CN202700140U - Liquid chromatography column - Google Patents
Liquid chromatography column Download PDFInfo
- Publication number
- CN202700140U CN202700140U CN 201220354788 CN201220354788U CN202700140U CN 202700140 U CN202700140 U CN 202700140U CN 201220354788 CN201220354788 CN 201220354788 CN 201220354788 U CN201220354788 U CN 201220354788U CN 202700140 U CN202700140 U CN 202700140U
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- liquid
- column
- cap
- column jecket
- chromatographic column
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Abstract
The utility model discloses liquid chromatography column, and belongs to the technical field of liquid chromatography. The liquid chromatography column comprises a column pipe, two column caps, stationary phase adsorbing agents and filter seal elements, wherein the stationary phase adsorbing agents is filled in the column pipe, and the filter seal elements are respectively covered on two ends of the stationary phase adsorbing agents in seal mode. The column caps are respectively connected with two ends of the column pipe through threads, the column caps are provided with liquid inlets and liquid outlets, the liquid inlets and the liquid outlets are of an inner threaded structure, and the inner sides of two end portions of the column pipe are provided with stepped holes. The filter seal elements are arranged inside the stepped holes, one sides of the filter seal elements abut against the inner end faces of the column caps, and the other sides of the filter seal elements abut against the bottom faces of the stepped holes. The liquid chromatography column is simple in structure, convenient to assemble, and good in seal effects.
Description
Technical field
The utility model relates to a kind of liquid-phase chromatographic column, belongs to the liquid chromatography technology field.
Background technology
At present, liquid chromatography is a kind of physics or physical chemistry method for separating and analyzing, be particularly suitable for separating multi-component sample, it is a kind of very high and most widely used method of efficiency in various isolation technics, its principle is to utilize each component of mixture to have different distribution coefficients in two-phase, when two-phase is done relative motion, these materials carry out the purpose that repetitious distribution reaches separation in two-phase.Place and instrument that liquid-phase chromatographic column separates as chromatography, the quality of its performance has fundamentally determined the quality of separating effect.The how filling fine grain filler of liquid-phase chromatographic column commonly used is to obtain high-resolution, but the fluid resistance of fine grain filler is often very large, must adopt high-pressure pump so that mobile phase is forced to transport by pillar, so chromatographic column itself must have good pressure-resistant seal performance.
Chromatographic column structure is used the linear sealing connected mode with tapered sleeve usually in the market, and the processing technology of sealing structure requires high, the cost costliness.In order to obtain good sealing, what time followingly must guarantee: at first, must guarantee that the angle of tapered sleeve is less than the angle of the conical surface; Secondly the leading edge of tapered sleeve must be thin and sword is arranged, otherwise it will be difficult to be out of shape; In addition, with the cylindrical of the supporting column jecket of tapered sleeve, should keep good cylindrical, with the internal diameter of tapered sleeve, can slide and join, and should there be good fineness on surface, axial cut or groove etc. do not have.
Summary of the invention
The purpose of this utility model is to overcome the deficiencies in the prior art, provides a kind of simple in structure, easy to assembly, the liquid-phase chromatographic column of good sealing effect.
The technical scheme that realizes the utility model purpose is: a kind of liquid-phase chromatographic column, comprise column jecket, two caps, be filled in the fixedly phase adsorbent in column jecket and be sealed in the fixedly filtration potted component at phase adsorbent two ends, cap is connected to the two ends of column jecket by screw thread, cap is provided with the liquid entrance of female thread structure, inboard, column jecket both ends has shoulder hole, filtering potted component is arranged in shoulder hole, and the side and the cap inner face that filter potted component offset, and the bottom surface of opposite side and shoulder hole offsets.
Further, be provided with the first internal thread on the inwall of described cap, be provided with the first external screw thread matched with the first internal thread on described column jecket.
Further, be provided with the second external screw thread on the outer wall of described cap, be provided with the second internal thread matched with the second external screw thread on described column jecket.
Further, described filtration potted component is comprised of sieve plate and gasket seal, and sieve plate is inlaid in gasket seal.
Further, the lateral wall of described column jecket is provided with the reinforcement convex tendon, strengthens having two clamping faces on convex tendon.
Further, described cap and column jecket are made by polyetheretherketonematerials materials.
Further, described gasket seal is made by polytetrafluoroethylmaterial material.
