specimens, which comprises an autopsy chamber, an internal organ specimen sampling chamber, a sampled specimen retention chamber, a pathological technology chamber and a monitoring control chamber, wherein the autopsy chamber, the internal organ specimen sampling chamber and the pathological technology chamber are communicated in a one-way mode through a pipeline system and a transmission channel, and the negative pressure in each chamber is reduced step by step to enable the flow direction of internal gas to flow in a one-way mode; the organ sample sampling chamber is communicated with the sample retention chamber after sampling in a two-way mode through a pipeline system and a transmission channel, the monitoring control chamber is communicated with each chamber through a video conversation system and a remote operation system, and image-text information of pathological examination is uploaded to a pathological data analysis center through a wireless information system; and the autopsy room and the pathological technique room are provided with an air inlet and exhaust and purification system. The negative pressure closed type automatic pipeline mode pathological anatomy material taking system is suitable for pathological examination and application of visceral organs and tissues.
Description
Technical Field
The invention relates to the technical field of specimen examination, in particular to a negative pressure transmission pathology examination full-flow system for an infectious specimen.
Background
The progress of clinical medicine cannot be separated from pathological anatomy; the pathology reveals the nature of the disease, including the etiology, pathogenesis and changes and laws in organs, tissues, cells and even molecules of the body during the course of the disease, and is the basis of the origin and development of modern medicine.
Infectious diseases, such as new coronary pneumonia, are complex diseases with lung diseases mainly involving and affecting multiple organs of the whole body and with a large damage range. Without insights into the etiology and pathological changes, clinical rescue efforts face significant challenges. Through pathological anatomy and subsequent microscopic observation and molecular examination, the distribution of viruses in human bodies and the injury state of organs can be intuitively understood, so that the occurrence mechanism, the propagation path and the target organs of diseases are known, and a key clue is provided for clinical diagnosis and treatment.
At present, a pathological dissection room is simply divided into a polluted area and a clean area, dissectors do not have a safe and effective pathological examination operating platform and related special facilities and equipment, viruses easily diffuse and pollute the personnel and the dissection room through media such as personnel, dissection products, air and the like, and pathological workers are exposed at high risk; meanwhile, at present, the dissection and the material taking of visceral organ specimens are performed manually, and a large amount of time cost and labor cost are consumed for pathological examination, sampling and the like of a large batch of visceral organ and tissue samples; meanwhile, the existing pathological examination lacks a corresponding pipeline design, the processing flow of the specimen or the sample cannot realize that the treatment process has a great exposure risk when the tissue sample with infectivity is anatomically taken and fixed in an isolated and closed environment all the time, and an automatic and intelligent pipeline type pathological adherence treatment device and system are also lacked at present.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides a negative pressure transmission pathological examination full-flow system for infectious specimens, which is a pathological anatomy material taking system in an automatic pipeline mode, has a closed structure with step-by-step negative pressure and is suitable for pathological examination and application of visceral organs and tissues.
In order to achieve the technical purpose and achieve the technical effect, the invention is realized by the following technical scheme:
a negative pressure transmission pathology examination full-flow system for infectious specimens comprises an autopsy chamber, an internal organ specimen sampling chamber, a sampled specimen retention chamber, a pathology technical chamber and a monitoring control chamber, wherein the autopsy chamber, the internal organ specimen sampling chamber and the pathology technical chamber are communicated in a one-way mode through a pipeline system and a transmission channel, and negative pressure in the chambers is reduced step by step to enable internal gas to flow in a one-way mode; the organ sample sampling chamber is communicated with the sample retention chamber after sampling in a two-way mode through a pipeline system and a transmission channel, the monitoring control chamber is communicated with each chamber through a video conversation system and a remote operation system, and image-text information of pathological examination is uploaded to a pathological data analysis center through a wireless information system; and the autopsy room and the pathological technique room are provided with an air inlet and exhaust and purification system.
