CN220473159U - Mixing mechanism, cleaning device and sample analyzer - Google Patents

Abstract

The utility model discloses a mixing mechanism, a cleaning device and a sample analyzer, wherein the mixing mechanism comprises a rotating shaft, a mixing power part and a connecting piece, the rotating shaft is in transmission connection with the mixing power part, the connecting piece is used for connecting a reaction cup, and the rotation center of the rotating shaft and the rotation center of the connected reaction cup are not in the same straight line. The application discloses can avoid liquid in the reaction cup to splash to outside mixing mechanism when mixing, drive the eccentric rotation of reaction cup when mixing, realize quick, the effective shaking of reaction cup inside material, this is non-contact vortex mixing, and liquid in the reaction cup does not produce violent collision, so also is difficult for splashing and causes the pollution.

Description

Mixing mechanism, cleaning device and sample analyzer

Technical Field

The utility model relates to the technical field of sample analyzers, in particular to a mixing mechanism, a cleaning device and a sample analyzer.

Background

Among various sample analyzers, a chemiluminescent immunoassay method is one of the most common technologies, and the technology is an analysis technology combining a chemiluminescent assay technology with a high-specificity antigen-antibody reaction, wherein magnetic bead cleaning and separation are important steps, sample reagent compounds combined with magnetic beads are separated from liquid phases by adopting a magnetic field and used for removing unbound reactants, the aggregated magnetic beads are scattered for many times in the process, and the magnetic beads are scattered in the prior art in a mode of oscillating a reaction cup by adopting linear reciprocating motion, so that liquid in the reaction cup collides back and forth, and even though effective mixing can be realized, the liquid in the reaction cup is easy to splash to form pollution.

Disclosure of Invention

The utility model discloses a mixing mechanism, a cleaning device and a sample analyzer, which are used for solving the problem that liquid in a reaction cup is easy to splash to the outside to cause pollution when mixing is carried out in the prior art.

The utility model provides a mixing mechanism which comprises a rotating shaft, a mixing power part and a connecting piece, wherein the rotating shaft is in transmission connection with the mixing power part, the connecting piece is used for connecting a reaction cup, and the rotation center of the rotating shaft and the rotation center of the connected reaction cup are not in the same straight line.

Optionally, the connecting piece is the columnar structure of coaxial being fixed in the pivot, the free end eccentric seting up of connecting piece is used for holding the recess of reaction cup, the lateral both ends of recess run through connecting piece lateral part, recess width slightly is greater than the reaction cup and corresponds the position external diameter.

Optionally, the connecting piece is the column structure that is fixed in the pivot eccentrically, the recess that is used for holding the reaction cup is seted up at the free end middle part of connecting piece, recess width slightly is greater than the reaction cup and corresponds the position external diameter.

Optionally, the output of the pivot or the blending power portion of blending mechanism is connected with the code wheel that resets, one side of code wheel that resets is provided with the opto-coupler that resets, the recess angle that indicates the connecting piece when the opto-coupler that resets is triggered to reset can supply the reaction cup to pass in and out.

The utility model also provides a cleaning device, which comprises any mixing mechanism, a rotary table and a plurality of cleaning components capable of controlling up-and-down movement, wherein a plurality of cup positions for accommodating reaction cups are circumferentially arranged on the rotary table, the rotary table rotates to drive the reaction cups in each cup position to move and pass through the lower parts of the cleaning components in sequence when in operation, the cleaning components comprise a liquid injection needle and a liquid suction needle, and a magnetic block group for adsorbing magnetic beads in the reaction cups is arranged on the side part of the cup position corresponding to the liquid suction needle.

Optionally, a connecting piece of a mixing mechanism is arranged below at least a part of the liquid injection needle, and the magnetic block group is further arranged on the side part of the cup position corresponding to the liquid injection needle-liquid suction needle interval of each cleaning assembly.

Optionally, the device further comprises a detection mechanism for detecting the luminescence amount of the reaction cup and a filling mechanism, wherein the filling mechanism is used for filling the excitation liquid into the reaction cup, and the filling mechanism and the detection mechanism are arranged behind the last group of cleaning components.

Optionally, a plurality of mixing mechanisms are arranged from the lower part of the filling mechanism to the position between the filling mechanism and the detection mechanism.

