CN212514605U - Detection device - Google Patents

Abstract

The utility model discloses a detection device, including locking element, be configured to cavity intercommunication or the wall that can be with the difference, the locking element side is equipped with the location strip, is equipped with the through-hole on the locking element, and this through-hole can communicate different cavities. The utility model provides a locking element can adjust intercommunication and wall between the different cavitys betterly, easy operation, and it is convenient to adjust, and this locking element can also be used for pricking buffer reagent and hold device or closed layer, releases buffer reagent in to the cavity.

Description

Detection device

Technical Field

The utility model particularly relates to a detection device.

Background

To combat the social problem of drug abuse, drug testing is performed in various industries such as employment, education, sports, law enforcement, medical, and the like. Drug testing generally requires the collection of test samples prior to testing.

At present, in the market, a test strip is generally adopted to carry out instant detection on a sample, so that a detection result can be obtained quickly, and the detection result can be positive, negative or invalid. Such a detection method is simple, low in cost and easy to operate, but the detection method has some disadvantages, such as (1) compared with a laboratory accurate test, the accuracy of the detection result of the instant test strip is low, and the detection result is not credible; false positive, false negative or invalid results may occur, even with the best quality test strips, which may be due to dirty samples, or to deterioration of the chemicals used or to conditions of the sample itself that are not suitable for immediate testing, etc.; (2) when a positive result occurs, the sample provider usually argues that the sample is not self, and they require to prove that the sample is self, which requires DNA detection, but DNA detection needs to be performed again, because the original sample is possibly deteriorated or polluted and is not suitable for taking for DNA detection, but the re-acquired sample is not the same sample as the previous sample, and the sample provider does not trust, which leads to continued argumentation.

In another testing method, the sample is not tested immediately, but is collected by using a sample collecting device, and then the sample is sent to a laboratory where testing is performed. This detection method cannot obtain a preliminary detection result quickly.

Another method is to use a test strip to perform an instant test, collect the sample when a false positive occurs, send the sample to a laboratory, and perform a confirmation test in the laboratory, where the laboratory test is usually accurate, and the laboratory test can perform a quantitative test to determine the content of the drug of abuse in the sample. However, the detection method needs to collect the sample again, the collected sample is not the same sample as the previous sample, a series of supervision and supervision are needed in the process of collecting and detecting the sample again, a collector needs to affirm the identity of a sample provider faithfully and reliably, errors do not occur, the identity of the sample provider does not need to be mistaken or confused, and the like; during transport of the sample to the laboratory and during testing of the sample in the laboratory, it is ensured that the sample is not damaged or contaminated.

The current sample detection device at least comprises one cavity, and some sample detection devices comprise a plurality of cavities for detection of different purposes, but a mechanism for adjusting communication and separation between different cavities is particularly complex, and the operation is complicated.

SUMMERY OF THE UTILITY MODEL

To the above circumstances, for overcoming the defects of the prior art, the utility model provides a detection device.

In order to achieve the above object, the present invention provides the following technical solutions:

a detection device comprises a locking element which is configured to be capable of communicating or separating different cavities.

Further, the locking element is provided with a positioning strip on the side.

Furthermore, the locking element is provided with a through hole which can be communicated with different cavities.

Further, the device also includes a second channel for movement of the locking element.

Further, the second channel is closed at one end and has an entrance at the other end configured to allow entry of the locking element.

Further, the closed end of the second channel is provided with a base configured to hold the buffer reagent holding device.

Further, one end of the locking element is provided with a tip configured to be able to puncture the buffer reagent holding means or to puncture the sealing layer.

The utility model has the advantages that:

(1) the utility model discloses a locking element can adjust intercommunication and wall between the different cavitys betterly, easy operation, and it is convenient to adjust, and this locking element can also be used for pricking buffer reagent and hold device or closed layer, releases buffer reagent in to the cavity.

(2) The device of the utility model divides the sample into different cavities, and the locking element can cut off the communication between the first cavity and the second cavity; and the communication between the third cavity and the fourth cavity can be separated. The device can be used for detecting the abused drugs in the sample in real time, collecting and storing the sample for secondary confirmation detection in a laboratory, and can also be used for DNA detection and confirming the sample provider, the detection samples are all from the same sample, the accuracy of the result is ensured, the errors are reduced, and the device is simple to operate and high in accuracy when used for detecting the abused drugs.