Furthermore, the organ specimen sampling chamber is of a closed cabinet structure integrally, the inside of the organ specimen sampling chamber is divided into a tissue specimen preprocessing assembly, a tissue specimen sampling assembly, a sample processing assembly and a sample conveying assembly which are mutually communicated, and the operation table tops of the assemblies are positioned on the same plane and are provided with mutually independent conveying belts;
the specimen pretreatment assembly is used for automatic or manual filling of the viscera specimen stationary liquid, specimen code scanning and numbering, and timing or manual/automatic conveying of the specimen;
the sample sampling assembly is used for generally checking and sampling a sample, assisting in processing continuous tissue slices with different thicknesses and batch tissue blocks with different sizes, configuring a required flushing device, a disinfecting device and an audio-video device, and meanwhile, arranging an arm operation hole;
the sample processing assembly is used for fixing and inactivating microorganisms of the taken pathological samples, and the sample conveying assembly is used for conveying inactivated samples without biological safety hazards to a next-stage pathological technical room;
the pathology technical room comprises a tissue dehydrator, a slicer and dyeing machine equipment in the biological safety cabinet structure, image information is wirelessly uploaded to a monitoring control room through slice scanning equipment, and the monitoring control room is arranged and gathered to a pathology information analysis center.
Further, the specimen pretreatment assembly, the specimen sampling assembly, the specimen treatment assembly, the post-sampling specimen retention chamber and the specimen conveying assembly of the visceral organ specimen sampling chamber sequentially comprise a functional part, an operating part and a control part from top to bottom.
Furthermore, the functional part of the specimen pretreatment assembly is provided with a negative pressure device, a fixing liquid filling assembly and a disinfection assembly, the operating part is a conveyor belt for placing a specimen fixing container, and the control part comprises a control button for filling the fixing liquid and the specimen fixing container;
the control buttons comprise an automatic or manual filling button for fixing liquid, an automatic or manual control button for disinfection, and a timing or manual/automatic transfer button for pretreatment of the specimen, and a corresponding indication is arranged above each button.
Furthermore, the functional part of the specimen sampling assembly comprises a disinfection device, a flushing induction device, an audio and video device and a cleaning and containing device for the dissecting instrument, and the operating part comprises a plurality of groups of automatic/semi-automatic auxiliary material taking devices and two arm operating channels;
the flushing induction device and the instrument cleaning and containing device comprise induction elements and execution elements, and the audio and video device is positioned between the induction elements and the execution elements; the automatic/semi-automatic material taking device comprises a parallel tangent plane device, a standard size slicing device and an irregular slicing device.
Furthermore, the functional part of the sample processing assembly comprises an inactivation device, a conveyor belt of the operation part is used for placing a sample for slicing and sampling, and the control part comprises inactivation function selection buttons, time setting buttons and flushing buttons and is provided with a corresponding indicator light;
the inactivation device comprises a liquid filling device and an ultraviolet irradiation device.
Further, the sample conveying assembly conveys the sample through a conveyor belt, and the functional parts of the sample retention chamber after sampling are a fixing liquid filling device and a low-temperature holding device; the sample retention chamber and the visceral organ sample sampling chamber are transmitted by an annular conveyor belt after sampling.
Furthermore, induction opening and closing windows are arranged among the specimen pretreatment assembly, the specimen sampling assembly, the specimen processing assembly, the sampled specimen storage chamber and the sample conveying assembly to realize conduction and sealing, and a passageway is formed between the opening and closing windows at all levels; the logic between the induction opening and closing windows is as follows: when the next-stage transmission is carried out, the induction transmission door of the next stage is preferentially opened, and after the transmission is finished, the induction opening and closing window of the previous stage does not react.
The invention also aims to provide an application of the semi-automatic pathological examination negative pressure system for the infectious specimen in the pathological dissection of the corpse of the human infectious disease.
The invention also aims to provide an application of the semi-automatic negative pressure system for pathological examination of the infectious specimen in pathological anatomy of experimental animals.