Optionally, the rotating shaft and the mixing power part of the mixing mechanism are both connected with synchronous wheels, the synchronous wheels of the mixing mechanism at each cleaning assembly are connected with the synchronous wheels of one mixing power part through synchronous belts, and the synchronous wheels of the mixing mechanism at the filling mechanism are connected with the synchronous wheels of the other mixing power part through synchronous belts.

The utility model also provides a sample analyzer, which comprises any one of the cleaning devices.

The utility model adopts the technical proposal and has the following advantages:

1. the application discloses a can avoid liquid in the reaction cup to splash to outside mixing mechanism when mixing, drive the eccentric rotation of reaction cup when mixing, realize the quick, the effective shaking of reaction cup inside material, this is non-contact vortex mixing, liquid in the reaction cup does not produce violent collision, so also is difficult to splash and cause pollution;

2. the mixing mechanism disclosed by the application does not need to move up and down during operation, and only the reset optocoupler is used for determining whether the angle of the groove meets the requirement of the reaction cup for entering and exiting, so that the mechanical structure of the mixing mechanism is simplified, the mixing can be started more quickly after the position of the reaction cup is switched, and the overall efficiency is improved;

3. the application discloses a belt cleaning device that contains above-mentioned mixing mechanism, mixing mechanism are cooperated annotating liquid needle, imbibition needle, magnetic path group and are effectively realized the washing of reaction cup, and wherein magnetic path group makes the magnetic bead gather and is not taken away by imbibition needle, and mixing mechanism breaks up the magnetic bead and strengthens annotating the cleaning performance of liquid needle, and whole work flow is reasonable and keeps higher detection efficiency;

to sum up: the mixing mechanism disclosed by the application can not only effectively avoid pollution caused by splashing of liquid in the reaction cup during mixing, but also simplify the connection steps of the reaction cup and the reaction cup due to the arrangement of the groove at the upper part of the mixing mechanism, and optimize the transfer speed of the reaction cup; the mixing mechanism can be used for mixing the cleaning liquid while injecting the cleaning liquid, so that the overall detection efficiency is obviously improved.

Drawings

FIG. 1 is a schematic structural view of a mixing mechanism according to the present application;

FIG. 2 is a schematic cross-sectional view of a blending mechanism of the present application;

FIG. 3 is a schematic structural view of the mixing mechanism directly connected with the mixing power part;

FIG. 4 is a schematic view of a cleaning device provided with a mixing mechanism according to the present application;

FIG. 5 is an enlarged schematic view of a portion of a fourth cleaning assembly section magnet block set of the present application;

FIG. 6 is a schematic view of the present application from another perspective of FIG. 4;

fig. 7 is a schematic view showing a state that the cleaning device of the present application includes a detection mechanism.

Reference numerals: the liquid filling device comprises a rotating shaft 1, a connecting piece 2, a groove 3, a motor 4, a reset code disc 5, a reset optocoupler 6, a synchronous wheel 7, a rotary disc 8, a first 911 liquid injection needle, a first 912 liquid suction needle, a second 921 liquid injection needle 922, a second liquid suction needle 931, a third liquid injection needle 932, a fourth 941 liquid injection needle 942, a fourth liquid suction needle 942, a group of 10 magnetic blocks, a cup ejection mechanism 11, a detection mechanism 12, a cup outlet 13, a cup inlet 14, a liquid injection plate 15, a liquid suction plate 16 and a filling mechanism 17.

Detailed Description

The following description of the embodiments of the present application will be made clearly and fully, and it is apparent that the embodiments described are only some, but not all, of the embodiments of the present application. All other embodiments, which can be made by those skilled in the art without the exercise of inventive faculty, are intended to be within the scope of the utility model.

Please refer to fig. 1, a mixing mechanism, including pivot 1, mixing power portion and connecting piece 2, pivot 1 is connected with mixing power portion transmission for pivot 1 receives mixing power portion drive and produces and rotate, and connecting piece 2 is used for connecting the reaction cup, and the rotation center of pivot 1 and the rotation center of reaction cup are not in same straight line, thereby make mixing power portion drive the eccentric rotation of reaction cup at the during operation, realize quick, the effective shaking of reaction cup inside material, because for non-contact vortex mixing in this scheme, liquid in the reaction cup does not produce violent collision, so also be difficult for splashing and cause the pollution.

