CN210401424U - Sample collection member - Google Patents

Abstract

The utility model relates to a sample collecting component used for being connected with a detection device, which comprises a collecting rod and an absorbing element with a cavity, wherein the absorbing element is sleeved on the collecting rod through the cavity; at least two ribs are arranged on the collecting rod, and a diversion trench is formed between the ribs. Utility model collecting element can both reduce the detection device volume with detection device integral structure, realizes integration detection, convenient operation again.

Description

Sample collection member

Technical Field

The utility model relates to a device that sample collection part and sample were collected and were detected, in particular to be used for collecting the fluid sample and make the sample mix collecting element who detects again behind the buffer solution.

Background

The following background is provided to aid the reader in understanding the present invention and is not admitted to be prior art.

The technology of detecting whether an analyte exists in a sample by using the principle of an immunological binding reaction is widely used in various fields. It can be used to detect analytes in various biological samples (saliva, blood, urine, serum, sweat, etc.) to monitor diseases and human health (early pregnancy, tumors, infectious diseases, drugs, etc.). The underlying principle of such detection techniques is to establish the ability to specifically bind between immune molecules, such as antibodies and antigens, haptens/antibodies, biotin and avidin, and the like.

In the field of medical diagnosis, it is a common method to collect a test liquid sample by using a testing device or a testing cup and determine whether the liquid sample contains an analyte. Such test devices or test cups typically require the sample to be collected in a sample container, and the associated technician includes a test strip and immerses a portion of the test strip in the sample, removes the test strip after a period of time, and reads the test results.

US2004/0184954 and US2004/0237674 disclose devices for collecting saliva and detecting the presence of illegal drug components in the saliva. In both patents, devices and methods are provided for collecting and testing saliva, wherein after a sample is collected on a collector, the sample is squeezed by an external force applied to an absorbent member on the collector into a collection chamber, and then tested.

However, the existing detection device has the following problems:

1. a sufficient amount of sample is required. Most of the collected samples are used for detecting illegal drugs or drugs of abuse, the examinees are not matched, or the sample size of the examinees is small, for example, the saliva collection amount is small, and sometimes a plurality of analytes in the samples need to be detected simultaneously, so that a large amount of samples are needed.

2. Most of detection devices are of split structures and are operated in a split mode. The operating requirements are relatively high.

3. The detection device is not small enough in structure and inconvenient to carry.

SUMMERY OF THE UTILITY MODEL

According to the above problem, the utility model provides a sample collecting part for connecting on detection device, through the collecting part of this structure, can both reduce the detection device volume with detection device integrated structure, realize integration detection, convenient operation again.

In a specific technical scheme, the utility model provides a sample collecting component for connecting to a detection device, which comprises a collecting rod and an absorbing element with a cavity, wherein the absorbing element is sleeved on the collecting rod through the cavity; at least two ribs are arranged on the collecting rod, and a diversion trench is formed between the ribs.

In some preferred embodiments, the ribs are of a stepped configuration; the absorbing element is located in the upper step.

In some preferred embodiments, the collecting rod is provided with a conical projection adjacent the collecting end of the absorbent element.

In some preferred embodiments, the connecting end of the collection rod is provided with a barb; the end of the barb is pointed and conical.

The utility model also provides a device of collection and detection of integral structure makes the collection and the detection of sample can realize the integration, reduces the product structure and reduces the person's of being examined the operation degree of difficulty to, as far as possible few let the operator contact the sample, reduce the infection probability, improve operator safety guarantee. In addition, the detection device is used for detecting, the sample requirement is greatly reduced, and the success of detection is facilitated.

Particularly, the utility model provides a sample collection and detection device, which comprises a detection cavity and a collection part, wherein the detection cavity is connected with the collection part and is communicated with the collection part through liquid; the inner wall of the detection cavity is provided with a first ladder, and the collecting part comprises a collecting rod and an absorbing element sleeved on the collecting rod; a barb is arranged at the connecting end of the collecting rod, and the tail end of the barb is pointed and conical; the first step of barb block through the link makes detection chamber and collecting element be connected.