Drawings

Fig. 1 is a schematic structural diagram of the device of the present invention.

Fig. 2 is a left side view of fig. 1.

Fig. 3 is a cross-sectional view of the locking element fully entering the second channel.

Fig. 4 is an exploded view of the inventive device (showing the structure of the locking element).

FIG. 5 is a schematic view of the locking element shown in cross-section as it is inserted into the second passage.

Detailed Description

The technical solution of the present invention will be described in further detail with reference to the accompanying drawings, and it should be noted that the detailed description is only for describing the present invention, and should not be construed as limiting the present invention.

As shown in fig. 1-5, a testing device includes a cup 5, a first channel 22 is provided in the cup 5, the first channel 22 includes a sample inlet 31, two sample outlets 32 for samples to flow out, two separated cavities are provided in the cup 5, the two cavities are a first cavity 1 and a third cavity 3, the first cavity 1 and the third cavity 3 are used for receiving samples flowing out from the two sample outlets;

the cup body is also provided with a second cavity 2 and a fourth cavity 4, the first cavity 1 and the third cavity 3 are configured to be used for storing and/or detecting samples, the second cavity 2 and the fourth cavity 4 are configured to be used for collecting samples, the first cavity 1 and the second cavity 2 can be closed and communicated, and the third cavity 3 and the fourth cavity 4 can be closed and communicated.

When the first cavity 1 is communicated with the second cavity 2, the liquid sample can be transferred between the first cavity 1 and the second cavity 2, and when the communication between the first cavity 1 and the second cavity 2 is cut off, the liquid sample cannot be transferred between the first cavity 1 and the second cavity 2; when the third cavity 3 is communicated with the fourth cavity 4, the liquid sample can be transferred between the third cavity 3 and the fourth cavity 4, and when the third cavity 3 is communicated with the fourth cavity 4, the liquid sample cannot be transferred between the third cavity 3 and the fourth cavity 4.

The utility model discloses detection device still includes locking element 6, as shown in fig. 3, locking element 6 can cut off the intercommunication between first chamber 1 and the second chamber 2, and locking element 6 can also cut off the intercommunication between third chamber 3 and the fourth chamber 4.

In some preferred manners, a first opening 7 is provided on the first chamber 1, a second opening 8 is provided on the second chamber 2, and the first opening 7 can be communicated with the second opening 8, as shown in fig. 3 and 5, in this embodiment, a first opening 7 is provided on the bottom surface of the first chamber 1, a second opening 8 is provided on the second chamber 2, and when the first opening 7 is communicated with the second opening 8, the liquid sample in the first chamber 1 can enter the second chamber 2, so as to realize the transfer of the liquid sample.

In some preferred modes, a third opening 9 is arranged on the third cavity 3, a fourth opening 10 is arranged on the fourth cavity 4, and the third opening 9 can be communicated with the fourth opening 10. As shown in fig. 3 and 5, in this embodiment, a third opening 9 is disposed on a bottom surface of the third chamber 3, a fourth opening 10 is disposed on the fourth chamber 4, and when the third opening 9 is communicated with the fourth opening 10, the liquid sample in the third chamber 3 can enter the fourth chamber 4, so as to transfer the liquid sample.

In some preferred modes, the bottom of the second cavity 2 is provided with a fifth opening 11, and a first sealing layer is arranged at the fifth opening 11, and the first sealing layer can encapsulate the sample in the second cavity 2, so that the storage and transportation of the sample are facilitated. In some preferred embodiments, the first sealing layer can be opened, the first sealing layer can be punctured, a sample can be removed, and a secondary confirmation test or a DNA test or other test can be performed in a laboratory. In some preferred modes, as shown in fig. 3 and 5, the fifth opening 11 is recessed inwards, and the first sealing layer is higher than the bottom surface of the detection device, so that the sealing layer can be prevented from being punctured during use or transportation, and the sample can flow out, be lost or be polluted.