The invention has the beneficial effects that:
the automatic treatment system for pathological dissection of infectious diseases comprises an autopsy room, an internal organ sample sampling room, a sampled sample retention room, a pathological technology room and a monitoring control room, wherein the autopsy room, the internal organ sample sampling room, the pathological technology room and the monitoring control room are sequentially communicated through a pipeline system, the sampled sample retention room is connected to the rear side of the internal organ sample sampling room, and the automatic treatment of pathological dissection is carried out through a treatment system with an integrated structure;
the viscera sample sampling chamber is an enclosed cabinet body as a whole, the sample pretreatment assembly, the sample sampling assembly, the sample processing assembly and the sample conveying assembly are conducted through the induction opening and closing window, the operation table tops of the assemblies are positioned on the same plane, and the conveying belts are arranged to convey the processing assemblies and operate independently; the specimen pretreatment assembly is used for automatic or manual filling of fixing liquid, timing or manual/automatic conveying of pretreatment specimens; the sample sampling assembly is used for sampling, washing, disinfecting and shooting a sample, and is also provided with an operation channel for manual sampling operation; the sample treatment assembly is used for carrying out selective inactivation treatment on a sampled product, the sample conveying assembly conveys the sample subjected to inactivation to the next step, pathological anatomy is carried out through autopsy, pathological sample sampling, sample retention and sample treatment by the integrated automatic pathological anatomy system, and pathological anatomy material taking is carried out through closed automatic pipeline mode pathological anatomy material taking and is suitable for pathological anatomy material taking application;
according to the autopsy room, the visceral organ specimen sampling room, the sampled specimen retention room, the pathological technique room and the monitoring control room, relevant operations are carried out through the monitoring control room to obtain relevant image data information of pathological specimens, meanwhile, manual assistance can be matched, the whole system is a pathological anatomy material taking system in an automatic pipeline mode, is in a negative-pressure step-by-step closed structure, and is suitable for pathological examination and application of visceral organs and tissues;
the pathological technical chamber realizes one-way communication through the pipeline system and the transmission channel, negative pressure in each chamber is reduced step by step to enable the flow direction of internal gas to flow in a one-way mode, and the ends of the autopsy chamber and the pathological technical chamber are provided with an air inlet and exhaust and purification system to realize one-way conveying of samples and negative pressure; meanwhile, the design of the air inlet and exhaust system and the purification system can ensure that the gas entering the system and exhausted from the system is harmless, and the safety of pathological anatomy of infectious diseases is also ensured.
Of course, it is not necessary for any product in which the invention is practiced to achieve all of the above-described advantages at the same time.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic structural diagram of an automated infectious disease pathological anatomy treatment system according to an embodiment of the present invention;
FIG. 2 is a schematic structural diagram of an organ specimen sampling chamber according to an embodiment of the present invention;
FIG. 3 is a schematic plan view of an organ specimen sampling chamber according to an embodiment of the present invention;
FIG. 4 is a schematic plan view of the specimen preparation assembly, the specimen sampling assembly, the sample processing assembly and the sample transport assembly according to the embodiment of the present invention;
FIG. 5 is a schematic diagram of the internal structure of the pre-processing assembly, the specimen sampling assembly, the sample processing assembly and the sample delivery assembly according to the embodiment of the present invention;
FIG. 6 is a schematic view of a specimen sampling assembly according to an embodiment of the present invention;
FIG. 7 is a schematic plan view of the specimen retention chamber after sampling in accordance with an embodiment of the present invention;
FIG. 8 is a flowchart of the operation of the automated infectious disease pathological anatomy treatment system according to the embodiment of the present invention;
in the drawings, the components represented by the respective reference numerals are listed below:
1-autopsy room, 2-visceral organ specimen sampling room, 201-closed cabinet, 202-specimen pretreatment component, 2021-negative pressure device, 2022-stationary liquid filling component, 2023-specimen stationary container, 2024-automatic or manual filling button, 2025-timing or manual/automatic transmission button, 203-specimen sampling component, 2031-flushing induction device, 2032-instrument cleaning and containing device, 2033-audio and video device, 2034-operation channel, 2035-automatic/semi-automatic material taking device, 204-specimen processing component, 2041-liquid filling device, 2042-ultraviolet irradiation device, 2043-function selection button, 2044-time setting button, 2045-flushing button, 205-specimen conveying component, 206-conveyor belt, 207-opening and closing window, 208-passage, 3-sample retention chamber after sampling, 301-stationary liquid filling device, 302-low temperature retaining device, 4-pathology technical chamber, and 5-monitoring control chamber.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
As shown in fig. 1-6
A negative pressure transmission pathology examination full-flow system for infectious specimens comprises an autopsy chamber, an internal organ specimen sampling chamber, a sampled specimen retention chamber, a pathology technical chamber and a monitoring control chamber, wherein the autopsy chamber, the internal organ specimen sampling chamber and the pathology technical chamber are communicated in a one-way mode through a pipeline system and a transmission channel, and negative pressure in the chambers is reduced step by step to enable internal gas to flow in a one-way mode; the organ sample sampling chamber is communicated with the sample retention chamber after sampling in a two-way mode through a pipeline system and a transmission channel, the monitoring control chamber is communicated with each chamber through a video conversation system and a remote operation system, and image-text information of pathological examination is uploaded to a pathological data analysis center through a wireless information system; and the autopsy room and the pathological technique room are provided with an air inlet and exhaust and purification system.
