CN218157928U - Single-person magnetic particle chemiluminescence reagent strip - Google Patents
Single-person magnetic particle chemiluminescence reagent strip Download PDFInfo
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- CN218157928U CN218157928U CN202222137145.9U CN202222137145U CN218157928U CN 218157928 U CN218157928 U CN 218157928U CN 202222137145 U CN202222137145 U CN 202222137145U CN 218157928 U CN218157928 U CN 218157928U
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Abstract
The utility model discloses a single-person magnetic particle chemiluminescence reagent strip, which comprises a reagent strip main body and a photometric unit, wherein the photometric unit is clamped on the reagent strip main body and is provided with a photometric hole and a first substrate hole; the reagent strip main body is sequentially provided with a first hole, a second hole, a clamping claw hole, a third hole, a reaction hole, a fourth hole, a first washing liquid hole and a magnetic bead washing hole from the first substrate hole to the other end, and the orifice outlines of the first hole, the second hole, the third hole, the reaction hole and the fourth hole are the same; the clamping jaw hole is close to the middle position of the reagent strip main body. The photometric hole of the utility model is positioned at the leftmost end of the reagent strip main body, so that photometric errors caused by the fact that the reaction reagent pollutes the photometric hole in the processes of sample adding and sampling are avoided, and the reliability of detection results is improved; the magnetic bead cleaning hole is positioned at the other end of the reagent strip main body and provides an inlet and outlet space for the magnet so as to realize the adsorption of the magnetic beads in the cleaning process and ensure the normal operation of the cleaning step; the orifice profiles of the holes are unified, and uniform puncture is facilitated.
Description
Technical Field
The utility model belongs to the technical field of external diagnosis and specifically relates to a single magnetism particle chemiluminescence reagent strip.
Background
The magnetic particle chemiluminescence immunoassay technology is a new analysis method combining a magnetic separation technology, a chemiluminescence technology and an immunoassay technology, is a high-sensitivity micro-determination technology which develops rapidly in the world in the last decade, and is used for detection and analysis technologies of various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins, medicines and the like.
At present, most of full-automatic chemical immunoassay devices based on a magnetic particle chemiluminescence immunoassay technology in the market detect multiple persons, and large-size detection reagents are concentrated in a reagent bin of the device and detect batch samples simultaneously during detection. At present, the detection mode has the following defects: firstly, the sample injection needle needs to repeatedly absorb different reagents used by detection items and add the reagents into different samples to process the samples, and the situation of mutual pollution between different reagents or different samples inevitably occurs; moreover, because the reagent is mostly in a large package specification of multiple people, when the detection amount of a sample is small, the reagent cannot be guaranteed to be used up in the valid period, unnecessary reagent waste is caused, and the reagent is partially volatilized by frequent bottle opening to influence the reliability of a detection result; furthermore, the full-automatic chemiluminescence device is used for batch detection, and cannot meet the emergency detection requirement of clinical emergency treatment or outpatient service samples.
POCT, point-of-care testing (point-of-care testing), refers to clinical testing and bedside testing (bedside testing) performed beside a patient, and has the advantages of rapidness, simplicity in use, comprehensive cost saving and the like, and is widely applied to the field of biological detection, such as cardiac marker POCT.
Most POCT instruments in the existing market are magnetic particle chemiluminescence detection instruments, reagent strips matched with the chemiluminescence detection instruments are single-person reagent strips (namely, each sample corresponds to one reagent strip), and reaction reagents, magnetic beads, washing liquor and the like are packaged in holes of the reagent strips so as to meet the detection requirements of the samples. A plurality of holes of current single part reagent strip integrate on the connecting plate, nevertheless generally have following problem when using:
firstly, before detection, a black photometric cup needs to be manually clamped in a mounting hole of a connecting plate, so that operation is troublesome; secondly, the shapes of all orifices of the reagent strip are greatly different, so that the reagent strip is not beneficial to uniform puncture; moreover, when the device is used, the device needs to be placed into a detection bin and positioned manually, is inaccurate in positioning, easy to rotate, inconvenient to place and easy to topple; after the detection is finished, the reagent strip needs to be manually taken out of the detection bin, and manual intervention is more; fourthly, the washing holes of some reagent strips are provided with reusable brush rods and bristles, and the bristles are used for cleaning residues in the washing holes, so that cross contamination is inevitable.
