CN204428896U - Chromatographic column piston and preparative scale chromatography post - Google Patents
Chromatographic column piston and preparative scale chromatography post Download PDFInfo
- Publication number
- CN204428896U CN204428896U CN201520016827.1U CN201520016827U CN204428896U CN 204428896 U CN204428896 U CN 204428896U CN 201520016827 U CN201520016827 U CN 201520016827U CN 204428896 U CN204428896 U CN 204428896U
- Authority
- CN
- China
- Prior art keywords
- piston
- chromatographic column
- ring
- joint
- pipeline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
The utility model discloses a kind of chromatographic column piston, comprise the sieve plate, distributor, piston ring, piston head, joint, pipeline and the piston rod that connect successively.Piston head comprises relative first end and the second end, be threaded between first end with piston ring, the second end is provided with groove, piston head and joint are respectively along being axially provided with the first centre bore and the second centre bore that run through separately, joint is threaded with piston head in inside grooves, one end of pipeline is connected with joint screw thread, and the other end of pipeline passes from the inside of piston rod and extends to the outside of piston rod.Multiple elements of above-mentioned chromatographic column piston adopt and are threaded, and one end of pipeline is connected with piston head by independent joint, and the other end of pipeline is drawn from piston rod, the lead-out mode of this uniqueness, makes stationarity better.Relative to the piston of traditional dynamic axial compression column, the chromatographic column piston structure of the application is simple, and be convenient to change fallible component, durability is better.
Description
Technical field
The utility model relates to liquid chromatography technology field, particularly relates to a kind of chromatographic column piston and preparative scale chromatography post.
Background technology
Liquid chromatogram isolation technics is used to effectively be separated the blend sample with various ingredients, and core component is liquid chromatography separation column.Its separation principle is, blending ingredients sample is dissolved in a kind of mobile phase, mobile phase is under larger pressure condition, filling chromatograph packing material in chromatographic column is flow through with certain flow velocity, because chromatograph packing material is to the difference of the absorption affinity of different component, therefore different component flows through chromatograph packing material by with different flow velocitys, and in the detector of liquid chromatograph, detect that different component flows out the time of chromatographic column and the content of each component, thus the object reaching separation, detect.
Chromatographic column comprises analytic type chromatographic column and preparative scale chromatography post.Preparative scale chromatography post is the core component in preparative liquid chromatography system, decides performance and the efficiency of separation and purification.Wherein, dynamic axial compression chromatography technology is the important form in preparative scale chromatography post, and especially for the high pressure preparative column of more than internal diameter 5cm, it mainly adopts the form of dynamic axial compression.In dynamic axial compression chromatographic column, the structure of chromatographic column piston directly has influence on simple operation when filling post effect, chromatographic column sealing and installing/dismounting.The chromatographic column piston of traditional dynamic axial compression column has various ways, such as, distributor and piston Connection Block are integrated, and it is inner suction line to be received piston Connection Block, but various problem can be there is, such as cost is comparatively large, once the damage of screw thread or distributor will cause the replacing of whole parts; Or dismounting pipeline is very inconvenient.In addition, the piston of traditional dynamic axial compression column also and solidly can compress piston Connection Block pole and adopts screw thread to combine, but its pipeline is connected on the scarf of compression pole, and when making to install, piston stationarity is poor, more fragile piston.Therefore, the durability of the piston of traditional dynamic axial compression column is poor.
Utility model content
Based on this, be necessary for the problems referred to above, provide a kind of durability good chromatographic column piston.
A kind of chromatographic column piston, comprise the sieve plate connected successively, distributor, piston ring, piston head, joint, pipeline and piston rod, described piston head comprises relative first end and the second end, be threaded between described first end with described piston ring, described the second end is provided with groove, described piston head and described joint are respectively along being axially provided with the first centre bore and the second centre bore that run through separately, described joint is threaded with described piston head in described inside grooves, one end of described pipeline is connected with described joint screw thread, the other end of described pipeline passes from the inside of described piston rod and extends to the outside of described piston rod.