A semi-automatic pathological examination negative pressure system for infectious specimens comprises an autopsy chamber 1, an organ specimen sampling chamber 2, a sampled specimen retention chamber 3, a pathological technology chamber 4 and a monitoring control chamber 5, wherein the autopsy chamber 1, the organ specimen sampling chamber 2 and the pathological technology chamber 4 are communicated in a one-way mode through a pipeline system and a transmission channel, negative pressure in each chamber is reduced step by step to enable internal gas to flow in a one-way mode, the organ specimen sampling chamber 2 is communicated with the sampled specimen retention chamber 3 in a two-way mode through the pipeline system and the transmission channel, the monitoring control chamber 5 is communicated with each chamber through a video dialogue system and a remote operation system, and image-text information of pathological examination is uploaded to a pathological data analysis center through a wireless information system; and the autopsy room and the pathological technique room are provided with an air inlet and exhaust and purification system.
The exhaust and purification system meets the national P3 laboratory intake and exhaust standard, and the intake and exhaust system is provided with a purification system
The organ sample sampling chamber 2 is an enclosed cabinet 201 as a whole, the interior of the organ sample sampling chamber is divided into a sample pretreatment assembly 202, a sample sampling assembly 203, a sample processing assembly 204 and a sample conveying assembly 205 which are communicated with each other, the operation table surfaces of the assemblies are positioned on the same plane and are provided with a conveyor belt 206,
the specimen pretreatment assembly 202 is used for automatic or manual filling of organ specimen stationary liquid, specimen code scanning and numbering, and timing or manual/automatic conveying of the specimen;
the specimen sampling assembly 203 is used for generally inspecting and sampling specimens, assisting in processing continuous tissue slices with different thicknesses and batch tissue blocks with different sizes, configuring a required flushing device, a disinfecting device and an audio-video device, and simultaneously arranging an arm operation hole;
the sample processing component 204 is used for fixing and inactivating microorganisms of the taken pathological sample, and the sample conveying component 205 conveys the inactivated biosafety-harmless sample to the next stage of pathology technical room 4;
the pathology technical room 4 comprises a tissue dehydrator, a slicer and a dyeing machine device which are arranged in the biological safety cabinet body structure, image information is wirelessly uploaded to the monitoring control room 5 through a slice scanning device, and the monitoring control room 5 is arranged and gathered to a pathology information analysis center.
The specimen pretreatment assembly 202, the specimen sampling assembly 203, the specimen treatment assembly 204, the sampled specimen retention chamber 3 and the specimen conveying assembly 205 of the organ specimen sampling chamber 2 sequentially comprise a functional part, an operating part and a control part from top to bottom.
The functional part of the specimen pretreatment assembly 202 is provided with a negative pressure device 2021 and a stationary liquid filling assembly 2022, the operation part is a conveyor belt 206 for placing a specimen fixing container 2023, and the control part comprises control buttons for filling the stationary liquid and the specimen fixing container;
the control buttons include an automatic or manual priming button 2024 for fixative, a timing or manual/automatic transfer button 2025 for pre-treatment of specimens, and a corresponding indicator light above each button.