Disclosure of Invention
In view of the above, the utility model provides a single-person magnetic particle chemiluminescence reagent strip, which not only integrates the photometric hole on the reagent strip body, and does not need to install the photometric hole manually, but also unifies the orifice shapes of the holes, thereby facilitating the unified puncture; still have the clamping jaw hole, realize the centre gripping of reagent strip and take out through the clamping jaw hole, improved degree of automation.
In order to realize the purpose, the invention adopts the following technical scheme:
the single-person magnetic particle chemiluminescence reagent strip comprises a reagent strip main body made of a transparent material and a photometric unit made of a light-resistant material, wherein a sealing film is arranged on the reagent strip main body; the reagent strip comprises a reagent strip body, a photometric unit, a sealing film and a first substrate hole, wherein the photometric unit is clamped at one end of the reagent strip body and provided with the photometric hole and the first substrate hole;
the reagent strip main part certainly first hole, second hole, clamping jaw hole, third hole, reaction hole, fourth hole, first lotion hole and magnetic bead washing hole have in proper order to the other end in first substrate hole, first hole, second hole, third hole, reaction hole and the drill way profile in fourth hole is the same, is favorable to puncturing the head on the detecting instrument and punctures the membrane in unison, avoids appearing the incomplete condition of puncturing.
The clamping jaw hole is close to the middle position of the reagent strip main body, and the lower part of the hole wall of the clamping jaw hole is provided with a plurality of vertical through grooves so that the clamping jaw extends out, and the reagent strip is convenient to take, place and transfer.
In the above scheme, the photometric hole of the photometric unit is located at one end of the reagent strip main body, i.e., the photometric hole is located at the leftmost end of the reagent strip main body (i.e., the extreme end of the detection instrument), so that photometric errors caused by contamination of the photometric hole by a reaction reagent during sample addition and sampling processes are avoided, and the reliability of detection results is improved; the magnetic bead cleaning hole is positioned at the other end of the reagent strip main body and provides an in-and-out space for the magnet so as to realize the adsorption of the magnetic beads in the cleaning process and ensure the normal operation of the cleaning step;
the technical scheme also unifies the opening contour of each hole as much as possible so as to uniformly puncture a plurality of holes of the reagent strip as much as possible, thereby facilitating subsequent sampling and sample adding.
Preferably, the first, second and third bores are identical in construction and each comprise an upper cylindrical section and a lower conical section connected together; the first hole and the second hole are reagent holes packaged with reagents, and the second hole is a second washing liquid hole packaged with washing liquid; the third hole is a first dilution hole in which a sample diluent is packaged. The number of the second holes is 2-4, so that the cleaning requirements of different detection items are met; the number of the third holes is 2-4, and the sample can be diluted into different concentrations to meet the detection requirement.
Preferably, the first holes are two, namely a second substrate hole and a signal enhancer hole;
the fourth hole is big-end-up's conical structure, the fourth hole is three and is enzyme hole, second dilution hole and sample hole from left to right in proper order, just seal the membrane have with the opening that the sample hole corresponds.
During actual processing, cross-shaped positioning ribs are arranged at the bottoms of the signal reinforcing agent hole and the first washing liquid hole, the signal reinforcing agent hole and the first washing liquid hole are positioned at two ends of the reagent strip main body, and the positioning ribs have a supporting effect and are convenient for placing the reagent strip;
first hole, second hole, clamping jaw hole, third hole, reaction hole, fourth hole, first lotion hole and magnetic bead wash the hole between link together through the strengthening rib, improve the structural strength of reagent strip main part.
Preferably, an end of the sealing membrane extends to the location of the first substrate aperture to seal the first substrate aperture. The substrate A is pre-arranged in the first substrate hole of the photometric unit, so that the first substrate hole is sealed by using a sealing film during heat sealing, so that the substrate A is packaged, and the normal detection of a detection item is ensured;
during actual processing, the light measuring hole is in a conical structure with the taper smaller than 2 degrees, and the light measuring hole has a smaller taper, so that an internal light signal can be completely emitted, and a luminescent substance can be closest to a light measuring system of an instrument as far as possible under the condition of quantitative liquid; the inner diameter of the upper port of the photometric hole is controlled to be 4-8 mm, so that the contact between the outside air and the mixture in the photometric hole is avoided as much as possible, and the detection error is reduced; the wall thickness of the photometric hole is 0.4-0.8 mm, and heating incubation can be realized on the premise of meeting the light-shielding detection requirement, so that the reaction system in the photometric hole is rapidly heated.
Preferably, the upper edges of the first hole, the second hole, the clamping jaw hole, the third hole, the reaction hole, the fourth hole, the first washing liquid hole and the magnetic bead washing hole are provided with packaging bosses with the same height; all be provided with the same enhancement boss of height between first hole, second hole, clamping jaw hole, third hole, reaction hole and the fourth hole, just the encapsulation boss is with the highly uniform who strengthens the boss. When sealing the membrane, the encapsulation boss is convenient for heat-seal membrane, strengthens the boss and can consolidate and support and seal the membrane, further ensures to seal the membrane effect.
More preferably, the upper surface of the reagent strip main body is further provided with a circle of heat-sealing bulges which are lower than the packaging bosses, and the heat-sealing bulges completely surround the rest holes except the magnetic bead cleaning hole and the photometric unit, so that the sealing film bonded on the reagent strip main body is more attractive.
Preferably, the orifices of the first hole, the second hole, the third hole, the reaction hole and the fourth hole are annular orifices formed by alternately connecting straight segments and arc segments, and the contours of the orifices of the plurality of holes are consistent, so that a puncture head on a detection instrument can puncture and seal a membrane uniformly. During actual processing, the annular opening is preferably formed by alternately connecting two straight line segments with the same length and two arc segments with the same size;
during actual processing, magnetic bead cleaning hole top-down is big-end-up's frustum shape section, vertical magnetic bead enrichment section and big-end-up's arc end in proper order, just the last port of frustum shape section is square structure, and magnetic bead enrichment section has an enrichment face that is used for adsorbing the magnetic bead, just the contained angle of enrichment face and the axis of magnetic bead cleaning hole is less than 5.
In the scheme, the method comprises the following steps: the magnetic bead cleaning hole is provided with a frustum-shaped section, and the upper port of the frustum-shaped section is of a square structure, so that the capacity of the magnetic bead cleaning hole can be increased as much as possible to meet the cleaning requirement; the frustum-shaped section is similar to a horn mouth, and the frustum-shaped section is matched with the packaging boss at the opening edge of the frustum-shaped section, so that liquid is effectively prevented from splashing to the upper surface or adjacent holes when liquid is injected repeatedly in the cleaning process, and pollution is avoided;
the enrichment surface of the magnetic bead enrichment section is close to a vertical surface, the enrichment surface can realize the rapid enrichment of magnetic beads, and the wall hanging situation in the process of magnetic bead enrichment or movement can be avoided;
the magnetic bead cleaning hole is provided with an arc bottom with a big top and a small bottom, and can form a vortex to enable the magnetic bead and the reagent to be fully mixed and collected at the bottom when injecting liquid, so that the liquid pumping is more complete, and the residual quantity after the reagent is pumped is reduced.
Preferably, during actual processing, the reagent strip main body is of an integrally formed structure, and the photometric unit is of an integrally formed structure, so that the situation that the reagent strip is not assembled in place during use is avoided; additionally, the utility model discloses a reagent strip is disposable's consumptive material, avoids the pollution that used repeatedly brought.
Preferably, a positioning groove is formed in one end part, close to the light measuring cup, of the reagent strip main body and used for clamping a pin shaft on the reagent strip bearing table, and the fourth hole of the conical structure is inserted into the conical hole in the reagent strip bearing table, so that the positioning clamping of the reagent strip main body on the reagent strip bearing table is realized, and the reagent strip can be prevented from shaking or deviating in the operation process; another tip of reagent strip main part is handheld end, just handheld serving is provided with anti-skidding line, multiplicable frictional force, and handheld getting of being convenient for is put, avoids the slippage.
Compared with the prior art, the utility model has the advantages of it is following:
the utility model processes the photometric hole and the first substrate hole into an integrated structure, and encapsulates the first substrate hole on the reagent strip body, and the photometric hole is clamped on the reagent strip in an interference manner, thereby realizing the preassembly of the photometric hole on the reagent strip body, and the reagent strip does not need manual installation during detection, thereby simplifying the operation;
the photometric hole of the utility model is positioned at one end of the reagent strip main body, thus avoiding photometric errors caused by the pollution of reaction reagents to the photometric cup in the processes of sample adding and sampling, and improving the reliability of detection results; the magnetic bead cleaning hole is positioned at the other end of the reagent strip main body and provides an in-and-out space for the magnet so as to realize the adsorption of the magnetic beads in the cleaning process and ensure the normal operation of the cleaning step;
the contour and the appearance structure of the orifice of each hole are consistent, so that a plurality of holes of the reagent strip are uniformly punctured as much as possible, and subsequent sampling and sample adding are facilitated; in addition, a clamping jaw hole is formed in the middle position close to the reagent strip main body and matched with a clamping jaw of the POCT instrument, and the reagent strip is convenient to take, place and transfer.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a sectional view of fig. 1.
Fig. 3 is an enlarged schematic view of a portion a in fig. 1.
Fig. 4 is a schematic structural view of the light measuring unit in fig. 1.
Detailed Description
The core object of the present invention is to provide a single magnetic particle luminous reagent strip, which is described in detail below with reference to the accompanying drawings, in which the embodiment of the present invention is implemented on the premise of the technical solution of the present invention, and provides a detailed implementation and a specific operation process, but the protection scope of the present invention is not limited to the following embodiments.
As shown in fig. 1-2, the single-person magnetic particle chemiluminescent reagent strip according to the present embodiment includes a reagent strip main body made of a transparent material and a light measuring unit 1 made of a light-shielding material (the color of the light measuring unit 1 is preferably black, but may be other colors capable of shielding light), the light measuring unit 1 is interference-clamped in two mounting holes at the left end of the reagent strip main body, the light measuring unit 1 has a light measuring hole 1.1 and a first substrate hole 1.2 (a substrate a is packaged), and the reagent strip main body and the first substrate hole 1.2 have a sealing film 2; the right end portion of the reagent strip main body is a handheld end, and the handheld end is provided with anti-slip patterns F, so that the reagent strip main body can be conveniently held by hands to take and place. The light measuring unit 1 is clamped in the mounting hole of the reagent strip main body in an interference mode, the first substrate hole 1.2 is provided with the sealing film 2, the light measuring unit 1 does not need to be installed again manually when the light measuring unit is used, and the detection step is simplified.
As can be seen from fig. 1 and 4: the photometric hole 1.1 is a conical structure with taper less than 2 degrees, so that the internal optical signal can be completely emitted, and the distance between the luminescent substance and the photometric system of the instrument can be shortened as much as possible under the condition of quantitative liquid. In addition, the inner diameter of the upper port of the photometric hole 1.1 is controlled to be 4-8 mm, so that the contact between the outside air and the illuminant in the photometric hole can be avoided as much as possible, and the detection error is reduced;
the wall thickness of the photometric hole 1.1 is 0.4-0.8 mm, and the heating incubation can be realized on the premise of meeting the light-shielding detection requirement, so that the reaction system in the photometric hole is rapidly heated.
As shown in the figures 1-2, the reagent strip main body is sequentially provided with a first hole 3, a second hole 4, a clamping jaw hole 5, a third hole 6, a reaction hole 7, a fourth hole 8, a first washing liquid hole 9 and a magnetic bead washing hole 10 from left to right, and the orifice profiles of the first hole 3, the second hole 4, the third hole 6, the reaction hole 7 and the fourth hole 8 are the same, so that the puncture head on the detection instrument can puncture the sealing membrane 2 uniformly, and the incomplete puncture condition can be avoided.
In order to facilitate hole forming and processing, the orifices of the first hole 3, the second hole 4, the third hole 6, the reaction hole 7 and the fourth hole 8 are annular orifices formed by alternately connecting two straight-line segments with consistent lengths and two arc segments with consistent arc lengths and radiuses, and the contours of the orifices are consistent, so that a puncture head on a detection instrument can puncture the sealing membrane 2 uniformly;
in addition, in the embodiment, the photometric well 1.1 is located at the leftmost end of the reagent strip main body, so that photometric errors caused by the fact that a reaction reagent pollutes the photometric well 1.1 in the processes of sample adding and sampling are avoided, and the reliability of a detection result is improved; the magnetic bead cleaning hole 10 is located at the rightmost end of the reagent strip main body, and provides an in-and-out space for a magnet on an instrument, so that the adsorption of magnetic beads is realized, and the normal operation of a cleaning step is ensured.
As shown in fig. 1-2, the first well 3, the second well 4 and the third well 6 have the same structure and each include an upper cylindrical section and a lower tapered section connected together, and the capacities of the first well 3, the second well 4 and the third well 6 are determined by the items to be tested and the types of reagents packaged, but the embodiment is not limited to the capacities thereof.
In actual processing, two first holes 3 are provided, namely a second substrate hole 3.1 and a signal enhancer hole 3.2 which are respectively packaged with a substrate B from left to right; the second holes 4 are four and are second washing liquid holes for packaging washing liquid; the number of the third holes 6 is three, and the sample can be diluted into different concentrations to meet the detection requirement.
As can be seen from fig. 1-2, the fourth wells 8 are conical structures with large top and small bottom, the number of the fourth wells 8 is three, and the enzyme wells 8.1, the second dilution wells 8.2 and the sample wells 8.3 are arranged in sequence from left to right, and the sealing membrane 2 has openings corresponding to the sample wells 8.3, so as to facilitate the injection of the sample.
As can be seen from the combination of FIGS. 1-2, the reaction hole 7 is a conical structure with a taper smaller than 2 and has an arc bottom, which has a positioning function, and the reaction hole 7 is clamped on a positioning clamp on the reagent strip bearing table, which has a positioning function, so as to prevent the reagent strip from shaking or shifting during the operation.
As shown in fig. 1, a positioning groove 11.1 is formed at the left end of the reagent strip main body and can be matched with a pin shaft on the reagent strip bearing table in a positioning manner, so that the other end of the reagent strip main body is positioned, and the stability is improved;
The bottom in signal reinforcing agent hole 3.2 and first lotion hole 9 is provided with and is criss-cross location muscle 11.2 (the bottom highly uniform of location muscle 11.2), and signal reinforcing agent hole 3.2 and first lotion hole 9 are located the both ends of reagent strip main part, and stable support whole reagent strip, the placing of the reagent strip of being convenient for.
Preferably, the clamping jaw hole 5 is located between the second lotion hole and the third hole 6, and the hole wall lower part of the clamping jaw hole 5 is provided with a plurality of vertical through grooves formed so that the clamping jaw extends out, thereby facilitating taking, placing and transferring of reagent strips.
In other embodiments of the present invention: first hole 3, second lotion hole, clamping jaw hole 5, third hole 6, reaction hole 7, fourth hole 8, first lotion hole 9 link together through strengthening rib 11.3 between the hole 10 is washd to the magnetic bead, improve the structural strength of reagent strip main part.
During actual processing, the upper port of the first washing liquid hole 9 is a large-capacity hole with a square structure, so that the cleaning requirement of a detection item is met. As can be seen from FIGS. 1-3: the magnetic bead cleaning hole 10 is sequentially provided with a frustum-shaped section 10.1 with a large upper part and a small lower part, a vertical magnetic bead enrichment section 10.2 and an arc-shaped bottom 10.3 with a large upper part and a small lower part from top to bottom, the magnetic bead cleaning hole 10 is provided with the frustum-shaped section 10.1, and the upper port of the frustum-shaped section 10.1 is of a square structure, so that the capacity of the magnetic bead cleaning hole can be increased as much as possible to meet the cleaning requirement;
the frustum-shaped section of the magnetic bead cleaning hole 10 enables the whole hole to be similar to a horn mouth shape, and the frustum-shaped section 10.1 is matched with the splash-proof convex edge 10.4 at the opening edge of the frustum-shaped section, so that liquid is prevented from splashing to the upper surface or adjacent holes when liquid is injected repeatedly in the cleaning process, and further pollution is avoided;
the magnetic bead enrichment section 10.2 is provided with an enrichment surface 10.2a for adsorbing magnetic beads, the included angle between the enrichment surface 10.2a and the central axis of the magnetic bead cleaning hole 10 is less than 5 degrees, the enrichment surface 10.2a is close to a vertical surface, the rapid enrichment of the magnetic beads can be realized, and the wall hanging condition in the magnetic bead enrichment or moving process can be avoided;
10.3 at the bottom of the arc of magnetic bead washing hole 10 probably makes reagent form the vortex when annotating the liquid, realizes taking out the vortex mixing, makes reagent collection in the bottom after the washing, makes the drawing liquid more complete, reduces the reagent volume of remaining, further ensures the magnetic bead cleaning performance.
In other embodiments of the present invention, the upper edge of the first hole 3, the second hole 4, the clamping jaw hole 5, the third hole 6, the reaction hole 7, the fourth hole 8, the first washing liquid hole 9 and the magnetic bead cleaning hole 10 is provided with the encapsulation bosses 11.4 with the same height, that is, the upper surface of the reagent strip main body corresponding to each hole is provided with the encapsulation bosses 11.4 which are consistent with the structure of the hole opening and have an annular structure, so as to facilitate heat sealing of the sealing film 2; the joint of two adjacent holes can also have the encapsulation boss highly the same strengthens boss 11.5, consolidates and the supporting role, further ensures to seal membrane 2 effect.
More preferably, the upper surface of the reagent strip main body is further provided with a circle of heat-sealing bulges 11.6 with the height lower than that of the packaging boss 11.4, and the heat-sealing bulges completely surround the rest holes except the magnetic bead cleaning hole 10 and the photometric unit 1, so that the sealing film 2 bonded on the reagent strip main body is more attractive.
During actual processing, the reagent strip main body is of an integrally formed structure, and the photometric unit 1 is of an integrally formed structure, so that the situation that the reagent strip is not assembled in place in the use process is avoided; in addition, the utility model discloses a reagent strip is disposable consumptive material, avoids the pollution that used repeatedly brought.
It is to be noted that, unless otherwise expressly specified or limited in the description of the present invention, the terms "mounted," "connected," and "connected" when they are used are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; either directly or indirectly through intervening media, or may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art from the specific situation.
Finally, it should be emphasized that the above-described embodiments are merely preferred embodiments of the present invention, and not intended to limit the invention, and that, although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and equivalents may be made without inventive faculty to the embodiments described in the foregoing description, or that equivalents may be substituted for certain features thereof. Therefore, any modifications, equivalent replacements, improvements, etc., which are made within the spirit and principle of the present invention, should be included in the protection scope of the present invention.
Claims (10)
1. A single-person magnetic particle chemiluminescence reagent strip comprises a reagent strip main body made of a transparent material and a photometric unit made of a light-shielding material, wherein a sealing film is arranged on the reagent strip main body; the method is characterized in that: the photometric unit is clamped at one end of the reagent strip main body and is provided with a photometric hole and a first substrate hole;
the reagent strip main body is sequentially provided with a first hole, a second hole, a clamping claw hole, a third hole, a reaction hole, a fourth hole, a first washing liquid hole and a magnetic bead washing hole from the first substrate hole to the other end, and the orifice profiles of the first hole, the second hole, the third hole, the reaction hole and the fourth hole are the same;
the clamping jaw hole is close to the middle of the reagent strip main body, and the lower part of the hole wall of the clamping jaw hole is provided with a plurality of vertically-arranged through grooves so that the clamping jaw extends out.
