CN214585470U

CN214585470U - Biochemical test paper tube

Info

Publication number: CN214585470U
Application number: CN202120198008.9U
Authority: CN
Inventors: 钱锐泽; 韦里; 周中人
Original assignee: Shanghai Miaoling Bioengineering Co ltd; Quicking Biotech Co ltd
Current assignee: Shanghai Miaoling Bioengineering Co ltd; Quicking Biotech Co ltd
Priority date: 2020-06-19
Filing date: 2021-01-25
Publication date: 2021-11-02
Anticipated expiration: 2031-01-25
Also published as: CN112816681B; CN112816681A

Abstract

The utility model relates to a biochemical test paper tube, which comprises a tube part and a cover part; the pipe portion includes: a solution chamber; a test paper fixing member; the first positioning part is arranged at the bottom of the solution cavity; and the second positioning parts are arranged on the upper part of the first positioning part. The sample tube placed in the solution cavity is positioned by the first positioning part and the second positioning part, so that a sample to be detected in the sample tube is mixed with a solution in the solution cavity in a sealed state, the exposure time of the sample to be detected is reduced, and the infection risk is reduced; the detection process is carried out in a totally-enclosed manner, and after the detection is finished, the biochemical test paper tube can be directly discarded as medical waste, so that the environment pollution is avoided, and the influence of high-hazard substances in the test tube on the life safety is prevented.

Description

Biochemical test paper tube

Technical Field

The utility model relates to a short-term test technical field especially relates to a biochemical test paper pipe.

Background

In vitro diagnosis or in vitro detection, a combination of a chromatography test paper and a test tube is usually used as a rapid diagnosis tool or a rapid detection tool in order to obtain a qualitative result quickly. Generally, the sample to be diagnosed or tested will usually have some risks, such as toxicity and infectivity. The used test tube is treated as medical waste.

However, the related art test tube has some drawbacks. For example, in the detection, it is necessary to perform operations such as preparation of a reaction solution and sampling, which is time-consuming and labor-consuming. In addition, during detection, a sample to be detected is mostly in an exposed state, and the health of detection personnel is easily damaged. If a throat swab is used for collecting a sample for novel coronavirus detection, the throat swab is directly exposed to the air or is temporarily stored by using a sealed container; when the test is performed, the pharyngeal swab is taken out of the sealed container and put into a test device for testing. The short exposure of the throat swab during removal increases the risk of infection to the detector.

At present, no effective solution is provided aiming at the problems of multiple detection steps, low detection efficiency and high infection risk caused by the exposure of a sample to be detected when a reaction solution is used as it is in the related art.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a biochemical test paper tube aiming at the defects in the prior art.

In order to achieve the purpose, the utility model adopts the technical proposal that:

the utility model provides a biochemical test paper tube, which comprises a tube part and a cover part;

the tube portion includes:

a solution chamber;

a test paper fixing member, wherein the top of the solution chamber is communicated with the top of the test paper fixing member under the condition that the cover part seals the tube part;

a first positioning member disposed at a bottom of the solution chamber;

the second positioning parts are arranged in the solution cavity and positioned at the upper parts of the first positioning parts, and each second positioning part is connected with the side wall of the solution cavity;

wherein, under the condition that the cover part closes the tube part, the cover part is in interference fit with the tube part, and under certain vacuum conditions, the solution in the tube part is kept for at least 10 minutes without leakage.

In some of these embodiments, the solution in the tubing portion remains leak-free for at least 10 minutes under a vacuum of 3 kg.

In some of these embodiments, the tube further comprises:

the third positioning parts are arranged at the bottom of the solution cavity and are not in contact with the first positioning parts and the second positioning parts, the heights of the third positioning parts are larger than those of the first positioning parts, the top ends of the third positioning parts are positioned below the bottoms of the second positioning parts, and each third positioning part is connected with the bottom wall of the solution cavity and the side wall of the solution cavity.

In some of the embodiments, the first positioning part is arranged in the middle of the bottom of the solution cavity and is connected with the bottom wall of the solution cavity; and/or

A plurality of first positioning parts are arranged at the bottom of the solution cavity and connected with the bottom wall of the solution cavity and the side wall of the solution cavity

In some of these embodiments, a number of the first positioning members form a first chamber around;

a plurality of second positioning parts surround to form a second chamber;

the axis of the first chamber is coaxial with the axis of the second chamber, or the horizontal distance between the axis of the first chamber and the axis of the second chamber is less than 3 mm.

In some of these embodiments, the tube further comprises:

the puncture component comprises a tip and/or a blade, and the puncture component and the first positioning component are matched and fixed at the bottom of the solution cavity.

In some of the embodiments, the number of the blades is several, and several of the blades are arranged in parallel; and/or

The blade parts are arranged in a crossed manner.

In some embodiments, the biochemical test paper tube further comprises:

the sample tube, the sample tube inserts solution chamber, a plurality of the second locating component with the lateral wall of sample tube cooperatees in order to right the sample tube leads and fixes a position, and is a plurality of under the effect of second locating component, the bottom of sample tube orientation with puncture the most advanced and/or the cutting part contact of part.

In some of these embodiments, the bottom of the sample tube is planar.

In some of these embodiments, a number of the third positioning members cooperate with a sidewall of the sample tube with the sample tube inserted into the solution chamber.

In some of these embodiments, the cover comprises:

a pressing member provided inside a top surface of the lid portion;

in the process that the cover part closes the tube part, the pressing part contacts the top of the sample tube and pushes the sample tube to be downwards inserted into the solution cavity in the matching guide of the plurality of second positioning parts and the side wall of the sample tube, the bottom of the sample tube is punctured by the sharp end and/or the blade part of the puncturing part, and the sharp end and/or the blade part of the puncturing part is inserted into the sample tube by at least 1 mm.

In some of these embodiments, where the bottom of the sample tube is pierced by the tip and/or blade of the piercing member, the bottom end of the sample tube is cut by the tip and/or blade of the piercing member with at least one slit extending from the bottom end of the sample tube to the inner wall of the sample tube.

In some of these embodiments, the piercing member further comprises:

a flow channel disposed in a recessed portion between a tip of the piercing member and/or a raised portion of the blade;

wherein, when the tip and/or blade of the puncture member is inserted into the sample tube, a gap is present between the flow channel and the ruptured inner wall of the sample tube, so that the internal solution of the sample tube flows into the solution chamber from the gap, the flow channel.

In some of these embodiments, the tube further comprises:

the sealing platform is arranged on the end face of the top of the solution cavity and completely surrounds the solution cavity;

the sealing platform is at a distance from the bottom of the cover part in a state where the cover part closes the tube part.

In some of these embodiments, the horizontal distance between the sealing land and the wall of the tube portion is at least 0.5mm and the vertical distance between the sealing land and the wall of the tube is at least 0.5 mm.

In some of these embodiments, the sealing land has a width of at least 1 mm.

In some of these embodiments, the sealing land is not in contact with the bottom of the cap with the cap closing the tube.

In some of these embodiments, the vertical distance between the sealing land and the bottom of the cap portion is at least 1mm with the cap portion closing the tube portion.

In some of these embodiments, the tube further comprises:

a sealing membrane connected with the sealing platform to seal the solution chamber.

In some of these embodiments, the tube further comprises:

a first fitting member provided on an inner wall of an upper portion of the tube portion;

the cover portion further includes:

a sealing member provided on an outer wall of the lid section;

a second fitting member provided on an outer wall of the lid portion;

wherein, in a case where the lid portion closes the tube portion, the sealing member is connected to the first fitting member, and the second fitting member is fitted to the first fitting member; alternatively, the sealing member is connected to the inner wall of the tube portion in a sealing manner, and the second fitting member is fitted to the first fitting member.

In some of these embodiments, the sealing member is an annular projection.

In some of these embodiments, the first engagement member is an annular groove and the second engagement member is an annular projection.