The functional part of the specimen sampling assembly 203 comprises a flushing induction device 2031, an audio and video device 2033 and an instrument cleaning and containing device 2032, and the operating part comprises a plurality of groups of automatic/semi-automatic material taking devices 2035 and two operating channels 2034;
the flushing sensing device 2031 and the instrument cleaning and containing device 2032 comprise a sensing element and an executing element, and the audio and video device 2033 is located between the two; the automatic/semi-automatic material taking device 2035 comprises a parallel section device, a standard size slicing device and an irregular slicing device.
The functional part of the sample processing assembly 204 comprises an inactivation device, a sliced and sampled sample is placed on the conveyor belt 206 of the operation part, the control part comprises an inactivation function selection button 2043, a time setting button 2044 and a flushing button 2045, and corresponding indicator lamps are arranged;
the inactivation device includes a liquid filling device 2041 and an ultraviolet irradiation device 2042.
The sample conveying assembly 205 conveys a sample through a conveyor belt, and the functional parts of the sample retention chamber 3 after sampling are a fixing liquid filling device 301 and a low-temperature holding device 302; the sample retention chamber 3 and the visceral organ sample sampling chamber 2 are transmitted by an annular conveyor belt after sampling.
The sample preprocessing component 202, the sample sampling component 203, the sample processing component 204, the sample after sampling retention chamber 3 and the sample conveying component 205 are mutually provided with induction opening and closing windows to realize conduction and sealing.
The autopsy room 1, the viscera sample sampling room 2, the sample retention room after sampling 3, the pathology technical room 4 and the monitoring control room 5 are mutually independent;
it should be noted that, in this application technical scheme, overall structure includes autopsy room, internal organs sample sampling room, sample back sample retention room, pathology technology room and control the room, autopsy room, internal organs sample sampling room, pathology technology room and control the room and communicate in proper order through pipeline system, internal organs sample sampling room rear side connects sample back sample retention room, the automatic processing of pathological anatomy is carried out through the processing system of integrated structure, negative pressure system parameter is according to the relevant requirement of national regulation, safety facility equipment and waste liquid etc. refer to the relevant standard execution of country, entire system is totally enclosed, each indoor negative pressure state that is in the system, and change step by step, thereby make the inside gas of each indoor portion can not leak outside and cause the pollution, can reach the relevant standard of second grade or tertiary biological safety protection laboratory.
According to the technical scheme, the air purifier further comprises a ventilation system which accords with the national standard, the interior of the ventilation system is relatively in a negative pressure state, the ventilation system is provided with a standard purification system, and a high-efficiency filtering system is arranged, so that air intake and exhaust are both efficiently filtered; meanwhile, relatively proper pressure is ensured; the relative pressure in the space is-30 pa to-40 pa, the air cleanliness is from seven to eight grades of GB 50073 plus 2001 clean plant design Specification, the illumination is uniform and not dazzling, and the illumination is not lower than 500 lx;
example 2
The application of a semi-automatic negative pressure system for pathological examination of infectious specimens in pathological dissection of infectious diseases.