Wherein in an embodiment, described first end comprises the first adjacent convex shoulder and the second convex shoulder, and described first convex shoulder is threaded with described piston ring.
Wherein in an embodiment, described chromatographic column piston also comprises the first sealing ring be set on described second convex shoulder.
Wherein in an embodiment, described first sealing ring is spring sealed circle.
Wherein in an embodiment, described chromatographic column piston also comprises the second sealing ring being arranged in described groove.
Wherein in an embodiment, described second sealing ring is PTFE sealing ring.
Wherein in an embodiment, described piston ring is PTFE piston ring, PEEK piston ring or graphite filled PTFE piston ring.
Wherein in an embodiment, described piston rod is provided with for passing for described pipeline and extend to the opening of described piston rod outside away from one end of described joint.
Wherein in an embodiment, described chromatographic column piston also comprises the PTFE packing ring be threaded between described piston head with described piston rod and with the second end of described piston head.
In addition, also provide a kind of preparative scale chromatography post, comprise above-mentioned chromatographic column piston.
Multiple elements of above-mentioned chromatographic column piston adopt and are threaded, and one end of such as pipeline is connected with piston head by independent joint, convenient disassembly, and the other end of pipeline is drawn from piston rod, the lead-out mode of this uniqueness, makes stationarity better.Relative to the piston of traditional dynamic axial compression column, the chromatographic column piston structure of the application is simple, facilitates installing/dismounting, and be convenient to change fallible component, durability is better.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of chromatographic column piston in the utility model embodiment;
Fig. 2 is the schematic diagram of piston head in the utility model embodiment.
Detailed description of the invention
For enabling above-mentioned purpose of the present utility model, feature and advantage become apparent more, are described in detail detailed description of the invention of the present utility model below in conjunction with accompanying drawing.Set forth a lot of detail in the following description so that fully understand the utility model.But the utility model can be much different from alternate manner described here to implement, those skilled in the art can when doing similar improvement without prejudice to when the utility model intension, and therefore the utility model is by the restriction of following public specific embodiment.
It should be noted that, when element is called as " being fixed on " another element, directly can there is element placed in the middle in it on another element or also.When an element is considered to " connection " another element, it can be directly connected to another element or may there is centering elements simultaneously.
Unless otherwise defined, all technology used herein and scientific terminology are identical with belonging to the implication that those skilled in the art of the present utility model understand usually.The object of the term used in description of the present utility model herein just in order to describe specific embodiment, is not intended to be restriction the utility model.Term as used herein " and/or " comprise arbitrary and all combinations of one or more relevant Listed Items.
Chromatographic column piston 100 of the present utility model comprises the sieve plate 110, distributor 120, piston ring 130, first sealing ring 140, piston head 150, second sealing ring 160, joint 170, pipeline 180, PTFE packing ring 190 and the piston rod 1110 that connect successively, as shown in Figure 1.Piston ring 130 is provided with distributor 120 and sieve plate 110 from inside to outside successively.Piston ring in the present embodiment is PTFE piston ring, PEEK piston ring or graphite filled PTFE piston ring.
Piston head 150 comprises relative first end 151 and the second end 152, as shown in Figure 2.First end 151 comprises the first adjacent convex shoulder 1511 and the second convex shoulder 1512.The outer surface of the first convex shoulder 1511 is screw thread, and and is threaded connection between piston ring 130.First sealing ring 140 is set on the second convex shoulder 1512.The first sealing ring 140 in the present embodiment is spring sealed circle, and being conducive to increases closure.But it is not as limit, the sealing ring of sealing function can also can be realized for other.
The structure of above-mentioned sieve plate 110, distributor 120, piston ring 130 and the first sealing ring 140 is simple, is easy to dismounting, convenient cleaning, and ensure that good sealing.