In some of these embodiments, the width of the cross-section of the second fitting component is less than the width of the cross-section of the sealing component.

In some embodiments, the number of the first engaging parts is several, and several of the first engaging parts are arranged at intervals along the axial direction of the tube part.

In some embodiments, the number of the second fitting parts is several, and several of the second fitting parts are arranged at intervals in the axial direction of the cover part.

In some of these embodiments, the cover further comprises:

a cavity formed by an inner surface of the cover portion bulging outward.

In some of these embodiments, further comprising:

an opening prevention member provided at a top of the tube part and/or a stopper of the cap part;

wherein the cap is prevented from being separated from the tube by the opening prevention member in a state where the cap closes the tube.

In some embodiments, the biochemical test paper tube further comprises:

the biochemical test paper is arranged inside the test paper fixing part;

wherein, under the condition that the cover part seals the tube part, the sample solution receiving end of the biochemical test paper is close to the cover part.

In some of these embodiments, the sample solution receiving end of the biochemical test strip extends upward and has a height greater than the orifice of the tube portion.

In some embodiments, the difference between the length of the biochemical test paper and the height of the opening of the tube is 1-5 mm.

In some of these embodiments, the biochemical test strip is an immunochromatographic test strip comprising:

a substrate;

a chromatographic membrane disposed on an upper surface of the substrate;

the water absorption pad is arranged on the lower surface of the base material;

wherein the chromatographic membrane and the absorbent pad are contacted at the end of the substrate and solution transfer is performed.

In some of these embodiments, the end of the chromatographic membrane is a distance beyond the end of the substrate;

the tail end of the absorbent pad exceeds the tail end of the base material by a certain distance;

the end of the chromatographic membrane is contacted with the end of the absorbent pad and solution transfer is carried out.

In some of the embodiments, the chromatographic membrane is further disposed on the lower surface of the substrate, and the ends of the chromatographic membrane and the ends of the absorbent pad are in contact with each other on the lower surface of the substrate and perform solution transfer.

In some of these embodiments, the absorbent pad is further disposed on the upper surface of the substrate, and the ends of the chromatographic membrane and the ends of the absorbent pad are in contact and solution transfer on the upper surface of the substrate.

In some of these embodiments, the immunochromatographic strip further comprises:

a conjugate pad disposed on the substrate, an end of the conjugate pad contacting a front end of the chromatographic membrane and delivering a solution to the chromatographic membrane;

a guide film disposed on the substrate, a distal end of the guide film contacting a front end of the conjugate pad and transferring a solution to the conjugate pad;

wherein the solution chromatography speed of the guide membrane is less than that of the binding pad.

In some of these embodiments, the guide film has a thickness of less than 0.15 mm.

a sample pad disposed on the substrate, a distal end of the sample pad contacting a front end of the guide membrane and transferring a solution to the guide membrane.

a sample pad disposed on the substrate, a distal end of the guide membrane contacting a front end of the sample pad and delivering a solution to the sample pad.

a sample limiting membrane disposed on the substrate, a distal end of the sample limiting membrane contacting a front end of the guide membrane and transferring a solution to the guide membrane.

In some of these embodiments, the sample limiting membrane has a liquid imbibition saturation volume of 2 to 20 μ l.

and the filter pad is arranged on the base material, and the tail end of the guide membrane is in contact with the front end of the filter pad and transmits the solution to the filter pad.

and the water retaining cushion is arranged close to the front end of the guide film.

In some embodiments, the water retaining pad of the immunochromatographic test strip fills the gap between the immunochromatographic test strip and the strip fixing member.

a transparent protective film covering at least the chromatographic carrier and the conjugate pad.

In some of these embodiments, the chromatographic membrane comprises a detection line and a quality control line arranged in sequence.

In some of these embodiments, a lower surface of the distal end of the bib pad contacts an upper surface of the distal end of the chromatographic membrane; or

The upper surface of the tail end of the water absorption pad is contacted with the lower surface of the tail end of the chromatographic membrane.

In some of these embodiments, the lower surface of the distal end of the conjugate pad is in contact with the upper surface of the leading end of the chromatographic membrane; or

The upper surface of the distal end of the conjugate pad is in contact with the lower surface of the leading end of the chromatographic carrier.

In some of these embodiments, a lower surface of the tip of the guide film is in contact with an upper surface of the front end of the bonding pad; or

An upper surface of a tip of the guide film is in contact with a lower surface of a front end of the bonding pad.

In some of these embodiments, a lower surface of a tip of the guide membrane is in contact with an upper surface of a front end of the filter pad; or

The upper surface of the end of the guide membrane is in contact with the lower surface of the front end of the filter pad.

In some of these embodiments, the lower surface of the distal end of the filter pad is in contact with the umbo surface of the front end of the conjugate pad; or

The upper surface of the end of the filter pad is in contact with the lower surface of the front end of the conjugate pad.

In some of these embodiments, a lower surface of the distal end of the sample pad is in contact with an upper surface of the leading end of the guide membrane; or

An upper surface of a distal end of the sample pad is in contact with a lower surface of a leading end of the guide film.

In some of these embodiments, the lower surface of the distal end of the sample pad is in contact with the upper surface of the leading end of the conjugate pad; or

The upper surface of the distal end of the sample pad is in contact with the lower surface of the leading end of the conjugate pad.

In some of these embodiments, a lower surface of the distal end of the guide membrane is in contact with an upper surface of the front end of the sample pad; or

An upper surface of a tip of the guide film is in contact with a lower surface of a front end of the sample pad.

In some of these embodiments, a lower surface of the distal end of the sample limiting membrane is in contact with an upper surface of the leading end of the guide membrane; or

An upper surface of a tip end of the sample limiting membrane is in contact with a lower surface of a leading end of the guide membrane.

In some of these embodiments, with the end of the absorbent pad on the upper surface of the substrate and the front end of the absorbent pad on the lower surface of the substrate:

the length of the absorbent pad on the upper surface of the base material is greater than that of the absorbent pad on the lower surface of the base material; or

The length of the absorbent pad on the upper surface of the base material is equal to that of the absorbent pad on the lower surface of the base material; or

The length of the absorbent pad on the upper surface of the substrate is smaller than that of the absorbent pad on the lower surface of the substrate.

In some of these embodiments, where the front end of the chromatographic membrane is located on the upper surface of the substrate and the end of the chromatographic membrane is located on the lower surface of the substrate:

the length of the chromatographic membrane positioned on the upper surface of the substrate is greater than the length of the chromatographic membrane positioned on the lower surface of the substrate; or

The length of the chromatographic membrane positioned on the upper surface of the substrate is equal to the length of the chromatographic membrane positioned on the lower surface of the substrate; or

The length of the chromatographic membrane on the upper surface of the substrate is smaller than the length of the chromatographic membrane on the lower surface of the substrate.

In some of these embodiments, the inspection line and the quality control line are located on an upper surface of the substrate; or

The detection line is positioned on the upper surface of the substrate, and the quality control line is positioned on the lower surface of the substrate; or

The detection line and the quality control line are positioned on the lower surface of the substrate.

In some of these embodiments, the biochemical strip further comprises:

the biochemical test paper is arranged inside the transparent hollow tube, and the transparent hollow tube is arranged inside the test paper fixing part.

In some of these embodiments, one end of the transparent hollow tube is closed.

The utility model adopts the above technical scheme, compare with prior art, have following technological effect:

the utility model discloses a biochemical test paper tube, utilize first locating component and second locating component to fix a position the sample cell of putting into the solution chamber, make the sample to be detected in the sample cell mix under the encapsulated situation with the solution in the solution chamber, reduced the exposure time of the sample to be detected, reduce and infect the risk; the detection process is carried out in a totally-enclosed manner, and after the detection is finished, the biochemical test paper tube can be directly discarded as medical waste, so that the environment pollution is avoided, and the influence of high-hazard substances in the test tube on the life safety is prevented.