In some preferred embodiments, the collecting rod connecting end of the collecting component is inserted into the detection cavity from the bottom of the detection cavity, the barb end of the connecting end enters the detection cavity, then the open end of the barb is compressed, and the barb and the connecting end enter the detection cavity; after the open end of barb reached first ladder department, because of detecting intracavity footpath grow, the barb open end kick-backs to the reconversion, and the barb block is in first ladder department.

In some preferred embodiments, at least two ribs are arranged on the collecting rod, and a diversion trench is formed between the ribs; the liquid on the absorption element is communicated with the liquid in the detection cavity through the diversion trench.

In some preferred embodiments, the ribs are of a stepped configuration; the absorbing element is located in the upper step.

In some preferred embodiments, the collecting rod is provided with a conical projection adjacent the collecting end of the absorbent element.

In some preferred embodiments, the sample collection and testing device further comprises a cover covering the testing chamber, and a card slot for accommodating the testing element is formed in the cover.

In some preferred embodiments, the inner wall of the detection chamber is further provided with a second step located above the first step.

In some preferred embodiments, the sample collection and detection device further comprises a buffer pad; the cushion is located on the second step. The buffer pad serves to prevent the wash liquid from the absorbent member from rushing too vigorously, rushing into the detection chamber in large amounts, and to cushion the test element located in the detection chamber.

In some preferred embodiments, the liquid entering the detection chamber through the channels of the collection rod flows into the buffer pad and then flows from the buffer pad onto the test element.

In some preferred embodiments, the sample collection and detection device further comprises a buffer chamber, a sealing sheet for sealing the buffer chamber, and a pipetting chamber hermetically connected to the buffer chamber; the buffer liquid is sealed in the buffer cavity. In some embodiments, the sealing sheet is an aluminum foil sheet.

In some preferred embodiments, the outer wall of the bottom of the detection chamber is provided with a sealing gasket, the collection component and the detection chamber enter the pipetting chamber, and a seal is formed between the detection chamber and the pipetting chamber.

In some preferred embodiments, the collection member attached to the detection chamber is inserted into the pipetting chamber, first, the absorbent element of the collection member is positioned directly above the orifice of the pipetting chamber; secondly, the collecting component continues to move along the direction of inserting into the pipetting cavity, and the detection cavity enters the pipetting cavity to form a seal; thirdly, the collecting component continues to move along the direction of inserting into the pipetting cavity, and the conical projection of the collecting rod contacts the sealing sheet; finally, the collecting component continues to move along the direction of inserting into the pipetting cavity to enable the conical projection of the collecting rod to reach the bottom of the buffer cavity, the conical projection of the collecting rod punctures the sealing sheet, the absorbing element enters the buffer cavity, and the buffer solution enters the absorbing element to be mixed with the sample on the absorbing element; the mixed liquid flows into the detection cavity along the diversion trench of the collection rod through the absorption element.

In some preferred embodiments, the detection chamber is transparent or provided with a transparent window.

In some preferred embodiments, the test element may be one or more. The plurality of test elements may each detect a different analyte in the sample.

In some preferred embodiments, the buffer chamber is in threaded connection with the pipetting chamber.

In some preferred embodiments, the buffer pad is in contact with the test element.

In some preferred embodiments, a cover is threaded over the detection chamber.

On the other hand, the utility model also provides a method for collecting and detecting the liquid sample, which comprises a sample collecting and detecting device, wherein the device comprises a detecting cavity and a collecting component, and the detecting cavity is connected with the collecting component and is in liquid communication; the inner wall of the detection cavity is provided with a first ladder, and the collecting part comprises a collecting rod and an absorbing element sleeved on the collecting rod; a barb is arranged at the connecting end of the collecting rod, and the tail end of the barb is pointed and conical; the first step is clamped through the barb of the connecting end so that the detection cavity is connected with the collecting component; the collecting rod is provided with at least two ribs, and a diversion trench is formed between the ribs; the sample collecting and detecting device also comprises a buffer cavity, a sealing sheet for sealing the buffer cavity and a liquid transferring cavity which is connected with the buffer cavity in a sealing way; the buffer liquid is sealed in the buffer cavity; wherein:

collecting the sample with the collection member such that the absorbent member is filled with the liquid sample;

inserting the collection member filled with the liquid sample and the detection chamber connected thereto into the pipetting chamber;

moving the collecting part in the pipetting cavity along the direction of inserting into the pipetting cavity, and enabling the collecting part to reach the sealing sheet;

the collecting component pierces the sealing sheet on the buffer cavity and enters the buffer cavity, so that the sample on the absorption element is mixed with the buffer solution;

allowing the mixed liquid to flow along the absorption element and the diversion trench to the test element in the detection cavity for detection;

and reading the detection result on the test element.

In some preferred embodiments, the collecting rod is provided with a tapered projection adjacent the collecting end of the absorbent element; the sealing piece is pierced by the conical projection.

In some preferred embodiments, the device for collecting and testing a sample further comprises a cover for covering the testing chamber, wherein a slot for accommodating the testing element is formed in the cover; wherein, after the cover covers the detection cavity, the test element is positioned in the detection cavity.

In some preferred embodiments, the sample collection and detection device further comprises a buffer pad; a second ladder is arranged in the detection cavity; the buffer cushion is positioned on the second step; the liquid entering the detection cavity through the flow guide groove of the collecting rod firstly flows into the buffer pad and then flows into the test element from the buffer pad.

In some preferred embodiments, the outer wall of the bottom of the detection chamber is provided with a sealing gasket, and after the collection component and the detection chamber enter the pipetting chamber, a seal is formed between the detection chamber and the pipetting chamber.

Advantageous effects

The utility model discloses a device that sample was collected and was detected realizes the collection of sample, slowly-releasing and detection function through the integral type structure of collecting element and detection chamber and cushion chamber. Firstly, the detection device is easy to operate, and the use difficulty of an operator is reduced. And secondly, the frequency and time of the operator contacting the sample are effectively reduced, the probability of the operator being infected is reduced, the safety of the operator is ensured, and the method is particularly suitable for HIV detection. Thirdly, the integrated detection device is provided with a buffer solution, so that the requirement on the collection amount of the sample is low, and the collection amount is optimized from milliliter level to micro-upgrade. Finally, due to the integrated structure, the acquisition, the slow release and the detection are realized in one step, and the success rate of the detection is improved.

Drawings

Fig. 1 is an exploded view of the device for collecting and detecting samples according to the present invention.

Fig. 2 is a schematic view of the device for collecting and detecting samples according to the present invention.

Fig. 3 is a cross-sectional view of the device for collecting and detecting samples according to the present invention.

Fig. 4 is an exploded view of the sample collection member of the present invention.

Fig. 5 is a schematic view of a cap according to the present invention.

Fig. 6 is a cross-sectional view of the device for sample collection and testing of the present invention before use.

Fig. 7 is a cross-sectional view of the device for collecting and detecting samples according to the present invention, wherein the collecting member reaches the buffer chamber.

Fig. 8 is a cross-sectional view of the device for collecting and detecting samples according to the present invention, wherein the collecting member reaches the buffer chamber to buffer and detect the samples.

Reference numerals

Sample collecting and detecting device 100, sample collecting part 10, collecting rod 11, ribs 111, flow guide groove 112, upper step 113, lower step 114, tapered bump 115, barb 116, collecting rod connecting end 117, collecting rod collecting end 118, absorbing element 12, absorbing element cavity 121, detecting cavity 20, first step 21, second step 22, buffer pad 23, transfer cavity 30, clamping strip 31, buffer cavity 40, testing element 50, buffer solution 60, sealing sheet 70, sealing sheet 80, cover 90 and cover clamping groove 91

Detailed Description

The structures referred to in the present invention or these terms of art used are further described below.