The connecting piece 2 can be in various specific structures, such as a clamping jaw for directly clamping the outer wall of the reaction cup, a supporting plate extending into the opening of the reaction cup from the upper part and propping against the side wall of the reaction cup, and the like, and a person skilled in the art can select a proper connecting piece 2 according to the actual operation environment, and simultaneously, the reaction cup can eccentrically rotate under the action of the connecting piece 2;

referring to fig. 2, in this embodiment, the connecting piece 2 is of a columnar structure coaxially fixed on the rotating shaft 1, the free end of the connecting piece 2 is eccentrically provided with a groove 3 for accommodating a reaction cup, the width of the groove 3 is slightly larger than the outer diameter of the corresponding position of the reaction cup, the reaction cup can enter along the opening direction of the side part of the groove 3, then the mixing power part drives the rotating shaft 1 to rotate, the side wall of the groove 3 pushes the reaction cup to rotate, and the groove 3 of the connecting piece 2 is eccentrically arranged, so that the reaction cup is driven to eccentrically rotate when the connecting piece 2 rotates, and the mixing of substances inside the reaction cup is realized.

In another embodiment, the connecting piece 2 can also be arranged to be eccentrically fixed on the columnar structure of the rotating shaft 1, the middle part of the free end of the connecting piece 2 is provided with a groove 3 for accommodating the reaction cup, the width of the groove 3 is slightly larger than the outer diameter of the corresponding position of the reaction cup, the mixing power part drives the rotating shaft 1 to rotate after the reaction cup enters the groove 3, and the connecting piece 2 body can eccentrically rotate to drive the reaction cup positioned in the middle part of the connecting piece 2 to eccentrically rotate so as to realize the mixing of substances in the reaction cup.

The output end of the rotating shaft 1 or the mixing power part of the mixing mechanism is connected with a reset code disc 5, one side of the reset code disc 5 is provided with a reset optocoupler 6, when the reset code disc 5 triggers the reset optocoupler 6, the angle of the groove 3 of the indication connecting piece 2 can be used for a reaction cup to enter and exit, the reaction cup can be driven by the outside to enter and exit the groove 3 of the mixing mechanism from the horizontal direction, and the reset optocoupler 6 and the reset code disc 5 are used for determining the angle of the groove 3, so that the condition that the reaction cup is damaged due to the angle error is avoided.

Referring to fig. 3, the mixing power portion in this embodiment is a motor 4, and an output end of the motor 4 is fixedly connected with the rotating shaft 1 coaxially, the reset code wheel 5 is connected with an output shaft of the motor 4, and the reset optocoupler 6 is connected to an outer wall of the motor 4, which is an embodiment in which the rotating shaft 1 is directly connected with the mixing power portion.

The application also discloses a cleaning device which comprises any mixing mechanism, a rotary table 8 and a plurality of cleaning components which are controlled to move up and down, wherein a plurality of cup positions for accommodating reaction cups are circumferentially distributed on the rotary table 8; each cleaning component is sequentially distributed along the periphery of the turntable 8, and comprises a liquid injection needle and a liquid suction needle; the mixing mechanism is arranged below the corresponding reaction cup position of all or part of the liquid injection needles; the rotary table 8 rotates to drive the reaction cups in each cup position to move and pass through the lower parts of the cleaning assemblies in sequence, the liquid injection needle fills the cleaning liquid into the reaction cups to clean the magnetic beads in the reaction cups, then the reaction cups move to the lower parts of the liquid suction needles, the liquid suction needles move downwards into the reaction cups to suck the cleaned waste liquid, and the reaction cups are cleaned once; the mixing mechanism shakes the reaction cup injected with the cleaning liquid uniformly, so that the magnetic beads are fully contacted with the cleaning liquid.