The second end 152 of piston head 150 is provided with groove 153.Second sealing ring 160 is arranged in groove 153, for ensureing the sealing between joint 170 and piston head 150.The second sealing ring 160 in the present embodiment is PTFE sealing ring, but not as limit, can also can realize the sealing ring of sealing function for other.Piston head 150 is axially provided with the first centre bore 151 run through along it.Joint 170 is axially provided with the second centre bore 171 run through along it.First centre bore 151 and the second centre bore 171 make whole chromatographic column piston 100 inside be communicated with.The inside of groove 153 is set to screw thread, and joint 170 is threaded with piston head 150 in groove 153 inside.Joint 170 is design separately, is convenient to the replacing of easily worn part, saves overall replacement cost.
One end of pipeline 180 realizes being connected with the external screw thread of joint 170 by internal thread.The other end of pipeline 180 passes from the inside of PTFE packing ring 190 and piston rod 1110 and extends to the outside of piston rod 1110.And PTFE packing ring 190 is threaded between piston head 150 with piston rod 1110 and with the second end 152 of piston head 150.Piston rod 1110 is provided with for passing for pipeline 180 and extend to the opening 1111 of piston rod 1110 outside away from one end of joint 170.The lead-out mode of the pipeline 180 of this uniqueness, makes the stationarity of chromatographic column piston 100 better, increases its durability.
Adopt between multiple elements of above-mentioned chromatographic column piston 100 and be threaded, one end of such as pipeline 180 is connected with piston head 150 by independent joint 170, convenient disassembly, and the other end of pipeline 180 is drawn from piston rod 1110, the lead-out mode of this uniqueness, makes stationarity better.Relative to the piston of traditional dynamic axial compression column, the chromatographic column piston structure of the application is simple, facilitates installing/dismounting, and be convenient to change fallible component, durability is better.
In addition, the application also provides a kind of preparative scale chromatography post, comprises above-mentioned chromatographic column piston.The preparative scale chromatography rod structure of the above-mentioned chromatographic column piston of this use is simple, facilitates installing/dismounting, and be convenient to change fallible component, durability is better.
The above embodiment only have expressed several embodiment of the present utility model, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the utility model the scope of the claims.It should be pointed out that for the person of ordinary skill of the art, without departing from the concept of the premise utility, can also make some distortion and improvement, these all belong to protection domain of the present utility model.Therefore, the protection domain of the utility model patent should be as the criterion with claims.
Claims (10)
1. a chromatographic column piston, it is characterized in that, comprise the sieve plate connected successively, distributor, piston ring, piston head, joint, pipeline and piston rod, described piston head comprises relative first end and the second end, be threaded between described first end with described piston ring, described the second end is provided with groove, described piston head and described joint are respectively along being axially provided with the first centre bore and the second centre bore that run through separately, described joint is threaded with described piston head in described inside grooves, one end of described pipeline is connected with described joint screw thread, the other end of described pipeline passes from the inside of described piston rod and extends to the outside of described piston rod.
2. chromatographic column piston according to claim 1, is characterized in that, described first end comprises the first adjacent convex shoulder and the second convex shoulder, and described first convex shoulder is threaded with described piston ring.
3. chromatographic column piston according to claim 2, is characterized in that, described chromatographic column piston also comprises the first sealing ring be set on described second convex shoulder.
4. chromatographic column piston according to claim 3, is characterized in that, described first sealing ring is spring sealed circle.
5. chromatographic column piston according to claim 1, is characterized in that, described chromatographic column piston also comprises the second sealing ring being arranged in described groove.
6. chromatographic column piston according to claim 5, is characterized in that, described second sealing ring is PTFE sealing ring.
7. chromatographic column piston according to claim 1, is characterized in that, described piston ring is PTFE piston ring, PEEK piston ring or graphite filled PTFE piston ring.
8. chromatographic column piston according to claim 1, is characterized in that, described piston rod is provided with for passing for described pipeline and extend to the opening of described piston rod outside away from one end of described joint.