Detection of

Detection refers to assaying or testing for the presence of a substance or material, such as, but not limited to, a chemical, organic compound, inorganic compound, metabolic product, drug or drug metabolite, organic tissue or a metabolite of organic tissue, nucleic acid, protein, or polymer. In addition, detection indicates the amount of the test substance or material. Further, the assay means immunodetection, chemical detection, enzyme detection, and the like.

Sample(s)

The term sample as used herein refers to a substance that can be used to detect, assay or diagnose the presence of an analyte of interest. The sample may be, for example, a liquid sample, which may include blood, plasma, serum, urine, saliva, and various exudates, and may also include a liquid solution formed by pre-treating a solid sample and a semi-solid sample. The collected sample may be used for immunoassay, chemical assay, enzymatic assay, etc. to detect the presence of the analyte. In a preferred embodiment, the sample of the present invention is a saliva sample.

Analyte substance

Any analyte can be analyzed using the device and method of the present invention. The analyte can be detected in any liquid or liquefied sample, such as urine, saliva, blood, plasma, or serum. The analyte may also be a hapten, which includes a drug of abuse (e.g., a drug of abuse). By "drug of abuse" (DOA) is meant the use of a drug (usually acting to paralyze nerves) at a non-medical destination. The device can also be used for detecting the detection which belongs to the medical application and is easy to take overdose, such as tricyclic antidepressant (imipramine or the like) and acetaminophen, etc. After being absorbed by human body, the medicines are decomposed into different small molecular substances, and the small molecular substances exist in body fluids such as blood, urine, saliva, sweat and the like or exist in partial body fluids.

Test element 50

The test element 50 may be selected from a lateral flow test strip that detects a variety of analytes. Of course, other suitable test elements may be used with the present invention. Various test elements may be combined and used in the present invention. One form is a test strip. Test strips for the analysis of analytes, such as drugs or metabolites indicative of a physical condition, in a sample may be in various forms, such as immunoassay or chemical assay forms. The test strip may be used in a non-competitive or competitive assay format. The test strip includes a bibulous material having a sample receiving area, a reagent area, and a test area. The sample is applied to the sample receiving area and flows by capillary action to the reagent area. In the reagent zone, the sample binds to the reagent if the analyte is present. The sample then continues to flow to the detection zone. Other reagents, such as molecules that specifically bind to the analyte, are immobilized at the detection zone. These reagents react with the analyte (if present) in the sample and bind the analyte to the zone, or to one of the reagents of the reagent zone. The label for indicating the detection signal is present in the reagent zone or in a separate label zone.

Typical non-competitive assay formats are: if the sample contains the analyte, a signal is generated, and if the analyte is not contained, no signal is generated. In a competition method, a signal is generated if the analyte is not present in the sample and no signal is generated if the analyte is present.

The test element 50 may be a test strip, and may be selected from a material that absorbs or does not absorb water. The test strip may include a variety of materials for liquid sample delivery. One of the test strips may be coated with another material, such as a nitrocellulose membrane coated with filter paper. One region of the test strip may be selected from one or more materials and another region may be selected from a different one or more materials. The test strip may be adhered to some support or hard surface for improved strength when the test strip is held in place. The analyte is detected by a signal producing system, such as one or more enzymes that specifically react with the analyte, and one or more compositions of the signal producing system are immobilized on the analyte detection zone of the test strip by a method such as that described above for the immobilization of a specific binding substance on the test strip. The signal-producing substance may be on the sample-receiving zone 201, the reagent zone, or the detection zone, or the entire test strip, and the substance may be impregnated on one or more materials of the test strip. A solution containing the signal is applied to the surface of the strip or one or more materials of the strip are immersed in the solution containing the signal. The strip to which the solution containing the signal substance was added was dried.

The various regions of the test strip may be arranged as follows: a sample receiving area, a reagent area, a detection area, a control area, a sample adulteration area and a liquid sample absorption area. The control zone is located behind the detection zone. All zones may be arranged on a strip of test paper using only one material. It is also possible to use different materials for the different zones. The zones may be in direct contact with the liquid sample, or different zones may be arranged according to the direction of flow of the liquid sample, with the ends of each zone being contiguous with and overlapping the ends of the other zone. The material used can be a material with good water absorption such as filter paper, glass fiber or nitrocellulose membrane. The test strip may take other forms.