In order to avoid the loss of the magnetic beads along with the waste liquid discharge when the liquid suction needle sucks liquid, the side part of the cup position corresponding to the liquid suction needle is provided with a magnetic block group 10 for adsorbing the magnetic beads in the reaction cup, and the side part of the cup position corresponding to the mixing mechanism can also be provided with the magnetic block group 10, and the main reason is that: the mixing mechanism has a strong mixing and scattering effect on the magnetic beads, the magnetic field generated by the magnetic block group cannot effectively gather the magnetic beads when the mixing mechanism works, the single working time of the mixing mechanism is short, the magnetic field generated by the magnetic block group can start to generate an adsorption gathering effect on the magnetic beads after the mixing mechanism stops working, namely, the magnetic beads start to generate adsorption gathering at the position of the mixing mechanism, so that the magnetic beads are enabled to be longer in magnetic field action time, the magnetic beads have enough time to finish gathering, and the magnetic beads cannot be sucked together with waste liquid when a liquid suction needle works.

The uniform mixing mechanism works to make the reaction cup eccentrically rotate to scatter the magnetic beads gathered by the magnetic force of the magnetic block group 10, so that the cleaning liquid can better contact with the magnetic beads to form a better cleaning effect; the magnetic block group 10 is also arranged at the side part of the cup position corresponding to the interval from the liquid injection needle to the liquid suction needle of each cleaning component, the magnetic block group 10 has the main function of adsorbing the magnetic beads in the aggregation reaction cup, and the magnetic beads are in discrete states in the reaction cup when the cleaning liquid is injected and uniformly mixed, and the magnetic block groups 10 are arranged between the liquid injection needle and the liquid suction needle to enable the interval from the liquid injection needle to have enough time to attract the magnetic beads, so that the magnetic beads are more thoroughly aggregated together.

Additional description is: the reaction cup card is located the cup position of carousel 8, and the cup position of this embodiment sets up to the circular through-hole that the diameter is greater than the reaction cup diameter, and the reaction cup outer wall is provided with the protruding portion, and the protruding portion supports in the upper wall of carousel for the reaction cup can't follow the cup position landing. When the mixing mechanism works, the reaction cup is driven to eccentrically rotate, and as the reaction cup is limited by the outline of the inner ring of the cup position, if the mixing mechanism is not positioned at the right center below the cup position, the outline of the inner ring of the cup position also gives a reaction force to the reaction cup, so that the reaction cup reciprocates along the groove 3, the movement complexity of the reaction cup is increased, and the mixing effect is improved; therefore, in the technical scheme of the application, the setting precision of the reset optocoupler 6 and the reset code disc 5 is not required to be too precise, and the mixing mechanism only needs to work to drive the reaction cup to rotate, so that the reaction cup is not damaged, and a good mixing effect can be generated; meanwhile, the production cost is reduced as higher precision is not needed.

4-6, four groups of cleaning components are arranged (from the cup inlet 14, the four groups of cleaning components are arranged clockwise in sequence, in the drawing, the serial numbers of the first cleaning component are respectively provided with a first liquid injection needle 911 and a first liquid suction needle 912, the second cleaning component is respectively provided with a second liquid injection needle 921 and a second liquid suction needle 922, the third cleaning component is respectively provided with a third liquid injection needle 931 and a third liquid suction needle 932, the fourth cleaning component is respectively provided with a fourth liquid injection needle 941 and a fourth liquid suction needle 942), the reaction cup enters the cleaning device of the embodiment through the cup inlet 14 and is cleaned in a fourth order, and the rotary table 8 drives the reaction cup to rotate clockwise, wherein the mixing mechanism is arranged below the positions of the second, third and fourth liquid injection needles 921, 931 and 941, and the mixing mechanism is not arranged below the position of the first liquid injection needle 911, and the reason is that: the magnetic block group 10 is not arranged between the cup inlet 14 and the first liquid injection needle 911, namely, the magnetic beads in the reaction cup are not gathered and are naturally in a discrete state, and a uniform mixing mechanism is not needed to break up the magnetic beads. In fact, if the mixing mechanism is arranged, the effect of scattering the magnetic beads is not generated, but the stirring effect on the magnetic beads and the cleaning liquid is still generated, so that the mixing effect is enhanced to a certain extent; however, considering that three subsequent cleaning steps still exist in the embodiment, the magnetic beads can be cleaned, so that the meaning of arranging the mixing mechanism is not great.

The magnetic block group 10 is also arranged at the side part of the cup position corresponding to the interval from the liquid injection needle to the liquid suction needle of each cleaning component, so that the magnetic block group has enough time to attract magnetic beads, and the magnetic beads are more thoroughly gathered together.