Drawings

FIG. 1 is a schematic view (one) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 2 is a top view (one) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 3 is a cross-sectional view (one) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 4 is a schematic view (one) of the interior of the solution chamber of the biochemical test paper tube according to the embodiment of the present application;

FIG. 5 is a schematic view (two) showing an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 6 is a plan view of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 7 is a cross-sectional view (II) showing an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 8 is a schematic view of the inside of a solution chamber of a biochemical test paper tube according to an embodiment of the present application (II);

FIG. 9 is a plan view (III) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 10 is a cross-sectional view (III) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 11 is a schematic view (III) of the interior of the solution chamber of the biochemical test paper tube according to the embodiment of the present application;

FIG. 12 is a sectional view (one) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 13 is a sectional view (II) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 14 is a sectional view (III) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 15 is a plan view (IV) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 16 is a cross-sectional view (IV) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 17 is a cross-sectional view (V) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIGS. 18A to 18C are sectional views (I) showing the state of use of a biochemical test paper tube according to an embodiment of the present application;

FIG. 19 is a sectional View (VI) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 20 is a sectional View (VII) of an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 21 is a sectional view (IV) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 22 is a schematic view (two) showing an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 23 is a sectional view (eight) showing an unclosed state of a biochemical test paper tube according to an embodiment of the present application;

FIG. 24 is a sectional view (V) showing a closed state of a biochemical test paper tube according to an embodiment of the present application;

FIGS. 25A to 25C are sectional views showing the state of use of the biochemical test paper tube according to the embodiment of the present application;

FIG. 26 is a schematic view of a biochemical test strip according to an embodiment of the present application;

FIG. 27 is a sectional view of a biochemical test strip according to an embodiment of the present application (II);

FIG. 28 is a schematic view of a biochemical test strip according to an embodiment of the present application (two);

FIG. 29 is a sectional view of a biochemical test strip according to an embodiment of the present application (II);

FIG. 30 is a schematic view (III) of a biochemical test strip according to an embodiment of the present application;

FIG. 31 is a sectional view of a biochemical test strip according to an embodiment of the present application (III);

FIG. 32 is a schematic view (IV) of a biochemical test strip according to an embodiment of the present application;

FIG. 33 is a sectional view (IV) of the biochemical test strip according to the embodiment of the present application;

FIG. 34 is a sectional view of a biochemical test strip according to an embodiment of the present application (V);

FIG. 35 is a cross-sectional view (one) of a transparent hollow tube according to an embodiment of the present application;

FIG. 36 is a cross-sectional view of a transparent hollow tube according to an embodiment of the present application (II);

wherein the reference numerals are: 100. a tube portion 100; 101. a solution chamber; 102. a test paper fixing member; 103. a first positioning member; 104. a second positioning member; 105. a third positioning member; 106. a piercing member; 107. a flow channel; 108. sealing the platform; 109. a sealing film; 110. a first fitting member;

200. a cover portion; 201. a cavity; 202. a sealing member; 203. a second fitting member; 204. a pressing member;

300. a connecting portion 300;

400. biochemical test paper; 401. a substrate; 402. a chromatographic membrane; 403. detecting lines; 404. a quality control line; 405. a water absorbent pad; 406. a bonding pad; 407. a guide film; 408. a sample pad; 409. a sample limiting membrane; 410. a transparent protective film;

500. a sample tube;

600. a transparent hollow tube.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

It should be noted that, in the present invention, the embodiments and features of the embodiments may be combined with each other without conflict.

The present invention will be further described with reference to the accompanying drawings and specific embodiments, but the present invention is not limited thereto.

Example 1

As shown in FIGS. 1 to 4, a biochemical test paper tube comprises a tube part 100 and a cap part 200, wherein the cap part 200 is used for sealing the tube part 100.

The tube portion 100 includes a solution chamber 101, a test strip fixing member 102, a first positioning member 103, and a plurality of second positioning members 104.

The axial direction of the solution chamber 101 is collinear or parallel with the axial direction of the tube portion 100, and the solution chamber 101 is used for placing a solution such as a reaction solution. The axial direction of the test paper fixing part 102 is parallel to the axial direction of the solution chamber 101, and the test paper fixing part 102 is used for placing the biochemical test paper 400.

The first positioning member 103 is a central positioning member, and is disposed at the middle of the bottom of the solution chamber 101 for placing a piercing member (not shown).

A plurality of second positioning members 104 are disposed on the upper portion of the first positioning member 103 and surround to form a virtual first chamber for guiding and positioning the sidewall of a sample tube (not shown) placed in the solution chamber 101.

The virtual first chamber is a chamber formed by arranging virtual walls in a space formed by a plurality of second positioning members 104 to present an opening on one side.

Further, in order to improve the guiding and positioning of the sample tube, the tube part 100 further comprises a plurality of third positioning members 105. The third positioning members 105 are disposed at the bottom of the solution chamber 101, and are not in contact with the first positioning members 103 and the second positioning members 104, and the height of the third positioning members is higher than the height of the first positioning members 103, and the top ends of the third positioning members are located below the bottom ends of the second positioning members 104, so as to guide and position-limit the sidewall of the bottom of a sample tube (not shown in the figure) placed in the solution chamber 101.

The top end of the third positioning member 105 is a slope for fitting the sidewall of the bottom of the sample tube.

In some of the embodiments, the plurality of second positioning members 104 is spaced apart from the plurality of third positioning members 105 when the tube portion 100 is viewed from a top view, that is, a third positioning member 105 is disposed between two adjacent second positioning members 104.

In some embodiments, when the tube 100 is viewed from a top view, the second positioning members 104 and the third positioning members 105 are irregularly arranged, for example, the third positioning member 105 may not be arranged between two adjacent second positioning members 104, at least one third positioning member 105 may be arranged, or the third positioning member 105 may be arranged directly below the second positioning members 104.

The lid section 200 includes a cavity 201, and the cavity 201 is formed by an inner surface of the lid section 200 being outwardly convex.

Wherein, the longitudinal section of the cavity 201 is trapezoid, circular arc or triangle.

The biochemical test paper tube further includes a connection portion 300, and the connection portion 300 is connected to the tube portion 100 and the cap portion 200, respectively.

Wherein, the tube part 100, the cap part 200 and the connecting part 300 may be integrally connected, i.e. the biochemical test paper tube is a one-piece test tube. In this case, the connection part 300 may be a connection bar.

Wherein, tube portion 100, cap portion 200 and connecting portion 300 can be split type connection, and the biochemical test paper tube is split type test tube promptly. In this case, the connection part 300 may be a locking ring, a locking bar. Specifically, the tube portion 100 and the cap portion 200 are each provided with a locking hole that are fitted to each other, and in the case where the cap portion 200 closes the tube portion 100, a locking bar is passed through the locking holes of the tube portion 100 and the cap portion 200 in order to lock the cap portion 200 and the tube portion 100.

When the lid 200 closes the tube 100, the lid 200 is fitted to the tube 100 with interference, and the solution in the tube 100 is held in a vacuum environment of 3kg for at least 10 minutes without leaking.

Example 2

As shown in FIGS. 5 to 8, a biochemical test paper tube comprises a tube part 100 and a cap part 200, wherein the cap part 200 is used for sealing the tube part 100.

The tube portion 100 includes a solution chamber 101, a test strip fixing member 102, a plurality of first positioning members 103, a plurality of second positioning members 104, and a plurality of third positioning members 105.

The structure and connection relationship of the solution chamber 101, the test paper fixing member 102, the second positioning members 104, and the third positioning members 105 are substantially the same as those in embodiment 1, and are not described herein again.

The first positioning members 103 are side positioning members disposed at the bottom of the solution chamber 101, and are respectively connected to the bottom wall and the side wall of the solution chamber 101, and surround to form a virtual second chamber for placing a piercing member (not shown).

In some of these embodiments, the axis of the virtual second chamber is taken as a center line, around which the plurality of first positioning members 103 are disposed, and around which the plurality of third positioning members 105 are disposed; the first positioning members 103 are spaced apart from the third positioning members 105, i.e., a third positioning member 105 is disposed between two adjacent first positioning members 103.

In some of these embodiments, the axis of the virtual second chamber is taken as a center line, around which the plurality of first positioning members 103 are disposed, and around which the plurality of third positioning members 105 are disposed; the third positioning members 105 may not be provided between two adjacent first positioning members 103, or at least one third positioning member 105 may be provided, that is, a plurality of first positioning members 103 and a plurality of third positioning members 105 are irregularly provided.

In some of these embodiments, the second positioning member 104 may block the first positioning members 103 when the tube portion 100 is viewed from a top view, i.e., one second positioning member 104 is disposed directly above each first positioning member 103; the second positioning members 104 may not block the first positioning members 103, that is, one second positioning member 104 may be provided obliquely above each first positioning member 103; alternatively, at least one first positioning member 103 is provided between two adjacent second positioning members 104 when the tube portion 100 is viewed in a plan view.

The number of the first positioning members 103, the number of the second positioning members 104, and the number of the third positioning members 105 may be equal or different.

The virtual second chamber is a chamber formed by arranging virtual walls in a space formed by the first positioning members 103 to present an opening on one side.

Wherein the axis of the first chamber is coaxial or parallel to the axis of the second chamber for aligning the center (or center) of the bottom of the sample tube 500 with the piercing member 106, i.e., the axis of the sample tube 500 is substantially collinear with the axis of the piercing member 106, such that the piercing member 106 pierces the sample tube 500.

Where the axis of the first chamber is parallel to the axis of the second chamber, the horizontal distance between the axis of the first chamber and the axis of the second chamber is less than 3 mm.

The structure and connection relationship of the cover 200 and the connection 300 are substantially the same as those of the embodiment, and are not described again.

Example 3

This example is a combination of examples 1 to 2.

As shown in FIGS. 9 to 11, a biochemical test paper tube comprises a tube part 100 and a cap part 200, wherein the cap part 200 is used for sealing the tube part 100.

The first positioning member 103 includes a center positioning member and a plurality of side positioning members, the center positioning member is disposed in the middle of the bottom of the solution chamber 101, the plurality of side positioning members are disposed around the center positioning member with the center positioning member as a center, and the center positioning member and the plurality of side positioning members are not in contact with each other.

In this embodiment, the bottom of the puncturing element is engaged with the central positioning element, and the side surfaces of the puncturing element are engaged with the side positioning elements, thereby effectively fixing the puncturing element.

Example 4

The present embodiment is an extended embodiment of embodiments 1 to 3, and the present embodiment specifically describes the structure of the nozzle of the tube portion 100 and the structure of the cap portion 200.

The cap 200 further includes a stopper member which is a skirt having an outer diameter equal to the outer diameter of the nozzle of the tube 100 (as shown in fig. 12), or an outer diameter smaller than the outer diameter of the nozzle of the tube 100 and larger than the inner diameter of the nozzle of the tube 100 (as shown in fig. 13).

With the above design, it is possible to facilitate separation of the cap portion 200 from the tube portion 100.

Example 5

The present embodiment is an extended embodiment of embodiments 1 to 3, and the present embodiment is different from embodiments 1 to 3 in that: the particular design of the orifice shape of the tube portion 100.

As shown in FIG. 14, the biochemical test paper tube further comprises an opening prevention part provided at the top of the tube part 100, i.e., the mouth of the tube part 100. Specifically, the nozzle of the tube 100 is designed to be tamper-proof, i.e., the opening preventing member is a counter bore, i.e., the cross section of the nozzle is stepped, and the limiting member (skirt) of the cap 200 is embedded or sunk into the counter bore of the nozzle. The upper surface of the skirt and the upper surface of the top of the pipe orifice are positioned on the same horizontal plane or the upper surface of the skirt is positioned below the upper surface of the pipe orifice; the outer edge of the skirt is in contact with the inner edge of the top of the spout, i.e. the outer diameter of the skirt is equal to the inner diameter of the top of the spout.

In some of the embodiments, the opening prevention member further includes a chamfered portion provided at an outer wall of the stopper member of the lid portion 200, i.e., an outer edge of the skirt of the lid portion 200 is provided with a chamfer having a lower outer diameter greater than an upper outer diameter of the chamfer.

With the above design, when the lid 200 closes the tube portion 100, the lid 200 cannot be separated from the tube portion 100 without dismantling violence, i.e., a totally enclosed design is formed, and after the detection is completed, there is no need to worry about the overflow of the solution in the tube portion 100, thereby avoiding the problems of environmental pollution and the like.

Example 6

This embodiment is an extended embodiment of embodiments 1 to 3, and is different from embodiments 1 to 2 in that: piercing member 106 of tube portion 100.

As shown in fig. 15 to 16, the tube portion 100 further includes a piercing member 106, and the piercing member 106 and the tube portion 100 are designed in a split manner. The piercing member 106 is mounted in the second chamber, such as by adhesive bonding or the like.

In some of these embodiments, the puncturing member 106 is a bayonet connection with a central locating member in the first locating member 103.

In some of these embodiments, as shown in FIG. 17, the piercing member 106 is of one-piece design with the tube portion 100, i.e., the piercing member 106 is of one-piece design with the first positioning member 103.

The piercing member 106 may be made of a hard plastic material, or may be made of a metal material.

In some embodiments, the side positioning members of the plurality of first positioning members 103 are circumferentially disposed outside the puncture member 106 with the puncture member 106 as a center. Specifically, the included angle formed by two adjacent side positioning parts is 360 degrees/n, wherein n is the number of the side positioning parts.

Similarly, when a sample tube (not shown) is inserted into the second chamber, the second positioning members 104 are disposed axially outside the sample tube with the sample tube as a center. Specifically, the angle formed by two adjacent second positioning members 104 is 360 °/n, where n is the number of second positioning members 104.

Similarly, in the case where a sample tube (not shown) is inserted into the second chamber, a plurality of third positioning members 105 are axially disposed outside the sample tube centering on the sample tube. Specifically, the angle formed by two adjacent third positioning members 105 is 360 °/n, where n is the number of third positioning members 105.

The inner surface of each second locating member 104 that contacts the sample tube mates with the sidewall of the sample tube. That is, the inner surfaces of the plurality of second positioning members 104 form a guide rail having a guide function and a stopper function. Under the action of the track, the sample tube moves downwards.

The inner surface of each third positioning member 105 that contacts the sample tube mates with the sidewall of the bottom of the sample tube. That is, the inner surfaces of the third positioning members 105 form a stopper rail, and the sample tube is fixed in the virtual second chamber by the rail.

In addition, in order to improve the efficiency of gas-liquid exchange between the sample tube and the solution chamber 101, the piercing member 106 further includes a flow path 107 for allowing sufficient gas-liquid exchange between the sample tube and the solution chamber 101. In the case where the sample tube is punctured by the puncturing member 106, one end of the flow channel 107 is located inside the sample tube, and the other end of the flow channel 107 is located inside the solution chamber 101.

Specifically, in the case that the bottom of the sample tube is punctured by the tip and/or blade of the puncturing member 106, the bottom end of the sample tube is cut by the tip and/or blade of the puncturing member 106 to form at least one gap, and the gap extends from the bottom end of the sample tube to the inner wall of the sample tube; in the case where the tip and/or blade of the piercing member 106 is inserted into the sample tube, a gap exists between the flow channel 107 and the ruptured inner wall of the sample tube, so that the internal solution of the sample tube flows into the solution chamber 101 from the gap, the flow channel 107.

The flow channel 107 may be disposed at the bottom of the puncturing member 106, or may be disposed on the puncturing member 106.

Wherein the flow channel 107 is provided in a recessed portion between the pointed end of the piercing member 106 and/or the raised portion of the blade.

Specifically, in the case where the top of the piercing member 106 is a blade portion, the flow channel 107 may be provided on the blade portion, or may be provided on the blade wall on the adjacent two sides of the blade portion.

Further, in order to facilitate the bottom of the sample tube to be punctured by the puncturing member 106, the bottom surface of the sample tube is planar.

The method of use of this example is as follows: as shown in fig. 18A to 18C, a sample to be tested is placed in the sample tube 500 and sealed; exposing the solution cavity 101, and placing the sample tube 500 into the solution cavity 101; under the guiding and limiting effects of the second positioning components 104 and the third positioning components 105, the bottom of the sample tube 500 is aligned to the puncturing component 106 arranged at the bottom of the solution cavity 101 and is punctured by the puncturing component 106; under the action of the flow channel 107, the reaction solution in the solution cavity 101 is mixed with the sample to be detected in the sample tube 500 to obtain a mixed solution; closing the tube portion 100 with the cap portion 200; after reacting for a certain time, inclining the tube part 100 to make the sample solution receiving end of the biochemical test paper arranged in the test paper fixing part 102 contact the mixed solution, and the mixed solution performs chromatography on the biochemical test paper; the detection result can be obtained by observing the biochemical test paper; after the detection result is observed, the biochemical test paper tube can be directly treated as medical waste without worrying about the leakage of substances in the biochemical test paper tube.

Example 7

This embodiment is an extended embodiment of embodiments 1 to 3, and is different from embodiments 1 to 4 in that: the tube 100 and the cap 200 are designed to be fitted together in a sealing manner.

As shown in FIGS. 19 to 21, the biochemical test paper tube comprises a tube part 100, a cap part 200 and a connecting part 300, wherein the tube part 100 and the cap part 200 are connected by the connecting part 300, and the cap part 200 is used for sealing the tube part 100.

The connection relationship and structure of the connection portion 300 are substantially the same as those in embodiments 1 to 3, and are not described herein again.

The tube portion 100 includes a solution chamber 101, a test strip fixing member 102, a first positioning member 103, a plurality of second positioning members 104, a plurality of third positioning members 105, a puncturing member 106, a flow channel 107, and a first engaging member 110, wherein the connection relationship and structure of the solution chamber 101, the test strip fixing member 102, the first positioning member 103, the plurality of second positioning members 104, the puncturing member 106, and the flow channel 107 are substantially the same as those of embodiments 1 to 3, and are not described again.

The first fitting parts 110 are provided on the inner wall of the top of the pipe portion 100 at intervals in the axial direction of the pipe portion 100.

The lid section 200 includes a cavity 201, a pressing member 204, a sealing member 202, and a second fitting member 203. The connection relationship and structure of the cavity 201 and the pressing member 204 are substantially the same as those in embodiment 3, and are not described herein again.

The sealing member 202 and the second fitting member 203 are provided at intervals in the axial direction of the lid portion 200. When the lid 200 closes the tube 100, the sealing member 202 is positioned below the lid 200, and the second fitting member 203 is positioned above the sealing member 202.

When the lid 200 closes the tube 100, the sealing member 202 seals the tube 100, and the first fitting member 110 is fitted to the second fitting member 203, so that the lid 200 and the tube 100 are tightly connected to each other, thereby improving the opening prevention performance of the biochemical test paper tube.

In some of these embodiments, the sealing member 202 is an annular protrusion having an outer diameter equal to the inner diameter of the top of the tube portion 100.

In some of these embodiments, the first fitting part 110 is an annular projection having an outer diameter larger than an inner diameter of the top of the tube part 100; the second fitting part 203 is an annular groove which is tightly fitted with the first fitting part 110.

In the present embodiment, the cap 200 is interference-fitted to the tube 100, that is, the sealing member 202 is interference-fitted to the inner wall of the nozzle of the tube 100, the first fitting member 110 is fitted to the second fitting member 203 (equivalent to interference fitting), and the sealing member 202 is fitted to the first fitting member 110 (equivalent to interference fitting), so that the solution in the tube 100 is maintained in a vacuum of 3kg for at least 10 minutes without leaking when the cap 200 closes the tube 100.

Through the sealing member, first gomphosis part and the second gomphosis part of this embodiment, further improve the inseparable degree of being connected between cap and the pipe portion, greatly improved the resistance with cap and pipe portion separation, effectively prevent the intraductal solution of biochemical test paper and leak, avoid the polluted environment, prevent to endanger life health.

Example 8

This embodiment is an extended embodiment of embodiment 7, and is different from embodiments 1 to 3 in that: the sealing design of the tube portion 100.

The connection relationship and structure between the cover 200 and the connection 300 are substantially the same as those in embodiments 1 to 3, and are not described herein again.

The tube portion 100 includes a solution chamber 101, a test strip fixing member 102, a first positioning member 103, a plurality of second positioning members 104, a plurality of third positioning members 105, a puncturing member 106, a flow channel 107, a sealing land 108, a sealing film 109, and a first engaging member 110, wherein the connection relationship and structure of the solution chamber 101, the test strip fixing member 102, the first positioning member 103, the plurality of second positioning members 104, the plurality of third positioning members 105, the puncturing member 106, the flow channel 107, and the first engaging member 110 are substantially the same as those of embodiment 7, and will not be described herein again.

A sealing platform 108 is arranged on the end face of the top of the solution chamber 101, and the sealing platform 108 is arranged around the solution chamber 101.

Wherein the width of the sealing platform 108 is at least 1 mm; a certain horizontal distance is formed between the outer wall of the sealing platform 108 and the inner wall of the pipe part 100, and the horizontal distance is at least 0.5 mm; the bottom wall of the sealing platform 108 is at a vertical distance from the inner wall of the tube portion 100, and is at least 0.5 mm.

Specifically, the sealing land 108 forms a channel, or isthmus, with the inner wall of the tubular portion 100.

In the case that the lid part 200 closes the tube part 100, the top of the sealing platform 108 is not in contact with the bottom of the lid part 200, i.e. there is a certain vertical distance between the top of the sealing platform 108 and the bottom of the lid part 200, and at least 1 mm; the outer wall of the sealing land 108 is at a horizontal distance from the inner wall of the cover part 200 and is at least 0.5 mm.

The sealing film 109 is connected to the sealing platform 108 to seal the solution chamber 101 for preventing the solution preset inside the solution chamber 101 from overflowing.

When leaving a factory, a reaction solution can be preset in the solution cavity 101, and then the solution cavity 101 is sealed by using a sealing film 109; or after leaving the factory, after the tester takes the biochemical test paper tube, the reaction solution is prepared and placed in the solution cavity 101, and finally the solution cavity 101 is sealed by the sealing film 109, and the biochemical test paper tube is stored for later use.

Furthermore, in some embodiments, the sealing film 109 may also seal the test strip holding member 102. Specifically, the test paper fixing member 102 may be sealed before the biochemical test paper is placed on the test paper fixing member 102, i.e., to prevent foreign substances from entering the test paper fixing member 102; it is also possible to seal the reagent fixing member 102 when the biochemical reagent is placed in the reagent fixing member 102, i.e., to keep the biochemical reagent from foreign substances before use.

The sealing film 109 may be an aluminum foil film, a plastic film, or a non-setting adhesive film. The sealing film 109 may be assembled with the biochemical test paper tube during the production process, or may be assembled with the biochemical test paper tube before the transportation process, or may be assembled with the biochemical test paper tube before the storage process.

Further, the shape of the sealing film 109 is substantially the same as that of the opening at the top of the solution chamber 101, i.e., the area of the cross section of the sealing film 109 is slightly larger than that of the opening at the top of the solution chamber 101. In this case, the sealing film 109 needs to be broken by an auxiliary tool, such as a tool having a sharp end, a blunt end, and a blade.

Further, the shape of the sealing film 109 is different from the shape of the orifice at the top of the solution chamber 101, i.e., the sealing film 109 includes a sealing portion that seals the solution chamber 101 and an extension portion that is provided at the side of the sealing portion and is integrally formed with the sealing portion. Wherein the shape of the sealing portion is substantially the same as the shape of the orifice at the top of the solution chamber 101. The extension portion has a bar shape for separating the sealing portion from the solution chamber 101.

The method of use of this example is as follows: breaking or removing the sealing film 109, placing the sample tube 500 loaded with the sample to be detected into the solution chamber 101, and under the guiding and limiting action of the second positioning components 104, aligning the bottom of the sample tube 500 with the puncture component 106 arranged at the bottom of the solution chamber 101 and puncturing the puncture component 106; under the action of the flow channel 107, the reaction solution in the solution cavity 101 is mixed with the sample to be detected in the sample tube 500 to obtain a mixed solution; closing the tube portion 100 with the cap portion 200; after reacting for a certain time, inclining the tube part 100 to make the sample solution receiving end of the biochemical test paper arranged in the test paper fixing part 102 contact the mixed solution, and the mixed solution performs chromatography on the biochemical test paper; the detection result can be obtained by observing the biochemical test paper; after the detection result is observed, the biochemical test paper tube can be directly treated as medical waste without worrying about the leakage of substances in the biochemical test paper tube.

Example 9

This embodiment is an extended embodiment of embodiment 8, and the difference between this embodiment and embodiment 8 is: the lid section 200 further includes a pressing member 204.

As shown in FIGS. 22 to 24, the biochemical test paper tube comprises a tube part 100, a cap part 200 and a connecting part 300, wherein the tube part 100 and the cap part 200 are connected by the connecting part 300, and the cap part 200 is used for sealing the tube part 100.

The structure and connection relationship of the tube portion 100 and the connection portion 300 are substantially the same as those of embodiment 8, and will not be described again.

The lid portion 200 includes a cavity 201, a sealing member 202, a second engaging member 203, and a pressing member 204, wherein the connection relationship and structure of the cavity 201, the sealing member 202, and the second engaging member 203 are substantially the same as those of embodiment 8, and are not described herein again.

The pressing member 204 is disposed inside the cavity 201. Wherein, the pressing member 204 is a strip, and is used for aligning the pressing member 204 with the top of the sample tube 500 under the condition that the cap portion 200 closes the tube portion 100, and applying a substantially vertical downward pressure at the position where the pressing member 204 contacts the sample tube 500, so that the sample tube 500 is rapidly punctured by the puncturing member 106.

Specifically, in the process of closing the tube part 100 by the cap part 200, the pressing part 204 contacts the top of the sample tube 500 and pushes the sample tube 500 to be inserted into the solution chamber 101 downward in the guiding of the plurality of second positioning parts 104 in cooperation with the side wall of the sample tube 500, the bottom of the sample tube 500 is punctured by the tip and/or blade of the puncturing part 106, and the tip and/or blade of the puncturing part 106 is inserted into the sample tube 500 by at least 1 mm.

The pressing member 204 can increase the pressure intensity per unit area and the speed of puncturing the sample tube 500 by the puncturing member 106 when the same pressure is applied.

The method of use of this example is as follows: as shown in fig. 25A to 25C, the sealing film 109 is broken or removed, and a sample tube 500 loaded with a sample to be tested is placed inside the solution chamber 101; the cap part 200 is used for closing the tube part 100, and under the guiding and limiting action of the plurality of second positioning parts 104, the bottom of the sample tube 500 is aligned with the puncture part 106 arranged at the bottom of the solution cavity 101; under the pressing action of the pressing component 204, the bottom of the sample tube 500 is punctured by the puncturing component 106; under the action of the flow channel 107, the reaction solution in the solution cavity 101 is mixed with the sample to be detected in the sample tube 500 to obtain a mixed solution; closing the tube portion 100 with the cap portion 200; after reacting for a certain time, inclining the tube part 100 to make the sample solution receiving end of the biochemical test paper arranged in the test paper fixing part 102 contact the mixed solution, and the mixed solution performs chromatography on the biochemical test paper; the detection result can be obtained by observing the biochemical test paper; after the detection result is observed, the biochemical test paper tube can be directly treated as medical waste without worrying about the leakage of substances in the biochemical test paper tube.

Example 10

This example relates to a biochemical test paper placed in the biochemical test paper tube of examples 1-9.

In this example, a biochemical test strip is exemplified as an immunochromatographic test strip.

As shown in fig. 26 to 27, a biochemical test paper 400 includes a substrate 401, a chromatographic membrane 402, a water absorption pad 405, a binding pad 406 and a guiding membrane 407, wherein the guiding membrane 407, the binding pad 406, the chromatographic membrane 402 and the water absorption pad 405 are sequentially disposed on the substrate 401.

Wherein, the length of the biochemical test paper 400 is greater than the height of the test paper fixing part 102. In general, the difference between the length of the biochemical test strip 400 and the height of the test strip fixing member 102 is 1mm to 5mm, and preferably 2mm to 3 mm.

In the case where the biochemical test paper 400 is disposed on the test paper fixing member 102, the sample solution receiving end of the biochemical test paper 400 extends upward and has a height greater than the orifice of the tube portion 100.

Further, in the case where the cap 200 closes the tube portion 110, the sample solution receiving end of the biochemical test paper 400 extends upward and protrudes into the cavity 201 of the cap 200.

The substrate 401 is made of plastic, such as a non-setting adhesive.

The guide film 407 is disposed on the upper surface of the substrate 401, i.e., the lower surface of the guide film 407 and the upper surface of the substrate 401 are connected, e.g., bonded. The end of the guide film 407 contacts the front end of the conjugate pad 406, and the guide film 407 transmits the solution to the conjugate pad 406.

The upper surface of the tip of the guide film 407 contacts the lower surface of the front end of the bonding pad 406, or the lower surface of the tip of the guide film 407 contacts the upper surface of the front end of the bonding pad 406.

Wherein the guide film 407 is made of a cellulose film.

Wherein the thickness of the guide film 407 is less than 0.15 mm.

The bond pads 406 are disposed on the upper surface of the substrate 401, i.e., the lower surface of the bond pads 406 is attached, e.g., adhered, to the upper surface of the substrate 401. The end of the conjugate pad 406 contacts the front end of the chromatographic carrier 402 and the conjugate pad 406 delivers the solution to the chromatographic carrier 402. Specifically, the upper surface of the end of the conjugate pad 406 is in contact with the lower surface of the front end of the chromatographic carrier 402, or the lower surface of the end of the conjugate pad 406 is in contact with the upper surface of the front end of the chromatographic carrier 402.

Wherein the bonding pad 406 is a gold pad.

The bonding pad 406 is made of glass fiber, polyester film, cellulose filter paper, nonwoven fabric, or the like.

Wherein the solution chromatography speed of the guide membrane 407 is lower than that of the conjugate pad 406.

The chromatographic carrier 402 is disposed on at least the upper surface of the substrate 401, i.e., the lower surface of the chromatographic carrier 402 is attached, e.g., adhered, to the upper surface of the substrate 401. The end of the chromatographic carrier 402 is in contact with the end of the absorbent pad 405, and the chromatographic carrier 402 transfers the solution to the absorbent pad 405.

The chromatographic membrane 402 is further provided with a detection line 403 and a quality control line 404, which are sequentially arranged along the front end to the tail end of the chromatographic membrane 402.

Among them, the chromatographic carrier 402 is made of a nitrocellulose membrane.

The absorbent pad 405 is disposed on at least the lower surface of the substrate 401, i.e., the upper surface of the absorbent pad 405 is connected to, e.g., adhered to, the lower surface of the substrate 401. The end of the absorbent pad 405 contacts the end of the chromatographic carrier 402.

Wherein the absorbent pad 405 is absorbent paper.

Wherein the end of the chromatographic carrier 402 and the end of the absorbent pad 405 are contacted with each other at the end of the substrate 401 and solution transfer is performed.

In the first embodiment of this example, the end of the chromatographic carrier 402 is beyond the end of the substrate 401 by a certain distance, the end of the absorbent pad 405 is beyond the end of the substrate 401 by a certain distance, and the end of the chromatographic carrier 402 and the end of the absorbent pad 405 are in contact and perform solution transfer, that is, the lower surface of the end of the chromatographic carrier 402 and the upper surface of the end of the absorbent pad 405 are in contact and perform solution transfer. In this embodiment, the chromatographic carrier 402, the substrate 401 and the absorbent pad 405 form a sandwich structure.

In the second embodiment of this embodiment, the chromatographic carrier 402 is also disposed on the lower surface of the substrate 401, i.e., the end of the chromatographic carrier 402 is bent downward at the end of the substrate 401. Specifically, the upper surface of the end of the chromatographic carrier 402 and the upper surface of the end of the absorbent pad 405 are in contact and solution transfer is performed, or the lower surface of the end of the chromatographic carrier 402 and the lower surface of the end of the absorbent pad 405 are in contact and solution transfer is performed.

In this embodiment, the length of the chromatographic carrier 402 located on the upper surface of the substrate 401 is greater than the length of the chromatographic carrier 402 located on the lower surface of the substrate 401; alternatively, the length of the chromatographic carrier 402 located on the upper surface of the substrate 401 is equal to the length of the chromatographic carrier 402 located on the lower surface of the substrate 401; alternatively, the length of the chromatographic carrier 402 located on the upper surface of the substrate 401 is shorter than the length of the chromatographic carrier 402 located on the lower surface of the substrate 401.

Preferably, the length of the chromatographic carrier 402 located on the upper surface of the substrate 401 is longer than the length of the chromatographic carrier 402 located on the lower surface of the substrate 401

In the third embodiment of this embodiment, the absorbent pad 405 is also disposed on the upper surface of the base material 401, i.e., the end of the absorbent pad 405 is bent upward at the end of the base material 401. Specifically, the upper surface of the end of the absorbent pad 405 and the upper surface of the end of the chromatographic carrier 402 are in contact and solution transfer is performed, or the lower surface of the end of the absorbent pad 405 and the lower surface of the end of the chromatographic carrier 402 are in contact and solution transfer is performed.

In this embodiment, the length of the absorbent pad 405 on the upper surface of the substrate 401 is greater than the length of the absorbent pad 405 on the lower surface of the substrate 401; alternatively, the length of the absorbent pad 405 on the upper surface of the substrate 401 is equal to the length of the absorbent pad 405 on the lower surface of the substrate 401; alternatively, the length of the absorbent pad 405 on the upper surface of the substrate 401 is less than the length of the absorbent pad 405 on the lower surface of the substrate 401.

Preferably, the length of the absorbent pad 405 on the upper surface of the substrate 401 is less than the length of the absorbent pad 405 on the lower surface of the substrate 401.

In order to ensure that the end of the chromatographic carrier 402 is in contact with the end of the absorbent pad 405, a thin film is provided between the end of the chromatographic carrier 402 and the end of the absorbent pad 405. The membrane covers the chromatographic carrier 402 and the absorbent pad 405 so that the chromatographic carrier 402 and the absorbent pad 405 are in contact.

In this embodiment, the length of the biochemical test strip 400 is 2cm to 4cm, preferably 2.8cm, 3.0cm, 3.2cm, and 3.5 cm.

The method of use of this example is as follows: placing the biochemical test paper 400 into the test paper fixing part 102 of the biochemical test paper tube, and enabling the sample solution receiving end of the biochemical test paper 400 to be arranged upwards (namely, a guide film 407); breaking or removing the sealing film 109, placing the sample tube 500 loaded with the sample to be detected into the solution chamber 101, and under the guiding and limiting action of the second positioning components 104, aligning the bottom of the sample tube 500 with the puncture component 106 arranged at the bottom of the solution chamber 101 and puncturing the puncture component 106; under the action of the flow channel 107, the reaction solution in the solution cavity 101 is mixed with the sample to be detected in the sample tube 500 to obtain a mixed solution; closing the tube portion 100 with the cap portion 200; after reacting for a certain time, inclining the tube part 100 to make the guide film 407 of the biochemical test paper 400 arranged in the test paper fixing part 102 contact the mixed liquid, and the mixed liquid performs chromatography on the biochemical test paper 400; the detection result can be obtained by observing the biochemical test paper 400; after the detection result is observed, the biochemical test paper tube can be directly treated as medical waste without worrying about the leakage of substances in the biochemical test paper tube.

Example 11

As shown in fig. 28 to 29, a biochemical test strip 400 includes a substrate 401, a chromatographic membrane 402, a water absorption pad 405, a binding pad 406, a guiding membrane 407 and a sample pad 408, wherein the sample pad 408, the guiding membrane 407, the binding pad 406, the chromatographic membrane 402 and the water absorption pad 405 are disposed on the substrate 401.

The connection relationship, structure and composition of the substrate 401, the chromatographic membrane 402, the absorbent pad 405 and the conjugate pad 406 are substantially the same as those in embodiment 1, and are not described herein again.

Sample pad 408 is disposed on the upper surface of substrate 401, i.e., the lower surface of sample pad 408 is attached, e.g., bonded, to the upper surface of substrate 401.

The sample pad 408 is made of glass fiber, polyester film, cellulose filter paper, nonwoven fabric, or the like.

In the first embodiment of this embodiment, the end of the sample pad 408 is in contact with the front end of the guide film 407, and the sample pad 408 transfers the solution to the guide film 407. Specifically, the upper surface of the tip of the sample pad 408 is in contact with the lower surface of the leading end of the guide film 407, or the lower surface of the tip of the sample pad 408 is in contact with the upper surface of the leading end of the guide film 407.

In the second embodiment of this embodiment, the tip of the sample pad 408 is in contact with the end of the guide film 407, and the guide film 407 transmits the solution to the sample pad 408. Specifically, the upper surface of the tip of the guide film 407 contacts the lower surface of the front end of the sample pad 408, or the lower surface of the tip of the guide film 407 contacts the upper surface of the front end of the sample pad 408.

The end of the sample pad 408 contacts the front end of the conjugate pad 406 and the sample pad 408 delivers the solution to the conjugate pad 406. Specifically, the upper surface of the distal end of the sample pad 408 is in contact with the lower surface of the front end of the conjugate pad 406, or the lower surface of the distal end of the sample pad 408 is in contact with the upper surface of the front end of the conjugate pad 406.

In the third embodiment of this embodiment, as shown in fig. 13 to 14, the immunochromatographic test strip includes two guide films 407 disposed on the front and rear sides of the sample pad 408, respectively, i.e., the end of the first guide film 407 contacts the front end of the sample pad 408, and the first guide film 407 transmits a solution to the sample pad 408. Specifically, the upper surface of the tip of the first guide film 407 contacts the lower surface of the front end of the sample pad 408, or the lower surface of the tip of the first guide film 407 contacts the upper surface of the front end of the sample pad 408.

The end of the sample pad 408 is in contact with the second guide film 407, and the sample pad 408 transfers the solution to the second guide film 407. The upper surface of the tip of the sample pad 408 is in contact with the lower surface of the leading end of the second guide film 407, or the lower surface of the tip of the sample pad 408 is in contact with the upper surface of the leading end of the second guide film 407.

Wherein, in the case where there is only one guide film 407, the guide film 407 may be a first guide film; in the case where the number of the guide films 407 is two, the guide film 407 close to the chromatographic carrier 402 may be a first guide film, and the guide film 407 distant from the chromatographic carrier 402 may be a second guide film.

In this embodiment, the solution chromatography speed of the sample pad 408 is greater than that of the guide membrane 407.