Detection chamber 20

The detection chamber 20 is generally a cavity for accommodating the test element 50 and allowing the liquid sample to enter the cavity 20 to contact the test element 50 for detection. The shape of the test element 50 may be varied and may be designed according to the shape and number of test elements to be accommodated. The utility model discloses in, the test element is test paper strip 50, and consequently, in one embodiment, detection chamber 20 is the tube structure, and test paper strip 20 is located this barrel. In other embodiments, the test chamber 20 is provided with a cover 90 for sealing the upper opening, and the test strip 50 is fixed on the cover 90 and thus is relatively fixed in the test chamber 20. In other preferred embodiments, the cartridge 20 has a window positioned to correspond to the test area of the test strip to facilitate viewing of the test results from the test strip. Or in other embodiments, the cylinder body is transparent, so that the test result of the test strip can be observed conveniently.

In the following detailed description, reference is made to the accompanying drawings, which form a part hereof, and in which is shown by way of illustration specific embodiments in which the invention may be practiced. We do not exclude that the invention can also be implemented with other embodiments and that the structure of the invention can be changed without violating the scope of the invention.

As shown in fig. 1, fig. 4 and fig. 6-8, in the present invention, the collecting member 10 includes a collecting rod 11 and an absorbing element 12, wherein the absorbing element has a cavity 121, and is sleeved on the collecting rod 11 through the cavity 121. In one embodiment, the absorbent member 12 is a sponge material, which is capable of absorbing liquids. More specifically, the sponge is a medical sponge.

At least two ribs 111 are arranged on the body of the collecting rod 11, the ribs 111 protrude from the body of the collecting rod 11, so that a guiding groove 112 is formed between the protruding ribs 111, and the guiding groove 112 is used for guiding the liquid to flow through. More specifically, the rib 111 has a stepped structure, i.e., one portion of the rib 111 protrudes higher than the other portion. The high convex portion is an upper step 113 and the low convex portion is a lower step 114. Wherein the absorbing element 12 is sleeved on the upper step 113, that is, the rib upper step 113 of the collecting rod is contacted with the inner wall of the cavity 121 of the absorbing element, so that the absorbing element 12 is fixed on the collecting rod 11. The ribs of the rib lower step 114 are low in rib protrusion, so that when the liquid on the absorption element 12 is extruded to flow to the guide groove 112 and flows along the collecting rod 11, liquid communication can be realized between the lower step 114 and the guide groove 112, and liquid mixing and liquid circulation are facilitated.

The collecting rod 11 is terminated by a collecting end 118 and a connecting end 117, respectively, wherein the absorbing element 12 is located at the collecting end 118. In one embodiment, a tapered protrusion 115 is provided at the end of the collection end 118. The tapered projection 115 is capable of piercing a relatively thin sheet-like object. Such as a metal foil, e.g. aluminum foil, tin foil, etc., or a paper sheet, a plastic sheet, etc. In other embodiments, the connecting end 117 of the collection rod is provided with a barb 116, as shown in fig. 4, the barb 116 is hollowed out, and when pressure is applied to the barb 116, the open end of the barb 116 moves towards the hollow, so that the outer circumference of the barb is reduced, the barb is conveniently inserted into a cavity with a certain volume, and when the pressure is removed, the open end of the barb 116 is restored. More specifically, the distal end of barb 116 is tapered to facilitate entry of the connecting end 117 of the collection rod into the cavity.