Referring to fig. 7, the cleaning device further includes a detecting mechanism 12 for detecting the luminescence amount of the reaction cup and a filling mechanism 17, wherein the filling mechanism 17 adds the excitation liquid into the reaction cup, and the filling mechanism 17 and the detecting mechanism 12 are arranged after the last group of cleaning components, namely, after the reaction cup enters the cleaning device, the reaction cup is firstly cleaned by each cleaning component and then is filled with the excitation liquid to detect the luminescence amount; a plurality of mixing mechanisms are arranged between the lower part of the filling mechanism 17 and the position between the filling mechanism and the detecting mechanism 12, and the mixing mechanism aims at mixing the filled excitation liquid and the magnetic beads so as to make the reaction more complete.

Referring to fig. 7, in this embodiment, four liquid injection needles are connected with a liquid injection plate 15, four liquid suction needles are connected with a liquid suction plate 16, the liquid injection plate 15 is located at the lower part of the liquid suction plate 16, and a abdication hole for the liquid suction needle to pass through is formed on the liquid injection plate 15; when the liquid is injected, the liquid injection plate 15 is controlled to move downwards to drive the four liquid injection needles to move downwards synchronously for liquid injection, and when the liquid is absorbed, the liquid absorption plate 16 is controlled to move downwards to drive the four liquid absorption needles to move downwards synchronously for liquid absorption, and the liquid injection plate 15 and the liquid absorption plate 16 are controlled by the lifting device at the side part to realize up-and-down movement, which is a conventional technical means and is not described in detail herein.

The rotating shaft 1 and the mixing power parts of the mixing mechanism are connected with synchronous wheels 7, the synchronous wheels 7 of the mixing mechanism at each cleaning assembly are connected with the synchronous wheels 7 of one mixing power part through synchronous belts, and the synchronous wheels 7 of the mixing mechanism at the filling mechanism 17 are connected with the synchronous wheels 7 of the other mixing power part through synchronous belts; namely, the mixing mechanism at the cleaning assembly works stably and synchronously, and each mixing mechanism at the filling mechanism 17 works stably and synchronously.

The arrangement mode of each magnetic block group 10 is halbach array or multipolar magnetic circuit or magnetism gathering structure, the magnetic block group 10 is formed by combining one or more magnetic units, a single magnetic block group 10 corresponds to one cup position of the reaction cup, the magnetic field intensity of one side of the reaction cup is obviously increased by the arrangement mode of the magnetic block groups 10, the adsorption speed of the magnetic block groups on the magnetic beads is faster, the adsorption force is stronger, and the loss of the magnetic beads along with the washing waste liquid is avoided to a greater extent; the halbach array or the multipolar magnetic circuit or the magnetism collecting structure is a magnet arrangement mode which enables a magnetic field to be obviously enhanced at a certain position, wherein the halbach array is formed by splicing magnetic poles arranged in a rotating way through the angle of the magnetic field, so that a single-sided high-strength magnetic field is formed; the multipolar magnetic circuit is formed by magnetizing one magnet in multiple stages or absorbing a plurality of magnet monopole magnets, so that a magnetic field is gathered on the surface of the magnet; the magnetic focusing structure is formed by arranging magnets and iron yokes according to polarity opposition to realize magnetic field focusing; the selection and arrangement modes of the magnetic block groups 10 are all used for enabling the magnetic field intensity at the reaction cup to be larger and enabling the magnetic beads to be adsorbed more strongly; in addition, the purpose of increasing the magnetic field strength can be realized by selecting a single-sided magnet as a magnetic block group and the like; the magnet blocks 10 are disposed on the outer and/or inner peripheral sides of the corresponding cup positions, and referring to fig. 6, the magnet blocks 10 are disposed on both the inner and outer peripheral sides in this embodiment, so as to ensure that there is sufficient magnetic field strength at the reaction cup.