In some preferred modes, as shown in fig. 3 and 5, a sixth opening 12 is formed at the bottom of the fourth cavity 4, and a second sealing layer is arranged at the sixth opening 12, and the second sealing layer can enclose the sample in the fourth cavity 4, so that the sample can be stored and transported conveniently. In some preferred embodiments, the second sealing layer can be opened, the second sealing layer can be punctured, a sample can be removed, and a secondary confirmation test or a DNA test or other test can be performed in a laboratory. In some preferred modes, as shown in fig. 3 and 5, the sixth opening 12 is recessed inwards, and the second sealing layer is higher than the bottom surface of the detection device, so that the second sealing layer can be prevented from being punctured during use or transportation, and the sample can flow out, be lost or be polluted.

In some preferred manners, the first cavity 1 and/or the third cavity 3 are configured to be used for detecting a sample, and at least one detecting element is disposed in the first cavity 1 and/or the third cavity 3, and the detecting element is used for detecting the presence or the amount of an analyte in the sample, so that real-time detection of the sample can be realized, and a detection result can be obtained. In some preferred modes, the detection element can be arranged on any side inner wall of the first cavity 1; the detection element may also be arranged on either side of the inner wall of the third chamber 3. In some preferred modes, a placing component for placing the detection element is further arranged on the side inner wall of the first cavity 1 and/or the third cavity 3, the detection element can be placed in the placing component, the placing component can be fixedly connected with the side inner wall of the first cavity 1 and/or the third cavity 3, and the placing component can also be detachably connected with the side inner wall of the first cavity 1 and/or the third cavity 3. In some preferred forms, the placement member is removably attached to the side inner wall of the cup body 5. In some preferred modes, a slot can be arranged on the placing component, and the detection element can be placed in the slot. In other preferred ways, the first chamber 1 and/or the third chamber 3 may be configured to store only the liquid sample, not for detection.

In some preferred embodiments, the "test element" can be any test device that provides a test result. In some embodiments, the detection element is a test strip. The test strip may have specific binding molecules immobilized on the test strip and reagents for performing an immunoassay. However, in other embodiments, the test element may also contain a chemical reaction-based test agent, a biological-based test agent (e.g., an enzyme or ELISA assay), or a fluorescent-based test agent, among others. In addition, in other embodiments, the test element may have other reagents thereon that can be used to detect the presence or quantity of the analyte in the sample. In one embodiment, the detection element comprises a reagent for detecting the presence of a drug of abuse. However, in other embodiments, the detection element may be any element that provides an indication of the result of the assay. For example, some chemical or biological indicator reagents may be used. In some preferred modes, the detection element is a test strip, the test strip is placed in the first cavity 1 and/or the third cavity 3, and after the sample enters the first cavity 1 and/or the third cavity 3, the running plate detection is performed to obtain a detection result.

The sample detected by the utility model can be any fluid sample. Fluid samples suitable for testing by the present invention include oral fluid, saliva, whole blood, serum, plasma, urine, spinal fluid, biological extracts, mucus, and tissue. "saliva" refers to the secretions of the salivary glands. An "oral fluid" is any fluid present in the oral cavity. The analyte to be detected may be any analyte for which the detection element may be made. In one embodiment, the analyte is a drug of abuse. The analyte of interest may also be a hormone, protein, peptide, nucleic acid molecule, pathogenic agent, and specific binding pair member. A "drug of abuse" (DOA) is a drug used for non-medical purposes, usually for hallucinogenic effects. Abuse of such drugs can lead to physical and mental harm and, in some cases, dependence, addiction, and even death. Examples of DOAs include cocaine, amphetamines (e.g., black beans, white beans, amphetamine tablets, dextrorotation amphetamines, dexes, beans), methamphetamines (crank, methamphetamine, crystal, speed), barbiturates (RochePharmaceuticals, Nutley, New Jersey), sedatives (i.e., hypnotics), lysergic acid diethylamide (LSD), sedatives (downs, gofiballs, barbs, blue devils, yellows, lues), tricyclic antidepressants (TCAs, e.g., imipramine, amitriptyline, and doxepin), phencyclidine (PCP), tetrahydrocannabinol, and opiates (e.g., morphine, opium, codeine, heroin).

In some preferred forms, a second passage is provided in the cup 5 for the movement of the locking element 6. As shown in fig. 3 and 5, the second passage is located between the first chamber 1 and the second chamber 2, and between the third chamber 3 and the fourth chamber 4. In some preferred forms, the second channel is closed at one end and has an access opening 13 at the other end to allow access to the locking element 6. In some preferred forms, as shown in fig. 3-5, the end of the second channel closed is provided with a base 14 configured to receive and hold a buffer reagent holding means, which in some preferred forms has no fixed shape and has a shape that can be changed when filled with buffer reagent; when the buffer reagent is released, the shape of the buffer reagent holding device changes. Buffer reagent holds device can be the sacculus or the sack that can store buffer reagent, after adorning buffer reagent, holds device with buffer reagent and places in base 14, and base 14 can hold device with buffer reagent and fix. In some preferred forms, the base is configured to hold a buffer reagent, the buffer reagent being enclosed within the base, and in some preferred forms, the open end of the base is enclosed by a third enclosing layer, thereby enclosing the buffer reagent within the base. In some preferred forms, the buffer reagent may be a diluent or a solution that reduces the viscosity of the liquid sample or other functional reagent; for example, some samples may not be tested in their original state, or the test results may be unsatisfactory, and often require pre-treatment to change their physical or chemical properties, for example, by buffer solutions to help dilute or buffer the samples before testing.

In some preferred modes, the buffer reagent containing device is provided with an opening, and the opening is closed and can be opened. In other preferred modes, the buffer reagent containing device is not provided with an opening, for example, the buffer reagent containing device is a capsule or a bag capable of storing the buffer reagent, and any place can be punctured to allow the buffer reagent to flow out.

In some preferred forms, a detent 15 is provided in the second passage to facilitate insertion of the locking element 6 into the second passage. As shown in fig. 1-2, in this embodiment, positioning recesses 15 are provided on two opposite sides of the second channel, which facilitates the entry of the locking element 6 into the channel.

In some preferred forms, as shown in fig. 4, the locking element 6 is provided with a positioning rib 16 on the side, and the positioning rib 16 is matched with the positioning groove 15. The positioning rib 16 can enter the positioning groove 15 and can slide along the positioning groove 15.

In some preferred forms, as shown in fig. 3-5, the locking element 6 is provided with a through hole 17, the through hole 17 being able to communicate the first chamber 1 with the second chamber 2. When the through hole 17 corresponds to the first opening 7 and the second opening 8, the first chamber 1 is communicated with the second chamber 2, and the liquid in the first chamber 1 can flow into the second chamber 2 through the through hole 17. When the through hole 17 is not crossed with the first opening 7 and the second opening 8, the first opening 7 and the second opening 8 are blocked by the locking element 6, the communication between the first cavity 1 and the second cavity 2 is blocked, the liquid sample cannot enter the second cavity 2 from the first cavity 1, and the second cavity 2 is sealed, so that the sample with a certain volume can be stored and preserved.

In some preferred forms, as shown in fig. 3-5, one end of the locking element 6 is provided with a pointed end 18 configured to pierce the buffer reagent holding means or an opening in the buffer reagent holding means or a third closure layer to allow the buffer reagent to flow out.

In some preferred forms, as shown in fig. 1-5, the apparatus further includes a lid 19, the lid 19 being capable of closing the cup 5. In some preferred modes, as shown in fig. 3-5, the upper surface of the cup cover 19 extends out of four side walls, the side walls of the cup cover 19 are made of semi-flexible materials and can be pressed and rebound automatically, the side walls are pressed inwards, the side walls of the cup cover 19 can be loaded into the cup body 5, after the cup body 5 is loaded, the side walls rebound and cling to the inner wall of the cup body 5, so that the cup body 5 can be sealed after the cup cover 19 covers the cup body 5, and the whole device is good in sealing performance and free of liquid leakage. In some preferred modes, as shown in fig. 3-5, a connecting column 20 is fixedly arranged on the lower surface of the cap 19, and the connecting column 20 is fixedly connected with the cap 19.

In some preferred modes, the device further comprises a collecting element 21, the collecting element 21 can collect or release a liquid sample, and the collecting element 21 is fixedly connected with the cup cover 19, so that the collecting element 21 can collect, transfer and release the sample conveniently, the cup cover 19 is held to operate, the operation of the collecting element 21 can be realized, and finally the collection, transfer, release and the like of the sample can be realized. In some preferred forms, as shown in fig. 3 and 5, the collecting element 21 is fixedly connected to the connecting column 20 on the cap 19, and the collecting element 21 can be adhered or welded to the connecting column 20 by a sealant or a hot melt adhesive or other glue, or can be connected to the connecting column 20 by any suitable means. In other preferred forms, the collecting element 21 is removably attached to the cap 19. In some preferred forms, the acquisition element 21 is compressible, for example, by absorbing a liquid sample with the compressible acquisition element 21 and then causing the acquisition element 21 to release the sample by squeezing the acquisition element 21. Compressible refers to a material property in which the shape of a material can be deformed by mechanical pressure to squeeze liquid out of the material while the material retains the liquid. Acquisition element 21 may be made of any material that absorbs and retains liquid. In some embodiments, the acquisition element 21 is a sponge, but in other embodiments it may be a nonwoven, absorbent paper, nylon, cotton, or any other material that can absorb and retain liquids. When the material of the acquisition element 21 is a sponge, it may be natural or synthetic. In the illustrated embodiment, as shown in fig. 3-5, the collection element 21 is a cylindrical sponge material adapted to be placed in the mouth of a subject to collect saliva. In other embodiments, however, the capture element 21 may be any suitable and convenient shape. In certain embodiments, the collection element 21 is treated with a chemical composition (e.g., citrate or other chemical) to promote salivation and facilitate absorption by the collection element 21.

In some preferred forms, the first channel 22 is capable of receiving and retaining the collection element 21 for use in cooperation with the collection element 21, in some preferred forms the first channel 22 is disposed perpendicular to the second channel, and in some preferred forms the first channel 22 is disposed between the first and third lumens 1, 3. In some preferred forms, a projection 23 is provided in the cup 5, configured to press against the collection element 21 to release the sample. In some preferred modes, the bulge 23 is positioned above the second channel, in some preferred modes, the bulge 23 is positioned right below the first channel 22, a part of the bulge 23 extends into the first channel 22, no seal is formed between the bulge 23 and the first channel 22, and an abdication space is reserved, so that the liquid sample can conveniently flow out of the abdication space; when the sampling device is used, the cup cover 19 is taken up, the sampling element 21 is used for sampling, then the sampling element 21 is inserted into the first channel 22, the sampling element 21 is moved downwards to be contacted with the bulge 23, the sampling element 21 is continuously moved downwards, the sampling element 21 is pressed by the bulge 23 to release a sample, and the sample is divided into two parts which respectively flow to the first cavity 1 and the third cavity 3.

In some preferred embodiments, the protrusion 23 is a dome-shaped protrusion 23, and the protrusion 23 may have other suitable shapes, so that the collecting element 21 can contact the protrusion 23 and be pressed to release the sample, and the sample can smoothly flow to the first and third chambers 1 and 3.

In some preferred forms, the front end of the locking element 6 is fitted with a sealing ring, which acts as a seal so that the liquid sample cannot flow from the slit to elsewhere.

The utility model also provides a use method of this detection device, including following step: (the samples are described in connection with FIGS. 1-5 for saliva samples)

(1) Placing the collection element 21 in the mouth of the user, the collection element 21 continuously absorbing saliva or otherwise collecting saliva samples;

(2) then, the collecting element 21 is inserted into the first passage 22, the collecting element 21 is moved downwards to contact with the protrusion 23, the collecting element 21 is continuously moved downwards, the collecting element 21 is pressed by the protrusion 23, the sample is released, and the sample is divided into two parts and flows to the first cavity 1 and the third cavity 3 respectively; the sample flows into the second cavity 2 through the first opening 7 of the first cavity 1 and the second channel, meanwhile, the sample in the third cavity 3 flows to the fourth cavity 4 through the third opening 9 and the second channel, and the sample is stored in the second cavity 2 and the fourth cavity 4;

(3) after a certain volume of sample is collected in the second chamber 2 and the fourth chamber 4 respectively (the sample can be used for laboratory confirmation detection or DNA detection or other detection), the locking element 6 is inserted into the second channel (the locking element 6 is inserted into the second channel, as shown in fig. 5, this step can also be operated in step (2)), the locking element 6 is pushed inwards, so that the locking element 6 slides inwards along the positioning groove 15, the opening 17 is simultaneously communicated with the first opening 7 and the second opening 8, the liquid sample can enter the second chamber 2 from the first chamber 1, at this time, the third chamber 3 and the fourth chamber 4 are in a communicated state, as shown in fig. 5, the liquid sample can enter the fourth chamber 4 from the third chamber 3; continuing to push the locking element 6 inward, when the first opening 7 and the second opening 8 cannot be communicated with the opening at the same time (i.e. when the first opening 7 is communicated with the opening, the second opening 8 is not communicated with the opening, or when the second opening 8 is communicated with the opening, the first opening 7 is not communicated with the opening), the communication between the first cavity 1 and the second cavity 2 is cut off, and the liquid sample cannot enter the second cavity 2 from the first cavity 1; continued inward pushing of the locking element 6, the tip of the locking element 6 into the base 14, and eventually the tip 18 of the locking element 6 pierces the buffer reagent holding means or the third enclosing layer (the buffer reagent holding means and the third enclosing layer are not shown in fig. 3), the buffer reagent flows out, the buffer reagent can enter the fourth chamber 4, continued inward pushing of the locking element 6, until the locking element 6 can no longer continue to move inward, as shown in fig. 3 (the sealing ring is not shown in fig. 3), at this time, the sealing element seals the gap, the communication between the third chamber 3 and the second channel is cut off, the communication between the fourth chamber 3 and the second channel is cut off, the communication between the third chamber 3 and the fourth chamber 4 is cut off, a certain volume of sample (which also includes a buffer reagent) is stored in the fourth chamber 4, and the samples stored in the second chamber 2 and the fourth chamber 4 can be used for secondary confirmation detection or detection for other purposes. After the communication between the first cavity 1 and the second cavity 2 is separated and the communication between the third cavity 3 and the fourth cavity 4 is separated, the sample respectively flows into the first cavity 1 and the third cavity 3 and is respectively stored in the two cavities; if a test strip is provided in the third chamber 3, detection of certain substances in the sample can be achieved in the third chamber 3, and likewise if a test strip is provided in the first chamber 1, detection of certain substances in the sample can be achieved in the first chamber 1.

In this embodiment, the liquid sample may be a saliva sample, and the first chamber 1 or/and the third chamber 3 may be provided with test strips, which are capable of detecting abused substances, such as cocaine, amphetamines, sedatives, etc., in real time, giving a preliminary test result. The second chamber 2 and the fourth chamber 4 store a quantity of sample that can be used for secondary confirmation testing or for DNA testing or for testing of other substances. The utility model discloses a device not only can carry out the instant detection to the abuse medicine in the sample, can be sent the laboratory and carry out the secondary and confirm the detection, can also be used for DNA to detect, confirms the sample provider, and foretell detection sample all comes from same sample, ensures the accuracy of result, reduces the error, adopts this device to carry out the detection of abuse medicine, easy operation, and the accuracy is high.

In some preferred embodiments, each test requires a tag number to be attached to the test device, which can be used as the sample number, and the mobile application is used to record the sample number, the time the sample was collected, the time and date of the test, who collected the sample, the collection process, etc. after the test is collected, the results can be uploaded to a database.

It is obvious that the described embodiments are only some of the embodiments of the present invention, and not all of them. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts shall belong to the protection scope of the present invention.

Claims (6)

1. The detection device is characterized by comprising a locking element, a detection unit and a detection unit, wherein the locking element is configured to be capable of communicating or separating different cavities; one end of the locking element is provided with a tip configured to be able to puncture the buffer reagent holding means or to puncture the closing layer.

2. A testing device according to claim 1 wherein the locking element is flanked by locating strips.

3. A testing device according to claim 1 wherein the locking member is provided with a through hole which allows communication between different chambers.

4. A testing device according to claim 1 wherein the device further comprises a second passage for movement of the locking element.

5. A testing device according to claim 4 wherein the second passage is closed at one end and has an access opening at the other end configured to allow access to the locking element.

6. A test device according to claim 5, wherein the closed end of the second channel is provided with a base configured to hold the buffer reagent holding means.

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