As shown in fig. 1-8, the utility model discloses a device 100 that sample was collected and was detected, at first including detecting chamber 20 and collecting element 10 to, detect chamber 20 and collecting element 10 fixed connection, it is concrete, detect chamber 20 and be the tube structure, and, the internal diameter of this barrel has cascaded change, divide into the different internal diameter of three-section altogether, by detecting chamber 20 bottom to top, the cascaded grow gradually of internal diameter of cavity. Therefore, the inner wall of the detection cavity 20 is provided with a first step 21 and a second step 22, the connecting end 117 of the collecting component is inserted from the bottom of the detection cavity 20, the outer periphery of the barb 116 is larger than the inner periphery of the bottom of the detection cavity 20, the barb 116 is compressed, the open end is sunk into the cavity in the middle, so that the outer periphery of the barb 116 is adapted to the inner periphery of the bottom of the detection cavity, the connecting end 117 enters the detection cavity 20 until the whole barb 116 is located at the first step 21, the barb 116 is not compressed due to the fact that the inner diameter of the first step of the detection cavity 29 is enlarged, the open end returns to the original position, and thus the diameter of the whole barb 116 is larger than the inner diameter of the detection cavity 20 below the first step 21, so that the barb 116 is clamped at the first step 21, the collecting rod 11 is fixedly connected with the.

A cover 90 is disposed on the top of the detection chamber 20, and the cover 90 seals the detection chamber 20. In one embodiment, a cover 91 is threaded over the detection chamber 20. Meanwhile, in the present invention, the cover 90 is also used to fix the test element 50. In one embodiment, the test element 50 is a test strip. Specifically, the test strip may be multiple, and is used for different analyte detection. The cover 90 is provided with a plurality of slots 91 as shown in fig. 5, but of course, the slots 91 may be provided in plurality on the cover 90 for holding the ends of the test strip 50, so that the test strip 50 is fixed on the cover 90. After the cover 90 covers the detection chamber 20, the test strip 50 is fixedly positioned in the detection chamber 20.

In order to allow a slow flow of liquid into the test element 50, i.e. the sample area of the test strip, and also to avoid excess liquid entering the detection chamber 20, the detection area of the test element 50 (test strip) is also flooded, ensuring the validity of the detection, a buffer pad 23 is placed on the second step 22 above the first step 21. In some preferred embodiments, the sample end of the test element 50 is in zero-gap contact with the bumper pad 23, which ensures that the test element 50 absorbs enough liquid to ensure a successful detection.

After being squeezed, the liquid on the absorption element 50 flows into the diversion trench 112, flows into the detection chamber 20 through the diversion trench 112 and the lower step 114 of the rib, reaches the buffer pad 23 for buffering, and finally flows onto the test element 50 for detection.

The utility model discloses in, some samples need mix the slowly-releasing with buffer solution 60 before the detection, therefore, this sample collection and the device that detects still include cushion chamber 40, and this cushion chamber 40 internal storage has buffer solution 60 to and include the gasket 70 of sealing the buffer solution in the cushion chamber. And a pipetting chamber 30 sealingly connected to the buffer chamber, the pipetting chamber 30 being adapted to receive the absorbing member 12 and to transfer the buffer liquid 60 to the absorbing member 12 and the detection chamber 20. In one embodiment, the buffer chamber 40 is threadably connected to the pipetting chamber 30 to form a seal therebetween. In a specific embodiment, a clamping strip 31 is provided in the pipetting cavity 30 for fixing the collecting member 10 in such a way that the collecting member 10 is prevented from rotating in the pipetting cavity 31 during insertion.

In some embodiments, the outer wall of the bottom of the detection chamber 20 is provided with a sealing gasket 80, the collection component 10 and the detection chamber 20 enter the pipetting chamber 30, and the pipetting chamber is sealed by the sealing gasket contacting with the inner wall of the pipetting chamber.

In use, the collecting member 10 connected to the detection chamber 20 is inserted into the pipetting chamber 30, and first, the absorbent element 12 of the collecting member is positioned directly above the orifice of the pipetting chamber 30; secondly, the collecting component 10 continues to move along the direction of inserting into the liquid transferring cavity 30, and the detection cavity 20 enters the liquid transferring cavity 30 to form a seal; thirdly, the collecting member 10 continues to move in the direction of insertion into the chamber 30, and the tapered projection 115 of the collecting rod contacts the sealing piece 70; finally, the collection component 10 continues to move in the direction of insertion into the chamber 30, so that the tapered projection 115 of the collection rod reaches the bottom of the buffer chamber, and in the process, the tapered projection 115 of the collection rod pierces the sealing sheet 70, the absorbent member 12 enters the buffer chamber 40, and the buffer solution 60 enters the absorbent member 12 to mix with the sample on the absorbent member 12; the mixed liquid flows through the absorbent member 12 along the channels 112 of the collection rod into the detection chamber 20.