2. The single-serving magnetic particle chemiluminescent reagent strip of claim 1 wherein: the first hole, the second hole and the third hole are identical in structure and respectively comprise an upper cylindrical section and a lower conical section which are connected together; the first hole and the second hole are reagent holes packaged with reagents, and the second hole is a second washing liquid hole packaged with washing liquid; the third hole is a first dilution hole in which a sample diluent is packaged.
3. The single-person magnetic particle chemiluminescent reagent strip according to claim 2, which is characterized in that: the number of the first holes is two, and the first holes are a second substrate hole and a signal intensifier hole respectively;
the fourth hole is big-end-up's conical structure, the fourth hole is three and is enzyme hole, second dilution hole and sample hole from left to right in proper order, just seal the membrane have with the opening that the sample hole corresponds.
4. The single-serving magnetic particle chemiluminescent reagent strip of claim 3 wherein: the bottoms of the signal reinforcing agent hole and the first washing liquid hole are provided with cross-shaped positioning ribs;
the first hole, the second hole, the clamping claw hole, the third hole, the reaction hole, the fourth hole, the first washing liquid hole and the magnetic bead washing hole are connected together through a reinforcing rib.
5. The single-serving magnetic particle chemiluminescent reagent strip of claim 1 wherein: the light measuring hole is of a conical structure with the taper smaller than 2 degrees, the inner diameter of the upper port of the light measuring hole is 4-8 mm, and the wall thickness of the light measuring hole is 0.4-0.8 mm; the sealing film is covered above the first substrate hole.
6. The single-person magnetic particle chemiluminescent reagent strip according to claim 1, which is characterized in that: packaging bosses with the same height are arranged at the upper hole edges of the first hole, the second hole, the clamping jaw hole, the third hole, the reaction hole, the fourth hole, the first washing liquid hole and the magnetic bead washing hole;
all be provided with the enhancement boss that highly the same between first hole, second hole, clamping jaw hole, third hole, reaction hole and the fourth hole, just the encapsulation boss is with the highly uniform who strengthens the boss.
7. The single-serving magnetic particle chemiluminescent reagent strip of claim 6 which is characterized in that: the upper surface of the reagent strip main body is also provided with a circle of heat-sealing bulges with the height lower than that of the packaging lug boss.
8. The single-serving magnetic particle chemiluminescent reagent strip of claim 1 wherein: the orifices of the first hole, the second hole, the third hole, the reaction hole and the fourth hole are consistent in shape and are all annular openings formed by alternately connecting straight-line sections and arc-shaped sections;
the magnetic bead cleaning hole is sequentially provided with a frustum-shaped section with a big top and a small bottom, a vertical magnetic bead enrichment section and an arc-shaped bottom with a big top and a small bottom from top to bottom, the upper end opening of the frustum-shaped section is of a square structure, the magnetic bead enrichment section is provided with an enrichment surface used for adsorbing magnetic beads, and the included angle between the enrichment surface and the central axis of the magnetic bead cleaning hole is smaller than 5 degrees.
9. The single-serving magnetic particle chemiluminescent reagent strip of claim 1 wherein: the reagent strip main part is the integrated into one piece structure, photometry unit is the integrated into one piece structure.
10. The single-serving magnetic particle chemiluminescent reagent strip of claim 1 wherein: a positioning groove is formed in one end part, close to the photometric hole, of the reagent strip main body; another tip of reagent strip main part is handheld end, just handheld serving is provided with anti-skidding line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222137145.9U CN218157928U (en) | 2022-08-15 | 2022-08-15 | Single-person magnetic particle chemiluminescence reagent strip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222137145.9U CN218157928U (en) | 2022-08-15 | 2022-08-15 | Single-person magnetic particle chemiluminescence reagent strip |
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| Publication Number | Publication Date |
|---|---|
| CN218157928U true CN218157928U (en) | 2022-12-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222137145.9U Active CN218157928U (en) | 2022-08-15 | 2022-08-15 | Single-person magnetic particle chemiluminescence reagent strip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218157928U (en) |
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2022
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