Infectious disease pathological anatomy, because of the existence of specificity, compared with common pathological anatomy or a common pathological anatomy chamber is not suitable for corresponding operation;
the automatic treatment system for pathological dissection of infectious diseases comprises an autopsy room, an internal organ sample sampling room, a sampled sample retention room, a pathological technology room and a monitoring control room, wherein the autopsy room, the internal organ sample sampling room, the pathological technology room and the monitoring control room are sequentially communicated through a pipeline system, the sampled sample retention room is connected to the rear side of the internal organ sample sampling room, and the automatic treatment of pathological dissection is carried out through a treatment system with an integrated structure;
when pathological dissection of infectious diseases is carried out, autopsy is carried out from an autopsy room and is transmitted to an organ specimen sampling room for corresponding operation;
the viscera sample sampling chamber adopts an integrally closed cabinet body, and comprises a sample pretreatment component, a sample sampling component, a sample processing component and a sample conveying component which are communicated through an induction opening and closing window, wherein the operation table tops of the components are positioned on the same plane and are provided with conveyor belts for conveying the processing components, and the conveyor belts run independently;
the specimen pretreatment assembly carries out automatic or manual filling of fixing liquid and timing or manual/automatic transmission of a pretreatment specimen through a designed negative pressure device and a fixing liquid filling device, and the filling of the fixing liquid carries out manual or automatic filling of the fixing liquid on the viscera specimen placed in the specimen fixing container through induction; simultaneously, the pre-processed sample is transmitted to the sample sampling assembly at regular time or by hand/automatic transmission through a corresponding control button;
the functional part of the sample sampling assembly comprises a washing induction device, an audio and video device and an instrument cleaning and accommodating device, and the operating part comprises a plurality of groups of automatic/semi-automatic material taking devices and two operating channels; the device is used for sampling, washing, disinfecting and shooting a specimen, and is also provided with an operation channel for manual sampling operation;
during specific operation, the flushing induction device and the instrument cleaning and containing device are used for flushing and disinfecting viscera and operating instruments, the audio and video device is used for recording the sampling process, and meanwhile, corresponding operation is carried out through a plurality of groups of automatic/semi-automatic material taking devices, each automatic/semi-automatic material taking device comprises a parallel section device, a standard size section device and an irregular section device, and standard or unqualified section operation is carried out on the pathological samples according to the required sizes, the automatic/semi-automatic material taking devices can save physical strength and are convenient to operate, then one part of the sliced pathological samples is transmitted to a sample storage chamber for filling of fixing liquid and low-temperature maintenance, and the other part of the sliced pathological samples is transmitted to the sample processing assembly for carrying out selective inactivation treatment on the sampled samples;
the inactivation device of the sample processing assembly comprises a liquid filling device and an ultraviolet irradiation device, a sliced and sampled sample is placed on a conveyor belt of an operation part, a control part comprises inactivation function selection, time setting and flushing buttons, corresponding indicator lamps are arranged, and corresponding inactivation operation is carried out through the selection function so as to be transmitted to the next stage;
the automatic pathological anatomy system of integral type is from autopsy, pathological specimen sample, sample is preserved and the sample is handled and is carried out pathological anatomy, draws materials through the pathological anatomy of the automatic assembly line mode of closed, is fit for pathological anatomy and draws materials the application.
Example 3
The application of a semi-automatic negative pressure system for pathological examination of infectious specimens in pathological anatomy;
based on the embodiment, the automatic treatment system for infectious disease pathological anatomy can be applied to common pathological anatomy;
the system is designed for an automatic or semi-automatic system, can carry out adaptive treatment on pathological anatomy specimens, and is convenient to operate.
The automatic treatment system for pathological dissection of infectious diseases comprises an autopsy room, an internal organ sample sampling room, a sampled sample retention room, a pathological technology room and a monitoring control room, wherein the autopsy room, the internal organ sample sampling room, the pathological technology room and the monitoring control room are sequentially communicated through a pipeline system, the sampled sample retention room is connected to the rear side of the internal organ sample sampling room, and the automatic treatment of pathological dissection is carried out through a treatment system with an integrated structure;
the viscera sample sampling chamber is an enclosed cabinet body as a whole, the sample pretreatment assembly, the sample sampling assembly, the sample processing assembly and the sample conveying assembly are conducted through the induction opening and closing window, the operation table tops of the assemblies are positioned on the same plane, and the conveying belts are arranged to convey the processing assemblies and operate independently; the specimen pretreatment assembly is used for automatic or manual filling of fixing liquid, timing or manual/automatic conveying of pretreatment specimens; the sample sampling assembly is used for sampling, washing, disinfecting and shooting a sample, and is also provided with an operation channel for manual sampling operation; the sample processing assembly is used for carrying out selective inactivation treatment on the sampled product, the sample conveying assembly conveys the sample subjected to inactivation to the next step, the autopsy system is subjected to autopsy, pathological specimen sampling, specimen preservation and specimen treatment through integral automation to carry out pathological anatomy, and the pathological anatomy in a closed automatic pipeline mode is used for drawing materials and is suitable for pathological anatomy drawing materials.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.