Referring to fig. 4, at least one cleaning assembly section is gradually lowered in height in the running direction of the reaction cup corresponding to the magnetic block group 10, and the height of the magnetic block group 10 is gradually lowered to gradually lower the aggregation position of the magnetic field, so that the magnetic beads positioned at the high position of the reaction cup are aggregated downwards to a low position, namely more magnetic beads are aggregated into a group instead of being only aggregated into a small group originally and distributed at all positions of the reaction cup; the probability of sucking the magnetic beads by the liquid sucking needle is further reduced by aggregation, and the magnetic beads are positioned at lower points so as to be in complete contact with the cleaning liquid to realize cleaning.

In particular, the height of the magnetic block set 10 in the fourth cleaning assembly section (i.e. the section from the fourth liquid injection needle 941 to the fourth liquid suction needle 942) is gradually reduced, and the magnetic beads located at the high position of the reaction cup are also gathered downwards to a low position, but the cleaning liquid is not injected into the reaction cup later, but the excitation liquid is injected into the reaction cup to perform the luminescence reaction, so that the magnetic beads can react with the excitation liquid more thoroughly, and the sufficient luminescence amount and the accurate measurement result are ensured.

The following describes in detail the circulation process of a cuvette in the cleaning device according to the present application with reference to fig. 4-7: firstly, a reaction cup enters a cleaning device through a cup inlet 14 under the action of an external clamp and is placed on a rotary table 8, the rotary table 8 moves to drive the reaction cup to move to the lower part of a first liquid injection needle 911, the first liquid injection needle 911 injects cleaning liquid into the reaction cup, and at the moment, magnetic beads in the reaction cup are not aggregated, so that the magnetic beads can be well washed and cleaned by the cleaning liquid; the magnetic block group 10 is arranged from the rear of the first liquid injection needle 911 to the position corresponding to the first liquid suction needle 912, namely, the rotary disk 8 rotates to pass through the lower part of the first liquid injection needle 911 and then is acted by the magnetic block group 10, the magnetic beads in the reaction cup start to gather, until the rotary disk 8 makes the reaction cup move to the lower part of the first liquid suction needle 912, the magnetic beads are completely adsorbed and gather, and the first liquid suction needle 912 pumps out the cleaning liquid in the reaction cup; then the rotary table 8 drives the reaction cup to move to the lower part of the second liquid injection needle 921, and when the second liquid injection needle 921 injects cleaning liquid into the reaction cup, the uniformly mixing mechanism at the lower part of the second liquid injection needle works to drive the reaction cup to eccentrically rotate so as to scatter magnetic beads gathered in the reaction cup, and the cleaning liquid and the magnetic beads are well mixed so as to realize cleaning; the operations of the fourth filling needle 941 are repeated completely and will not be described again; after the fourth filling needle 941 is filled with cleaning liquid, the height of the magnetic block group 10 is gradually reduced, so that the magnetic beads are gathered and adsorbed to the lower part of the reaction cup; until the reaction cup moves to the fourth liquid suction needle 942 to suck the cleaning liquid, the reaction cup continues to move to the lower part of the filling mechanism 17 and then is filled with the excitation liquid, a mixing mechanism is arranged at the lower part of the reaction cup, and the mixing mechanism works to break up the aggregated magnetic beads so as to enable the aggregated magnetic beads to fully react with the excitation liquid; when the reaction cup continues to move to the lower part of the measuring chamber 12, the cup jacking mechanism 11 works to jack up the reaction cup to the inside of the detecting mechanism 12, so that the detecting mechanism 12 can effectively detect the luminous quantity of the reaction cup. After the measurement is completed, the cup ejection mechanism 11 works reversely to reset the reaction cup, and when the reaction cup continues to move to the cup outlet 13 along with the turntable 8, the reaction cup is clamped out by the external clamp, so that the whole working flow of the reaction cup in the cleaning device of the embodiment is completed.

The cleaning device of this embodiment further includes a mixing portion for shaking the reaction cup filled with the excitation liquid, where the mixing portion may be the above mixing mechanism or other existing components capable of achieving mixing.