In this embodiment, the length of the biochemical test strip 400 is 2cm to 4cm, preferably 3.2cm and 3.5 cm.

The using method of this embodiment is basically the same as that of embodiment 5, and is not described herein again.

Example 12

As shown in fig. 30 to 31, a biochemical test strip 400 includes a substrate 401, a chromatographic membrane 402, a water absorption pad 405, a binding pad 406, a guiding membrane 407, and a sample limiting membrane 409, wherein the sample limiting membrane 409, the guiding membrane 407, the binding pad 406, the chromatographic membrane 402, and the water absorption pad 405 are sequentially disposed on the substrate 401.

The connection relationship, structure and composition of the base 401, the chromatographic membrane 402, the absorbent pad 405, the conjugate pad 406 and the guide membrane 407 are substantially the same as those of embodiment 5, and are not repeated herein.

The sample limiting film 409 is disposed on the upper surface of the substrate 401, i.e., the lower surface of the sample limiting film 409 is attached, e.g., bonded, to the upper surface of the substrate 401. The end of the sample limiting film 409 is in contact with the front end of the guide film 407, and the sample limiting film 409 transfers the solution to the guide film 407. Specifically, the upper surface of the tip of the sample limiting film 409 is in contact with the lower surface of the leading end of the guide film 407, or the lower surface of the tip of the sample limiting film 409 is in contact with the upper surface of the leading end of the guide film 407.

Wherein the liquid absorption saturation volume of the sample limiting film 409 is 2-20 mul, and the sample limiting film can absorb trace samples.

The sample limiting film 409 is made of glass fiber, polyester film, cellulose filter paper, or the like.

In this embodiment, the length of the biochemical test strip 400 is 2cm to 4cm, preferably 3.3cm, 3.5cm, and 3.7 cm.

Example 13

As shown in fig. 32 to 33, a biochemical test strip 400 includes a substrate 401, a chromatographic membrane 402, a water absorption pad 405, a conjugate pad 406, a guide membrane 407, a sample pad 408, and a sample limiting membrane 409, wherein the sample limiting membrane 409, the guide membrane 407, the sample pad 408, the conjugate pad 406, the chromatographic membrane 402, and the water absorption pad 405 are disposed on the substrate 401.

The connection relationship, structure and composition of the substrate 401, the chromatographic membrane 402, the absorbent pad 405, the conjugate pad 406, the guide membrane 407 and the sample pad 408 are substantially the same as those of the second and third embodiments of example 6, and are not described herein again.

In this embodiment, the length of the biochemical test strip 400 is 2cm to 4cm, preferably 3.6cm and 3.8 cm.

Example 14

As shown in fig. 34, a biochemical test strip 400 includes a substrate 401, a chromatographic membrane 402, a water absorption pad 405, a conjugate pad 406, a guide membrane 407, and a transparent protective film 410, wherein the guide membrane 407, the conjugate pad 406, the chromatographic membrane 402, and the water absorption pad 405 are sequentially disposed on the substrate 401.

The connection relationship, structure and composition of the base 401, the chromatographic membrane 402, the absorbent pad 405, the conjugate pad 406 and the guide membrane 407 are substantially the same as those in embodiment 1, and are not described herein again.

The lower surface of the transparent protective film 410 covers at least the conjugate pad 406 and the chromatographic carrier 402.

In this embodiment, the transparent protective film 410 can prevent the binding pad 406 and the chromatographic carrier 402 from contacting with the exogenous aqueous mixture, thereby improving the accuracy of the detection result of the chromatographic strip.

The transparent protective film 410 may be applied to the biochemical test paper of examples 6 to 8.

Example 15

As shown in fig. 35, the biochemical test paper 400 further includes a transparent hollow tube 600, the transparent hollow tube 600 wraps the biochemical test paper 400 inside the transparent hollow tube 600, that is, the biochemical test paper 400 is disposed inside the transparent hollow tube 600.

The inner surface of the transparent hollow tube 600 is a hydrophobic surface.

The first end of the transparent hollow tube 600 is a closed end, and the second end thereof is an open end, which is provided to facilitate the movement of the biochemical test paper 400 from the open end to the inside of the transparent hollow tube 600.

In addition, the sample solution receiving end of the biochemical test strip 400 is located at the open end of the transparent hollow tube 600.

The transparent hollow tube 600 is made of a transparent material, such as plastic or thermoplastic resin, so as to facilitate observation of the detection or diagnosis result of the biochemical test paper 400.

In some of these embodiments, as shown in fig. 36, the width of the cross-section of the second end of the open end of the transparent hollow tube 600 is greater than the inner diameter of the cross-section of the first end of the open end. Preferably, the width of the cross-section of the open end of the transparent hollow tube 600 decreases from the second end of the open end to the first end of the open end.

The biochemical test paper 400 sleeved with the transparent hollow tube 600 is placed in the test paper fixing part 102 of the biochemical test paper tube, so that the biochemical test paper 400 is prevented from directly contacting with the inner surface of the test paper fixing part 102, and the surface tension of the inner surface of the test paper fixing part 102 is prevented from influencing the adsorption rate of the biochemical test paper 400.

The above description is only an example of the preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and those skilled in the art should be able to realize the equivalent alternatives and obvious variations of the present invention.

Claims

1. A biochemical test paper tube is characterized by comprising a tube part and a cover part;

the tube portion includes:

a solution chamber;

a first positioning member disposed at a bottom of the solution chamber;

2. The biochemical test paper tube according to claim 1, wherein the tube portion further comprises:

the third positioning parts are arranged at the bottom of the solution cavity and are not in contact with the first positioning part and the second positioning parts, the height of the third positioning parts is larger than that of the first positioning part, the top ends of the third positioning parts are positioned below the bottom ends of the second positioning parts, and each third positioning part is connected with the bottom wall of the solution cavity and the side wall of the solution cavity.

3. The biochemical test paper tube according to claim 1, wherein the first positioning member is disposed at a middle portion of the bottom of the solution chamber and connected to the bottom wall of the solution chamber; and/or

The first positioning parts are arranged at the bottom of the solution cavity and are connected with the bottom wall of the solution cavity and the side wall of the solution cavity.

4. The biochemical test paper tube according to claim 2, wherein the tube portion further comprises:

5. The biochemical test paper tube according to claim 4, further comprising:

6. The biochemical test paper tube of claim 5, wherein a plurality of the third positioning members are engaged with a sidewall of the sample tube when the sample tube is inserted into the solution chamber.

7. The biochemical test paper tube according to claim 5, wherein the cover portion comprises:

a pressing member provided inside a top surface of the lid portion;

8. The biochemical test paper tube according to claim 7, wherein in case that the bottom of the sample tube is punctured by the tip and/or the blade of the puncturing member, the bottom end of the sample tube is cut by the tip and/or the blade of the puncturing member to form at least one slit extending from the bottom end of the sample tube to the inner wall of the sample tube.

9. The biochemical test paper tube according to claim 7, wherein the puncture member further comprises:

10. The biochemical test paper tube according to claim 1, wherein the cover portion further comprises:

the cover portion further includes:

a sealing member provided on an outer wall of the lid section;

a second fitting member provided on an outer wall of the lid portion;

11. The biochemical test paper tube according to claim 1, wherein the cover portion further comprises:

a cavity formed by an inner surface of the cover portion bulging outward.

12. The biochemical test paper tube according to claim 1, further comprising:

13. The biochemical test paper tube according to claim 1, wherein the tube portion further comprises:

14. The biochemical test paper tube according to claim 13, wherein the tube portion further comprises:

15. The biochemical test paper tube according to claim 1, further comprising:

the biochemical test paper is arranged inside the test paper fixing part;

16. The biochemical test strip tube of claim 15, wherein the sample solution receiving end of the biochemical test strip extends upward and has a height greater than the orifice of the tube portion.