After having adopted technique scheme, the mode that cap of the present utility model and column jecket match by internal and external threads is rotated and is connected with a joggle, easy to assembly, the bottom surface of column jecket upper shoulder hole and the inner face of cap are tightly connected by filtering potted component crimp, filter potted component and be unlikely to displacement up and down in shoulder hole, and then column jecket and cap form firmly seal, effectively prevented that fixedly the phase adsorbent spills and guarantee that mobile phase passes through, be convenient to large-scale production, overcome the difficult problem of the chromatographic column processing technology complexity of linear sealing connected mode design commonly used simultaneously.In addition, liquid entrance of the present utility model all adopts female thread structure, this interface directly and pipeline join, reduced or remitted the adapter between liquid entrance and pipeline, and can further improve withstand voltage properties; Column jecket and cap adopt polyetheretherketonematerials materials, this material had both had excellent chemical inertness, can in typical chromatogram environment, bear quite high operating pressure again, compare with polytetrafluoroethylmaterial material, polyetheretherketonematerials materials has the desired mechanical strength of chromatogram environment; With stainless steel material, compare, polyetheretherketonematerials materials can interference separation and purifying technique, and has outstanding chemical-resistant; Two clamping faces strengthening arranging on convex tendon are convenient to instrument and are clamped.
The accompanying drawing explanation
The structural representation of the first structure that Fig. 1 is liquid-phase chromatographic column of the present utility model;
The structural representation of the second structure that Fig. 2 is liquid-phase chromatographic column of the present utility model;
The structural representation that Fig. 3 is filtration potted component of the present utility model;
The A-A cutaway view that Fig. 4 is column jecket of the present utility model.
The specific embodiment
For content of the present utility model more easily is expressly understood, below according to specific embodiment also by reference to the accompanying drawings, the utility model is described in further detail,
Embodiment mono-
As shown in Figure 1, a kind of liquid-phase chromatographic column, comprise column jecket 7, two caps 1, be filled in the fixedly phase adsorbent 6 in column jecket 7 and be sealed in the fixedly filtration potted component 3 at phase adsorbent 6 two ends, cap 1 is connected to the two ends of column jecket 7 by screw thread, cap 1 is provided with the liquid entrance 1-1 of female thread structure, column jecket 7 inboards, both ends have shoulder hole 7-1, filtering potted component 3 is arranged in shoulder hole 7-1, and the side and cap 1 inner face that filter potted component 3 offset, and the bottom surface of opposite side and shoulder hole 7-1 offsets.Be provided with the first internal thread 1-2 on the inwall of cap 1, be provided with the first external screw thread 7-2 matched with the first internal thread 1-2 on described column jecket 7.
As shown in Figure 3, filter potted component 3 and be comprised of sieve plate 3-1 and gasket seal 3-2, sieve plate 3-1 is inlaid in gasket seal 3-2.
As shown in Figure 4, the lateral wall of column jecket 7 is provided with strengthens convex tendon 7-4, strengthens having two clamping face 7-4-1 on convex tendon 7-4.
Embodiment bis-
As shown in Figure 2, a kind of liquid-phase chromatographic column, comprise column jecket 7, two caps 1, be filled in the fixedly phase adsorbent 6 in column jecket 7 and be sealed in the fixedly filtration potted component 3 at phase adsorbent 6 two ends, cap 1 is connected to the two ends of column jecket 7 by screw thread, cap 1 is provided with the liquid entrance 1-1 of female thread structure, column jecket 7 inboards, both ends have shoulder hole 7-1, filtering potted component 3 is arranged in shoulder hole 7-1, and the side and cap 1 inner face that filter potted component 3 offset, and the bottom surface of opposite side and shoulder hole 7-1 offsets.Be provided with the second external screw thread 1-3 on the outer wall of cap 1, be provided with the second internal thread 7-3 matched with the second external screw thread 1-3 on column jecket 7.
As shown in Figure 3, filter potted component 3 and be comprised of sieve plate 3-1 and gasket seal 3-2, sieve plate 3-1 is inlaid in gasket seal 3-2.
As shown in Figure 4, the lateral wall of column jecket 7 is provided with strengthens convex tendon 7-4, strengthens having two clamping face 7-4-1 on convex tendon 7-4.
The mode that cap 1 of the present utility model and column jecket 7 match by internal and external threads is rotated and is connected with a joggle; easy to assembly; the bottom surface of column jecket 7 upper shoulder hole 7-1 and the inner face of cap 1 are tightly connected by filtering potted component 3 crimps; filter potted component 3 and be unlikely to displacement up and down in shoulder hole 7-1; and then column jecket 7 forms firmly seal with cap 1; effectively prevented that fixedly phase adsorbent 6 spills and guarantee that mobile phase passes through; be convenient to large-scale production, overcome the difficult problem of the chromatographic column processing technology complexity of linear sealing connected mode design commonly used simultaneously
.in addition, liquid entrance 1-1 of the present utility model all adopts female thread structure, this interface directly and pipeline join, reduced or remitted the adapter between liquid entrance 1-1 and pipeline, and can further improve withstand voltage properties; Column jecket 7 and cap 1 adopt polyetheretherketonematerials materials, this material had both had excellent chemical inertness, can in typical chromatogram environment, bear quite high operating pressure again, compare with polytetrafluoroethylmaterial material, polyetheretherketonematerials materials has the desired mechanical strength of chromatogram environment; With stainless steel material, compare, polyetheretherketonematerials materials can interference separation and purifying technique, and has outstanding chemical-resistant; Upper two the clamping face 7-4-1 that arrange of reinforcement convex tendon 7-4 are convenient to instrument and are clamped.