Claims (10)
1. A negative pressure transmission pathology inspection full-process system for infectious specimens is characterized in that: the autopsy room, the visceral organ sample sampling room and the pathological technical room are communicated in a one-way mode through a pipeline system and a transmission channel, and negative pressure in each room is reduced step by step to enable internal gas to flow in a one-way mode; the organ sample sampling chamber is communicated with the sample retention chamber after sampling in a two-way mode through a pipeline system and a transmission channel, the monitoring control chamber is communicated with each chamber through a video conversation system and a remote operation system, and image-text information of pathological examination is uploaded to a pathological data analysis center through a wireless information system; and the autopsy room and the pathological technique room are provided with an air inlet and exhaust and purification system.
2. The negative pressure transport pathology examination full flow system for infectious specimens of claim 1, characterized in that: the visceral organ sample sampling chamber is of a closed cabinet structure integrally, the interior of the visceral organ sample sampling chamber is divided into a tissue sample pretreatment assembly, a tissue sample sampling assembly, a sample processing assembly and a sample conveying assembly which are communicated with each other, and the operation table tops of the assemblies are positioned on the same plane and are provided with mutually independent conveying belts;
the specimen pretreatment assembly is used for automatic or manual filling of the viscera specimen stationary liquid, specimen code scanning and numbering, and timing or manual/automatic conveying of the specimen;
the sample sampling assembly is used for generally checking and sampling a sample, assisting in processing continuous tissue slices with different thicknesses and batch tissue blocks with different sizes, configuring a required flushing device, a disinfecting device and an audio-video device, and meanwhile, arranging an arm operation hole;
the sample processing assembly is used for fixing and inactivating microorganisms of the taken pathological samples, and the sample conveying assembly is used for conveying inactivated samples without biological safety hazards to a next-stage pathological technical room;
the pathology technical room comprises a tissue dehydrator, a slicer and dyeing machine equipment in the biological safety cabinet structure, image information is wirelessly uploaded to a monitoring control room through slice scanning equipment, and the monitoring control room is arranged and gathered to a pathology information analysis center.
3. The negative pressure transport pathology examination full flow system for infectious specimens of claim 2, characterized in that: the specimen pretreatment assembly, the specimen sampling assembly, the sample treatment assembly, the sample storage chamber after sampling and the sample conveying assembly of the visceral organ specimen sampling chamber are sequentially a functional part, an operating part and a control part from top to bottom.
4. The negative pressure transport pathology examination full flow system for infectious specimens of claim 3, characterized in that: the functional part of the specimen pretreatment assembly is provided with a negative pressure device, a fixing liquid filling assembly and a disinfection assembly, the operating part is a conveyor belt for placing a specimen fixing container, and the control part comprises a control button for filling the fixing liquid and the specimen fixing container;
the control buttons comprise an automatic or manual filling button for fixing liquid, an automatic or manual control button for disinfection, and a timing or manual/automatic transfer button for pretreatment of the specimen, and a corresponding indication is arranged above each button.
5. The negative pressure transport pathology examination full flow system for infectious specimens of claim 3, characterized in that: the functional part of the specimen sampling assembly comprises a disinfection device, a flushing induction device, an audio and video device and an dissecting instrument cleaning and accommodating device, and the operating part comprises a plurality of groups of automatic/semi-automatic auxiliary material taking devices and two arm operating channels;
the flushing induction device and the instrument cleaning and containing device comprise induction elements and execution elements, and the audio and video device is positioned between the induction elements and the execution elements; the automatic/semi-automatic material taking device comprises a parallel tangent plane device, a standard size slicing device and an irregular slicing device.
6. The negative pressure transport pathology examination full flow system for infectious specimens of claim 3, characterized in that: the functional part of the sample processing assembly comprises an inactivation device, a conveyor belt of the operation part is used for placing a sample for slicing and sampling, and the control part comprises inactivation function selection buttons, time setting buttons and flushing buttons and is provided with a corresponding indicator light;
the inactivation device comprises a liquid filling device and an ultraviolet irradiation device.
7. The negative pressure transport pathology examination full flow system for infectious specimens of claim 3, characterized in that: the sample conveying assembly conveys a sample through a conveyor belt, and the functional parts of the sample retention chamber after sampling are a fixed liquid filling device and a low-temperature holding device; the sample retention chamber and the visceral organ sample sampling chamber are transmitted by an annular conveyor belt after sampling.