The method of the present invention for collecting and testing a liquid sample is described in detail below.

Firstly, the sample collection and testing device 100 seals the buffer fluid 60 in the buffer chamber 40 during the production process, and the sealing sheet 70 is fixed at the opening of the buffer chamber 40; the liquid transferring cavity 30 is spirally connected to the buffer cavity 40; the collecting member 10 is connected to the detection chamber 20 by a connecting section 117 of the collecting rod, wherein the absorbing element 12 is exposed outside the detection chamber 20; in the initial state, the absorbent member 12 is individually packaged in a plastic envelope in advance in order to keep it clean and sanitary.

Next, the plastic envelope on the absorbent member 12 is torn and removed, and the sample is collected by the absorbent member 12 (e.g., placed in the mouth of a subject to absorb saliva, or placed in a container in which a liquid sample is collected to absorb the sample), so that the absorbent member 12 is filled with the liquid sample.

Third, the absorbent member 12 of the collection member filled with the liquid sample is positioned directly over the orifice of the pipetting cavity 30 and the collection member 10 and the detection chamber 20 connected thereto are then inserted into the pipetting cavity 30 through the collection end 18 as shown in FIG. 6.

Fourth, the collecting member 10 is moved in the pipetting cavity 30 in the direction of insertion into the pipetting cavity 30, and when the gasket 80 on the outer wall of the detection chamber 20 reaches the pipetting cavity 30, the pipetting cavity 30 is sealed, as shown in FIG. 7.

Fifth, the collection member 10 continues to move within the pipetting cavity 30 in the direction of insertion into the pipetting cavity 30 until the conical projection 115 of the collection member reaches the sealing plate 70, as shown in FIG. 7.

Sixthly, the collecting part 10 and the detection cavity 20 are continuously moved in the same direction, the conical projection 115 of the collecting part pierces the sealing sheet 70 on the buffer cavity, the buffer cavity 40 is communicated with the pipetting cavity 30 to form a sealed cavity, the collecting part 10 is continuously moved and enters the buffer cavity 40, the sealed cavity formed by the buffer cavity 40 and the pipetting cavity 30 becomes small, the pressure in the cavity is increased, and the buffer solution 60 is extruded and flushed onto the absorbing element 12 to be mixed with the sample on the absorbing element 12; meanwhile, since the pressure in the sealed chamber is greater than the pressure in the detection chamber 20 (corresponding to atmospheric pressure), the mixed liquid flows into the detection chamber 20 along the flow guide grooves 112 of the absorbent member 12 and the collection rod and the lower steps 114 of the ribs. As shown in fig. 8.

Seventh, the liquid entering the detection chamber 20 reaches the cushion pad 23, is absorbed and buffered by the cushion pad 23, and then flows onto the test element 50 contacting the cushion pad 23 for detection, as shown in fig. 8.

Eighth, the detection result on the test element 50 is read to complete the detection.

Claims (4)

1. A sample collecting component for connecting with a detection device is characterized by comprising a collecting rod and an absorbing element with a cavity, wherein the absorbing element is sleeved on the collecting rod through the cavity; at least two ribs are arranged on the collecting rod, and a diversion trench is formed between the ribs.

2. The sample collection member of claim 1, wherein the ribs are of a stepped configuration; the absorbing element is located in the upper step.

3. The sample collection member of claim 1, wherein the collection rod has a tapered projection adjacent the collection end of the absorbent member.

4. The sample collection member for attachment to a test device of claim 1, wherein the attachment end of the collection rod is provided with a barb; the end of the barb is pointed and conical.

Images