9. chromatographic column piston according to claim 1, is characterized in that, described chromatographic column piston also comprises the PTFE packing ring be threaded between described piston head with described piston rod and with the second end of described piston head.
10. a preparative scale chromatography post, is characterized in that, comprises the chromatographic column piston according to any one of claim 1 ~ 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520016827.1U CN204428896U (en) | 2015-01-09 | 2015-01-09 | Chromatographic column piston and preparative scale chromatography post |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520016827.1U CN204428896U (en) | 2015-01-09 | 2015-01-09 | Chromatographic column piston and preparative scale chromatography post |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204428896U true CN204428896U (en) | 2015-07-01 |
Family
ID=53596818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520016827.1U Active CN204428896U (en) | 2015-01-09 | 2015-01-09 | Chromatographic column piston and preparative scale chromatography post |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204428896U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109358147A (en) * | 2018-12-25 | 2019-02-19 | 成都格莱精密仪器有限公司 | A kind of chromatographic column that can quickly load |
-
2015
- 2015-01-09 CN CN201520016827.1U patent/CN204428896U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109358147A (en) * | 2018-12-25 | 2019-02-19 | 成都格莱精密仪器有限公司 | A kind of chromatographic column that can quickly load |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN204428896U (en) | Chromatographic column piston and preparative scale chromatography post | |
| CN202700140U (en) | Liquid chromatography column | |
| CN105004823A (en) | Liquid-phase chromatographic column assembly joint and application thereof | |
| CN202145204U (en) | Liquid phase chromatographic column | |
| CN205815185U (en) | A kind of liquid chromatography separation column | |
| CN203355360U (en) | Medium-pressure chromatographic column | |
| CN204359762U (en) | The syndeton of preparative scale chromatography post and preparative scale chromatography post | |
| CN203517075U (en) | Pipeline connecting assembly | |
| CN207297319U (en) | Liquid chromatograph plunger rod cleaning structure | |
| CN202122852U (en) | Liquid chromatography separation column | |
| CN204428895U (en) | The hermetically-sealed construction of preparative scale chromatography post and preparative scale chromatography post | |
| CN202453332U (en) | High performance liquid-phase preparative chromatographic column | |
| CN104597156A (en) | Two-column system gas chromatograph | |
| CN202141702U (en) | Liquid phase chromatographic column | |
| CN204405611U (en) | Dual column system gas chromatograph | |
| CN208294869U (en) | A kind of sealing structure of adjustable position hydraulic cylinder | |
| CN209204735U (en) | It is a kind of to prepare chromatographic column | |
| CN203115119U (en) | Novel vent valve structure of manifold | |
| CN203614947U (en) | Engine joint component | |
| CN202141703U (en) | Liquid phase chromatographic column | |
| CN201671906U (en) | Cylinder with variable pressure | |
| CN102261530A (en) | Seal connecting device of diesel engine fuel oil metal pipe | |
| CN203797064U (en) | Novel joint check valve | |
| CN202851515U (en) | Cylinder piston | |
| CN204829033U (en) | Take sealing pipe fitting of bull crossover sub |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 215123 Room 401, building C11, Biological Nanotechnology Park, 218 Xinghu street, industrial park, Suzhou, Jiangsu Province Patentee after: Suzhou saifen Technology Co.,Ltd. Address before: 215123 Room 401, building C11, Biological Nanotechnology Park, 218 Xinghu street, industrial park, Suzhou, Jiangsu Province Patentee before: SEPAX TECHNOLOGIES (SUZHOU) Co.,Ltd. |
|
| CP02 | Change in the address of a patent holder | ||
| CP02 | Change in the address of a patent holder |
Address after: 215323 No. 11, Jixian street, Suzhou Industrial Park, Jiangsu Province Patentee after: Suzhou saifen Technology Co.,Ltd. Address before: 215123 Room 401, building C11, Biological Nanotechnology Park, 218 Xinghu street, industrial park, Suzhou, Jiangsu Province Patentee before: Suzhou saifen Technology Co.,Ltd. |