8. The negative pressure transport pathology examination full flow system for infectious specimens of claim 3, characterized in that: sample preliminary treatment subassembly, sample sampling subassembly, sample processing subassembly, sample back sample retention room and sample transport subassembly install the response each other and open and shut the window and realize switching on and sealing, are the passageway between the window that opens and shuts.
9. Use of the semi-automatic negative pressure system for pathological examination of infectious specimens of claim 1 in the autopsy of human infectious diseases.
10. Use of a semi-automatic negative pressure system for pathological examination of infectious specimens as defined in claim 1 in the pathological dissection of experimental animals.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011014353.9A CN112263281A (en) | 2020-09-21 | 2020-09-21 | Negative pressure transmission pathology examination full-flow system for infectious specimen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011014353.9A CN112263281A (en) | 2020-09-21 | 2020-09-21 | Negative pressure transmission pathology examination full-flow system for infectious specimen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112263281A true CN112263281A (en) | 2021-01-26 |
Family
ID=74349225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011014353.9A Pending CN112263281A (en) | 2020-09-21 | 2020-09-21 | Negative pressure transmission pathology examination full-flow system for infectious specimen |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112263281A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116374543A (en) * | 2023-02-27 | 2023-07-04 | 武汉华康世纪医疗股份有限公司 | Medical sample transfer apparatus and method |
| CN113397755B (en) * | 2021-07-20 | 2023-08-25 | 南京吉才汇科技有限公司 | Medical transfer device and method for animal dissecting waste |
-
2020
- 2020-09-21 CN CN202011014353.9A patent/CN112263281A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113397755B (en) * | 2021-07-20 | 2023-08-25 | 南京吉才汇科技有限公司 | Medical transfer device and method for animal dissecting waste |
| CN116374543A (en) * | 2023-02-27 | 2023-07-04 | 武汉华康世纪医疗股份有限公司 | Medical sample transfer apparatus and method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN112263281A (en) | Negative pressure transmission pathology examination full-flow system for infectious specimen | |
| CN209780335U (en) | Biological safety type movable modular negative pressure isolation chamber | |
| CN109661582A (en) | Automatic cytological processing system and method | |
| CN108611271A (en) | Totally enclosed type intelligent biology production system and production method | |
| CN104353095A (en) | Sterility test process isolator | |
| CN105196313A (en) | Sterility test process isolator for double-sided laminar flow operation | |
| CN110982685A (en) | Unmanned isolation detection system and method for high-risk pathogenic microorganisms | |
| CN214318047U (en) | Negative pressure transmission pathology examination full-flow system for infectious specimen | |
| CN115927550A (en) | Full-automatic nucleic acid sample detection pretreatment method | |
| CN102337210B (en) | Positive and negative pressure compatible cell exposure aseptic shielding cabinet equipment | |
| RU180216U1 (en) | MOBILE LABORATORY FOR MONITORING AND DIAGNOSTICS OF PARTICULAR HAZARDOUS INFECTIONS | |
| CN212388022U (en) | Microbial detection incubator | |
| CN205310303U (en) | Sterility testing technology isolator of two -sided laminar flow operation | |
| CN108641953A (en) | Totally enclosed type intelligent biology production system and production method | |
| US10000730B2 (en) | Biomaterial handling device | |
| CN107347687A (en) | One kind operation door flip-up style bio-safety isolating device | |
| CN217389627U (en) | Small-size animal culture apparatus with independent ventilation function | |
| FI106561B (en) | Method and apparatus for enrichment and examination of microbiological samples | |
| CN113801770A (en) | Pretreatment device for nucleic acid detection | |
| CN115820390A (en) | Microbial cultivation device | |
| JP7376716B2 (en) | Inspection equipment system | |
| CN210752732U (en) | A aseptic manipulation device for stem cell preparation | |
| CN212375257U (en) | Superclean bench combined device | |
| CN207159217U (en) | A kind of microbial inoculant specimen cup | |
| CN110411787B (en) | A collection processing apparatus for clinical laboratory's urine sample |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |