CN218995403U - TIP head box automatic loading and unloading module for chemiluminescence immunity analyzer - Google Patents

TIP head box automatic loading and unloading module for chemiluminescence immunity analyzer Download PDF

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CN218995403U
CN218995403U CN202223250651.5U CN202223250651U CN218995403U CN 218995403 U CN218995403 U CN 218995403U CN 202223250651 U CN202223250651 U CN 202223250651U CN 218995403 U CN218995403 U CN 218995403U
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area
loading
transfer
tip head
tip
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张宁
余农
王永东
胡亮
邱胜
潘伟男
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Kelaisi Biotechnology Chongqing Co ltd
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Kelaisi Biotechnology Chongqing Co ltd
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Abstract

The utility model discloses an automatic loading and unloading module of a TIP head box for a chemiluminescent immunoassay analyzer, which comprises the following components: the base platform is provided with a loading area and a recovery area; the conveying platform is used for conveying the TIP head box, a limiting part is movably arranged at a position, close to the tail end of the conveying platform, the limiting part divides the conveying platform into a waiting area and a transfer area, and the limiting part can be opened so that the TIP head box in the waiting area can enter the transfer area; the transfer mechanism is arranged on the basic platform through a linear module, and the linear module is used for driving the transfer mechanism to reciprocate between the transfer area and the loading area so as to transfer the TIP head box of the transfer area to the loading area; and the unloading mechanism is arranged in the loading area and is used for pushing the TIP head box in the loading area to the recovery area. The beneficial effects of the utility model are as follows: the TIP head box can be installed on line without stopping.

Description

TIP head box automatic loading and unloading module for chemiluminescence immunity analyzer
Technical Field
The utility model relates to a chemiluminescent immunoassay analyzer, in particular to an automatic loading and unloading module of a TIP head box for the chemiluminescent immunoassay analyzer.
Background
The whole process of executing sample detection by the chemiluminescent immunoassay analyzer relates to the transfer of liquid such as sample, reagent and the like. The TIP head is a consumable component for transferring liquid, and needs to be matched with a liquid transfer device in a chemiluminescent immunoassay analyzer, and the liquid transfer process is as follows: the linear module of the analyzer drives the liquid dispenser to move to the position of the TIP head, then the gun head of the liquid dispenser stretches into the TIP head to finish loading of the TIP head, then the TIP head is used for carrying out liquid transfer, and finally the TIP head is thrown into a waste barrel.
In the detection process, a new TIP head needs to be used for each pipetting, so that the consumption of the TIP head is large. In the prior art, TIP heads are loaded into a chemiluminescent immunoassay analyzer by TIP head cartridges, each of which is placed on a number of TIP heads. Currently, with the large-scale increase of detection demands, full-automatic chemiluminescence immunoassay analyzers with higher detection efficiency are actively being introduced in the market. In this case, the loading capability of the TIP head cartridge is also put higher demands on the apparatus.
Disclosure of Invention
In view of the above, the present utility model provides an automatic TIP cassette loading and unloading module for a chemiluminescent immunoassay analyzer, which can realize online installation of TIP cassettes without stopping.
In order to achieve the above purpose, the technical scheme of the utility model is as follows:
a TIP head box automatic handling module for chemiluminescence immunity analyzer, its key lies in: comprising the following steps:
the base platform is provided with a loading area and a recovery area;
the conveying platform is used for conveying the TIP head box, a limiting part is movably arranged at a position, close to the tail end of the conveying platform, the limiting part divides the conveying platform into a waiting area and a transfer area, and the limiting part can be opened so that the TIP head box in the waiting area can enter the transfer area;
the transfer mechanism is arranged on the basic platform through a linear module, and the linear module is used for driving the transfer mechanism to reciprocate between the transfer area and the loading area so as to transfer the TIP head box of the transfer area to the loading area; and
and the unloading mechanism is arranged in the loading area and is used for pushing the TIP head box in the loading area to the recovery area.
Preferably, one end of the limiting component is rotatably connected to one side of the conveying platform, and the other end of the limiting component can be suspended above the conveying platform under the action of gravity;
the limiting component is provided with a protruding part, and the transferring mechanism can push the limiting component to rotate upwards through the protruding part in the process that the transferring mechanism enters the transferring area.
Preferably, a left baffle and a right baffle are respectively arranged on two sides of the conveying platform, and avoidance notches are formed on the left baffle and the right baffle at positions corresponding to the transfer areas; the conveying direction of the conveying platform is perpendicular to the moving direction of the transferring mechanism, and the transferring mechanism can enter and exit the transferring area through the avoidance notch.
Preferably, the transfer mechanism comprises a base, a left retention plate and a right fixing plate extending forwards are respectively arranged at two ends of the base, a clamping piece is movably arranged on the inner side of the right fixing plate, an elastic element is arranged between the clamping piece and the right fixing plate, and force enabling the clamping piece to move towards the direction close to the left retention plate is applied to the elastic element.
Preferably, the rear end of the right baffle is provided with a limiting part, and the limiting part can force the distance between the clamping piece and the left retention plate to be enlarged in the process that the transfer mechanism enters the transfer area.
Preferably, the unloading mechanism comprises a motor and a push rod driven by the motor to move, the push rod is positioned above the loading area, and the push rod can move towards the rear end of the loading area under the driving action of the motor.
Preferably, the motor is fixedly arranged below the loading area, a swing arm is fixedly sleeved on an output shaft of the motor, the loading area is provided with an avoidance opening, the upper end of the swing arm is exposed above the loading area through the avoidance opening, and the push rod is fixedly connected to the upper end of the swing arm.
Preferably, a horizontal support plate is arranged below the loading area, a longitudinal support plate is fixedly arranged on the horizontal support plate, a motor is fixedly assembled on the horizontal support plate, a limit deflector rod is rotatably assembled on the longitudinal support plate, a tension spring is connected between the limit deflector rod and the longitudinal support plate, the tension spring can pull the limit deflector rod to rotate forwards, a driving part is fixedly arranged on the swing arm, and in the process of backward rotation of the swing arm, the driving part can force the limit deflector rod to rotate backwards against the resistance of the tension spring.
Preferably, the base platform is provided with guide wheels at a position close to the transfer area.
Preferably, the conveying platform is a belt conveying mechanism, and the belt conveying mechanism is arranged on the basic platform in a sliding mode in a drawer mode.
Compared with the prior art, the utility model has the beneficial effects that:
1. after the TIP head boxes in a plurality of quantity are preloaded in the waiting area, under the synergistic effect of the conveying platform, the transferring mechanism and the limiting component, the TIP head boxes in the waiting area can be automatically transferred to the loading area one by one, and the high detection efficiency and the high automation process of the chemiluminescent immunoassay analyzer are guaranteed.
2. In the automatic replacement process of the TIP head box 8, the on-line replacement can be realized without stopping the machine, the chemiluminescent immunoassay analyzer is ensured to be capable of realizing long-time operation without stopping the machine, and the machine meets the market demand of large-scale detection.
Drawings
FIG. 1 is a schematic diagram of an automated TIP head cartridge loading and unloading module;
FIG. 2 is a partial schematic view of the rear half of the TIP head cartridge robotic handling module of FIG. 1;
fig. 3 is a sectional view of the transfer mechanism 4;
fig. 4 and 5 are schematic views of the unloading mechanism 6 at different angles;
fig. 6 is a schematic view of the structure of the TIP head cartridge automatic loading and unloading module loaded with the TIP head cartridge 8;
fig. 7 is a schematic structural diagram of fig. 6 at another view angle.
Fig. 8 is a partial enlarged view of i in fig. 7.
Detailed Description
The utility model is further described below with reference to examples and figures.
The description of the orientations "front, rear, left, right" in the following embodiments is referred to with coordinates shown in fig. 1.
As shown in fig. 1 and 2, an automatic TIP cassette loading and unloading module for a chemiluminescent immunoassay analyzer comprises a base platform 1, a transfer platform 2, a limiting member 3, a transfer mechanism 4, an unloading mechanism 6 and other main components. Wherein, the basic platform 1 is in a fixed state in the chemiluminescent immunoassay analyzer, the basic platform 1 is provided with a loading area 1a and a recycling area 1b, in this embodiment, the loading area 1a is a horizontal supporting surface, and the recycling area 1b is provided with a recycling hopper a.
The conveying platform 2 is a belt conveying mechanism and is used for conveying the TIP head box, a limiting part 3 is movably arranged at the position, close to the tail end of the conveying platform 2, and the limiting part 3 divides the conveying platform 2 into a waiting area 2b and a transferring area 2a. The limiting member 3 can be opened by an external force so that the TIP head cartridge of the waiting area 2b can enter the transit area 2a.
The transfer mechanism 4 is mounted on the base platform 1 by means of a linear module 5, in this embodiment the direction of movement of the linear module 5 is perpendicular to the direction of transport of the transport platform 2. The transfer mechanism 4 can reciprocate between the transfer area 2a and the loading area 1a under the drive of the linear module 5. An unloading mechanism 6 is arranged in the loading area 1a and functions to push the TIP head cartridge of the loading area 1a into the recovery hopper a of the recovery area 1b.
Based on the implementation structure, the working principle of the TIP head box automatic loading and unloading module is as follows:
referring to fig. 1 and 6, a user places a plurality of TIP head cartridges 8 on the transfer platform 2, and the TIP head cartridges 8 are orderly arranged in the waiting area 2b under the action of a transfer belt. The linear module 5 then drives the transfer mechanism 4 to move to the transfer zone 2a, in which process the left end of the transfer mechanism 4 touches and pushes away the stop member 3, so that one TIP head cartridge 8 of the waiting zone 2b enters the transfer zone 2a. The linear module 5 then drives the transfer mechanism 4 from the staging area 2a to the loading area 1a, which carries the TIP cassette 8 of the staging area 2a to the loading area 1a. Then, the TIPs on the TIP head cartridges 8 can be loaded at this position by the pipette inside the chemiluminescent immunoassay analyzer, and after the TIPs on the TIP head cartridges 8 are used up, the unloading mechanism 6 pushes the TIP head cartridges in the loading area 1a into the recovery hopper a.
By repeating the above process, the chemiluminescent immunoassay analyzer can automatically replace a new TIP head box 8, and the replacement process analyzer does not need to be stopped, so that the high detection efficiency and the high automation process of the analyzer are ensured. Further, the conveying platform 2 is slidably installed on the base platform 1 back and forth in a drawer mode, when the TIP head boxes 8 in the waiting area 2b consume a certain amount, the conveying platform 2 can be pulled out forward, then the TIP head boxes 8 are supplemented, after the TIP heads on the TIP head boxes 8 in the loading area 1a are used up, the TIP head boxes 8 can be taken out from the conveying platform 2 through the transfer mechanism 4, so that the chemiluminescent immunoassay analyzer is guaranteed to realize long-time non-stop operation, and the large-scale detection requirement of the market is met.
Referring to fig. 2, two sides of the conveying platform 2 are respectively provided with a left baffle plate 2d and a right baffle plate 2e, the left baffle plate 2d and the right baffle plate 2e are provided with an avoidance gap 2c at a position corresponding to the transfer area 2a, and the transfer mechanism 4 enters and exits the transfer area 2a through the avoidance gap 2 c. As can be seen from fig. 7 and 8, the limiting member 3 of this embodiment is of a rocker arm structure, one end of the limiting member is rotatably connected to the outer side of the conveying platform 2, and under the action of the dead weight of the limiting member 3, the other end of the limiting member 3 is suspended above the conveying platform 2, so that the conveying platform 2 is divided into a waiting area 2b and a transferring area 2a. The limiting component 3 is provided with the protruding part 3a, when the transfer mechanism 4 approaches to enter the transfer area 2a completely, the transfer mechanism 4 touches the protruding part 3a and pushes the limiting component 3 to rotate upwards, so that the waiting area 2b and the transfer area 2a are switched into a communicating state, and the TIP head box 8 on the waiting area 2b can enter the transfer area 2a under the action of a conveying belt.
As shown in fig. 2 and 3, in the present embodiment, the transfer mechanism 4 includes a base 4a, the base 4a is driven to move by a linear module 5, both ends of the base 4a are respectively provided with a left retention plate 4b and a right fixing plate 4c extending forward, and the inner side of the right fixing plate 4c is movably equipped with a clip 4d, specifically, the clip 4d can move in the direction of the line connecting the left retention plate 4b and the right fixing plate 4c, and the area between the clip 4d and the left retention plate 4b is a holding space for holding the TIP head box 8. An elastic element 4e is provided between the clip 4d and the right fixing plate 4 c. The elastic member 4e can provide a clamping force for clamping the TIP head cartridge 8. The rear end of the right baffle plate 2e is provided with a limiting part 2e1, and in the process that the transfer mechanism 4 enters the transfer area 2a, the limiting part 2e1 and the clamping piece 4d are physically interfered so as to force the clamping space between the clamping piece 4d and the left retention plate 4b to be enlarged.
The specific working principle of the transfer mechanism 4 in the above embodiment is as follows: referring to fig. 2, when the transfer mechanism 4 approaches the transfer area 2a, the clip 4d is blocked by the limiting portion 2e1, the left retaining plate 4b continues to move forward further, and the distance between the clip 4d and the left retaining plate 4b is widened. After the transfer mechanism 4 completely enters the transfer area 2a, a clamping space formed between the clamping piece 4d and the left retention plate 4b is opposite to the waiting area 2b. Meanwhile, referring to fig. 8, in the final stage of the transfer mechanism 4 completely entering the transfer area 2a, the left retention plate 4b also pushes the limiting member 3 to rotate upwards, the waiting area 2b and the transfer area 2a are switched to be in a communicating state, and the TIP head box 8 on the waiting area 2b enters between the clamping piece 4d and the left retention plate 4b under the action of the conveyor belt. Then, the linear module 5 drives the transfer mechanism 4 to leave the transfer area 2a, and the clamping piece 4d moves towards the direction approaching the left retention plate 4b under the elastic thrust of the elastic element 4e, so as to firmly clamp the TIP head box 8 between the clamping piece 4d and the left retention plate 4 b. The transfer mechanism 4 is further moved rightward to carry the TIP head cartridge 8 to the loading area 1a.
As shown in fig. 2, the base platform 1 is provided with a guiding wheel 7 at a position close to the transfer area 2a, and the guiding wheel 7 can guide the TIP head box 8 in the process that the transfer mechanism 4 leaves the transfer area 2a, so that the TIP head box has an accurate relative position relationship in the loading area 1a, and further, the pipette of the analyzer can accurately load the TIP head.
As shown in fig. 2, 4 and 5, a horizontal support plate 1c is arranged below the loading area 1a, in this embodiment, the unloading mechanism 6 includes a motor 6a fixed on the horizontal support plate 1c, a swing arm 6c is fixedly sleeved on an output shaft of the motor 6a, the loading area 1a is provided with an avoidance opening 1a1, an upper end of the swing arm 6c is exposed above the loading area 1a through the avoidance opening 1a1, and a push rod 6b is installed at an upper end of the swing arm 6 c. After the TIP head on the TIP head cartridge 8 at the loading area 1a is used up, the motor 6a drives the push rod 6b to move forward, so that the discarded TIP head cartridge 8 can be sent to the recycling area 1b.
In the above embodiment of the unloading mechanism 6, since the TIP head cartridge 8 is in the clamped state, the clamping force may hinder the push rod 6b from pushing the TIP head cartridge 8 toward the recovery zone 1b. To this end, the present embodiment also provides a force release mechanism to release the clamping force of the elastic member 4e to the TIP head cartridge 8. The following are provided:
referring to fig. 4 and 5, a longitudinal support plate 1d is fixedly mounted on a horizontal support plate 1c, a limit deflector rod 6d is rotatably mounted on the longitudinal support plate 1d, a tension spring 6e is connected between the limit deflector rod 6d and the longitudinal support plate 1d, the tension spring 6e can pull the limit deflector rod 6d to rotate forwards, a driving part 6c1 protruding rightwards is fixedly arranged on a swing arm 6c, the driving part 6c1 is positioned in front of the limit deflector rod 6d, and in the process of rotating the swing arm 6c backwards, the driving part 6c1 can force the limit deflector rod 6d to rotate backwards against the resistance of the tension spring 6 e.
Based on the implementation structure, the working principle of the limit deflector rod 6d for unloading the clamping force of the TIP head box 8 is as follows: in the initial state, both the push rod 6b and the limit lever 6d are located behind the TIP head box 8, and the limit lever 6d is in the pressed state. After the TIP head of the TIP head box 8 is used up, the linear module 5 drives the transfer mechanism 4 to move rightwards until the clamping piece 4d of the transfer mechanism 4 exceeds the right end of the limit deflector rod 6 d. Then, the motor 6a drives the swing arm 6c to rotate forward, the driving part 6c1 releases the pressure on the limit deflector rod 6d, and the limit deflector rod 6d rotates forward under the traction action of the tension spring 6e until the limit deflector rod 6d physically interferes with the clamping piece 4d in the moving direction of the transfer mechanism 4. Then, the linear module 5 drives the transfer mechanism 4 to move leftwards, and in the process, the limit deflector rod 6d can block the clamping piece 4d to move leftwards, so that the distance between the clamping piece 4d and the left retention plate 4b is enlarged, and the clamping force on the TIP head box 8 is released. Finally, the motor 6a drives the swing arm 6c to rotate forward, and the push rod 6b can easily convey the TIP head box 8 to the recycling area 1b.
Finally, it should be noted that the above description is only a preferred embodiment of the present utility model, and that many similar changes can be made by those skilled in the art without departing from the spirit and scope of the utility model as defined in the appended claims.