In the above embodiment, the rotating shaft 1 and the mixing power part of each mixing mechanism are connected with the synchronous wheel 7, each synchronous wheel 7 is commonly connected with the synchronous belt, the mixing power part is generally all selected to use the motor 4, the motor 4 drives the synchronous wheel 7 directly connected with the motor to rotate during working, then the synchronous belt drives the step wheel 7 of the rotating shaft 1 to rotate, and further drives each rotating shaft 1 to synchronously rotate, and the rotation angle of each rotating shaft 1 is the same, namely, when the groove 3 of the connecting piece 2 at one rotating shaft 1 is in a state of being capable of entering and exiting the reaction cup, the connecting piece 2 of the rotating shaft 1 connected by the synchronous belt can also enter and exit the reaction cup, so that effective synchronization is realized, sustainable and effective working of the cleaning device is ensured, namely, sustainable cleaning and luminous detection of each reaction cup on the turntable 8 are carried out.

Specifically described are: the application should also set up a plurality of take-up pulleys that are used for making the hold-in range keep tensioning state, generally realize through spring, support promotion connection in the take-up pulley of hold-in range, and this is common sense, and is not repeated here.

The application also provides a sample analyzer, including the belt cleaning device that above-mentioned shows, belt cleaning device washs the reaction cup, luminous detection, and whole work flow is smooth and easy and high-efficient, can accomplish the chemiluminescence detection of sample that awaits measuring fast, in batches.

The foregoing is illustrative of the present utility model and is not to be construed as limiting thereof, but rather as providing for the use of additional embodiments and advantages of all such modifications, equivalents, improvements and similar to the present utility model are intended to be included within the scope of the present utility model as defined by the appended claims.

Claims (10)

1. The utility model provides a mixing mechanism which characterized in that, includes pivot, mixing power portion and connecting piece, the pivot is connected with mixing power portion transmission, the connecting piece is used for connecting the reaction cup, the rotation center of pivot and the rotation center of the reaction cup who connects are not in same straight line.

2. The mixing mechanism according to claim 1, wherein the connecting piece is a columnar structure coaxially fixed on the rotating shaft, the free end of the connecting piece is eccentrically provided with a groove for accommodating the reaction cup, the two transverse ends of the groove penetrate through the side part of the connecting piece, and the width of the groove is slightly larger than the outer diameter of the corresponding position of the reaction cup.

3. The mixing mechanism according to claim 1, wherein the connecting piece is of a columnar structure eccentrically fixed on the rotating shaft, a groove for accommodating the reaction cup is formed in the middle of the free end of the connecting piece, two transverse ends of the groove penetrate through the side part of the connecting piece, and the width of the groove is slightly larger than the outer diameter of the corresponding position of the reaction cup.

4. The mixing mechanism according to claim 1, wherein the output end of the rotating shaft or the mixing power part of the mixing mechanism is connected with a reset code disc, one side of the reset code disc is provided with a reset optocoupler, and the reset code disc triggers the reset optocoupler to indicate the groove angle of the connecting piece to allow the reaction cup to go in and out.

5. The cleaning device is characterized by comprising the mixing mechanism, the rotary table and a plurality of cleaning components capable of controlling up-and-down movement, wherein a plurality of cup positions for accommodating reaction cups are circumferentially distributed on the rotary table, the rotary table rotates to drive the reaction cups in the cup positions to move and sequentially pass through the lower parts of the cleaning components when in operation, the cleaning components comprise liquid injection needles and liquid suction needles, and magnetic block groups for adsorbing magnetic beads in the reaction cups are arranged on the side parts of the cup positions corresponding to the liquid suction needles.

6. The cleaning device according to claim 5, wherein a connecting piece of the mixing mechanism is arranged below at least a part of the liquid injection needles, and the magnetic block group is further arranged on the side part of the cup position corresponding to the liquid injection needle-liquid suction needle interval of each cleaning assembly.

7. The cleaning apparatus according to claim 5, further comprising a detecting means for detecting the amount of luminescence of the cuvette, and a filling means for filling the excitation liquid into the cuvette.

8. The cleaning apparatus according to claim 7, further comprising a mixing section for shaking the cuvette filled with the excitation liquid.

9. The cleaning device according to claim 7, wherein the rotating shaft and the mixing power parts of the mixing mechanism are connected with synchronous wheels, the synchronous wheels of the mixing mechanism at each cleaning assembly are connected with the synchronous wheels of one mixing power part through synchronous belts, and the synchronous wheels of the mixing mechanism at the filling mechanism are connected with the synchronous wheels of the other mixing power part through synchronous belts.

10. A sample analyzer comprising a cleaning device according to any one of claims 5 to 9.