CN214750041U - Thin-layer identification chromatographic column for dandelion for pharmaceutical production - Google Patents

Abstract

The utility model discloses a thin-layer identification chromatographic column of dandelion for pharmaceutical production, including the chromatographic column pipe, the both ends surface of chromatographic column pipe all is provided with the joint, the guide way has been seted up to the one end of joint, it has the pressure cap to peg graft on the joint, the inboard of pressure cap is provided with the takeover, the bottom of pressure cap is provided with the guide bar, the surface of takeover is provided with the damping packing ring, lie in the both ends of chromatographic column pipe on the takeover and all be provided with the rubber circle, the outside of rubber circle is provided with the convex part, the bottom of takeover is pegged graft and is had the sieve, it has the shutoff to peg graft on the takeover; has the advantages that: the utility model discloses an in-process of pressing cap and joint spiro union, the guide bar is mutually supported with the guide way, and dislocation influences the leakproofness when preventing the spiro union, and the damping packing ring is mutually supported with the ring channel and is played limiting displacement, increases the stability of pressing cap and joint spiro union to rubber circle and convex part and the mutual block of spacing annular increase the leakproofness of pressing cap and articulate, guarantee the accuracy of the thin layer differentiation of chromatographic column.

Description

Thin-layer identification chromatographic column for dandelion for pharmaceutical production

Technical Field

The utility model relates to a technical field of pharmaceutical production equipment specifically is a chromatographic column is distinguished with thin layer of dandelion for pharmaceutical production.

Background

In the process of medicine production, in order to solve the problem of improvement of effective components of medicines, chromatography separation is generally used for identifying the thin layer of dandelion, a liquid chromatographic column is a core component in a liquid chromatograph, liquid is used as a mobile phase, a high-pressure infusion system is adopted, mobile phases such as single solvents with different polarities or mixed solvents with different proportions, buffer solutions and the like are pumped into the chromatographic column filled with a stationary phase, and after components in the column are separated, the mobile phases enter a detector for detection, so that analysis of a sample is realized.

Present chromatographic column connects department and connects through the screw thread, leads to probably to appear that the leakproofness is not good at the in-process of connecting, leads to the separating rate of chromatographic column slower, and the sieve in the chromatographic column filters impurity, and long-term the use needs to clear up or change, but the sieve is intraductal at the chromatographic column, and is very troublesome at the in-process of dismouting, for this reason the utility model provides a chromatographic column is distinguished with thin layer of dandelion for pharmaceutical production is used for solving above-mentioned problem.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a chromatographic column is distinguished with thin layer of dandelion for pharmaceutical production to solve the problem that proposes in the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a chromatographic column is distinguished with thin layer of dandelion for pharmaceutical production, includes the chromatographic column pipe, the both ends surface of chromatographic column pipe all is provided with the joint, the guide way has been seted up to the one end of joint, it has the pressure cap to peg graft on the joint, the inboard of pressing the cap is provided with the takeover, the bottom of pressing the cap is provided with the guide bar, the surface of takeover is provided with the damping packing ring, lie in the both ends of chromatographic column pipe and all be provided with the rubber circle on the takeover, the outside of rubber circle is provided with the convex part, the bottom of takeover is pegged graft and is had the sieve, it has the shutoff to peg graft on the takeover.

Preferably, the outer surface of the chromatographic column tube is sleeved with the anti-slip sleeve, annular grooves are formed in the inner sides of the two ends of the chromatographic column tube, the annular grooves are multiple, the annular grooves are distributed along the inner sides of the two ends of the chromatographic column tube in a distributed mode, the damping gaskets are of rubber layer structures, and the damping gaskets correspond to the annular grooves one by one.

Preferably, the guide grooves are arranged in a plurality of equal-angle distribution around the center line of the joint, the guide rods are of cylindrical structures and correspond to the guide grooves one to one, and the joint is in threaded connection with the pressing cap.

Preferably, the convex part and the rubber ring are of an integrally formed annular structure, limiting ring grooves are formed in the inner sides of the two ends of the chromatographic column tube, and the limiting ring grooves are arranged corresponding to the convex part and the rubber ring respectively.

Preferably, both sides of the sieve plate are provided with limiting blocks, and the connecting pipe penetrates through the limiting blocks and is provided with locking screws.

Preferably, the sealing plug is of a T-shaped rubber layer structure, one end of the sealing plug is provided with a pull ring, and the pull ring is of a circular ring structure.

Compared with the prior art, the beneficial effects of the utility model are that:

1. in the process of screwing the pressing cap and the joint, the guide rod and the guide groove are mutually matched to prevent dislocation from influencing the sealing property during screwing, the damping washer and the annular groove are mutually matched to play a limiting role to increase the stability of screwing the pressing cap and the joint, and the rubber ring, the convex part and the limiting annular groove are mutually clamped to increase the sealing property of connecting the pressing cap and the joint and ensure the accuracy of identifying the thin layer of the chromatographic column; the sieve plate is fixed at the bottom of the connecting pipe through the locking screw, so that the sieve plate is convenient to disassemble and assemble.

Drawings

Fig. 1 is a schematic structural view of the present invention;

FIG. 2 is an enlarged schematic view of the structure of FIG. 1;

fig. 3 is a schematic structural diagram of the chromatographic column tube of the present invention.

In the figure: a chromatography column 1; an anti-slip cover 11; an annular groove 12; a limit ring groove 13; a joint 2; a guide groove 21; a pressing cap 3; a connecting pipe 4; a guide rod 41; a damping washer 42; a rubber ring 43; a convex portion 44; a sieve plate 5; a stopper 51; a locking screw 52; a sealing plug 6; and a pull ring 61.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1 to 3, the present invention provides a technical solution: the utility model provides a chromatographic column is distinguished with thin layer of dandelion for pharmaceutical production, including chromatographic column pipe 1, the both ends surface of chromatographic column pipe 1 has all welded and has connected 2, antiskid cover 11 has been cup jointed to chromatographic column pipe 1's surface, antiskid cover 11 is favorable to the staff to the assurance of chromatographic column pipe 1, the both ends inboard of chromatographic column pipe 1 has all been established and has been seted up ring channel 12, ring channel 12 is provided with a plurality ofly, a plurality of ring channels 12 are arranged along chromatographic column pipe 1's both ends inboard and are distributed, guide way 21 has been seted up to the one end of connecting 2, guide way 21 is provided with a plurality ofly, a plurality of guide ways 21 are around the equal angular distribution of central line that connects 2.

The joint 2 is inserted with a pressing cap 3, the joint 2 is in threaded connection with the pressing cap 3, the inner side of the pressing cap 3 is provided with a connecting pipe 4, the bottom of the pressing cap 3 is welded with a guide rod 41, the guide rod 41 is in a cylindrical structure, the guide rod 41 is in one-to-one correspondence with the guide groove 21, the outer surface of the connecting pipe 4 is bonded with a damping gasket 42, the damping gasket 42 is in a rubber layer structure, the damping gasket 42 is in one-to-one correspondence with an annular groove 12, the connecting pipe 4 is positioned at two ends of the chromatographic column pipe 1 and is bonded with a rubber ring 43, the outer side of the rubber ring 43 is provided with a convex part 44, the convex part 44 and the rubber ring 43 are in an integrally formed annular structure, the inner sides of two ends of the chromatographic column pipe 1 are provided with limiting annular grooves 13, the limiting annular grooves 13 are respectively arranged corresponding to the convex part 44 and the rubber ring 43, the bottom of the connecting pipe 4 is inserted with a sieve plate 5, two sides of the sieve plate 5 are welded with limiting blocks 51, the connecting pipe 4 penetrates through the limiting blocks 51 and is fixed with locking screws 52, the connecting pipe 4 is spliced with a sealing plug 6, the sealing plug 6 is of a T-shaped rubber layer structure, one end of the sealing plug 6 is welded with a pull ring 61, and the pull ring 61 is of a circular ring structure.

The working principle is as follows: during practical use, the utility model discloses a hold antiskid cover 11 on chromatographic column pipe 1, will press cap 3 and joint 2 to carry out the spiro union, at the in-process of spiro union, guide bar 41 and guide way 21 are mutually supported, prevent that dislocation between press cap 3 and the joint 2 from influencing the leakproofness during the spiro union, the mutual cooperation of damping packing ring 42 and ring channel 12 plays limiting displacement to the spiro union between press cap 3 and the joint 2 simultaneously, increase the stability of pressing cap 3 and the spiro union of joint 2, and convex part 44 and rubber circle 43 and spacing ring channel 13 block each other, increase the leakproofness that press cap 3 and joint 2 are connected, thereby guarantee the accuracy of thin layer differentiation of chromatographic column, in addition insert closure 6 on takeover 4 through holding pull ring 61, realize the sealed when chromatographic column does not use; when the screen plate is disassembled, the pressing cap 3 is reversely screwed to realize the separation between the pressing cap 3 and the connector 2, and then the locking screw 52 on the screen plate 5 is disassembled to realize the disassembly of the screen plate 5, thereby being convenient for the cleaning or the replacement of the screen plate 5.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A thin layer identification chromatographic column of dandelion for drug production comprises a chromatographic column tube (1), and is characterized in that: the outer surface of the two ends of the chromatographic column tube (1) is provided with a connector (2), one end of the connector (2) is provided with a guide groove (21), a pressure cap (3) is inserted on the connector (2), the inner side of the pressure cap (3) is provided with a connecting tube (4), the bottom of the pressure cap (3) is provided with a guide rod (41), the outer surface of the connecting tube (4) is provided with a damping gasket (42), the two ends of the chromatographic column tube (1) on the connecting tube (4) are provided with rubber rings (43), the outer side of each rubber ring (43) is provided with a convex part (44), the bottom of the connecting tube (4) is inserted with a sieve plate (5), and the connecting tube (4) is inserted with a sealing plug (6).

2. The thin layer chromatography column for identifying dandelion for pharmaceutical production according to claim 1, wherein: the outer surface of chromatogram column pipe (1) has cup jointed antiskid cover (11), ring channel (12) have all been established to the both ends inboard of chromatogram column pipe (1), ring channel (12) are provided with a plurality ofly, and a plurality of ring channels (12) are arranged along the both ends inboard of chromatogram column pipe (1) and are distributed, damping packing ring (42) are rubber layer structure, one-to-one between damping packing ring (42) and ring channel (12).

3. The thin layer chromatography column for identifying dandelion for pharmaceutical production according to claim 1, wherein: the guide way (21) are provided with a plurality of, and a plurality of guide ways (21) distribute around the central line of connecting (2) equiangularly, guide bar (41) are cylindrical structure, one-to-one between guide bar (41) and the guide way (21), connect (2) and press threaded connection between cap (3).

4. The thin layer chromatography column for identifying dandelion for pharmaceutical production according to claim 1, wherein: convex part (44) and rubber circle (43) are integrated into one piece annular structure, spacing annular groove (13) have all been seted up to the both ends inboard of chromatogram column jacket (1), and spacing annular groove (13) correspond the setting with convex part (44) and rubber circle (43) respectively.

5. The thin layer chromatography column for identifying dandelion for pharmaceutical production according to claim 1, wherein: both sides of sieve (5) all are provided with stopper (51), run through stopper (51) and be provided with locking screw (52) on takeover (4).

6. The thin layer chromatography column for identifying dandelion for pharmaceutical production according to claim 1, wherein: the sealing plug (6) is of a T-shaped rubber layer structure, a pull ring (61) is arranged at one end of the sealing plug (6), and the pull ring (61) is of a circular ring structure.

Images