Claims (10)

1. A TIP head box automatic handling module for chemiluminescence immunity analyzer, its characterized in that: comprising the following steps:
a base platform (1) provided with a loading area (1 a) and a recovery area (1 b);
a conveying platform (2) for conveying the TIP head box, wherein a limiting component (3) is movably arranged at a position, close to the tail end, of the conveying platform (2), the limiting component (3) divides the conveying platform (2) into a waiting area (2 b) and a transferring area (2 a), and the limiting component (3) can be opened so that the TIP head box in the waiting area (2 b) can enter the transferring area (2 a);
the transfer mechanism (4) is arranged on the basic platform (1) through a linear module (5), and the linear module (5) is used for driving the transfer mechanism (4) to reciprocate between the transfer area (2 a) and the loading area (1 a) so as to transfer the TIP head box of the transfer area (2 a) to the loading area (1 a); and
and the unloading mechanism (6) is arranged in the loading area (1 a) and is used for pushing the TIP head box in the loading area (1 a) to the recovery area (1 b).
2. The TIP cassette auto-loading and unloading module for a chemiluminescent immunoassay analyzer of claim 1 wherein: one end of the limiting component (3) is rotationally connected to one side of the conveying platform (2), and under the action of gravity, the other end of the limiting component (3) can be suspended above the conveying platform (2);
the limiting component (3) is provided with a protruding portion (3 a), and the transferring mechanism (4) can push the limiting component (3) to rotate upwards through the protruding portion (3 a) in the process that the transferring mechanism (4) enters the transferring area (2 a).
3. The TIP cassette auto-loading and unloading module for a chemiluminescent immunoassay analyzer of claim 1 wherein: the two sides of the conveying platform (2) are respectively provided with a left baffle plate (2 d) and a right baffle plate (2 e), and the left baffle plate (2 d) and the right baffle plate (2 e) are provided with avoidance notches (2 c) at positions corresponding to the transfer areas (2 a); the conveying direction of the conveying platform (2) is perpendicular to the moving direction of the transferring mechanism (4), and the transferring mechanism (4) can enter and exit the transferring area (2 a) through the avoidance notch (2 c).
4. The TIP cassette auto-loading module for a chemiluminescent immunoassay analyzer of claim 3 wherein: the transfer mechanism (4) comprises a base (4 a), a left retention plate (4 b) and a right fixing plate (4 c) which extend forwards are respectively arranged at two ends of the base (4 a), a clamping piece (4 d) is movably arranged on the inner side of the right fixing plate (4 c), an elastic element (4 e) is arranged between the clamping piece (4 d) and the right fixing plate (4 c), and force enabling the clamping piece (4 d) to move towards the direction close to the left retention plate (4 b) is applied to the elastic element (4 e).
5. The TIP cassette auto-loading module for a chemiluminescent immunoassay analyzer of claim 4 wherein: the rear end of the right baffle plate (2 e) is provided with a limiting part (2 e 1), and the spacing part (2 e 1) can force the interval between the clamping piece (4 d) and the left retention plate (4 b) to be enlarged in the process that the transfer mechanism (4) enters the middle transfer area (2 a).
6. The TIP cassette auto-loading and unloading module for a chemiluminescent immunoassay analyzer of claim 1 wherein: the unloading mechanism (6) comprises a motor (6 a) and a push rod (6 b) which is driven to move by the motor (6 a), the push rod (6 b) is positioned above the loading area (1 a), and the push rod (6 b) can move towards the rear end of the loading area (1 a) under the driving action of the motor (6 a).
7. The TIP cassette auto-loading and unloading module for a chemiluminescent immunoassay analyzer of claim 6 wherein: the motor (6 a) is fixedly arranged below the loading area (1 a), the swing arm (6 c) is fixedly sleeved on the output shaft of the motor (6 a), the loading area (1 a) is provided with the avoidance opening (1 a 1), the upper end of the swing arm (6 c) is exposed above the loading area (1 a) through the avoidance opening (1 a 1), and the push rod (6 b) is fixedly connected to the upper end of the swing arm (6 c).
8. The TIP cassette auto-loading module for a chemiluminescent immunoassay analyzer of claim 7 wherein: the utility model discloses a loading area, including loading district (1 a), horizontal bracket board (1 c) are gone up fixed mounting and are had vertical backup pad (1 d), motor (6 a) fixed mounting is gone up in horizontal bracket board (1 c), it is equipped with spacing driving lever (6 d) to rotate on vertical backup pad (1 d), be connected with extension spring (6 e) between spacing driving lever (6 d) and vertical backup pad (1 d), this extension spring (6 e) can pull spacing driving lever (6 d) and rotate forward, drive division (6 c 1) have been set firmly on swing arm (6 c), in-process that swing arm (6 c) rotated backward, drive division (6 c 1) can force spacing driving lever (6 d) to overcome the resistance of extension spring (6 e) and rotate backward.
9. The TIP cassette auto-loading and unloading module for a chemiluminescent immunoassay analyzer of claim 1 wherein: the base platform (1) is provided with guide wheels (7) at positions close to the transfer area (2 a).
10. The TIP cassette auto-loading and unloading module for a chemiluminescent immunoassay analyzer of claim 1 wherein: the conveying platform (2) is a belt conveying mechanism and is arranged on the base platform (1) in a sliding mode in a front-back mode in a drawer mode.
CN202223250651.5U 2022-12-05 2022-12-05 TIP head box automatic loading and unloading module for chemiluminescence immunity analyzer Active CN218995403U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223250651.5U CN218995403U (en) 2022-12-05 2022-12-05 TIP head box automatic loading and unloading module for chemiluminescence immunity analyzer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223250651.5U CN218995403U (en) 2022-12-05 2022-12-05 TIP head box automatic loading and unloading module for chemiluminescence immunity analyzer

Publications (1)

Publication Number Publication Date
CN218995403U true CN218995403U (en) 2023-05-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223250651.5U Active CN218995403U (en) 2022-12-05 2022-12-05 TIP head box automatic loading and unloading module for chemiluminescence immunity analyzer

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CN (1) CN218995403U (en)

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