Above-described specific embodiment; the purpose of this utility model, technical scheme and beneficial effect are further described; institute is understood that; the foregoing is only specific embodiment of the utility model; be not limited to the utility model; all within spirit of the present utility model and principle, any modification of making, be equal to replacement, improvement etc., within all should being included in protection domain of the present utility model.
Claims (7)
1. a liquid-phase chromatographic column, comprise column jecket (7), two caps (1), be filled in the fixedly phase adsorbent (6) in column jecket (7) and be sealed in the fixedly filtration potted component (3) at phase adsorbent (6) two ends, cap (1) is connected to the two ends of column jecket (7) by screw thread, cap (1) is provided with the liquid entrance (1-1) of female thread structure, it is characterized in that: column jecket (7) inboard, both ends has shoulder hole (7-1), filtering potted component (3) is arranged in shoulder hole (7-1), and the side and cap (1) inner face that filter potted component (3) offset, the bottom surface of opposite side and shoulder hole (7-1) offsets.
2. liquid-phase chromatographic column according to claim 1, is characterized in that: be provided with the first internal thread (1-2) on the inwall of described cap (1), be provided with the first external screw thread (7-2) matched with the first internal thread (1-2) on described column jecket (7).
3. liquid-phase chromatographic column according to claim 1, is characterized in that: be provided with the second external screw thread (1-3) on the outer wall of described cap (1), be provided with the second internal thread (7-3) matched with the second external screw thread (1-3) on described column jecket (7).
4. liquid-phase chromatographic column according to claim 1, it is characterized in that: described filtration potted component (3) is comprised of sieve plate (3-1) and gasket seal (3-2), and sieve plate (3-1) is inlaid in gasket seal (3-2).
5. liquid-phase chromatographic column according to claim 1 is characterized in that: the lateral wall of described column jecket (7) is provided with strengthens convex tendon (7-4), strengthens having two clamping faces (7-4-1) on convex tendon (7-4).
6. liquid-phase chromatographic column according to claim 1, it is characterized in that: described cap (1), column jecket (7) are made by polyetheretherketonematerials materials.
7. liquid-phase chromatographic column according to claim 4, it is characterized in that: described gasket seal (3-2) is made by polytetrafluoroethylmaterial material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220354788 CN202700140U (en) | 2012-07-23 | 2012-07-23 | Liquid chromatography column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220354788 CN202700140U (en) | 2012-07-23 | 2012-07-23 | Liquid chromatography column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202700140U true CN202700140U (en) | 2013-01-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220354788 Expired - Lifetime CN202700140U (en) | 2012-07-23 | 2012-07-23 | Liquid chromatography column |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202700140U (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103191585A (en) * | 2013-04-01 | 2013-07-10 | 田景振 | Column chromatography device with warning function |
| CN103691151A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Detachable antiskid chromatographic column |
| CN104455415A (en) * | 2013-09-12 | 2015-03-25 | 道尼克斯索芙特隆公司 | Sealing mechanism and sealing method |
| CN105929095A (en) * | 2016-07-15 | 2016-09-07 | 烟台大学 | Chromatographic column used for liquid chromatography |
| CN111201187A (en) * | 2017-10-19 | 2020-05-26 | 百特基公司 | Chromatography cartridge sealing arrangement |
-
2012
- 2012-07-23 CN CN 201220354788 patent/CN202700140U/en not_active Expired - Lifetime
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103191585A (en) * | 2013-04-01 | 2013-07-10 | 田景振 | Column chromatography device with warning function |
| CN103191585B (en) * | 2013-04-01 | 2016-01-27 | 田景振 | A kind of column chromatography device with warning function |
| CN104455415A (en) * | 2013-09-12 | 2015-03-25 | 道尼克斯索芙特隆公司 | Sealing mechanism and sealing method |
| US10159910B2 (en) | 2013-09-12 | 2018-12-25 | Dionex Softron Gmbh | Sealing mechanism and sealing method |
| CN103691151A (en) * | 2013-12-05 | 2014-04-02 | 成都雅途生物技术有限公司 | Detachable antiskid chromatographic column |
| CN103691151B (en) * | 2013-12-05 | 2016-04-06 | 成都雅途生物技术有限公司 | Detachable antiskid chromatographic column |
| CN105929095A (en) * | 2016-07-15 | 2016-09-07 | 烟台大学 | Chromatographic column used for liquid chromatography |
| CN111201187A (en) * | 2017-10-19 | 2020-05-26 | 百特基公司 | Chromatography cartridge sealing arrangement |
| CN111201187B (en) * | 2017-10-19 | 2022-05-27 | 百特基公司 | Chromatography cartridge sealing arrangement |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130130 |